Why Cirrhosis causes Gynecomastia, Spider angiomata, Palmar erythema - Ever Wonder Why?

Why Cirrhosis causes Gynecomastia, Spider angiomata, Palmar erythema - Ever Wonder Why?
Cirrhosis of the liver can cause enlarged breasts in males (gynecomastia), spider angiomas, and palmar erythema (red discoloration of the skin of the palm of the hand). Normally, liver metabolizes (degrades) estrogen. However, in cases of liver cirrhosis, the liver is unable to metabolize estrogen leading to increased serum estrogen level which has an effect on breast size (gynecomastia). Normally, liver makes plasma proteins (e.g. albumin, globulin). Lectures for doctors, nurses, pharmacists, physician assistants, MBBS, USMLE, NCLEX, NPLEX, COMLEX.
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