Antiulcer Activity By Pylorus Ligation Method in Rat | Ex-Pharm Software | हिंदी में समझिये

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Antiulcer Activity By Pylorus Ligation Method in Rat | Ex-Pharm Software | Antiulcer | ENGLISH - • Antiulcer Activity By ...
Ulcers. A peptic ulcer is a sore on the lining of your stomach, small intestine or oesophagus. A peptic ulcer in the stomach is called a gastric ulcer. A duodenal ulcer is a peptic ulcer that develops in the first part of the small intestine (duodenum). An oesophagal ulcer occurs in the lower part of your oesophagus. Proton-pump inhibitors are a class of medications that cause a profound and prolonged reduction of stomach acid production. They do so by irreversibly inhibiting the stomach's H⁺/K⁺ ATPase proton pump. They are the most potent inhibitors of acid secretion available.
Pylorus ligation stimulates the gastric acid output by a long vago-vagal reflex in innervated animals and by an intramural reflex in chronically vagotomized animals. Nephrectomy reduced the acid response to pylorus ligation in vagally intact rats but enhanced it in vagotomized rats.
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