DNA Damage Response
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- Опубликовано: 16 июл 2017
- Illustrated is the power of combined interference with different DNA damage response processes to combat cancer: Homologous recombination, which is selectively deficient in the tumour due to the BRCA defect, and base excision repair of single strand breaks, which is blocked by the administration of PARP inhibitors.
Client:
Dr. Rini de Crom
Dr. Marja Miedema
www.erasmusmc.nl, 2014
www.ddresponse.eu/
Funded by the 7th Framework Programme of the European Commission in the theme Health.
More videos from DEMCON Nymus 3D on:
www.demcon-nymus3d.nl 
Кино
![Jason Aldean - Should've Been A Cowboy [Toby Keith Tribute] (Live from the 59th ACM Awards)](http://i.ytimg.com/vi/-B4nR-CgMVA/mqdefault.jpg)
Thank to all those doctors and scientists that enable us to understand our complex body and also saved millions of peoples.
doctors dont discover diseases or find their cures, scientists do
@@theeditor1072what for?
@@artemack9358 to give us brain and all knowledge
I hate those scientists because now as students we need to study all of it. How tf did they discover these anyway. They should had just focussed on politics to save people instead.
@@Rikka_V1 you should be 9
I love how you can explain such difficult to comprehend topic to people with 0 health knowledge by using animations , if I had to learn it from book or just text I would waste hours trying to picture 🖼️ the movements in cells
Yeah and it just randomly evolved, just like Smart Phones.
Yes fr
@@outofthebox9699 Ahhh right and we also just randomly found dinosaur bones that the same science that made this video also tells us is millions of years old, not to mention various shaped skulls dating back hundreds of thousands of years. You can't pick and choose which parts of science you believe
@@derickd6150Get lost sick punk, ur brain is too dumb to understand what I said.
@@outofthebox9699 ur stupidity just randomly evolved like a byproduct of nature u clown
God bless all doctors, nurses and good scientists
I love how you said "good scientists".
Good doctors, good nurses
Plenty of bad medical professionals about this planet at this present time, who will never be forgiven for what they have done.
@@as_if before good doctors and good nurses
You should say good scientist than say doctors and nurses
Scientist test science before doctors than doctors apply that tested science on patients
Big salute to scientists who pulled humanity from pandemic
Good teachers are also in the line of blessing🙌
As a biology student I can say this is amazing.
Yeah and it just randomly evolved, just like Smart Phones.
I hate that I can understand in RUclips, but not in class😅
@@outofthebox9699 sound as logical as god allowing marriage between a 6 year old and a 54 year old 🤡
As a maths students this amazed me also
@@outofthebox9699 Yes, through billions of years of trial and error.
0:50 homologous recombination repair... the solution is just jaw-dropping
It's also essential in CRISPR cas9 editing
Chlorine Dioxide pulls away the ELECTRONS from the Cancer cells. No harmful effects to body parts. This is the hidden cure for all types of Cancers.
@@indiabiologyexplains5013 One question, with CRISP you can change your hair from curly to straight.
Indeed, God is the best of creators.. We’re not even aware all these things are going on in our bodies
@@3alaiyer if you want more cure details send me you e-mail address.
As an engineer student I find it absolutely mesmerizing
The human body never fails to impress me learning through animations like this
SHOW YOUR HUMAN BODY 🔥🔥🔥🔥🔥🔥🔥🔥🔥🔥🔥🔥🔥🔥🔥🔥🔥🔥🔥🔥V
This is all we need...well done!! Even non medical or bio student/person can understand these easily
men get cancer too. sheesh.
My mother, grandmother and sister all have this gene mutation. I may in fact have it. It is incredible to know what happened now. It is hard to believe how much progress has been made in the past 50 years.
The only thing hard here is your stupid brain
ruclips.net/video/SwNX2gSbgso/видео.html
I just love how to make it easy and explain each and everything (it's causes and treatment)
Everytime I see this sort of video, I feel like continuity of my existence as a lifeform itself is some kind of miracle and I could die any second in afterward
This would have made high school biology class so much easier to understand.
Hopefully this type of learning helps further our understanding of these conplex topics. Visual learning is crucial for so many people.
Our body is so fascinating . Respect for my body is increased after this video ♥️🔥
Not for the Maker?
@@tphone6717 don't exist...(wait are u talking about parents?)
@@_emminowithoutl4995 you have a surprise waiting
Yeah and it just randomly evolved, just like Smart Phones.
@@_emminowithoutl4995 what about the ultimate maker ( also of our parents )
People dont realize that DNA is language of the Gods.
Not a biology student but understood what these people explained.
no you didn't, FOOL
@@alexshapiro9841 LMAO DED.
@@alexshapiro9841 ruclips.net/video/RYDy_nlgi5Q/видео.html
@@alexshapiro9841 Stop gatekeeping
@@alexshapiro9841what is hard of getting it? If DNA isn't getting repaired cell becoming a cancel cell.
All of this technological advancement, and my mom still died after being given the same treatment that they've been giving patients for fifty years. We need to push treatments like this to more people who need them and make them more wildly available.
A todo el mundo
😢
I bear witness that there is no god but God, alone without partner.. Glory be to God and praise be to Him
Tottaly stupid comment on a scientific video.
Understanding biology by animation is genius
you aall are so good at ur JOBS damn !!! May God bless you and reward you for your work . stay safe .
Simply Beautiful in every aspect, from science to animation.
As a science history and biology student (even though I have more lessons) this is amazing.
Our bodies are amazing!
Man the animation is so sick and beautiful. Thank you very much.
Bro tysm for making this video. I'm going to be writing a literature review on PARPi and BRCA1 cancers so this video helped explain everything in a very simple way
Bro why do you have only 11k subs you deserve 11 million.🥺
thankyou for being so much better than several other explaining this
You are so welcome! We do our best! :)
The animation and explanation made it easy to understand, great vid 👍
I can't explain how useful these video are for me to understand this complex theory. thanks, million times!
Thank you so much for your work! Love it!
Absolutely fascinating!
Thank you for this awesome animation!
Love this video
I'm happy knowing treatment for the deadly cancer.
This is science of next level
that was an amazing show, many thanks for your attempt to prepare it🙏💖
Thank you for that amazing and easy explanation of this ❤️❤️❤️❤️
Thanks for this beautiful explanation 💓
Wow, this is absolutely fascinating.
If this is an ad, it would be the type I would actually watch.
The way of explaining this topic, is just amazing 🌼
Extremely clear and understandable. Thank you
These calm me down for some reason and so do "How It's Made" vids.
This is really impressive, and as a biology student I now understand the diseases that might affect cells of DNA and the prevention process.
This is amazing! Props to the animators. Amazing explanation
I loved the way of her explanation by 3D demantions
Very informative..learning in innovative way..really explained well in best ever experience..commendable and appreciable!!
does anyone else find these things so fascinating? to me it feels like a fairy tale where everything just works out perfectly
Not all the time. People are constantly dying of cancer.
Brilliant video, awe inspiring.
Thanks so much!
@@Nymus3D do they have a copy of the dna from the PCR or they just copy whatever was damaged from the dna?
@@Nymus3D thank you so much for making this veidio ❤❤❤
ruclips.net/user/shortscD7vOkhYZpA?feature=share
Thank you
Most helpful video 👌🏼👌🏼👌🏼
Such designs so complicated and seem to be moving on its own with such delicate and amazing feats yet humans concludes that this is the result of random elements and dust clustering on its own with the help of time, lightning, heat and light is enough to produce such intricate work of arts.
I was actually busy studying on this EXACT subject for biology, so I appreciate this video *
Please put such videos in a playlist.
Perfect!! God bless you
Thank you Anwar!
@Imperial Terra it is just figure of speech, I dont believe in god either
@@autismunion lol
@@autismunion me neither brother
Nutso.
Thank you for not dumbing it down
That explanation is really great🥰
Now I come to know that how breast cancer arises and repaired you have explained very well
stellar graphics!
really helpful!!! better than textbooks
Amazing how the body works.
Sounds AMAZING
How amazingly we were designed.
We were not designed, don't be foolish.
@@gibbogle Anyone who knows anything about the function of biochemistry, and believes that it all just created itself without a designing mind, believes in magic and has blind faith in the religion of materialism. Life were obviously designed.
@@Hannodb1961 If anything is magic your god is. I do know a bit about biochemistry. Evolution is hard to understand, but supernatural non-material entities are impossible.
Very well explained easy to understand Thank you .
Wow this explained it better than my medical school
Beautiful animation...
thank you for this information
The only thing more insane than the complex specificity of cellular biology is that we are able to, from our human scale, be that specific down there in the micro world.
This is amazing
Thank you for video I am student of nurse and these video animations help me of lot🙌
The graphics are amazing 😮
Thats amazing how our bodies work like this
How great Thou art, indeed Heavenly Father❤❤❤❤❤❤
Fascinating!
Excellent video.
It's super amazing to understand the concept of biology ♥️❤️🥺❤️
I love it what ur going to explain how magic is this i didn't understand this magic when I am in class
Underrated channel 😔
Truly magical
Although it is not that simple as stated in the video, I loved the animation and narration.
Ofc it's not that simple we're talking about biology here. That said, this is a very good summary of what happens and proves a great foundation for people to learn more if they want to
amazing ! , thanks :-)
This is all amazing but how these proteins know that’s there job to repair DNA is amazing to me. How the is a subtle chemical process that causes this specific action is amazing. DNA is a wonder.
Glory be to God, the best of creators ✨
Fantastic, that's awesome.
Thank you 🙏
Really just awesome❤
Another lesson we can benefit
I can't help but think that explanation is missing a crucial part. It says some patients lacking double strand break repair functionality due to their inheritance is what causes the cancer, but then proceeds to state that the ability to repair double strand breaks is what prevents all the non-cancer cells from dying as well.
Without additional information, those two statements feel a bit contradictory to each other: An issue caused by the inherited lack of an ability is fixed based on trusting in the very same ability the lack of which caused the issue, and killing anything with a lack of that ability.
We should all be amazed and revere our bodies.
Grt video during study I always use to assume that how these DNA break and repair through this animation now I understood that. 😁😘
These organisms are living quite an interesting life!
Background music.. exited..❤️
Thank you very much
easily 10 hours' worth of grad-school medical knowledge explained in under 4 mins
The human body fascinates me ❤
Extraordinary
Excellent voice🇮🇳 👍
and music 👍
Thank for information
Amazing
POV: you're the first to fall asleep at a sleepover (rookie mistake)
Best video 🙏
Just recently this february my sister in-law passed away due to this cancer...we have done everything the doctors tell us bit nothing happy it became more disastrous ,So painful and heartbreaking for her kids who still baby.😭😭😭😭😭
Well explained
Thx for easy technology method 🙏
Damn that's amazing 😮
You cannot tell me this is not designed by an incredible mind. The work of God is clearly seen here in the various DNA repair systems.