The problem with the Rhogam shots is that they carry severe and deadly adverse events - Intravascular hemolysis (IVH) leading to death has been reported in patients treated for immune thrombocytopenic purpura (ITP) with Rho(D) immune globulin. IVH can lead to clinically compromising anemia and multi-system organ failure, including acute respiratory distress syndrome (ARDS), acute renal insufficiency, renal failure, and disseminated intravascular coagulation (DIC). Alert patients and closely monitor for the signs and symptoms of IVH in a health care setting for at least 8 hours after administration for ITP. Perform a dipstick urinalysis at baseline, 2 hours, 4 hours after administration, and prior to the end of the monitoring period. If signs and/or symptoms of IVH are present or suspected, post-treatment laboratory tests should be performed. Hemolytic reaction includes hypotension, nausea, chills, headache, and a decrease in haptoglobin and hemoglobin. Disseminated intravascular coagulation, Intravascular hemolysis, hemolysis resulting in death, clinically compromising anemia, extravascular hemolysis, hemolytic reaction, etc.
THANK YOU!!!! The medical perspective always tells us the benefits of the intervention and the risks of not doing the intervention. Rarely is it shared the risks of the interventions! And that’s how true informed medical consent is given, only after we have an understanding of the risks vs the benefits of ALL ASPECTS!
My story- Mom (me), age 28. after trying to get pregnant for just a few months, she misses her period. After 3 weeks, she has a really heavy period. Was this an early miscarriage? We will never know for sure, but all signs indicate that it was. In the very next month after her super heavy period, her period is again late. Two more weeks go by and she decides to get a pregnancy test, and wahoo, she’s pregs!!! Great news! So she goes to the ob/gynie doc, who shifts from gynie to ob mode in 2 seconds flat, pronounces her 6 weeks pregnant, noting that “You are Rh negative so we will be giving you Rhogam at 27 weeks.” Wow, I never knew about this Rh disease thing before…in fact, I never knew I was Rh negative, for that matter.” Okay, Rhogam! Super! (Completely and utterly oblivious to the dangerous situation already brewing, deep within her womb). There’s more to the story……see comment 2!
Comment 3, the story continues! Well, you probably guessed it. When Mom’s (me/my) blood was tested, elevated levels of certain kind of antibodies were detected. She was “sensitized!” Most likely during the assumed early early miscarriage, 1 month before becoming pregnant with Embryo Emily, as in Emily Beach. Because the new pregnancy had happened so soon after the earlier early miscarriage, not enough antibodies had even had a chance to develop, by the time moms blood was first tested. So no antigen, or “D” (?) could be detected. No antibodies (plotting their vicious attack) could be found in the mother’s blood, so no risk to Embryo Emily was presumed. Little did anyone know that in actuality, Mom’s body was already building enough antibodies to begin attacking the blood of Embryo Emily, long before the Rhogam, that lifesaving human plasma product, that in this case, was fully obsolete. Stay tuned to find out the fate of Embryo Emily ( hint….she does undergo a name change at around 12 or 14 weeks)…..see comment 4
Comment 2, the story continues……… Well, the pregnancy continued with no problems for the next 21 weeks. As planned, the Rhogam was administered at 27 weeks, to prevent that Rh+Rh- crossover, or “sensitization”, or, you know, that thing that happens, from happening. The pregnancy continues and all is well. After 20 hrs of labor, the birth is an unplanned cesarean, due to the breech position of the fetus. The baby (hereafter known as Emily Beach, or Baby Girl Beach,”) has significant hip dysplasia necessitating several months in a harness. More concerning is this: by day 2, BGB is also quite jaundiced. Placed under bili lights and blood tested every 6 hours.-after the abnormally high levels of bilirubin was found, another blood test was ordered, this time on mom (me), because…….hmmm, this mom is Rh negative. Uh oh, why is this baby so jaundiced? But she had Rhogam!! Can’t stand the suspense? See comment 3 to read the next, riveting chapter of the story!
Maternal Newborn Playlist: ruclips.net/p/PLhad3zgh1HIbNLyJtcpVMoKS0S-rRBrfI
This is so good 😍just like my friend explaining the syllabus just before exam
You should be in recommended list of RUclips. Thank you for this.
The problem with the Rhogam shots is that they carry severe and deadly adverse events - Intravascular hemolysis (IVH) leading to death has been reported in patients treated for immune thrombocytopenic purpura (ITP) with Rho(D) immune globulin. IVH can lead to clinically compromising anemia and multi-system organ failure, including acute respiratory distress syndrome (ARDS), acute renal insufficiency, renal failure, and disseminated intravascular coagulation (DIC). Alert patients and closely monitor for the signs and symptoms of IVH in a health care setting for at least 8 hours after administration for ITP. Perform a dipstick urinalysis at baseline, 2 hours, 4 hours after administration, and prior to the end of the monitoring period. If signs and/or symptoms of IVH are present or suspected, post-treatment laboratory tests should be performed. Hemolytic reaction includes hypotension, nausea, chills, headache, and a decrease in haptoglobin and hemoglobin. Disseminated intravascular coagulation, Intravascular hemolysis, hemolysis resulting in death, clinically compromising anemia, extravascular hemolysis, hemolytic reaction, etc.
THANK YOU!!!! The medical perspective always tells us the benefits of the intervention and the risks of not doing the intervention. Rarely is it shared the risks of the interventions! And that’s how true informed medical consent is given, only after we have an understanding of the risks vs the benefits of ALL ASPECTS!
This is great and simple. My professor always made it so confusing
Blessed you !
These are pretty great videos. Very helpful! Thanks for the quick lesson and recap!
This video helped me understand this concept so well!!! Thank you!
Hello can you please answer thus q Why is the risk of Rh D alloimmunization after first birth
higher if the fetus is ABO compatible with the mother?
I love your videos 💙
Thank you, explain in very simple ways.
What happens when mother is rh positive and baby is rh negative?
Good teacher thanks 🙏
Excellent...keep it up
My story- Mom (me), age 28. after trying to get pregnant for just a few months, she misses her period. After 3 weeks, she has a really heavy period. Was this an early miscarriage? We will never know for sure, but all signs indicate that it was. In the very next month after her super heavy period, her period is again late. Two more weeks go by and she decides to get a pregnancy test, and wahoo, she’s pregs!!! Great news! So she goes to the ob/gynie doc, who shifts from gynie to ob mode in 2 seconds flat, pronounces her 6 weeks pregnant, noting that “You are Rh negative so we will be giving you Rhogam at 27 weeks.” Wow, I never knew about this Rh disease thing before…in fact, I never knew I was Rh negative, for that matter.” Okay, Rhogam! Super! (Completely and utterly oblivious to the dangerous situation already brewing, deep within her womb). There’s more to the story……see comment 2!
Comment 3, the story continues! Well, you probably guessed it. When Mom’s (me/my) blood was tested, elevated levels of certain kind of antibodies were detected. She was “sensitized!” Most likely during the assumed early early miscarriage, 1 month before becoming pregnant with Embryo Emily, as in Emily Beach. Because the new pregnancy had happened so soon after the earlier early miscarriage, not enough antibodies had even had a chance to develop, by the time moms blood was first tested. So no antigen, or “D” (?) could be detected. No antibodies (plotting their vicious attack) could be found in the mother’s blood, so no risk to Embryo Emily was presumed. Little did anyone know that in actuality, Mom’s body was already building enough antibodies to begin attacking the blood of Embryo Emily, long before the Rhogam, that lifesaving human plasma product, that in this case, was fully obsolete. Stay tuned to find out the fate of Embryo Emily ( hint….she does undergo a name change at around 12 or 14 weeks)…..see comment 4
Comment 2, the story continues………
Well, the pregnancy continued with no problems for the next 21 weeks. As planned, the Rhogam was administered at 27 weeks, to prevent that Rh+Rh- crossover, or “sensitization”, or, you know, that thing that happens, from happening. The pregnancy continues and all is well. After 20 hrs of labor, the birth is an unplanned cesarean, due to the breech position of the fetus. The baby (hereafter known as Emily Beach, or Baby Girl Beach,”) has significant hip dysplasia necessitating several months in a harness. More concerning is this: by day 2, BGB is also quite jaundiced. Placed under bili lights and blood tested every 6 hours.-after the abnormally high levels of bilirubin was found, another blood test was ordered, this time on mom (me), because…….hmmm, this mom is Rh negative. Uh oh, why is this baby so jaundiced? But she had Rhogam!! Can’t stand the suspense? See comment 3 to read the next, riveting chapter of the story!
Stay tuned…….
suspense... thank you for sharing your story
Dang u r smart, girl!
So male can be RH- , female RH+ no problem w/ their kids?
It only matters if the woman is RH -
This is osmm....
So wait, do you have to get it at 27 weeks pregnant if you got it right after miscarriage?
This is the standard time to get it and after anything causing bleeding.
3:34 " all of my students"
Really? You look like 20 😂
Thank you! :)