Mitochondrial diseases
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- Опубликовано: 20 окт 2016
- Mitochondrial diseases are a group of disorders caused by genetic mutations. In this animation, Nature Video finds out how these diseases arise, and how new techniques can stop them being passed on from mother to child.
To learn more about mitochondrial diseases, check out the Primer: www.nature.com/articles/nrdp20...
and the PrimeView: www.nature.com/articles/nrdp20... 
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This is such an amazing video. Short, very well described, and the animation is simple and easy to understand. I love the analogy of the processes of the mitochondria with the gears. Well done and congrats!
Found this via The Lily Foundation. Thank you.
It will help put into words what I find I struggle with when I talk about my child who suffers with a mitochondrial disorder.
Please consider making a video on Hemophilia.
A tip to infographic video makers, when you use big jargon words please write it down for those who might want to research it further.
Learned 2 things from this
1. we get our mitchondria from our mothers
2. we can have 3 parents!
3 parents if you also have a dead brother or sister.
you can even more if you transplant normal functional genes in case of genetic diseases
The illustration is this video is compelling and easily comprehensible. Just an error I noticed, mtDNA codes for 13 subunits of the electron transport chain and oxidative phosphorylation while the nDNA codes for almost 1500 of the other mitochondrial proteins (other subunits of ETC and OP included)
some of the best science reporting I have ever seen
thanks
+
ikr. never thought something like this could be beautiful.
Thank you. Soo much,
Could you please give an example of a
maternal inheritance and a multifactorial inheritance trait or disease in cats?
How u made it easy is AMAZING!
I can't thank you enough for this explanation
Outstanding video...respect
my little brother has this disses so i was just trying to learn more about this
disease..
I saw a study that said that mitochondrias can also be herited from the father but in much more rare cases
www.google.com/amp/s/amp.livescience.com/64172-mitochondrial-dna-dads.html
maybe in other animals not in humans
@@nodehead9475 Not true, bro
Great video!
wonderful! Thank you!
Cells cells they're made of organelles, try to pull a fast one the cytoplasm gels, the nucleus takes over controlling everything, the party don't stop until the membrane blocks the scene
In Jesse's voice.. 'yeah, science!'
although most of this video is spot on, the information about the coding origin for mitochondrial proteins is absolutely INCORRECT. You said the NUCLEUS only codes for 13 proteins that function in mitochondrial function. YOU'VE GOT IT BACKWARDS! the mitochondrial DNA codes for 13 proteins in mitochondrial function while the NUCLEUS codes for the rest. PEOPLE DO YOUR RESEARCH!
Listen to it again... they say "The cell's nuclear DNA contains all but 13 proteins for the mitochondria. The rest are coded by the mitochondria themselves."
It's not the best wording because someone might not listen carefully enough but it's absolutely correct.
best vedio
Great ❤
Wont embryo screening a better approach than a tri-parent baby (because all maternal mitochondria are not defective)? Another approach is to take advantage of mitochondria in sperms.
this is helpfull
interesting topic
Thanks I will be using this in a Ted Ed Lesson soon
Love the Ted videos. Gl, and ty.
are you pronouncing the name Leigh as 'lay' advisedly?
I have lost my baby because of this disease. So do you say that if i want to have a baby again %100 he or she will have that disease for sure? Is it (3parentsbaby) the only way to have a healthy baby?
Aida Kazimova I’m going through testing to see if I have a mitochondrial disease and from my understanding it depends on your dna. Don’t quote me but I think there’s a certain gene a mother can carry that makes it either a 100% chance or not. So if you don’t have that gene you could potentially have a healthy baby. Does that make sense? This is a new concept to me. Still waiting on my genetic testing to come back so I’m not diving too deep into research until I know if I have itz
@Tgon Mwort That's bull.
@Tgon Mwort it is genetic
'It may be a controversial approach...' well if you keep telling people that it is 'controverisal' then they might feel that way, but there is no reason to take these silly people seriously. At some point you just gotta ignore the anti-science people who oppose everything from stem cells to vaccines to mitochondrial donations to GMO etc.
Of course a 3 parent baby is controversial. Who could possibly have a problem with that statement (except people who would profit by such a procedure).
@Tgon Mwort No it doesn't. Vitamins are supportive only. There is no cure for mito.
@Tgon Mwort no
how do you think prokaryotic cells have energy they don't have mitochondria that will need a lot of gluose aka a type of sugar because the form produce energy want more info do some research
the cell can produce energy without the mitochondria they will do anaerobic respiration but that person will have a lot of cramps because of fermentation.
Bruce Payne Whats your sources?
What is a solution to reduce cramping then will l carnitine help
This only says was can be done for what hasn't happened yet. What about the millions who suffer now, what can they do to reverse it?
Learned a new term- three parent baby.
😍😍😍
wow
2:00
I have mitochondrial disorder
is there any treatment for mitochondria
I’m sorry to ear that my guy
@@amalaly4306 Not currently. But a lot of people are working on it.
Is there any treatment on it?? Please give me some solutions .
The house is the mitochondria of the power cell got it
DNA is a code
And it has a [starting coding and a ending coding]
MTDNA its [starting coding and ending is different]
As it is [DNA its a different code all together
as it makes up the electron transfer chain
As the males MTDNA is in the tail of the sperm
it than falls off upon entry as it uses up its
energy to move iteself into the egg
so what one is left with is only
the Females MTDNA
for that kind
to use
XX and XY
Michael
Hindi me dijiye
Who’s here from corrie
Mitochondria is the powerhouse of the cell
Why could it be controversial to want a healthy offspring?
Another alteration of the organism produced by the introduction into the diet of foods for which we are not enough evolved. Like gluten. The consumption of proteins for which we are not evolved is very dangerous. Some gluten peptides pass to the blood when the intestine is damaged and disrupts the normal functioning of the body. Remeber , Amino acid combinations are like 0 and 1 on computers.
If some people follow a diet without gluten, dairy or processed foods, they heal without medicines. Better a paleo diet. This takes between 6 and 24 months.
Gluten + mitochondrial. DO YOUR RESEARCH! . research in celiac forums. .www.celiac.com
Diets do not make money to pharmaceutical companies and doctors are sellers of pharmaceuticals.
Diet is what's called an environmental factor. Mitochondrial diseases are genetic.
it's not caused by genetics, it's due to diet changes medications and anti-biotics
how do you know that? is there a biology/genetics textbook out there that you could recommend to me so I can see where you're getting your info from ? :)
Don't try to play God. Say "No, thank you" to 3 parent babies.
If you are not a woman of childbearing age with mitochondrial disease you have no right to an opinion.
Dude it's fine as long as it helps the baby
@@humanbean8590 It is true I could never fully empathize with a woman mitochondrial disease. However try to apply your logic to every circumstance ... It is terribly faulty logic. A judge would hardly be able to judge anything. Of course I have a right to an opinion. I do desire for everyone to be healthy but not necessarily at any cost. I guess we will see how the science goes.
@@gmdrandom6287 I hold the opinion that we venture onto dangerous grounds when we attempt to play God.
So what are the other options to alter DNA expression? IMO, western medicine should put more effort into helping people achieve favorable DNA expression through things like nutrition, exercise, and stress management; that is to say a more natural approach to health rather than a never ending supply of patented medicine.
And no one would know if the baby is actually helped for many years. When we start tinkering with designing babies, you just don't know if a life would be destroying instead.
@@RealEstateInsider247 scientists aren't trying to "play god". They're trying to save lives