Bioinformatics part 2 Databases (protein and nucleotide)

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This video is about bioinformatics databases like NCBI, ENSEMBL, ClustalW, Swisprot, SIB, DDBJ, EMBL, PDB, CATH, SCOPE etc.
Bioinformatics Listeni/ˌbaɪ.oʊˌɪnfərˈmætɪks/ is an interdisciplinary field that develops and improves on methods for storing, retrieving, organizing and analyzing biological data. A major activity in bioinformatics is to develop software tools to generate useful biological knowledge.
Bioinformatics uses many areas of computer science, mathematics and engineering to process biological data. Complex machines are used to read in biological data at a much faster rate than before. Databases and information systems are used to store and organize biological data. Analyzing biological data may involve algorithms in artificial intelligence, soft computing, data mining, image processing, and simulation. The algorithms in turn depend on theoretical foundations such as discrete mathematics, control theory, system theory, information theory, and statistics. Commonly used software tools and technologies in the field include Java, C#, XML, Perl, C, C++, Python, R, SQL, CUDA, MATLAB, and spreadsheet applications.
In order to study how normal cellular activities are altered in different disease states, the biological data must be combined to form a comprehensive picture of these activities. Therefore, the field of bioinformatics has evolved such that the most pressing task now involves the analysis and interpretation of various types of data. This includes nucleotide and amino acid sequences, protein domains, and protein structures.[9] The actual process of analyzing and interpreting data is referred to as computational biology. Important sub-disciplines within bioinformatics and computational biology include:
the development and implementation of tools that enable efficient access to, use and management of, various types of information.
the development of new algorithms (mathematical formulas) and statistics with which to assess relationships among members of large data sets. For example, methods to locate a gene within a sequence, predict protein structure and/or function, and cluster protein sequences into families of related sequences.
The primary goal of bioinformatics is to increase the understanding of biological processes. What sets it apart from other approaches, however, is its focus on developing and applying computationally intensive techniques to achieve this goal. Examples include: pattern recognition, data mining, machine learning algorithms, and visualization. Major research efforts in the field include sequence alignment, gene finding, genome assembly, drug design, drug discovery, protein structure alignment, protein structure prediction, prediction of gene expression and protein--protein interactions, genome-wide association studies, and the modeling of evolution.
Bioinformatics now entails the creation and advancement of databases, algorithms, computational and statistical techniques, and theory to solve formal and practical problems arising from the management and analysis of biological data.
Over the past few decades rapid developments in genomic and other molecular research technologies and developments in information technologies have combined to produce a tremendous amount of information related to molecular biology. Bioinformatics is the name given to these mathematical and computing approaches used to glean understanding of biological processes. Source of the article published in description is Wikipedia. I am sharing their material. Copyright by original content developers of Wikipedia.
Link- en.wikipedia.org/wiki/Main_Page

[@atharvasawant287]

All hail our lord and savior Shomu who in our time of great need saw in his omniscience to create these youtube videos to save us from failure or worse. We should reply in kind his blessings by subscribing and liking his
videos.

[@cakshacourses1048]

I have found this material very useful to understand the basics of bioinformatics so i have created a course out of it and posted in caksha

[@mehulsharma5228]

Are the definitions of Primary and Secondary data hard and fast ? If I'm say on an alien planet searching for the components of an alien's genetic material can I create a database with say different atoms of Carbon, Nitrogen, etc. which is my primary db and then my 2ndry db will have maybe a single monomeric biomolecule like an amino acid or a nucleotide which these Cs and Ns will arrange themselves into

[@aelitastones8012]

I LOVE SCIENCE!

[@priyaselvam764]

Is there any tools to identify sequences based on functions?

[@misbahmubashar9770]

Hi! Sir Shomu, please start a complete course about comparative genomic analysis with practical and on-time performance with real data. We are struggling very much to find a good course with on-time practice. It will be a very great help for us. Thank You!

[@shomusbiologyofficial]

Okay

[@MHas-wq9qp]

Protein id is unique identifier to record the nucleotide sequences in the GenBank, does not change when record is updated. Is it true or false?

[@bioinformaticstools6178]

Knowledgeable...Great Jobe

[@GaurMansi]

thanks . helped a lot . now I have developed a hope that yes I can score in this subject too .

[@aravindsai9508]

THANK YOU VERY MUCH SIR

[@ummekhadiza7288]

Your pronunciation is very clear to understand.

[@shomusbiologyofficial]

You're welcome. Glad to hear that you're getting benefit from my lectures

[@ismatazizi9021]

Thank you. God Bless you.

[@shomusbiologyofficial]

Thank you

[@narayanaruthwekmamillapall713]

Thank you for your detailed explanation

[@shomusbiologyofficial]

Thank you so much for appreciating my efforts

[@mayurbiotech1657]

I love ur videos, u have saved me and given a hope for interview during bioinformatics PhD

[@ramratansankhla]

what are you doing currently ,, I am wishing to join bioinformatics , should i ??

[@mayurbiotech1657]

@@ramratansankhla I changed my topic to protein nanotechnology and my experiments are of wet lab buddy

[@ramratansankhla]

oo , ok all the best ... also if you know someone in india who is doing bsc bioinformatics then once ask him to contact me please ,@@mayurbiotech1657

[@dr.nileshkumarpandya7595]

Helpful in understanding data types of bioinformatics

[@shomusbiologyofficial]

You're welcome

[@iztibamallikdeeba6914]

Thank you very much! Please keep up.

[@shomusbiologyofficial]

Thank you

[@farahshahjin2359]

awesome accumulation of info. helps a lot. thanks.

[@shomusbiologyofficial]

Thank you.

[@saraben2262]

Can .you please explaine what's the different between database and databank??

[@mehulsharma5228]

What on earth is "new sequence" of DNA ? If I'm extracting DNA of some organism X say ATGC.AC... , how am I supposed to know it is different ? Nucleotides can after all be arranged in any random manner (bound by complementarity rule).

[@peter_dockit]

you can check bioinformatic tools to perform gene sequence comparisons using FASTA or others

[@vyomalchaudhari2204]

THANKS FOR DELIVERING IMP NOTES....

[@ramratansankhla]

what are you doing bro currently ??

[@RAJESHDAS-rn7od]

Thanks a Lot :)

[@shomusbiologyofficial]

You're welcome

[@zapy422]

Thank for your video
Good explanation, I'll try to follow the rest of the serie

[@monalipatil1593]

Please help me to find answer-
All the coordinate files (.pdb) of Three dimensional protein structures that have been published are stored in the same online databases. This database is
(1) ExPASy
(2) RCSB
(3) PubMed
(4) PSIPERD
(5) OMIM

[@avinashgaikwad8389]

yes

[@chandanlalkarn8]

good tutorial

[@MrSkullSociety]

thanks a lot bro. your videos helped me greatly

[@shomusbiologyofficial]

You're welcome

[@davidjoshua6890]

Junhong what are u doing

[@baaliou2157]

thank you

[@MBA953]

tanks a lots of sir....this vedio greatly helpful for me.....

[@shomusbiologyofficial]

You're welcome

[@sohailahmed7283]

Thanks a lot again

[@shomusbiologyofficial]

You're welcome

[@randomnone8463]

Great vid!

[@shomusbiologyofficial]

Thanks

[@NARANGA.MITTAYI.MALAYALAM]

👍🏻👍🏻👍🏻

[@shubhamkumawat33]

sir pls suggest book of bioinformatics for dbt bet jrf

[@dreamer5911]

Thank you sir

[@shomusbiologyofficial]

You're welcome

[@snehasri6790]

Hi sir, for bioinformatics we need to learn any computer Programming language like C, C+,java

[@chubbycat8445]

python

[@ori2022]

Would you show us the practical for Nucleotide sequence databases search

[@shomusbiologyofficial]

In a separate video

[@davidjoshua6890]

Hey bro i just finished my 12th how to get bioinformatics as my career and what collage should i chose

[@davidjoshua6890]

Plz reply

[@reddyyogeshwari]

hi suman which books can be read for entracne exam for phd can u tell me please

[@muskanmittal6444]

I want to ask what type of computer languages are necessary for bioinformatics degree

[@shomusbiologyofficial]

Python

[@muskanmittal6444]

For python do we need to learn c first?

[@shaikabdul9042]

Hii plz u can give notes of biological data bases

[@rahulkarmakar8826]

lectures are good but 'data' is already plural, singular is 'datam'

[@djm.a.k7051]

Kaunsi University me padhe ho datem ?

[@thevarshney101]

I think you should be more apt instead of repeating the same point thrice because after a point it starts getting onto the viewer's nerve.

[@uvedalewood1826]

Shomu, if I have a question to ask you about molecular dynamics simulation, can I send you a private message via RUclips?

[@robin_kumar_Tandon]

please in hindi

[@ansatabassum7007]

vedio volume is vry low
very difficult yo listen

[@shomusbiologyofficial]

Sorry

[@georgiivdovin6543]

Ah yes, the EU, aka Germany

[@poopsintub]

4:41 Utorrent

[@manishayadav-oc9rp]

Thanks sir

[@shomusbiologyofficial]

You're welcome