"Interrupted" reprogramming with Yamanaka factors reverse epigenetic age | Steve Horvath

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  • Опубликовано: 15 янв 2025

Комментарии • 21

  • @FoundMyFitnessClips
    @FoundMyFitnessClips  4 года назад

    *Watch the full episode:*
    ruclips.net/video/A_aaBKubJnA/видео.html
    *FoundMyFitness episode page:*
    www.foundmyfitness.com/episodes/steve-horvath
    *More clips from this guest:*
    ruclips.net/p/PLrGxo-5Uw8gLoQZzyp3xQgfkGEhc-nR-t

  • @davidivers9295
    @davidivers9295 4 года назад +8

    Please pass the Yamanaka Factors!

  • @sdicooking6944
    @sdicooking6944 Год назад +2

    Can you activate yamanaka factors on brain cells without losing memory?

    • @exmodule6323
      @exmodule6323 11 месяцев назад

      Of course - memory is not stored in cells; rather they are a feature of your connectome or the structure of connecting matter between cells

    • @sdicooking6944
      @sdicooking6944 11 месяцев назад

      @@exmodule6323 Has this been done in animal trials? any links to research?

  • @UHFStation1
    @UHFStation1 3 года назад +2

    What if we use Yamanaka factors to heal, but use other drugs to wipe epigenetic noise to reclarify the cell's identify?

    • @Melanie____
      @Melanie____ Год назад

      Im not sure this is understanding the factors. The yamanaka factors can change a cell into a stem cell like state similar to embryonic cells. They recently discovered that three can bring cell back to (that cell type) age zero. The epigenitics is encompassed in this.
      Also the SIRT1s involved in regulating epigenitics order are deprioritised from that function in order to fix dna damage for a time.
      So if the cell is healed the epigenetic order will inturn return.

  • @jessehorstman
    @jessehorstman Год назад

    Can this be done with policosanol?

  • @dimaknopf
    @dimaknopf Год назад

    I'm gonna be on the lookout for a scientist that looks unusually young in old age.

    • @exmodule6323
      @exmodule6323 11 месяцев назад +1

      Dr David Sinclair looks late 30s - he’s nearing 60

  • @richardnunziata3221
    @richardnunziata3221 2 года назад +1

    How about we just let people take responsibility for their own lives and let them try it in a clinical setting.

    • @exmodule6323
      @exmodule6323 11 месяцев назад

      Currently, I would bet there’s a 99.9% they would experience organ failure and die. This discovery is on par with having discovered a nuclear explosion, but lacks the control mechanism to carefully administer in vivo in a human

  • @debasishborthakur2141
    @debasishborthakur2141 2 года назад +1

    Hie.. I'm from India.. I really like this guy..👍 He is just great..

  • @ScienceofCardio44
    @ScienceofCardio44 4 года назад +2

    Facsinating.

  • @ShowMeWhatINeedToKnow
    @ShowMeWhatINeedToKnow 4 года назад +5

    I'm not sure if I want to extend my life -- the way the country is going.

  • @nandoluislopes
    @nandoluislopes 3 года назад +1

    It looks like allowing the Yamanaka's factors to work freely is dangerous because cells would lose their identity. But this kind of assumes that the goal is anti-aging. Would it be possible to attack viruses with Yamanaka´s factors? for example...

    • @Captain_Mulligan
      @Captain_Mulligan 2 года назад

      Gene editing cures your herpes, not yamanaka

    • @nandoluislopes
      @nandoluislopes 2 года назад

      @@Captain_Mulligan The point is turning virus back into stem cells..

    • @Melanie____
      @Melanie____ Год назад

      Using three of the yamanaka factors brings cells to age zero without it going into embryonic state.

  • @universe25.x
    @universe25.x 4 года назад +2

    Just tell us what’s the cure of aging!! Is there any.?? I don’t want any wrinkles on my face and body😢😢

  • @alicecarrick4342
    @alicecarrick4342 Год назад

    dont tell me then