This Is The First Exercise PILL, And It’s Unbelievable

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  • Опубликовано: 2 ноя 2022
  • Would you take an exercise or weight loss pill if it meant you could get all the benefits without even moving?
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    Written by: Mitchell Moffit
    Edited by: Luka Šarlija
    SOURCES/FURHTER READING
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Комментарии • 1,8 тыс.

  • @lucasprobably
    @lucasprobably Год назад +586

    I'm disabled and chronically ill, and I can't exercise without permanently worsening my illness, so this kind of research would make a huge difference to me!

    • @iamthemobey
      @iamthemobey Год назад +17

      Stay strong brother 💪

    • @Sepear305
      @Sepear305 Год назад +5

      Yes I hope this becomes available soon! Do u mind me asking what illness you have that damages you if you exercise?

    • @sanderminnee8666
      @sanderminnee8666 Год назад

      Well what do you have in the frist place

    • @MsTwissy
      @MsTwissy Год назад +1

      Same! I wish I could get on the test list. This would be life changing.

    • @dirtysploof5890
      @dirtysploof5890 Год назад +14

      @@sanderminnee8666 none of your damn business lol

  • @samimabii963
    @samimabii963 Год назад +1056

    It's well used in the bodybuilding community. Usually sold under the SARM category even though it isn't a SARM.
    You can feel the endurance improvements right away. It honestly feels like magic. I stopped using it as it felt too good to be safe
    It's also known under the name "Cardarine". They stopped most research on it because of one incident where it's use indicated increased cancer growth in rats

    • @culturebreath369
      @culturebreath369 Год назад +139

      Always some cancer with stuff like this..

    • @atrum2355
      @atrum2355 Год назад +113

      @@culturebreath369 that study was very flawed.. Bc of that study nobody continues to make new studies about it… perhaps we’re missing out…..

    • @env0x
      @env0x Год назад +38

      I mean, what doesn't cause cancer?

    • @augustuslunasol10thapostle
      @augustuslunasol10thapostle Год назад +1

      @@env0x literally nothing everything has a chance to cause cancer even the cleanest types of air

    • @dxcSOUL
      @dxcSOUL Год назад +43

      @@env0x water

  • @crispyhoneybun1607
    @crispyhoneybun1607 Год назад +79

    I have chronic excuses that keeps me from exercising.
    This would be life changing for me.

  • @patdaubert8614
    @patdaubert8614 Год назад +2187

    This would literally change my life. I have chronic illness that makes exercise way more difficult for me. Lots of basic movements actually harm my body so a pill like this could be huge for me. I hope we get this out in the public soon enough

    • @lightishredroses
      @lightishredroses Год назад +115

      Not excuses, I also have a chronic illness that causes me physical agony if I move a lot most days. This would also change my life on so many levels

    • @dhruvagarwal
      @dhruvagarwal Год назад +147

      @@5gun1 ye call a person w some cvs or rs disease whos is physically unable to do it as an excuse, pray that one day you dont end up on the other side

    • @One_Sun_One_People
      @One_Sun_One_People Год назад +45

      @@5gun1 ignoramus

    • @Jlewismedia
      @Jlewismedia Год назад +5

      @@5gun1 based

    • @Sunscreen723
      @Sunscreen723 Год назад +21

      Lol, excuses ,stop being lazy

  • @onemoreweirdo207
    @onemoreweirdo207 Год назад +748

    That seems like a great thing to help people (and animals) who need this, however I really hope we don't mess it up.

    • @kjuds4169
      @kjuds4169 Год назад

      It's marketed as cardarine, it's an illegal ped and causes cancer.

    • @godricktheminecrafted3113
      @godricktheminecrafted3113 Год назад +39

      You know someone’s going to patent it and sell it for 6 million per pill

    • @erdemalegoz1816
      @erdemalegoz1816 Год назад +11

      We already messed up mate don't you worry.

    • @AndrewPonti
      @AndrewPonti Год назад +4

      Exactly what I was thinking - a la the "V" drug from "The Boys"

    • @giovannamoro8564
      @giovannamoro8564 Год назад +2

      We will for sure as usual

  • @try-athlete
    @try-athlete Год назад +1017

    *A pharmacist has entered the chat* GW501516 is called cardarine (sometimes also called endurobol) it was developed sometime in the 90's by GSK but then dropped before it was brought to market. It's become fairly popular in the fitness industry in the last few years. One of the biggest benefits I've seen on paper and anecdotally is the increase in HDL (high-density lipoproteins) which are generally considered cardioprotective. I'll also mention that the doses of Cardarine that were given to mice that increased cancer risk were astronomically high and far above the minimum effective dose. That study was most likely establishing the maximum tolerated dose which is a very standard practice in drug development and design prior to human studies because you don't want to put a lot of money into developing a drug that is going to kill people and/or get you sued for causing cancer.
    This drug is no magic pill though and while it does seem to be very effective and the side effect profile very low it probably won't be brought to market for just those reasons. Treating chronic disease is a huge market and currently the money is in the treatment not the cure unfortunately. Couple that with the fact that at this point it is fairly easy to obtain cardarine online already any company that wanted to patent it or a similar version would probably not make much money.
    If you are interested in how Cardarine works Ryan Russo has a pretty in-depth analysis of it on his channel.
    I haven't heard of compound 14 before unless it goes by another name but the way it works sounds similar to glucose disposal agents which are also pretty widely available now. It also seems slightly similar to DNP (2,4-Dinitrophenol) which is a very toxic drug used to lose weight so hopefully that's not what it is.

    • @jemmerllast8492
      @jemmerllast8492 Год назад +102

      I looked this up and found that the moment they dropped the ID name. This video seems very under-researched and even misinformative :/

    • @jrodax5468
      @jrodax5468 Год назад +43

      This comment should be at the top

    • @theodora_pilates
      @theodora_pilates Год назад +11

      Your comment and the video you mentioned were very useful, thank you!

    • @try-athlete
      @try-athlete Год назад +4

      @@theodora_pilates you're welcome!

    • @brandiminor1632
      @brandiminor1632 Год назад +7

      Ok, you're my hero. Thank you. Can you recommend a brand for the cardarine?

  • @monicatoro2286
    @monicatoro2286 Год назад +45

    Hey guys! I think I saw you two days ago in my city, Medellin, Colombia, and I was so surprised of seeing you here that I just got super nervous and couldn’t go and tell you how much I admire you! I hope if it was actually you that you enjoyed my city and had a great time. Hugs!!

    • @gsesini1621
      @gsesini1621 Год назад +1

      I bet he had a great time. Who doesnt love Medellin?

  • @shimasclan
    @shimasclan Год назад +136

    I would love it as a booster. The worst part of getting into shape again is getting the initial activity and fat burn going. I know once I've been at it for a month or two, it will be easier, but starting is rough. If I could loose weight quicker at the start, it would be a strong motivator.

    • @shloimycapland8491
      @shloimycapland8491 Год назад +13

      I'd actually recommend the opposite, since it's already easier to lose weight in the beginning don't take it first and then take it when weight loss gets tougher

    • @Juggernaut-fg2up
      @Juggernaut-fg2up Год назад +9

      Pure laziness

    • @Spookatz.
      @Spookatz. Год назад +5

      @@Juggernaut-fg2up i think it's fine to use what's at your disposal to help stay healthy

    • @shimasclan
      @shimasclan Год назад +4

      @@Juggernaut-fg2up if that's your opinion. It's the start that can be the hardest part cause your body isn't used to the activity. I'd say 'lazy' is a better descriptor for someone who stops trying completely after a couple weeks.

    • @Juggernaut-fg2up
      @Juggernaut-fg2up Год назад +6

      @@shimasclan you just ease into it, you start off super simple and low intensity. Even if it's sitting in a chair and just raising your arms and legs there's a way to do it I promise you. I have trained thousands of people over my lifetime, I specialize in injury Rehabilitation it have worked with some very injured and sick people. All drugs have side effects including this one. It's predecessors have been shown to have very bad long-term side effects. This is what it says about this one..."Cardarine may be a potential carcinogen and its effect on humans has not been systematically investigated."

  • @pasi123567
    @pasi123567 Год назад +393

    I don't think you can imitate all the benefits exercising has by just taking certain pills, since the movement in itself I believe gives a lot of benefits. But if there will be a pill that can do some things that can be achieved with exercise for people who aren't able to, then certainly this could be a good alternative.

    • @seymur7422
      @seymur7422 Год назад +11

      You dont know PEDS, it's scary how efficient they are

    • @1005corvuscorax
      @1005corvuscorax Год назад +3

      @@seymur7422 not to mention some of the side effects, depending on the PED in question.

    • @TurdFurgeson571
      @TurdFurgeson571 Год назад +15

      Why couldn't we imitate exercise? There isn't anything special about the physical process of doing exercise. It's just our roundabout way of triggering the production of useful chemicals. If we want to lose or maintain weight, for example, we need to physically exercise because byproducts of energy _use_ (exercising) have this effect. We want the byproducts of the energy use process. As of now, the only way we know how to get those byproducts is through exercise. And also, as someone else mentioned, a rudimentary approach is performance enhancing drugs (PEDS).
      Side note: I think such an "exercise pill" is still well in the realm of science fiction, but like any good sci fi, it's not theoretically impossible.

    • @seymur7422
      @seymur7422 Год назад +4

      @@TurdFurgeson571 it's because we really don't understand it enough to "synthesise" it.

    • @seymur7422
      @seymur7422 Год назад +4

      @@1005corvuscorax after all the mice ended up developing cancer

  • @khalilahd.
    @khalilahd. Год назад +1834

    I think this is great invention for people who are unable to workout however I hope this doesn’t become wide spread as a substitute for working out. That’s just going to breed a whole bunch of problems 😅

    • @LudenB
      @LudenB Год назад +59

      How you know that?

    • @axisaligned9799
      @axisaligned9799 Год назад

      @@LudenB they just making shit up because they don’t understand the science

    • @stuntenmetstorm
      @stuntenmetstorm Год назад +47

      perfectly summarised my thoughts

    • @peep113
      @peep113 Год назад +47

      amazing invention, but then you hear the side effects of it... 😬of course

    • @thesylvan
      @thesylvan Год назад +119

      I am morbidly obese and have worked hard to lose weight. I have lost 107 pounds but still have more to lose, but my extreme weight has damaged my knees and heart, so a lot of activities are difficult or impossible for me. If this pill works, I could get to a healthy weight and do more exercise- I miss the activities of my youth- hiking, climbing, rafting, etc. and would love to get back to those activities.

  • @DarthProlif
    @DarthProlif Год назад +33

    I lift, and the major thing about lifting isnt the end game, its about the journey. I personally wouldnt take the pill, but its nice to see being an option for those who would need it. Cant expect someone over 400lbs to just start exercising without major obstacles

    • @desmondhui5449
      @desmondhui5449 Год назад +2

      If it’s safe I would personally love to take it while continuing my normal lifting just to see how quickly the gains can occur. Alas I will stick to my normal regiment for now

  • @kyssedbyfyre915
    @kyssedbyfyre915 Год назад +10

    I'm a former body building enthusiast and self proclaimed workout addict. A not-at-fault auto accident in 2010 left me disabled and in chronic intractable pain. I developed fibromyalgia and CFS. I DREAM of and still fight for a higher degree of mobility, not because I am able, but because I can actually FEEL my body dying from this sedentary lifestyle I've been forced to live. Night and day from who I was before. Depression, suicidal dips just trying to deal with so much pain and loss of enjoyment of life. Then add weight problems to the mix due to inactivity 🥺 that's where MANY chronic pain/chronic illness patients exist. Medicines like this would benefit our lives in ways we have only dreamt of! I hope they can roll out something affordable and attainable for those who need it most.

    • @echomatusik5060
      @echomatusik5060 Год назад

      i have cfs and fibromyalgia too but I'm only 14 so i miss out on so much of the physical activity that i should be doing even in pe class. i really really hope that a medicine like this becomes accessible for people like us because it would genuinely make my life 100 times better

  • @andyhaochizhang
    @andyhaochizhang Год назад +14

    One minor correction, the "recommended 150min" is really the recommended minimum. There's strong evidence suggesting more than 150min is better, but 150min is sufficient to confer enough benefit. To say "recommended" can give the false impression that 150min is the optimal amount.

    • @rwnmrr
      @rwnmrr Год назад

      I immediately understood that "recommended 150 minutes" meant minimum. language is quite ambiguous, so I wouldn't say they were wrong, just could have been a bit clearer.

  • @gionmattiacarancini3578
    @gionmattiacarancini3578 Год назад +442

    This is really interesting...people with severe obesity could take this drug as a last resort to burn fat fast. That could help to reduce their weight and as a positive reinforcement towards being more active, since they can see the effects of their training sooner

    • @dirtysploof5890
      @dirtysploof5890 Год назад +77

      we already have meth, brother

    • @brack799
      @brack799 Год назад +24

      @@dirtysploof5890 💀

    • @prodnyu
      @prodnyu Год назад +10

      @@dirtysploof5890 🤣🤣🤣🤣

    • @duskshadow25
      @duskshadow25 Год назад

      The number one reason for obesity is because of their diet. Nearly everywhere you go, all the garbage food Americans eat are always high in sodium and high in sugar and greasy as hell. Everything is supersized to the point where they want you to consume more so you can become obese. It's just so bad. And people don't like to eat vegetables a lot of time because they don't know how to cook properly, as it's always either boiled or steamed peas or some crap. I wouldn't want to eat that either.

    • @just_some_donkus
      @just_some_donkus Год назад +1

      love this!

  • @BastionMarshall
    @BastionMarshall Год назад +69

    As someone with severe ME, I would be very interested in something like this (once it's gone through the necessary testing). Exercising isn't an option for me as even light physical activity can cause a crash.
    I do worry about it being pushed as an alternative to exercise because the weight loss industry is predatory.

    • @Pimkly
      @Pimkly Год назад +4

      I was just thinking thinking the same! It would be awesome for ME as a treatment to be able to regain back your life and then at some point, being able to exercise on your own!

    • @leilv2555
      @leilv2555 Год назад

      Try Wegovy if you intend to lose weight. It works and FDA approved, not like Other no evidence Products. Building muscle I don’t know there is a product would that .

    • @Sepear305
      @Sepear305 Год назад

      What is ME if you dont mind me asking?

    • @jjsunshine
      @jjsunshine Год назад

      @@Sepear305 Myalgic Encephalomyelitis .... most people are more familiar with the name Chronic Fatigue Syndrome but that name is used less nowadays because it trivializes the symptoms. When people with ME are tested using CPET for no more than 10 min on two consecutive days, their stats are HUGELY worse on the second day. This effect is unexpected by specialists who find that even sedentary or people with depression or MS usually stay the same or better on the second day.

    • @Sepear305
      @Sepear305 Год назад +1

      @@jjsunshine Oh I see, that's interesting. Thanks for telling me. What is CPET though?

  • @katieesler7659
    @katieesler7659 Год назад +87

    I feel like this would be so helpful with those that struggle with mental illness as well! So much research to say research helps MH but if you’re so depressed , you can’t get out of bed this could help at least initially I imagine!!

    • @RikkerdHZ
      @RikkerdHZ Год назад +7

      Again, humans always resorting to pills.. Why not stimulate developing discipline, regular exercise, healthy diet and meditation/cold exposure? Noooooo, that's way too much work! .....

    • @kathyl9222
      @kathyl9222 Год назад +7

      @@RikkerdHZ ok boomer

    • @bread3156
      @bread3156 Год назад +1

      @@RikkerdHZ 🤝

    • @shlualiab3394
      @shlualiab3394 Год назад +2

      @Kathy L he's not wrong your not disciplined at all

    • @piiinkDeluxe
      @piiinkDeluxe Год назад

      Is not getting out of bed the chicken or the egg?
      Because the impact exercise has on mental health has been proven countless times.
      Just start somewhere. Just go for a walk, maybe only a few minutes. Or, do some easy self care at home, like yoga.
      If you actually stay in bed, you can do things like leg lifts or even just conscious breathing like in shavasana (yoga).
      There are ways to improve. Don't compare yourself and remember progress looks more like 📈 than a straight line. Be nice to yourself.
      Also make sure there are no medical reasons (like thyroid problems) that can make you feel this way.

  • @tarinindell8217
    @tarinindell8217 Год назад +15

    These ideas are amazing, especially for people with various disabilities that make any form of exercise difficult.

  • @Angel-gc4kd
    @Angel-gc4kd Год назад +34

    Personally I don’t think I’m the first candidate for a drug like this, but the idea is still exciting to me. I had a couple traumatic events happen when I was 18 and in the span of about 2 months I gained a substantial amount of weight that has affected other aspects of my health since. I’ve lost most of the weight but our bodies fight weight loss so even though I’ve been trying for a long while the last 20 pounds or so has been the hardest part. I know I wouldn’t cary my extra weight if not for my ptsd spike so something like this would be great to help finally shed my reminder gut.

    • @TBlacky
      @TBlacky Год назад +2

      Don’t recommend. Take an actual study advice.

  • @Fastlan3
    @Fastlan3 Год назад +26

    Hell yeah, bring on the exercise pill! I have worked out most of my life and would enjoy continuing even with the pill. The pill would ensure the benefits are not as easily lost with age, as I have a multitude of conditions making exercise more difficult and less impactful as I get older. I am working more than ever so I have less time. I work long hours that is mostly sedentary. I try and diet well, but eating when and what I want isn't always an option... Also I love delicious foods 😋

    • @WigganNuG
      @WigganNuG Год назад

      Check the comments here; its actually a well known drug that body builders have been using for some time.

  • @manningermani
    @manningermani Год назад +27

    I would take the pill but I wouldn't stop moving. The psychological benefits of challenging yourself and moving out of your comfort zone are equally important for me.

    • @guedrini2045
      @guedrini2045 2 месяца назад

      I have taken cardarine for a cycle and when you start noticing the increased performance and results it significantly increases ur motivation to keep progressing and pushing yourself not to mention what it does for your confidence and mental health but agreed without working out alongside it theres no point. It only works as hard as you do!

  • @enoughalready244
    @enoughalready244 Год назад +219

    I'm so excited for this!! I'm disabled and unable to exercise due to a rare autoimmune disease, and I gained a ton of weight from being on high dose steroids for a year early in my treatment. Even though my Dr stopped the steroids, I haven't been able to get the weight off due to not being able to exercise. And it sucks because the extra weight has caused so many more problems along side my other diagnoses. A pill like this would be freaking AMAZING, and would absolutely improve my quality of life, even just a small amount. Hopefully I'll still be around by the time something like this is approved for public use!!! 🤞

    • @primrose6794
      @primrose6794 Год назад +5

      I've got severe headaches that cause me to fall over when I stand up for too long. I can relate to the inability to exercise.

    • @just.jayshree
      @just.jayshree Год назад +3

      I’m in the EXACT same situation 😭

    • @enoughalready244
      @enoughalready244 Год назад

      @@primrose6794 omg that's awful! Is it some sort of migraine disorder? Do you know why you get them?

    • @enoughalready244
      @enoughalready244 Год назад

      @@just.jayshree as me, or the other commenter? Either way... I'm sorry. Both situations suck BAD

    • @Sunscreen723
      @Sunscreen723 Год назад +1

      Lol haha excuses ,get up ,leave the couch alone and excersise

  • @marclink0
    @marclink0 Год назад +14

    The exercise pill will be a ground-breaking discovery ! However, I believe it will be a trade-off between the benefits and of course the side effects that will indisputably come along with it. As such, it will be thoroughly regulated by physicians and only be prescribed as a short-term solution to help towards better levels of physical activity in populations who can't get there without.
    Also, taking a pill will never bring the social aspect that physical activity has. Working out in a crowd motivates quite a lot of people, like with group classes

    • @seymur7422
      @seymur7422 Год назад +1

      controlling drugs it's harder than it looks like, there's going to be a black market.

  • @mhmgem4199
    @mhmgem4199 Год назад

    I have always enjoyed your videos and vlogs; they are entertaining, but also educational. Thank you!😀

  • @andy6877
    @andy6877 Год назад +5

    as someone with chronic fatigue this could actually revolutionise how we approach recovery - at the moment pretty much all you can do is rest and very very very gradually increase exercise by tiny intervals, but if you push too hard you get a set back and if you don't push enough you also are set further back. A pill that could give the benefits of increased endurance, muscle tone, and weight control without posing the risk of further exhaustion would be life changing for those of us with Chronic fatigue and related conditions like POTs - definitely would be super helpful for chronically ill folks like myself. As it is, I take vasoconstrictor to help increase my blood volume to reduce my heart rate to increase my capacity for exercise quicker, but its still extremely slow and in summer I can barely move at all. If it was proven safe I would absolutely consider medication like this

  • @chikapow93
    @chikapow93 Год назад +8

    Lol that contrast got me:
    First 90% of the video: "Here's a thing that makes you healthy without exercise!"
    Last 10% of the video: "But you get cancer."

    • @cooluser23
      @cooluser23 Год назад +2

      Not to mention that this compound is not new at all. The research was abandoned in 2007.

    • @shmooveyea
      @shmooveyea Год назад +1

      @@cooluser23 All these kinds of compounds violate precautionary principles - the rush to commercialize any of them could easily lead to future class-action lol

    • @cooluser23
      @cooluser23 Год назад

      @@shmooveyea not sure what you mean.

    • @shmooveyea
      @shmooveyea Год назад

      @@cooluser23 Developing a pill to mimic a result of which the metabolic and mechanistic pathways aren't even fully understood = not the greatest idea.

  • @Nuttilicious
    @Nuttilicious Год назад +3

    as someone who has chronic illness and exercised-induced symptoms (asthma attacks and syncope episodes), this would literally change my life

  • @mssmith9227
    @mssmith9227 Год назад

    Fascinating!! Thanks for sharing 👍 😊 😀

  • @EternalBoy333
    @EternalBoy333 Год назад

    Great videos, thanks 🙂

  • @Hex.A.Decimal
    @Hex.A.Decimal Год назад +4

    As someone with major depressive disorder, after I give any exercise regimen a chance, I really benefit from it and love doing it.
    But finding any motivation at my lowest, along with those unexplainable aches and creaks.... It makes it nigh impossible. This could be a short term or as needed boost that would be revolutionary.

  • @nikkiferretti
    @nikkiferretti Год назад +27

    For people with diseases like MS and ALS this type of medicine could change lives- especially when it comes to athletes that suddenly can't do what they love anymore. It's not just about losing weight; it's the benefits of exercise that people with illnesses can't necessarily get due to severe lack of mobility.

    • @Rumplegirlskin
      @Rumplegirlskin Год назад +1

      Exactly! I received my MS diagnosis at 21. Then a few years later I started noticing I could do my normal workout routines. Then when I was remitting I would do the normal routine and it would take it’s toll later. Now I’m being told no more working out for long stints or the regular number of days a week.
      Edit: As soon as I wrote this I heard about the side effects. Nope, no way 😂. The benefits do not out-weigh the risks in this case.

    • @vanitas.
      @vanitas. Год назад +1

      Unfortunately, this drug won’t help either patient with MS or ALS since the first one is an autoimmune condition and the second one is a neurological disease

    • @nikkiferretti
      @nikkiferretti Год назад

      @@vanitas. that's too bad. Those are the people that need something like this most. Thanks for the info!

    • @nikkiferretti
      @nikkiferretti Год назад

      @@Rumplegirlskin That sounds so frustrating- I hope medical research is able to progress enough in the next few years so you can be active to the extent you want again! You and others with conditions like yours are some of the strongest people I know. Keep fighting!

    • @vanitas.
      @vanitas. Год назад

      @@nikkiferretti I second your opinion

  • @Cylindropuntia
    @Cylindropuntia Год назад

    Great video guys!

  • @gamesturbator
    @gamesturbator Год назад +2

    You explain real science so efficiently and with such a great delivery, you absolutely amaze me. Do something with Scishow if you haven't already!

  • @Michael-yo3vu
    @Michael-yo3vu Год назад +5

    Working out is not just about the gains. Doing exercises is kind of like.. dancing! It makes you happy when you move your body.

  • @Noahsampeer
    @Noahsampeer Год назад +10

    I would love something like that. I used to be in ok shape but due to a medical issue in my neck, doctors have advised me not to do any exercise that puts impact on my spine. They even told me walking was bad. I ballooned up in weight due to the sudden lack of exercise and have only just started to get control of it some 3 years later.

    • @Noahsampeer
      @Noahsampeer Год назад +2

      @@gmail5367 I can swim and I have a pool available but only during the summer time and only when the owners are available. Unfortunately since I was retired (due to the medical issue I couldn't continue to work) am on a fixed income and can't afford a membership anywhere.

  • @KC9QII
    @KC9QII Год назад +1

    One thing to keep in mind is that dosing equivalents in mice and humans are very different due to their metabolism. They require much more of a drug to receive a similar effect. So the study that showed cardarine to have rapidly caused massive multi-organ cancerous tumors should be more than slightly concerning despite the high doses.

  • @Slug42069
    @Slug42069 Год назад +2

    as someone who is 50% disabled and has a hard time working out because of chronic pain this would be very helpful!!

  • @TigerAceSullivan
    @TigerAceSullivan Год назад +18

    i can see this being really useful for people who really cant lose weight without drastic measures because their body just Clings to it; people whove had any sort of eating disability in the past, or a lack of access to good food if any food at all, or recent ancestors in the same boat, all tend to have gene expressions that make it much harder to lose weight. and also for people with disabilities who cant move around much, or even if someone just broke a leg, regaining thay muscle after it heals would be much easier.
    im excited to see what the future holds!

    • @Sunscreen723
      @Sunscreen723 Год назад +2

      From personal experience ,not being able to lose weight is just a mental weakness ,nothing more ,everything else are just excuses .

    • @samdp42
      @samdp42 Год назад

      I wish you long lasting success of weight loss. I hope your internal dialogue doesn’t hold you back from keeping the weight off. ❤

    • @Mel-qr5ob
      @Mel-qr5ob Год назад

      @@Sunscreen723 Wow omg you need to go tell scientists "your personal experience", hundreds of studies of thousands of people have the OPPOSITE results of what your personal bias has figured out, sharing your opinion is gonna change the world!!!
      Like damn, who could have guessed that you, one person with only your own DNA to experience, would have the omniscience to know exactly how the other 8 billion people's DNA combos would affect their weight with more detail and precision than a scientist can.
      Gee I wish I could see someone's DNA just by looking at them with my eyes like you can.
      Nick you should change your username to "God" bruh

  • @egonzalez4294
    @egonzalez4294 Год назад +13

    I get the feeling a true exercise pill would also cause the same distress exercise causes, there are a lot of neurological adaptations to exercise, exercise triggers stress signals and you get adapted to stress mentally, that's how it kills anxiety and depression; exercise throws lots of hormones afterwards; a true exercise pill would cause distress upon consumption, maybe your muscle fibers tear up too. I think an exercise pill would only be able to partially tap into the advantages of exercise.

    • @seymur7422
      @seymur7422 Год назад +3

      well that depends of what's in the pill, there's some pills that reduce muscle fatigue.

  • @stephank9285
    @stephank9285 Год назад

    I realy thought this would just be an click bait video but, It is, as always form Asap SCIENCE, a awesome video! Thank you for putting great content on RUclips!

  • @guitaro5000
    @guitaro5000 Год назад +2

    Damn! It's fall fun and games until the commercial is about to end and you hear the side effects !!! My goodness.

  • @toomanyopinions8353
    @toomanyopinions8353 Год назад +3

    As someone who's chronic pain makes exercise very difficult, this would be life changing.

    • @danielprince6944
      @danielprince6944 Год назад

      The pills cause cancer unfortunately I'm sorry you had hope for it. It showed that animals get cancer even with smaller doses

  • @jer103
    @jer103 Год назад +25

    Drugs = side effects
    I would want to know what else GW501516 does to your body.
    Also, in a longitudinal study, it would be key to know 5 to 10 years what happens after taking this drug.

    • @JeremyFacer
      @JeremyFacer Год назад +9

      In the lifetime rat study if gave all of them a shit load of tumors… so yeah

    • @Lightyagami-tx2xb
      @Lightyagami-tx2xb Год назад

      It will be the wonder pill which will make you fit as well as make you week also because at the end you easily catch cancer and other disease easily so lol what the use of it.

    • @andyhaochizhang
      @andyhaochizhang Год назад +1

      We don't even know if it even works on humans. And IF it works on humans does it work only on sufficiently inactive people or on everyone.

    • @my_beard_vs_your_beard6001
      @my_beard_vs_your_beard6001 Год назад +2

      It causes cancer. Those rats all died of cancer.

    • @cooluser23
      @cooluser23 Год назад

      It causes cancer, which is why the research on it was abandoned in 2007. None of this is new.

  • @Idontwantyourcookie
    @Idontwantyourcookie Год назад +1

    One of the things in the slides show was the implication that exercise prevents depression, but was that controlled for the fact that a depressed person just might be less likely to exercise?

  • @octaneblue6
    @octaneblue6 Год назад

    "GW501516 (also known as GW-501,516, GW1516, GSK-516, Cardarine, and on the black market as Endurobol[1]) is a PPARδ receptor agonist that was invented in a collaboration between Ligand Pharmaceuticals and GlaxoSmithKline in the 1990s. It entered into clinical development as a drug candidate for metabolic and cardiovascular diseases, but was abandoned in 2007 because animal testing showed that the drug caused cancer to develop rapidly in several organs."

  • @eatmorechicken1064
    @eatmorechicken1064 Год назад +46

    This sarm has been out for years, it's called Cardarine. It's fairly popular in the fitness industry. I tried it for a couple weeks and seemed to feel better in general

    • @Samkynhneigo
      @Samkynhneigo Год назад

      Did you try sr90... ?

    • @Lightyagami-tx2xb
      @Lightyagami-tx2xb Год назад +16

      Sarms are steroid bro

    • @trokut724
      @trokut724 Год назад +2

      @@Lightyagami-tx2xb so?

    • @WobblieSkellie
      @WobblieSkellie Год назад +4

      @@Lightyagami-tx2xb No, they're not.

    • @jigors3
      @jigors3 Год назад +14

      @@Lightyagami-tx2xb wrong. They are both PEDs but both are not steroids. Cardarine also isn’t a sarm it’a a ppar. It’s also a banned substance since athletes started popping for it in 2008.

  • @182punkbunny
    @182punkbunny Год назад +30

    The one thing I keep thinking through the video is “wonder how many anti vaccines people that are always ‘I don’t know what’s in it’ argument.. will take this pill without thinking about it twice”

    • @Drag0zard
      @Drag0zard Год назад +2

      So what you're saying is you don't care what you put into your body.

    • @wparkerunc
      @wparkerunc Год назад

      @@Drag0zard what hes saying is that since there are anti vaxxers that say that they wont take the vaccine without knowing whats in it, he is wondering how many of those anti vaxxers will take this pill without thinking about whats in it.

    • @Lyth
      @Lyth Год назад +6

      @@Drag0zard No, he's saying that there is likely plenty of people who "care" when it comes to a vaccine for public health, but wouldn't for a random pill. You completely missed his point lol

    • @Samuel.Sharman
      @Samuel.Sharman Год назад +6

      @@Drag0zard you should get a litter picker if you want to keep reaching like that my guy

    • @InvisibleHole
      @InvisibleHole Год назад

      @@Lyth uh a pill that magically solves everything is basically as it seems. A vaccine regulated and tested by multiple companies and the government you can't compare. Also supplements like this would be regulated after market LMAO no fuckin way. Yet there are defo anti vaxxers who would be uneducated enough to fall for this pill

  • @calinmarie5974
    @calinmarie5974 Год назад

    neeeeed this. wonder when/if it'll ever come out

  • @BMohantyone
    @BMohantyone Год назад

    Put a smile on my face. ASAP ❤️ always

  • @nolmao366
    @nolmao366 Год назад +15

    Waffles with nutella

  • @enos128
    @enos128 Год назад +20

    I would definitely take it! I have problems with my joints and it’s becoming more difficult to exercise much besides just walking.

    • @giovannamoro8564
      @giovannamoro8564 Год назад +1

      Walking or swimming is all you need . The rest is just a trend .

  • @scoobydoo3888
    @scoobydoo3888 Год назад

    Yo i haven’t seen you since big brother Canada loved you on it!.

  • @fdm2155
    @fdm2155 Год назад

    I could see something like this helping folks who exercise too. I know I don't get the same results from exercise that I saw 20 years ago. That can be very disheartening. I'd love to have something that boosted the effects of my exercise routines.

  • @hennnerz
    @hennnerz Год назад +3

    Love the science behind your channel!Please can you do a video on epilepsy and seizures?

  • @BobSmith-tm2kj
    @BobSmith-tm2kj Год назад +4

    something like this would be wonderful for physically disabled people who actually CAN'T do most exercises.

  • @sadssddsd2926
    @sadssddsd2926 Год назад +1

    juuuust the minor inconvenience of CANCER!!!! love how u mention that after SEVEN MINUTES , thumbs up reallly , great science work

  • @davidcooney196
    @davidcooney196 Год назад

    Love the format. More like the format from a few years ago.

  • @jasonhowland2903
    @jasonhowland2903 Год назад +27

    If you think there’s not going to be commercials about this in 10 or 15 years your not paying attention

    • @karlph1sher344
      @karlph1sher344 Год назад +2

      There are fitness influencers promoting this and other sarms already.

    • @fastshuther
      @fastshuther Год назад +2

      You’re*

    • @InvisibleHole
      @InvisibleHole Год назад

      You are the reason americans are stereotyped as, 'completely idiotic' (the drug came out in the 90s btw)

  • @MugiHatesYou
    @MugiHatesYou Год назад +3

    This should straight up be reported for misinformation. Greatly exaggerated.

  • @TrollCarl
    @TrollCarl Год назад +1

    This is amazing! I exercise alot but this pill would help so many people!

  • @caitlinsumm140
    @caitlinsumm140 Год назад +1

    This is super interesting! I have a condition called Postural Orthostatic Tachycardia Syndrome (POTS) and one of the best studied treatments for it is exercise. The problem, is that POTS also causes exercise intolerance, and I can only do extremely basic forms of exercise (think walking two blocks max, with a walker), before having a syncopal episode. A drug like this would be insanely beneficial in breaking the self perpetuating cycle my condition has me stuck in.

  • @Garden-of-Scarlett-Eden
    @Garden-of-Scarlett-Eden Год назад +4

    As someone with ME/CFS that is struggling to restore my capacity for exercise since a bone break - something like this might honestly be a life saver

    • @Garden-of-Scarlett-Eden
      @Garden-of-Scarlett-Eden Год назад +1

      @@r.i.petika829 Instead of ignorantly inferring that a debilitating chronic illness that clasifies as a significant disability is "poor discipline and self control," maybe go educate yourself

  • @bleuo.d.1652
    @bleuo.d.1652 Год назад +6

    love this video and always loved u guys but don’t start click baity thumbnails ☹️

  • @mangoblaze
    @mangoblaze Год назад

    As someone with a chronic disability that limits the amount of exercise I can regularly do safely this kind of research is incredible and sorely needed

  • @GrahamLikeTheCrackers
    @GrahamLikeTheCrackers Год назад

    I found a hack to do more exercise: my car died and I got an e-bike instead to save money. Now I have to bike everywhere. The motor helps me go farther and not be a sweaty mess, but I'm still spinning the pedals way more than I ever would have before.

  • @DeclanMBrennan
    @DeclanMBrennan Год назад +5

    That was fascinating and very well explained. However the list of side effects is a Halloween horror story.

  • @sophiewalsh5492
    @sophiewalsh5492 Год назад +9

    Y’all, please keep in mind that weight loss is not the benefit of exercise. Like, yea, exercising can be a contributing factor to weight loss, but the reason that exercise is good for you is not because it reduces weight. Reducing weight just happens to be a side effect sometimes. But exercise is soooo good for you for other reasons, and it doesn’t stop being good for you if you aren’t losing weight if you’re gaining weight even. Exercise is for everybody regardless of weight!! It’s probably the best thing you can do for your overall health other than maybe quitting smoking if you smoke. Please do not be motivated mainly by weight loss if you’re trying to get into a new exercise routine. Weight loss is very difficult and if you’re trying to measure your success with a new exercise routine by how much weight you lose, you’ll probably struggle more than you need to and you might burn yourself out just because you aren’t seeing the results you want, meanwhile you’re missing all the other benefits going on. You can improve your health with exercise and still stay the same weight or even gain weight at the same time, and exercise is STILL good for you. Weight loss is not the definition of improving health

  • @jenpenn22
    @jenpenn22 Год назад

    I was an athlete before being disabled. Meds and slowing down made me gain weight, making exercise even more painful. This video made me cry

  • @JohnJames_Wpg
    @JohnJames_Wpg Год назад +1

    I was hoping Mitch would be shirtless for this, like in the thumbnail.

  • @saya8349
    @saya8349 Год назад +9

    This pill will be great for clinical depressed people. Since exercising is so hard for us, but not exercising makes our condition worse and exercising helps.
    Using it to give someone the strength to actually exercise would be really helpful!! Like same with antidepressants, medical prescription is the best way to not use it too much but get the benefits that could help people to have it easier exercising!

  • @WhyHelloShelby
    @WhyHelloShelby Год назад +7

    I wonder if this could be used short-term to help people (like me) who really hate exercising partially because their endurance is so low. So maybe something like this could help get into a rhythm and then you can be taken off the drug

    • @OMGanger
      @OMGanger Год назад +1

      Just do one more push-up every day

  • @jayrey5390
    @jayrey5390 3 месяца назад

    As someone who is disabled from the knee down and exercise causes more pain than my meds can manage - this could be a game changer

  • @highestqualitypigiron
    @highestqualitypigiron Год назад +2

    I've actually use this drug myself, 10mg daily. I used it primarily to improve my lipid profile as my HDL was borderline out of the reference range (due to my high testosterone)
    I have to say this drug honestly feels like magic. My cardio is phenomenal and I can eat literally anything I want and my blood work stays good and even when bulking I cannot get above 15% bf (approximately) no matter what and how much I eat.

  • @bigpapadrew
    @bigpapadrew Год назад +3

    I think I would take a pill that complements my exercise. I don't think any pill could every replace what you gain through effort and sweating. So I'd be ok with a supplement to my exercise, but I would never abandon exercise (gym, inc. cardio and weights) completely

  • @Fenksta
    @Fenksta Год назад +4

    As someone who struggles to START an exercise regimen, this is great news :D

    • @Fenksta
      @Fenksta Год назад +1

      @Contingency IBCT not every comment on the internet is to be taken with full seriousness :)

    • @dvra9337
      @dvra9337 Год назад

      stop fapping everyday and you will find yourself in the gym more

    • @Fenksta
      @Fenksta Год назад

      @@dvra9337 what a mature response

  • @Lady8D
    @Lady8D 8 месяцев назад +1

    I'm disabled and almost entirely bedbound, unable to exercise - I would love a pill like this

  • @JungledGeorge
    @JungledGeorge Год назад +1

    I was so ready to scream "take my money" then Mitch had to tell us about the downside 🐭🐭

  • @ChocolatesAfterDark
    @ChocolatesAfterDark Год назад +3

    Wouldn't even think about it, helps if you're sedentary but I imagine it might help even if yo do exercise, as it pushes a little extra or you're just at a different baseline because of it so you could do more, maybe all you can do is walk at 3mph but then because of this pull affecting your baseline you manage to go 4 or 5 or 6mph which would in turn have greater benefits (obv up to a point). I assume diminishing returns on the truly very active but yeah, for the cat majority of the people who sit at work at day (drivers, bankers, factory workers, corporate people) this would be I think a great development

    • @esmee6308
      @esmee6308 Год назад

      Basically this, I already have a structured exercise regime and active lifestyle however no side-effects and the effects adding up alone is a good reason to consider it. Or post surgery (got some health issues) to make the recovery easier and a less jarring prospect. However, it's very important what the risks and side-effects are, there's hardly ever a magic pill, just a lesser evil.

  •  Год назад +7

    The point of exercise is not only for physical health but mental health. The feeling reward after finishing a marathon or tough workout. A pill doesn't replicate that feeling. A pill could be a supplement but certainly not a replacement for going for a brisk walk or physical activity.

    • @InvisibleHole
      @InvisibleHole Год назад

      Wrong drugs can have all kinds of effects ever get high? A pill can definitely give you the high of finishing a marathon thats for sure.

  • @nycto5335
    @nycto5335 Год назад +1

    This sounds nice. It could be used to make up for lack of time. For example, if I had the option to use such a pill (ignoring the side effects) I'd probably still work out but I'd lower the amount of time spent working out with the pill. For people that barely have time for anything much less working out this would help them keep their health in check too. Overlal it sounds interesting and the possibilities seem pretty nice.
    Hopefully testing, modifications and all that shows it doesn't have super averse effects. It's nice to imagine a future where I can take a pill or pills to makes up for lack of time to exercise but them again an argument can be made that we should set up the world so everyone has enough time to do stuff like that.
    This would definitely be most beneficial for people that physically can't exercise. Im sure there are plenty of people mentioning their own stories down in the comments.

  • @holiver1981
    @holiver1981 Год назад

    This is going to be essential for space exploration

  • @arnav5680
    @arnav5680 Год назад +5

    Nikocado avacado will mukbang these pills

    • @jonawa1573
      @jonawa1573 Год назад +1

      If These Drugs save His Life then this is the best time Line ever

    • @arnav5680
      @arnav5680 Год назад

      @@jonawa1573 what will be the consequences?

    • @jonawa1573
      @jonawa1573 Год назад

      @@arnav5680 short answere, we dont know yet
      consequences are with every drugs but Sometimes they can do more good than Bad, thats the Important Point

  • @kellytibbs3815
    @kellytibbs3815 Год назад +3

    Shirtless clickbait thumbnail is clickbait 👹🤣

  • @rebekkahschultz9615
    @rebekkahschultz9615 Год назад +1

    Yeah, given your points in the video, I think it's a reasonable idea in theory, so long as we workshop it thoroughly, and distribute it ethically and equitably. Prescribing it for someone post-surgery for example, I think is a great use for it. And it seems like it would be very helpful for some disabled folx in the comments open to it.
    Just I think we also do need to pair this with creating infrastructure that lends itself better to movement. Paths that center cyclists and pedestrians, for example. Prioritizing workplace accommodations. Honoring treaties with indigenous nations so they can freely exercise their right to roam. Having healthcare systems that give people access to the mobility devices they need and want.

  • @BeatleBabe
    @BeatleBabe Год назад +1

    If it could ever be made without the scary side effects, hell yeah I'd take that in a second! I had VERY early onset congestive heart failure (we're talking diagnosis at 14) that makes tolerating exercise very hard, but something like this could be literally life changing.

  • @winterx2348
    @winterx2348 Год назад +3

    I have chronic fatigue syndrome. I can barely move at all, haven't left my home in months, and my muscles are atrophying. A miracle pill like this would be a game changer for people like me. Nobody cares about that, though, they just want to be skinny, and there's more money in appealing to those people.

    • @Josep_Hernandez_Lujan
      @Josep_Hernandez_Lujan Год назад

      Many people who have CVS are helped by ADHD meds like Adderall, Vyvanse, and Ritalin. Find a doctor open to that kind of treatment

    • @winterx2348
      @winterx2348 Год назад

      @@Josep_Hernandez_Lujan Thank you for the unsolicited medical advice. We tried stimulants already and they put me in the hospital.

  • @Argosh
    @Argosh Год назад +24

    Did you miss the part where long term use can cause cancer? That's kind of an important side effect to not mention up front...

    • @brentsblackparade
      @brentsblackparade Год назад +9

      did you not finish the video

    • @pairoz7054
      @pairoz7054 Год назад +7

      he literally said that lol have you watched the video or something

    • @Argosh
      @Argosh Год назад

      @@pairoz7054 "up front"...

    • @thatwasmethere3526
      @thatwasmethere3526 Год назад +1

      This guy trying to ruin people without a care 🙂

    • @teehee4096
      @teehee4096 Год назад +1

      Living can cause cancer too

  • @justinfowler2857
    @justinfowler2857 Год назад

    I love naming a doped up mouse after doped up Lance armstrong.

  • @Nytoav
    @Nytoav Год назад +1

    As someone with chronic illnesses that make it very difficult to exercise or manage my weight properly, something like this could literally save my life. I'm very interested to see how these studies progress.

  • @w1ll14m5
    @w1ll14m5 Год назад +11

    This is huge. Many people are stuck in their diets or lifestyles, and this pill could be the key to helping those people transition to happier, healthier outcomes.

  • @ChoiMinyuk
    @ChoiMinyuk Год назад +3

    It is this even real?

  • @UlmaAum
    @UlmaAum Год назад

    I love you asapers 💜💜

  • @aizat27
    @aizat27 Год назад

    This pill would make a good premise for a sci-fi movie.

  • @PygmaApril
    @PygmaApril Год назад +5

    Sugar coating steroids huh?

    • @verymotivated7193
      @verymotivated7193 Год назад +2

      We’ll all turn out like that buff Jerry the mouse meme

    • @InvisibleHole
      @InvisibleHole Год назад

      not a steroid. I doubt you can identify what actually makes a steroid a steroid

  • @oonabot
    @oonabot Год назад

    omg as a disabled person with mobility issues this would be AMAZING for me!

  • @GajanaNigade
    @GajanaNigade Год назад

    *Sees the video in feed*
    *Clicks to confirm suspicions that it would somehow cause cancer*
    *Leaves in peace*

  • @stxejn
    @stxejn Год назад +1

    As someone who suffers from hypothyroidism, this would be a game changer.

  • @TheGoodContent37
    @TheGoodContent37 Год назад

    As someone with chronic depression something like this would be awesome.

  • @acmulhern
    @acmulhern Год назад +1

    I think that double decker bus illustrates the issue perfectly. The problem really is work. We have invented a world where everyone spends most of the day working, and most of this work in the west is sedentary. It's much easier to get your daily exercise of it involves movement than trying to get your exercise in after a long day's work.
    And thus issue is increased by the commute. If you have the opportunity to walk, bike or bus yourself to work you're going to move more than if you're forced to drive your car.

  • @DawnKraken
    @DawnKraken Год назад

    One thing that needs to be understood is that the main reason for most people in the US and Canada not being fit is due to a city design that exclusively promotes cars, often at the cost of lives.

  • @StayCoolKeto
    @StayCoolKeto Год назад +1

    *Cardarine has been out for agessssssssssss, bit slow on the video upload here lol. Really helped with my breathing when my asthma was bad* 💪👍