How one of Nature's Most Complex Molecules Is Made: Synthesis of Taxol's "Complicated Cousin"

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  • Опубликовано: 4 окт 2024

Комментарии • 150

  • @Khalastas
    @Khalastas 3 года назад +32

    Fantastic, what a brilliant synthesis. The BHT serendipity was great. Thanks !

    • @ChemNews
      @ChemNews 2 года назад

      Hi, perhaps you will like my channel about recent chemistry publications. Just released a video about the recent work of Benjamin List (the guy with the 2021 Nobel prize) ruclips.net/user/ChemNewsvideos

  • @asensniper
    @asensniper 3 года назад +11

    When this channel uploads, I have a good day

    • @ChemNews
      @ChemNews 2 года назад

      Hi, perhaps you will like my channel about recent chemistry publications. Just released a video about the recent work of Benjamin List (the guy with the 2021 Nobel prize) ruclips.net/user/ChemNewsvideos

  • @thinkpoddlesp9712
    @thinkpoddlesp9712 3 года назад +11

    This video makes me realise I need to go over my year 1 undergrad chemistry notes again

    • @ChemNews
      @ChemNews 2 года назад

      Hi, perhaps you will like my channel about recent chemistry publications. Just released a video about the recent work of Benjamin List (the guy with the 2021 Nobel prize) ruclips.net/user/ChemNewsvideos

  • @alexanderliang2437
    @alexanderliang2437 3 года назад +10

    I'm an undergraduate chemistry student at a university in Taiwan, and RUclips has finally recommended to me the video I really want to watch, instead of random/clickbaiting videos.
    12:00 Is where I start to have 0% understanding lol.

    • @ChemNews
      @ChemNews 2 года назад

      Hi, perhaps you will like my channel about recent chemistry publications. Just released a video about the recent work of Benjamin List (the guy with the 2021 Nobel prize) ruclips.net/user/ChemNewsvideos

    • @Torteufel
      @Torteufel 2 года назад

      maybe you should consult the paper. it is greatly written and perfectly understandable with a little knowledge of organic chemistry

  • @azuthaindra4586
    @azuthaindra4586 3 года назад +5

    So stunning.
    I'm not organic folk, though. yet it's really interesting to watch.
    Keep your great work.
    Thanks!

    • @ChemNews
      @ChemNews 2 года назад

      Hi, perhaps you will like my channel about recent chemistry publications. Just released a video about the recent work of Benjamin List (the guy with the 2021 Nobel prize) ruclips.net/user/ChemNewsvideos

  • @alexmoore2466
    @alexmoore2466 3 года назад +9

    a beautiful synthesis. Pericylic mechanisms are so powerful in the construction of these stereogenic centres. Appreciate the detail and care in presentation.

    • @ChemNews
      @ChemNews 2 года назад

      Hi, perhaps you will like my channel about recent chemistry publications. Just released a video about the recent work of Benjamin List (the guy with the 2021 Nobel prize) ruclips.net/user/ChemNewsvideos

  • @SynthesisWorkshopVideos
    @SynthesisWorkshopVideos 3 года назад +5

    Very well done! Congrats on putting together a really great video on this complex target!

    • @totalsynthesis
      @totalsynthesis  3 года назад +3

      Thank you! Great work on your videos as well, I featured you on my channel page if that helps in any way :-)

    • @ChemNews
      @ChemNews 2 года назад

      Hi, perhaps you will like my channel about recent chemistry publications. Just released a video about the recent work of Benjamin List (the guy with the 2021 Nobel prize) ruclips.net/user/ChemNewsvideos

  • @MrPegaMenis
    @MrPegaMenis 3 года назад +5

    crazy synthesis 💯

  • @mpcassi
    @mpcassi 3 года назад +16

    Great video! One note--the molecule at 5:13 was developed by BMS, not Pfizer. I know because I was on the team that made hundreds of kg of it. My first project in industry and a fun project as well.

    • @totalsynthesis
      @totalsynthesis  3 года назад +5

      Thanks for clarifying. Of course you’re right, the original inhibitor was BMS and just the BCP analog was Pfizer.

    • @ChemNews
      @ChemNews 2 года назад

      Hi, perhaps you will like my channel about recent chemistry publications. Just released a video about the recent work of Benjamin List (the guy with the 2021 Nobel prize) ruclips.net/user/ChemNewsvideos

    • @petitkus4408
      @petitkus4408 Год назад

      🤯

  • @pinobear5313
    @pinobear5313 3 года назад +32

    based molecules

    • @ChemNews
      @ChemNews 2 года назад

      Hi, perhaps you will like my channel about recent chemistry publications. Just released a video about the recent work of Benjamin List (the guy with the 2021 Nobel prize) ruclips.net/user/ChemNewsvideos

    • @petevenuti7355
      @petevenuti7355 Год назад

      Are you on the "that chemist" discord or something?

    • @petevenuti7355
      @petevenuti7355 Год назад

      @@richardlyman2961 that will do it... anything drug related could get you in trouble too...

  • @chentianwei2071
    @chentianwei2071 3 года назад +1

    I have just read this original literature in July. Very impressvie for this total synthesis. When I was reading, I followed this literature and drew every steps in this synthesis. Art of total synthesis

    • @ChemNews
      @ChemNews 2 года назад

      Hi, perhaps you will like my channel about recent chemistry publications. Just released a video about the recent work of Benjamin List (the guy with the 2021 Nobel prize) ruclips.net/user/ChemNewsvideos

  • @patelarpit1359
    @patelarpit1359 3 года назад +5

    Great to know what was the initial thought process of total synthesis of these complex molecules..Thank u so much for providing this informative content..
    Lots of Love From INDIA 🤩🤩

    • @ChemNews
      @ChemNews 2 года назад +1

      Hi, perhaps you will like my channel about recent chemistry publications. Just released a video about the recent work of Benjamin List (the guy with the 2021 Nobel prize) ruclips.net/user/ChemNewsvideos

  • @SunilKumar-ci9dr
    @SunilKumar-ci9dr Год назад +1

    My PhD is on this complex molecule,Taxol.. Nice to be a part of its synthetic studies...

  • @jasonking8144
    @jasonking8144 3 года назад +3

    I love your channel. You are a master.

    • @ChemNews
      @ChemNews 2 года назад

      Hi, perhaps you will like my channel about recent chemistry publications. Just released a video about the recent work of Benjamin List (the guy with the 2021 Nobel prize) ruclips.net/user/ChemNewsvideos

  • @sunrisetenshi1054
    @sunrisetenshi1054 Год назад +1

    I vote for video with explaining of carborane acid synthesis ^_^

  • @builtin2761
    @builtin2761 3 года назад +3

    Great synthesis and great video. Amazing!

    • @ChemNews
      @ChemNews 2 года назад

      Hi, perhaps you will like my channel about recent chemistry publications. Just released a video about the recent work of Benjamin List (the guy with the 2021 Nobel prize) ruclips.net/user/ChemNewsvideos

  • @supriyodas8915
    @supriyodas8915 2 года назад +2

    Just fantastic!

  • @dr.dirlewangerphdnobelpeac9967
    @dr.dirlewangerphdnobelpeac9967 3 года назад +2

    Your videos are brilliant, I really hope you will post more often in the future

    • @ChemNews
      @ChemNews 2 года назад

      Hi, perhaps you will like my channel about recent chemistry publications. Just released a video about the recent work of Benjamin List (the guy with the 2021 Nobel prize) ruclips.net/user/ChemNewsvideos

  • @supriyodas8915
    @supriyodas8915 2 года назад +1

    Need more videos like that.

  • @SciEch92
    @SciEch92 3 года назад +2

    this videos are awesome !! keep doing this fantastic job!

    • @ChemNews
      @ChemNews 2 года назад

      Hi, perhaps you will like my channel about recent chemistry publications. Just released a video about the recent work of Benjamin List (the guy with the 2021 Nobel prize) ruclips.net/user/ChemNewsvideos

  • @R0obiiin
    @R0obiiin 3 года назад +1

    A very nice video indeed, thank you for making them!

    • @ChemNews
      @ChemNews 2 года назад

      Hi, perhaps you will like my channel about recent chemistry publications. Just released a video about the recent work of Benjamin List (the guy with the 2021 Nobel prize) ruclips.net/user/ChemNewsvideos

  • @shaunkelly7223
    @shaunkelly7223 3 года назад

    Very nice video, glad you highlighted this one as I was not aware of this science publication of her

    • @ChemNews
      @ChemNews 2 года назад

      Hi, perhaps you will like my channel about recent chemistry publications. Just released a video about the recent work of Benjamin List (the guy with the 2021 Nobel prize) ruclips.net/user/ChemNewsvideos

  • @magician100
    @magician100 2 года назад

    Why this Chanel not putting videos anymore, very interesting stuff

  • @roysteneker6554
    @roysteneker6554 3 года назад +3

    Great video once again! Keep up the good work :)

    • @ChemNews
      @ChemNews 2 года назад

      Hi, perhaps you will like my channel about recent chemistry publications. Just released a video about the recent work of Benjamin List (the guy with the 2021 Nobel prize) ruclips.net/user/ChemNewsvideos

  • @MinecrafterRedstoner
    @MinecrafterRedstoner 3 года назад +4

    Hi!
    I'm graduating my B. Sc in chemistry, and i'm currently doing a chemistry methods course.
    We learn how to synthesise polyfunctionnal complex molecules. We had to explain the uses of all the protecting groups in litterature.
    Your videos really helped me to understand why using MOM chloride in certain cases instead of Boc.
    Your videos help (probably) lots of people, and we are super greatful of having your help!
    Keep it up :)

    • @totalsynthesis
      @totalsynthesis  3 года назад +1

      Very happy to hear this! Wishing you all the best for your courses :)

    • @ChemNews
      @ChemNews 2 года назад

      Hi, perhaps you will like my channel about recent chemistry publications. Just released a video about the recent work of Benjamin List (the guy with the 2021 Nobel prize) ruclips.net/user/ChemNewsvideos

  • @luca-jminecraftxx9960
    @luca-jminecraftxx9960 3 года назад +2

    I love your unique topics and approach to organic sinthesys, you might not be able to upload often but quality never drops,keep it up!!

    • @ChemNews
      @ChemNews 2 года назад

      Hi, perhaps you will like my channel about recent chemistry publications. Just released a video about the recent work of Benjamin List (the guy with the 2021 Nobel prize) ruclips.net/user/ChemNewsvideos

  • @Mr.Cucumba
    @Mr.Cucumba 2 года назад

    Thank you for sharing! Just searched for Taxol Synthesis as I got news today that I'm gonna do my bachelor in the AG of Prof. Gaich. Really exciting.

    • @totalsynthesis
      @totalsynthesis  2 года назад +1

      Amazing. All the best!

    • @Mr.Cucumba
      @Mr.Cucumba Год назад

      @@totalsynthesis I've got some questions concerning the use of the building blocks (dienophiele and diene). Would it be possible to get some more insight into the mechanism of the [2+2] cycloaddition as well as the reasons for choosing these two substrates? Sure, regio- and diastereoselektivity are key to achieving the endo-diels alder adduct, but i would like to know some more detail. Since you put all this effort into this video, maybe you want to pass some of your findings to me?
      regards

  • @knivesnico8775
    @knivesnico8775 3 года назад +5

    you uploaded this in the middle of an LSD trip this is NOT a coincidence what
    WHAT

    • @_iakvb771
      @_iakvb771 3 года назад +5

      nightmare nightmare nightmare

    • @lucidchem
      @lucidchem 3 года назад

      good travels!
      here's a video if you need to CALM down (click on the link): ruclips.net/video/HFacq4vKMw8/видео.html

    • @knivesnico8775
      @knivesnico8775 3 года назад +2

      oh and btw it was an excelent video and very beautiful experience believe it or not, for some reason his voice has this smile inducing undertone, very charming
      the reactions were fascinating as well, very good experience overall

    • @knivesnico8775
      @knivesnico8775 3 года назад

      @@lucidchem thankfully i didnt need your video, but thank you!

    • @lucidchem
      @lucidchem 3 года назад

      @@knivesnico8775 No worries, I'm glad to hear that!

  • @masonrunning
    @masonrunning 2 года назад +1

    thanks

  • @definetlynotacomment1184
    @definetlynotacomment1184 3 года назад +2

    Total Synthesis:
    -Covers decades of org Chem history, about a group of Molecules only known by
    people who actually studied/ worked in chem and total nerds.
    -Introduces the audience to a absolute Raid Boss of a molecule (in terms of complexity)
    -Covers the development, retrosynthetic considerations and most of the 26 step total synthesis.
    And he did all of that with in a little over 20 minutes and with a calming voice.
    Beyond Based.
    PS: I was really surprised how how stable that Peroxide was. That Synthesis was a wild ride.

    • @totalsynthesis
      @totalsynthesis  3 года назад +1

      Love you!

    • @ChemNews
      @ChemNews 2 года назад

      Hi, perhaps you will like my channel about recent chemistry publications. Just released a video about the recent work of Benjamin List (the guy with the 2021 Nobel prize) ruclips.net/user/ChemNewsvideos

  • @crabcrab2024
    @crabcrab2024 3 года назад

    Thank you so much for your work! You are awesome.

    • @ChemNews
      @ChemNews 2 года назад

      Hi, perhaps you will like my channel about recent chemistry publications. Just released a video about the recent work of Benjamin List (the guy with the 2021 Nobel prize) ruclips.net/user/ChemNewsvideos

    • @crabcrab2024
      @crabcrab2024 2 года назад +1

      @@ChemNews With great pleasure! Thank you.

    • @ChemNews
      @ChemNews 2 года назад

      @@crabcrab2024 Thanks!

  • @T.Transmutations
    @T.Transmutations 3 года назад

    Fantastic!

    • @ChemNews
      @ChemNews 2 года назад

      Hi, perhaps you will like my channel about recent chemistry publications. Just released a video about the recent work of Benjamin List (the guy with the 2021 Nobel prize) hruclips.net/video/ELy3uR9Bsm4/видео.html

  • @samueldeschwanden3065
    @samueldeschwanden3065 3 года назад +1

    I can't follow you longer than some seconds because I have no clue of the topic but I like to listen to your beautifully calming voice ❤️

    • @ChemNews
      @ChemNews 2 года назад

      Hi, perhaps you will like my channel about recent chemistry publications. Just released a video about the recent work of Benjamin List (the guy with the 2021 Nobel prize) ruclips.net/user/ChemNewsvideos

  • @pokhuthird1194
    @pokhuthird1194 2 года назад

    nice video

  • @medicalbiochemistry_
    @medicalbiochemistry_ 3 года назад +1

    Great video

    • @ChemNews
      @ChemNews 2 года назад

      Hi, perhaps you will like my channel about recent chemistry publications. Just released a video about the recent work of Benjamin List (the guy with the 2021 Nobel prize) hruclips.net/video/ELy3uR9Bsm4/видео.html

  • @m4sterbr0s
    @m4sterbr0s 3 года назад

    Another great video

    • @ChemNews
      @ChemNews 2 года назад

      Hi, perhaps you will like my channel about recent chemistry publications. Just released a video about the recent work of Benjamin List (the guy with the 2021 Nobel prize) hruclips.net/video/ELy3uR9Bsm4/видео.html

  • @msp7124
    @msp7124 3 года назад +1

    Absolut madlads

  • @serbianfemboy
    @serbianfemboy 3 года назад

    love the vids man

    • @ChemNews
      @ChemNews 2 года назад

      Hi, perhaps you will like my channel about recent chemistry publications. Just released a video about the recent work of Benjamin List (the guy with the 2021 Nobel prize) hruclips.net/video/ELy3uR9Bsm4/видео.html

  • @bsheaves
    @bsheaves 3 года назад +1

    Actually got to watch Tanja Gaich give a talk on this. My mouth was in the floor for 30 straight minutes

  • @alexandraschneider5651
    @alexandraschneider5651 3 года назад +1

    Fantastic video!!!

    • @ChemNews
      @ChemNews 2 года назад

      Hi, perhaps you will like my channel about recent chemistry publications. Just released a video about the recent work of Benjamin List (the guy with the 2021 Nobel prize) hruclips.net/video/ELy3uR9Bsm4/видео.html

  • @mevnesldau8408
    @mevnesldau8408 3 года назад

    wow, the dearomatization cycloaddition is really nice!

    • @ChemNews
      @ChemNews 2 года назад

      Hi, perhaps you will like my channel about recent chemistry publications. Just released a video about the recent work of Benjamin List (the guy with the 2021 Nobel prize) ruclips.net/user/ChemNewsvideos

  • @kiranus8286
    @kiranus8286 3 года назад

    Awesome👏

    • @ChemNews
      @ChemNews 2 года назад

      Hi, perhaps you will like my channel about recent chemistry publications. Just released a video about the recent work of Benjamin List (the guy with the 2021 Nobel prize) hruclips.net/video/ELy3uR9Bsm4/видео.html

  • @ismaelamarillo7488
    @ismaelamarillo7488 3 года назад +1

    Could you some day talk about the total synthesis of gingerol (chemical present in ginger)?

    • @00bean00
      @00bean00 2 года назад +1

      yes, gingerol is immensely important

  • @Chito5MS
    @Chito5MS 3 года назад +1

    Based synthesis

    • @ChemNews
      @ChemNews 2 года назад

      Hi, perhaps you will like my channel about recent chemistry publications. Just released a video about the recent work of Benjamin List (the guy with the 2021 Nobel prize) hruclips.net/video/ELy3uR9Bsm4/видео.html

  • @keithkeiser9678
    @keithkeiser9678 3 года назад

    Brilliant.

    • @ChemNews
      @ChemNews 2 года назад

      Hi, perhaps you will like my channel about recent chemistry publications. Just released a video about the recent work of Benjamin List (the guy with the 2021 Nobel prize) hruclips.net/video/ELy3uR9Bsm4/видео.html

  • @NightLightnight
    @NightLightnight 3 года назад

    really nice vid!!

    • @ChemNews
      @ChemNews 2 года назад

      Hi, perhaps you will like my channel about recent chemistry publications. Just released a video about the recent work of Benjamin List (the guy with the 2021 Nobel prize) hruclips.net/video/ELy3uR9Bsm4/видео.html

    • @NightLightnight
      @NightLightnight 2 года назад +1

      @@ChemNews lol okay I'll check that out in a bit

    • @NightLightnight
      @NightLightnight 2 года назад +1

      @@ChemNews also I suggest I not comment on everyone's comment or RUclips might think u r spamming

    • @ChemNews
      @ChemNews 2 года назад +1

      @@NightLightnight If you change the text a little bit - youtube does not mind :)
      Unfortunately, there are not too many ways to get new subscribers in the initial stages of the channel...

  • @dzhangarbadmaev1057
    @dzhangarbadmaev1057 Месяц назад +1

    I think I am 3 years late to the party, but the Pd-catalyzed carboxymethylation should have CO instead of CO2 as one of the reagents.

  • @javiermiguelez4656
    @javiermiguelez4656 3 года назад +1

    How do you explain the regioselectivity reduction of the ester in presence of a ketone using LAH ? In my understanding LAH should reduce a ketone very easily 17:50 min

    • @totalsynthesis
      @totalsynthesis  3 года назад +3

      I think it’s just sterics - even though “the bottom” face looks open, the attack trajectory of nucleophiles would be quite shielded by the bulky acetal group. So the ester gets reduced first. The authors didn’t comment on this - but I wouldn’t be surprised if they saw some reduction, especially at more forcing conditions

    • @ChemNews
      @ChemNews 2 года назад

      Hi, perhaps you will like my channel about recent chemistry publications. Just released a video about the recent work of Benjamin List (the guy with the 2021 Nobel prize) ruclips.net/user/ChemNewsvideos

  • @kid_missive
    @kid_missive 10 месяцев назад +1

    So did it cure cancer? I think this would be pertinent info.

  • @doit9854
    @doit9854 Год назад +2

    If I had a penny for each word I didn't understand, I'd be able to open copper foundry.

    • @totalsynthesis
      @totalsynthesis  Год назад +1

      Here's a penny for watching the video regardless 🪙

    • @doit9854
      @doit9854 Год назад

      @@totalsynthesis what class. & anyone who says "melting pennies is illegal" is just volunteering to be your lab assistant/slaves.

  • @Itsadrianyay
    @Itsadrianyay Год назад

    whats the thing at the beginning that says not this maybe later?

  • @ralaksostrov5448
    @ralaksostrov5448 3 года назад

    Please make video about ONC (octanitrocubane) synthesis

    • @ChemNews
      @ChemNews 2 года назад

      Hi, perhaps you will like my channel about recent chemistry publications. Just released a video about the recent work of Benjamin List (the guy with the 2021 Nobel prize) hruclips.net/video/ELy3uR9Bsm4/видео.html

  • @mightyrush3937
    @mightyrush3937 Год назад +1

    8:45 would this not be 1,3-butadiene?

  • @javiermiguelez4656
    @javiermiguelez4656 3 года назад

    Niduterpenoid A seems very complicated molecule as well, do you think we will see soon it’s total synthesis? Congratulations for your Chanel, this kind of contents are not so common in youtube

    • @totalsynthesis
      @totalsynthesis  3 года назад

      Definitely looks interesting!
      Thank you!!

    • @ChemNews
      @ChemNews 2 года назад

      Hi, perhaps you will like my channel about recent chemistry publications. Just released a video about the recent work of Benjamin List (the guy with the 2021 Nobel prize) hruclips.net/video/ELy3uR9Bsm4/видео.html

  • @MarkRLeach
    @MarkRLeach 3 года назад

    Thanks for that, very clear. However, I expect it will be more complicated on a second viewing!

    • @ChemNews
      @ChemNews 2 года назад

      Hi, perhaps you will like my channel about recent chemistry publications. Just released a video about the recent work of Benjamin List (the guy with the 2021 Nobel prize) ruclips.net/user/ChemNewsvideos

  • @haritzheng
    @haritzheng Год назад +1

    Am I a bad viewer for using your video to cope with my insomnia? 😂😂😂

  • @modeidraorossman5273
    @modeidraorossman5273 2 года назад

    Hello!
    Very interesting video. Tell me, you can meet a trotofan bromination reaction or tripartamine bromom in a 5th position. And then in the Russian-speaking literature such a technique to find a gentle. I really know English very badly and I find it difficult to search for such a technique.

    • @totalsynthesis
      @totalsynthesis  2 года назад

      Do you have access to reaxys? This database shows different ways to prepare chemicals
      Are you talking about direct 5-bromination of tryptophan? Not sure if that is possible, you probably need multiple reactions via the 5 bromoindole or others

    • @modeidraorossman5273
      @modeidraorossman5273 2 года назад

      @@totalsynthesis I'm from Ukraine. I am a little difficult to speak English.
      I do not have access to REAXYS. Give a reference to Reaxys. For me, very interesting foreign works of chemists. Maybe I find something for myself.

  • @MichelleHell
    @MichelleHell 3 года назад

    This is why I did bad in orgo. Just seeing synthesis after synthesis frustrated me because I need to understand why each step behaves the way it does and they all have some crazy explanation I'm always either skeptical of or don't understand. And then on the tests all my synthesis proposals are wrong. Each step could take hours to days, and your yield is going to be tiny. 26 steps must have taken months.

    • @ChemNews
      @ChemNews 2 года назад

      Hi, perhaps you will like my channel about recent chemistry publications. Just released a video about the recent work of Benjamin List (the guy with the 2021 Nobel prize) hruclips.net/video/ELy3uR9Bsm4/видео.html

  • @jesusbauer4074
    @jesusbauer4074 3 года назад

    more videos plz

    • @ChemNews
      @ChemNews 2 года назад +1

      Hi, perhaps you will like my channel about recent chemistry publications. Just released a video about the recent work of Benjamin List (the guy with the 2021 Nobel prize) hruclips.net/video/ELy3uR9Bsm4/видео.html

    • @jesusbauer4074
      @jesusbauer4074 2 года назад +1

      @@ChemNews thank u so much for you work, i apreciate it .

  • @yevheniisokolenko5482
    @yevheniisokolenko5482 3 года назад

    by Gaich Group.

    • @ChemNews
      @ChemNews 2 года назад

      Hi, perhaps you will like my channel about recent chemistry publications. Just released a video about the recent work of Benjamin List (the guy with the 2021 Nobel prize) hruclips.net/video/ELy3uR9Bsm4/видео.html

  • @jaykemm3472
    @jaykemm3472 Год назад +1

    I can make a pitcher of kool aid all by myself.

  • @everythingexplained3226
    @everythingexplained3226 Год назад +1

    here's a comment for the algo

  • @MultiAXEeffect
    @MultiAXEeffect 3 года назад +1

    Penguinone

    • @ChemNews
      @ChemNews 2 года назад

      Hi, perhaps you will like my channel about recent chemistry publications. Just released a video about the recent work of Benjamin List (the guy with the 2021 Nobel prize) hruclips.net/video/ELy3uR9Bsm4/видео.html

  • @yourfuneral
    @yourfuneral 3 года назад

    Danke für das interessante video!
    In der Tonaufnahme ist viel Hall, vllt kann man das günstig mit Isolation an der Wand verbessern (Schaumstoff, Eierkarton; klingt wie ein kleiner Raum bzw. direkt vor einer Wand aufgenommen)