Organometallic Reagents and Reactions - Grignard, Gilman, Organolithium

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  • Опубликовано: 4 июл 2024
  • Leah4sci.com/Metallic presents: Organometallic Reagents, formation and Reactions overview including the Grignard, Organolithium and Gilman Reagents
    📺Watch Next: Grignard Reagent, Reaction, Mechanism and Shortcut • Grignard Reagent, Reac...
    Need help with Orgo? Download my free guide ’10 Secrets to Acing Organic Chemistry’ HERE: leah4sci.com/orgo-ebook/
    In this video, you’ll learn about the 3 most common organometallic reactions including how to create the individual reagents, similarities and differences, and how they react with different molecule types
    This includes the Grignard reagent, organolithium, and Gilman or organocuprate.
    You’ll learn how organometallics can be useful in organic synthesis questions for chain elongation, ring-opening reactions and more.
    You’ll also understand why the carbon in an organometallic reagent is so reactive, acting as the nucleophile in a reaction.
    ↪ Links & Resources Mentioned In This Video ↩
    ▸Grignard/Organometallics Series Leah4sci.com/Metallic
    ▸Grignard Reagent Tutorial + Cheat Sheet Leah4sci.com/Grignard
    ▸Polar Covalent Bonding • Ionic, Polar Covalent ...
    ▸Nucleophile and Base Analysis for Substitution-Elimination • Nucleophile and Base A...
    ▸Oxidation and Reduction Series + Cheat Sheet Leah4sci.com/redox
    ▸Michael Addition Leah4sci.com/Enolate
    - - - - - - - - - - - - - - - - - - - - - - - -
    ⏱ In this video:
    [0:19] Defining Organometallic
    [1:48] Comparing Reactivity of Organometallics
    [2:53] Grignard Reagent - Organomagnesium
    [5:27] Grignard Reactions Overview
    [6:12] Organolithium Reagent
    [7:47] Gilman Reagent - Organocuprate
    - - - - - - - - - - - - - - - - - - - - - - - -
    Follow along with your semester by using my Orgo Syllabus Companion: leah4sci.com/syllabus
    For more in-depth review including practice problems and explanations, come join my online membership site, the Organic Chemistry Study Hall: leah4sci.com/join
    ❓Questions? Ask me here: Leah4sci.com/contact
    👩‍🏫 For private online tutoring visit my website: leah4sci.com/organic-chemistry
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Комментарии • 56

  • @xerib
    @xerib 6 месяцев назад +1

    Leah, I really have to thank you for a deeper understanding in organic chemistry!!

    • @Leah4sci
      @Leah4sci  6 месяцев назад +1

      You're very welcome! Glad my videos are helping

  • @Souluble_87
    @Souluble_87 10 дней назад

    Thank u mam i was crying that i didnt understand this in coaching
    U simplified it a lot

    • @Leah4sci
      @Leah4sci  9 дней назад

      I'm sorry to hear this topic had you in tears, but I'm glad I was able to help clear things up for you!

  • @kozkirsehirli
    @kozkirsehirli Год назад +1

    I love u queeennn, u make this so easy 🤩🤩

    • @Leah4sci
      @Leah4sci  Год назад

      Thank you so much! glad to help

  • @MsAbby.3
    @MsAbby.3 9 месяцев назад +3

    Thanks ms Leah ❤

    • @Leah4sci
      @Leah4sci  9 месяцев назад

      You are so welcome

  • @abirdas3955
    @abirdas3955 Год назад +6

    After a long time you are finally back, we would love to watch your organic chemistry videos regular basis..

    • @Leah4sci
      @Leah4sci  Год назад +1

      Thank you and you are most welcome to. With over 300 videos posted you should hopefully find plenty on any topic you're currently working on

    • @happysinghfrompatiala964
      @happysinghfrompatiala964 Год назад +1

      @@Leah4sci keep uploading mam

    • @JustLikeYouYT
      @JustLikeYouYT Год назад

      @@happysinghfrompatiala964 skm sir proud student

    • @irshadullahkhan6800
      @irshadullahkhan6800 Год назад

      ​@@Leah4scihi mam

  • @BOLYANA
    @BOLYANA Месяц назад

    Very clear..Thanks

    • @Leah4sci
      @Leah4sci  Месяц назад

      You're very welcome!

  • @macho8555
    @macho8555 Год назад +1

    Thank youuuu 💐

    • @Leah4sci
      @Leah4sci  Год назад +1

      You're very welcome

  • @skandaswaroop
    @skandaswaroop Год назад

    Hello mam
    I am a student studying in high school in India
    I really loved your way of teaching organic chemistry
    There is no online tutor in India who can make organic chemistry this easy
    Thank you

    • @Leah4sci
      @Leah4sci  Год назад

      You're very welcome!

  • @user-qk6nm1xp6c
    @user-qk6nm1xp6c Месяц назад

    Hey, I love your videos. It has helped me out so much. Thank you.
    Can you make an in-depth video on gilmans reagent, it’s a little difficult to understand.

    • @Leah4sci
      @Leah4sci  Месяц назад

      Glad my videos are helping and thanks for the suggestion. I don't know when but I will consider it at some point in the future

  • @hashidulislam2911
    @hashidulislam2911 Год назад +2

    I dont have these topics in my syllabus but i understood n i love it more❣️❣️🥰🥰🥰🥰🥰

    • @Leah4sci
      @Leah4sci  Год назад +1

      Awesome that you're understanding it! This usually shows up in organic chemistry part 2

    • @hashidulislam2911
      @hashidulislam2911 Год назад +1

      Yeah its great🥰🥰

  • @msvbalasubramanyam4601
    @msvbalasubramanyam4601 Год назад +1

    Hi mam your voice is very nice and your way of teaching is very nice ❤❤❤❤

    • @Leah4sci
      @Leah4sci  Год назад +1

      Thank you for the compliment!

  • @biswaditya938
    @biswaditya938 Год назад +1

    Thank you maam

  • @anshdesai8238
    @anshdesai8238 Год назад +1

    Tommorow is my exam this video help me alot

    • @Leah4sci
      @Leah4sci  Год назад

      I'm so glad to hear that! I hope the exam went well.

  • @ChemSurvival
    @ChemSurvival 9 месяцев назад +1

    After all of the MO theory and structural analysis is done (a tough task in itself), it is always about just two things: 1. where do the electrons want to go? 2. Can they get there? If not, see step one for the next easiest pathway and repeat!.

    • @Leah4sci
      @Leah4sci  9 месяцев назад +2

      I like it! So many Organic mechanisms can be simplified by just thinking about the electrons flowing from high density to low density situations. Thanks for watching.

  • @bakybabyx
    @bakybabyx Год назад

    Thanks for the awesome vid :)
    May I ask why the Gilman reagent [(CH3)2CuLi] wouldn't just attack the carbonyl carbon?
    Also do you have a vid on latent polarity and why it occurs?

    • @Leah4sci
      @Leah4sci  Год назад +1

      You are very welcome!
      Regarding why the carbonyl doesn't get attacked, this is considered a weaker attacker and follows a 1,4 addition mechanism. (Review Michael addition for this.)
      As for latent polarity, I'm sorry but I don't have a video on this.

    • @bakybabyx
      @bakybabyx Год назад

      @@Leah4sci Ah brilliant, thanks for the reply :)

  • @amberhealth9792
    @amberhealth9792 10 месяцев назад +1

    Awesome

    • @Leah4sci
      @Leah4sci  10 месяцев назад

      thank you!

  • @kakherbi
    @kakherbi Год назад +1

    Can you tell us how to make a video like this? Can you share what devices you use

    • @Leah4sci
      @Leah4sci  Год назад +1

      Let's keep the comments relevant to the video topic please.

  • @tientaicao4200
    @tientaicao4200 Год назад +1

    thanks,by the way can u tell me the product of this reaction?:C3H5RCOOH+H2O->?

    • @Leah4sci
      @Leah4sci  Год назад

      I'm sorry, but I don't offer tutoring over social media. For help with questions like this and more, I recommend joining the organic chemistry study hall. Details: leah4sci.com/join or contact me through my website leah4sci.com/contact/

  • @msvbalasubramanyam4601
    @msvbalasubramanyam4601 Год назад +1

    What are your best organic chemistry books reference ❤

    • @Leah4sci
      @Leah4sci  Год назад +1

      I prefer my own resources over any textbook! Find my entire free Orgo collection on my website at Leah4sci.com/syllabus.
      Or, for details on my membership site and resources, visit Leah4sci.com/join or contact me at Leah4sci.com/contact

  • @arvindthakare5592
    @arvindthakare5592 Год назад +1

    I am really struggling in physical chemistry can you pls help me

    • @Leah4sci
      @Leah4sci  Год назад

      I'm sorry, but I don't offer tutoring over social media. Additionally, I am not a Physical Chemistry tutor. I help students with Organic Chemistry through my Organic Chemistry Study Hall.
      Details for that found at leah4sci.com/join or contact me through my website leah4sci.com/contact/

  • @techofbengal3137
    @techofbengal3137 Год назад +1

    Reaction with acid chloride shoul be addition and elimination... Therefore first acetone will form..

    • @Leah4sci
      @Leah4sci  Год назад

      Are you implying there's a mistake in the video? If yes, thank you for bringing it to my attention. which reaction? (what time in the video?)

    • @techofbengal3137
      @techofbengal3137 Год назад

      @@Leah4sci reaction with acid halide ang grignard reagent... It should be addition via elimination... I mean grignard will react untill u use water... In first step u did not use water.. So first acetone will form... Then again grirnard nucleoplhilic addition occur..

    • @techofbengal3137
      @techofbengal3137 Год назад

      @@Leah4sci in the thumble given...

    • @techofbengal3137
      @techofbengal3137 Год назад

      @@Leah4sci otherwise u r wright... The answer will be decided by the given question....

    • @Leah4sci
      @Leah4sci  Год назад

      @@techofbengal3137 I still don't see an error in the video. Water was not added until after the second addition of the Grignard reagent to form the alcohol. An acid halide reacts with excess Grignard reagent to form a tertiary alcohol, NOT a ketone.

  • @rahulradhakrishnan2964
    @rahulradhakrishnan2964 Год назад

    Hi mam which software is using to create this animation video

    • @Leah4sci
      @Leah4sci  Год назад +1

      Let's keep the comments relevant to the video topic please. Thanks!

    • @rahulradhakrishnan2964
      @rahulradhakrishnan2964 Год назад +1

      @@Leah4sci not only you are creating the chemistry video in you tube. You thought all science and everything is in your mind, actually you got from alone.
      Anyway I got your software by the helps of artificial intelligence, I just paste your video link and asked to artificial intelligence, like below.
      Hi their, can you just tell me which software is used to create this video, here I am pasting the youtube video link.
      Lol Suddenly with in fractions of second the AI gave me the answer.
      😂