Managing Side Effects of Thiamine Supplementation: The Paradoxical Reaction
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- Опубликовано: 4 сен 2024
- Some individuals experience negative reactions and the worsening of symptoms when they begin thiamine repletion therapies using the more biologically available formulations like thiamine tetrahydrofurfuryl disulfide (TTFD). Dr. Derrick Lonsdale calls these "paradoxical reactions".
In this video, I examine the biochemistry beyond these reactions and provide some hypotheses regarding why they happen and how to mitigate them.
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![⚠️Vitamin B1 Thiamine vs. Benfotiamine [STOP Chronic Pain]](http://i.ytimg.com/vi/BFjwxefiBUY/mqdefault.jpg)
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I just want to go back to 1962 where everything was simple you didn't have to be a scientist to wake up and feel good everyday
You said it!!!
The secret of people back then was cocaine
The year of my birth! (9/11/62) I also miss those simpler times...
I wanna go back to the 90s
Ha............. well put and so damn true.
Thiamine megadosing cured my covid long haul syndrome in five days. I literally went from being bedridden to my normal self in under a week. It truly was a miracle!
What form did you take, and how much? I and two of my teens are long haulers. Our main issue is histamine intolerance.
@@reddawn8230 Hi Angela! Three to four months into my suffering, my wife came across a Facebook long-haul forum where person after person was claiming that b1 was turning their situation around. She initially handed me 6 100mg powder capsules (600mg). She returned 45 minutes later to ask how I felt I sat up in bed and noticed that my symptoms were 50% better! I then proceeded for a week or so taking 500 mg with each meal of the day. By the end of that, I was 100% cured, now I just take a single capsule of B1 with breakfast. I thought my life was over, that it was going to be permanent. I truly hope and pray this provides relief for you. Please research it thoroughly, while I had zero adverse reactions to these megadoses everybody is different. I have read that fighting covid can seriously deplete your thiamine levels, and it's the mega dose that brings everything back into order, not just the one mg daily recommended amount. B1 is a water-soluble vitamin, so to my knowledge taking a lot of it can't hurt you as you just excrete the excess in your urine.
@@miketexas4549 that’s awesome! I have the benfotiamine form and another b-1 that I forget the name of... does it matter what kind I take?
@@reddawn8230 Definitely DO NOT megadose the benfotiamine, it is fat soluable and will likely make you sick. Stick to the Thiamine b1 and you should be fine. Also, I hear tablets are less effective as they are not as readily absorbed, and magnesium is also required for proper B1 metabolism. Be careful with magnesium, too much and it can upset your stomach. best wishes and best of luck!
@@miketexas4549 benfothiamine made my feet 🔥
It's been 3 weeks since I started a Thiamine Mega dose and WOW! It made a huge difference. It's like my gut all of a sudden decided to start working again! I worked up to 1200mg Benfotiamine, Creatine as a methyl loaner, potassium iodine & selenium, molybdenum and Glutathione for support.
How was your first week?
Christ that's a lot of supplements, if only I had enough money for all of that. :(
@@SeminarChauffeur What brand are you buying that is so expensive? I’ve seen deals on the things mentioned in that post.
@@Lilly2Gbtg ….you don’t know their financial situation.
@@SeminarChauffeur Start where you can. Start with benfotiamin and dont go that high. 300mg per day maybe + magnesium and then eat rich foods in potassium and B vitamins. Goodluck
0:00 - Introduction
2:05 - Key Points
3:33 - Other B vitamins
4:58 - Electrolytes
10:28 - Glutathione
15:41 - Methylation
20:42 - Sulfoxidation
23:09 - Conclusion
I love ❤ you. Thank u MVP!
Thank you ❤️
Thanks 🙏🏻
What about using sub lingual thiamine?
I got very dizzy and tired the next morning after taking 450 mg of Benfotiamine w Thiamin the day before (didn't take at night). Could that happen??
And how about just slowly increasing the B1?
I suffer from a tbi that happened approximately 33 years ago. Part of my brain is actually dark matter. How I can function normally is beyond me. However, I have been diagnosed with severe depression, anxiety, and panic attacks….As well as being exhausted all the time. I came across your videos today and I am beyond ecstatic this might help with some of my health issues. Time for a little experimenting!! Can’t thank you enough for your videos!!
How have these supplement protocols helped you so far?
@@BrendenNichols I am off of my antidepressant. Upped my vitamin B intake, magnesium, and other vitamins. Gradually increasing them so I don’t shock my system too much. Haven’t had any panic attacks but my anxiety has a ways to go. I overthink every thing, finding ways to manage it. Still exhausted but it has only been a few weeks. I can’t comment on my memory but will see what the future brings. I remain optimistic 🤗.
@@user-bm2dt2si4n Thank you for the response! I’m always curious to see how different everyone’s experience is with using supplements. I’ve never taken antidepressants or antianxiety medication (though I have severe anxiety some days), but I have supplemented with various B-vitamins over the last four years. I particularly supplement with vitamin B12 and less frequently with niacin, which has been beneficial to my anxiety on certain days. I tend to only use the niacin in extreme cases, otherwise I supplement with vitamin B12 and vitamin D primarily. I hope your supplement journey goes well! You’re just three weeks in and I’m sure your body is continuing to adjust to this inundation of nutrients, so you could start to feel markedly better in a week or two. Clearer mind, lessened anxiety, and higher quality sleep at night. I notice that if I go without taking B12 for longer than a week, my sleeping pattern is thrown off horribly, causing me to stay awake a lot longer than I normally would. I use vitamin D to improve my skin health, but using too much at once worsens my anxiety. This is particularly a problem with the liquid form because of how concentrated it is.
Continue on your path to optimal health and a sound and sharp mind. It may take a while, but the benefits are certainly worth it. I hope you’ll never have to rely on pharmaceutical medication again.
Yo have you tried keto I've heard people healing tbi's with keto
@@phines93 no I haven’t. I work with someone who is on that diet and what I’ve seen…..not interested in it. I appreciate the info though ☺️
This is great information but also extremely overwhelming for the laymen who wants to start a protocol to heal. I have gut issues, possibly SIBO, and tend to be super sensitive to taking anything new and there are so many options for supplements that might be beneficial with TTFD that I don't even know where to start!
Start with amount b1 you can tolerate.
Thank you for this topic. I'm starting with 100mg of thiamine. I have benfotiamine 300mg too. I'll start it next week. Best to take it with food? Exciting and a little scary. 😊
@@lenas5613lol you saw a chick and started to ask her. Lmao 😂
Benfotiamine made my GERD worse💔
@@ahlaali7934 what’s gerd?
Holy crap, I'm SO CONFUSED!! Here I thought there was hope for me, and that B1 might be the answer, but this video is so over my head and now I'm more confused than ever. I guess i won't be trying this anytime soon 😭
The info in this video is for outliers who respond negatively. I have a video called "How to start mega dose thiamine" and it is quite simple
@@EONutrition
I will watch that one, thank you. I was watching this video so that if I decide to try the B1, I would know what to expect if I responded negatively, but it's just too confusing.
Same here..confused and now frustrated too.
@@boe1956yep, just when you think you understand all the risks involved, you watch another video & realize you didn't actually know much. And you also realize that if you do start taking Thiamine and you experience complications, you won't be able to get help from Doctors because they are clueless so you'll be left to try & figure things out on your own! And I know that not everyone will experience complications but there's no way to know if you're part of the small percentage of people who will actually experience complications!
Feel the same. I have watched many videos about how good thiamine is. Then I saw a comment from a woman who got a lot of hair loss and started to search for side effects and now I instead feel afraid to try 😅
So interesting. Thank you. I'm chronically ill and at my worst I was bedridden for 8 years. I was trying for years (3) to take folate. I couldn't get above a crumb without debilitating side effects, and yet, I'd developed folate related anemia (megaloblastic). Last year the doctor didn't listen to me at that appointment and wrote a script for a high dose of Folic Acid. I threw that out because I have a homozygous MTHFR mutation. Within a week or so it dawned on me (by stumbling onto some information) that, despite having normal blood serum levels of magnesium, I was deficient. I started supplementing (had avoided magnesium supplementation because I have CKD - idiopathic... likely from chronic folate deficiency) and immediately could take whatever amount of Folate I wanted. My health improved a tiny bit. (I've tried benfotiamine and haven't found it helpful, though I'm still taking 100mg a day.)
Have just stumbled onto to the thiamine connection and given my past history, including things that helped me get better but were compounded by too many variables at the time for me to sort out what had and hadn't helped, and defects in TPP (loads of homozygous TPK-1 mutations), transketolase mutations, and a couple of mutations associated with Thiamine-Responsive Megaloblastic Anemia Syndrome and Thiamine Metabolism Dysfunction Syndrome 5, this makes perfect sense. I also have mutated SLC19A3 genes - out of 17 SNPS two are homozygous mutations, four are heterozygous, and with three there's not enough information.
I've also had a very slow heart rate and low blood pressure all of my life and ridiculously slow rate in recent years (in the 30s and lower 40s). Diagnosed with multiple chemical sensitivities and ME/CFS... a lot of the symptoms of Beri Beri fit with that. I'd looked at wet Beri Beri before (given heart symptoms that show up as nothing) but thought, "Surely a doctor would have considered this." I could still have ME/CFS (I have 5 mutations of a gene that people who are severe with ME/CFS typically have 3 - yet, ME/CFS can happen to almost anyone as the mutations are common), but this looks promising and I have supplements on order. I also wonder if so many of us with ME/CFS who have had very slow onset aren't deficient in thiamin. I don't have potassium wasting because I take olmesartan which is potassium sparing and between that and an ACE mutation, I have to watch my potassium. So, I'm good there. I have to take sodium because of that and because I have unexplained salt wasting (a little known symptom of a thiamine deficiency can be salt wasting). I'm thinking of going off of olmesartan because it increases my fatigue.
I'm also diagnosed autistic and to be fair I have genes for the same. Some of the B1 genes that are mutated are also related to a biotin deficiency and based on my nails and how much biotin I take just to keep them from painfully tearing and splitting, my body's doing a poor job with that vitamin as well (they've gotten a bit better with my being able to consume folate). Hopefully, thiamin can help with that process.
I'm in my mid 60s and have been noticeably unwell and without stamina since I was 8 and was the working sick until I became seriously ill / disabled 19 years ago. When you've been this sick for so long, it feels dangerous to have hope, but I am hopeful.
I am so glad I stumbled onto information about this and your video.
When I take NAC, it turns the soles of my feet purple red and makes them very hot and incredibly itchy. I can nebulize reduced glutathione (one of the best ways to get it). I hadn't noticed any real benefit before, but perhaps with thiamine, I'll finally see some.
Good luck. Its horrible feeling this type of chronic illness. Its very socially isolating as well.
@@universaltruth2025 Thanks, and yes, it's terribly isolating. And many people experience friend and partner flight and even family flight. In a way, Covid isolation helped me come to grips with it and I'm more comfortable with the years of isolation that I've been enduring.
@@IExpectedBSJustNotThisMuchBS I’m doing nebulized glutathione too. I have severe pots and cfs bedridden 12 yrs.
I’m up to 225 mg hcl thiamine. I have tried several times to take it I try the other forms I couldn’t tolerate they made me so much more fatigued. But finally it seems like I’m tolerating I’m going slow. I use mag taurate and mag citrate. I try to get my potassium from food coconut water and a goat mineral whey powder. I take a multivitamin and a little bit of a B complex. I was using NAC for a couple months but I started having very gritty feeling eyes like something was in them all the time I discovered that NAC really dries you out that’s why they use it for lung infections and mucus. I stopped using it and it cleared right up. Dr Ben lynch says he if you need glutathione you should just take it and not NAC
Hi Madison, thanks for sharing your story and I'm sorry you e had to deal with this for so long.
I'm interested in what are the mutations for the thiamine anemia response? I've had the genetic testing, but don't recall anything about thiamine deficiency or anemia, though I've suffered from both. Also have been tired my entire life. I don't thin I process sulfur well, in fact have the SNP for that.
My nails have become terrible over the past 7 years. They were splitting terribly in 2014, until I started taking folate daily. But in the past 2-3 years they have started to flatten and I fear spooning. When I try to supplement with Seeking Health Folate, I become irritable.
I hope you'll see this and share how much folate you take and how long it took to help your nails. I'd really love to figure some of this stuff out before I croak, because the past five years have been especially crummy. TIA.
Man your work on thiamine has changed my life. Thank you man! Glad you're back.
haven't you stopped the carnivore diet?
@@ekkekristo I'm not Frank lol
@@frankiesfairyboytwinkclub Identity theft is not a joke, Jim! Millions suffer every day!
Thank you so much for this information Elliot. I started to increase thiamine a few days ago, and have started to experience those symptoms. Good to know what it is and why. Very grateful for your incredible knowledge.Thank you😀
For what reason did you take thiamine?
Great work E.O., yesterday I increase Benfotiamine from 500 mg to 1000 mg and I experienced many of the side effects You mention here the symptoms subsided after I took NAC 600mg , the major difference in my protocol was the absence of CDP coline
that I was taking regularly and also the addition of a probiotic suppliment, so I will be adding potassium rich food and a mythyl door suppliment, thanks for sharing
appreciated 👍👍👍!!!
What is the NAC600?
@@larryestrada5418 NAC stands for N Acetyl L Cysteine, Cysteine is an amino acid with an Acetyl group attached to it for making it more bioavailable, 600 is for dose i.e. 600mg , it's a potent anti oxidant which is the rate limiting substance for the synthesis of Glutathione an endogenous anti oxidant present in every living cell of our body !!!
@@bhupendranath2010 Thank you for responding.
@@bhupendranath2010 thank you for the explanation. Good job
Thanks for sharing yours user experience, it helps, very many thanks to Dr Elliott, loooong live
Thank you 🙏
Melatonin helps to recycle GSSH to GSH and other products of oxidative stress. Probably could lower the paradoxical effect.
Take a high quality B COMPLEX and most of your risk will be gone. Add some magnesium, some "low salt" (i.e. potassium salt) and high-selenium foods and you're set.
@@mercychesed4104 I was told to never take calcium.
@@mercychesed4104 IT WAS DR ERIC BERG.
@@mercychesed4104 how did you come to understand this? And who advised you along the way?
@@mercychesed4104 since everyone is different you mean it's the only combination that works for you 🤔
@@mercychesed4104 this info was gratefully received - even if I don’t know much about all this. Thank you.
Also, we need glutathione to absorb copper and we need copper to make DAO and MAO as well as many neurotransmiters. Sulfur depletes copper and in that case it will deplete all of the above, so it will cause histamine problems as well as other problems.
Copper is also needed for thiamine absorption.
HTH!
Thanks for sharing!
@@tiima98.93 You are welcome. Just keep in mind that you also need molybdenum to incorporate copper inyo ceruloplasmin. Copper deficiency is rare and molybdenum very very often.
@@SokTamo Yess i've ordered molybdenum already ! zinc and NAC alone helped histamine issues, molybdenum should regulate copper better :)
@@tiima98.93 nice! Its always better to get vitamins and minerals from food, especially zinc, calcium, magnesium. They all can, as supplements, interacts with other minerals, especially with molybdenum.
About molydenum, its always better to take sodium molybdate over glycinate. But anything is better than nothing.
@@SokTamo yes true. I only take low dose zinc (10 mg) to avoid those imbalances :) copper from dark chocolate. and thanks for the molybdenum recommendation, that's the one I ordered ! ionic sodium molybdate
B1 100mg twice morning took two days to go from wheel chair and barely stepping forward to walking three miles in one day . Parkinson’s med new start didn’t do anything. Try it as it could change your walking ability.
😊
Thank you for the information Elliot.
What is considered a high dosage for a male and female of .Benfotamine ?
Also can you recommend the best mineral or formulation containing all the necessary supporting minerals including magnesium potassium etc pls ..
We have to keep in mind that in food intake potassium is also present.
so what is the ideal potassium necessary for an active person and say awfully paralyzed person ?
Suddenly taking benfotamine has become scary .. .after listening to the complex orixesing and requirements to enable its efficacy..
What would be a safe dosage ..for someone with neurological issues ?
Checking electrolytes is not easy for general folks ..
but the symptoms you explained us helpful.
Kesol 15 is a liquid ..can you equate evaluate in tsp how much 1 tsp is really in terms of mg?
also which is the best form of glutathione older folks can use to supplement ?
Is 400mg benforamine for a paralyzed male high ?
My IBS-D, anxiety and panic have been greatly improved taking B1 (thiamine mononitrate) 500 mg twice a day most days. I plan to taper off and take a few times a week and see if anything changes. I took methylated b complex for a couple of weeks but started to feel edgy so I stopped that. I always take 400 mg of magnesium glycinate daily for several years. I also use lots of pink salt.
I do believe in B vitamins as therapy for many issues. I was even told by MD to take B1 when I had covid. Love your channel.
Generally, they say you continue high dose until your symptoms are gone completely, or are where you are comfortable with them remaining. Once you taper down to a maintenance level, you will, at least as I understand it, stop seeing improvement (but shouldn't see a decline, either.) This is particularly the case with neurological or brain-based symptoms that require saturation in the brain (which takes consistent high dosing over a long time, though TTFD can potentially shortcut it.)
You have a phenomenal doctor then. Counted yourself BLESSED! Happy for you!! :)
WhT all is in pink salt??
@@burningbright5039 Himalayan pink salt ; sodium chloride with trace presence of calcium , iron, zinc, chromium, magnesium, and sulfate- easy to get at your regular grocery store in a large container - look up benefits, try- buy accordingly.
hows it going now?
Why m in getting headache and more anxiety taking thaimine ? I am b1 deficient though
Major skin burning and stress through body. Took b1 for 6 months but ignored side effects till it's really scary. Nice to see the vid but when he said here are all the things to make sure glutathione status is good before you go on to a therapeutic dose made me happy(for the info) but also upset. Trying to add a bunch of new supplements in this poor state is stressful.
@@jbeauty4150 I'm glad I take benfotiamine b1 and 1/8 of an active b complex (super B-Complex) most days at least by Igennus but balancing not taking too much is still incredibly difficult. Daily scared I'm gonna screw up the amounts although I know I'd be screwed if I stop taking it all together. I have ME/CFS so I'm probably different than most. Really wish there was better testing and someone smart I could talk through regularly but it is what it is. I do wonder why my body doesn't make/absorb enough in the first place is the real question. I will say I've found active b complex way better than inactive b complex.
@@jbeauty4150 I did mention the one I take. It's called Super B Complex by Igennus. I get it off Amazon and cut the pills into 1/8 tablets. I'm confused though, you took 300-600 mg of benfo daily with no affect but feel worse after a b-complex? So it's the other b-vitamins giving you side effects? Like I said, I felt like sh*t after taking a regular non active b complex so maybe that's it.
@@jbeauty4150 I think we're all different so I'd go with your gut. B-comp makes me shaky and weak if I take too much but I wouldn't be able to move w/out it so even if there are some bad side effects it may be worth it. Only other thing I'd say is I'm not convinced mega dosing is a great idea. Especially w/out more proof it works. I'm convinced that my body won't just adjust to it. Sorry I can't be more helpful. If I was smarter, I'd already have fixed my own issues.
@@jbeauty4150 You're welcome. In my terrible state one of the few things I find meaningful in my life is trying to help others less experienced navigate this sh*t. I'll just say that since benfotiamine b1 is fat soluable(unlike other b vitamins), I believe it builds up and doesn't HAVE to be a daily thing. I started around 75 mg for a few months and now I'm down to only like 15mg per day. Agree, you might have just been depleted. Although taking a lot uses up the other b vitamins which is why I can't take any b1 without a little b complex as well nowadays. Lastly, not to be too pushy, but you probably want ACTIVE B vitamins as regular b complex really did not help me.
way too much in the weeds. Just need to do what to do since B1 gives me gas/bloating and can't sleep with it. In the morning for some reason is a drop better for some reason. When I take a B complex the symptoms are worse
Level 10 Brilliant. Elliot is a genius for this type of information. Bless him!
Wow, you are a blessing. Practically, everything you’re covering I experienced recently after increasing my B1. It was causing depression, anxiety and the whole gambit. Wow. Thank you!!
Can the negative side affects be detox reactions? If the mitochondria starts working it and the cell may be dumping out toxins
I too high dose and felt very weird indeed maybe slight blue lips made me feel anxious about toxicity damage
Update?
I'd just like to post a warning for anyone looking to boost their methylation:
Consider every option over SAMe (and add Creatine to the list of considerations since it is probably the most effective methylation booster.) SAMe is a functional SSRI, even though you don't need a prescription for it. I had full on SSRI withdrawal symptoms, including electric zaps, after coming off of it, as well as post-SSRI sexual dysfunction syndrome that took quite a while to resolve (and it's my understanding this could become permanent in some people.) Please be careful with it. Do a lot of research. (I was only on 400mg a day, too, which is considered a low dose.)
Thank you for the video, though, Elliot. It's nice to have a list of important cofactors in one place for reference, and the Riboflavin/Niacin influences were new to me. I've only used Benfotiamine so far (to immediate and optimistic results,) but am looking to add TTFD to address (at least more quickly?) the stubborn mental symptoms. This information was helpful for my preparation.
That is actually very interesting as I take Lexapro. I am also taking methycobalamin 100mcg per day, 400mcg Calcium-L-Methylfolate, 5g Creatinemonohydrat, 50mg TMG/Betaine and 10mg CDP-Choline daily alongside it.. is this dangerous? Because I read that SSRI deplete the body of B12 and Folate
Are they even strong enough as Methyldonators to interact with Escitaloprame? I make sure that I don't take them together but with at least 2 hours in between
What do you think it was, specific to you, that led to SAMe causing such a negative reaction?
Also, if TTFD can deplete SAMe, what other option would you recommend to reverse that?
I have alopecia, including no eyelashes, no eyebrows, no nasal hairs. After using samE 200-400 mg for fibromyalgia, I was at least able to grow eyelashes, which are very protective of the eyes and a few eyebrows, at least enough to color in.
The only brands that seem to benefit were Life Extension Foundation, and Nature Made. It also helps my fibromyalgia, and I had no problem with it.
@@briandrescher5663 Might not be anything specific to me. There is an entire forum board I found, after the fact, with hundreds of testimonials to similar experience with SAMe (though most were on higher dosage than I.) I certainly have nervous system issues induced by B6 toxicity (multivitamin dose over a long time,) that could have made me more sensitive to SAMe's modulatory effects. Anhedonia is definitely a common side effect of SAMe, however, as well as with other SSRIs. It's worth noting that just because something isn't prescription, doesn't necessarily mean it is weaker. Take Quercetin, for instance. They still haven't decided (in studies) on how effective the mast cell stabilizing properties are, but I know that for myself, and many others, it's probably the most effective antihistamine I've ever tried (through its mcs properties.) And a number of studies indicate SAMe working for patients who otherwise do not respond well to common SSRIs, either speaking to a different mechanism of action or increased efficacy in responders.
So creatine over SAMe?
Very enlightening information. I was in the ER several years ago with heart attack symptoms. I did not have a heart attack per se and the symptoms might have been caused by critical deficiencies. Lab analysis of my serum mineral levels revealed my potassium level was within 2% of the danger threshold for heart complications. This was a very perplexing finding since my diet included adequate sources of potassium. Since then I added potassium supplementation and have been ok (I think). It never occurred to me the root cause might have been B-1 deficiency. Recently I had to discontinue gabapentin and decided to try benfotiamine. I experienced profound improvements not only with nerve pain, but also with my carbohydrate metabolism. The scope and magnitude of these improvements leaves me wondering if the root cause of most of my health issues has been B-1 deficiency all along. It's going to be part of my routine lab panels from now on.
How is your metabolism now I am having same issues I take Benfortamine but do not know if it's the correct one, because I don't feel too much of a difference! Can you please share what brand and dosage are you taking. Thank you so much in advance!
Need magnesium to absorb potassium
So I don’t have this problem with thiamine, but sometimes magnesium will cause me muscle spasms and tension, and give me insomnia. I’ve found changing the type of magnesium and how it’s absorbed helps- citrate, and through the skin or a drink works better than other forms in pill form. Having potassium and B1 also helps me absorb magnesium better I think. Funny how we all work just a little bit differently!
Vitamin A toxicity underlies a lot of these problems. Molybdinum and thiamine both support the detoxification pathways the body needs to get rid of retinoic acid. Retinoic acid also depletes them, so supplementing with them will shore up these detox pathways.
Do you believe vitamin A is an antinutrient?
@Sling Blade Do a web search for Greg Genereux and Vitamin A toxicity. He's got a blog and several books you can download for free and read. The primary one where he lays out the case for it not being a vitamin but a toxin that is causing all kinds of auto-immune problems is called Extinguishing the Fires of Hell. There's a link right at the top of his blog, My Books, where you can find it.
I assume you mean vit A toxicity from synthetic supplements?
If vitamin A is a toxin why all hunters crave organ and liver meat.
Why does the Ecological Formulas Ttfd has calcium and phosphorus in it?
Also benfotiamine contain a phosphorus molecule in it and ttfd does not. So is it to compensate the lacking phosphorus that calcium and phosphorus is added to the ecological formulas ttfd?
I ordered Ecological Formulas TTFD recently, and although it was advertised as containing calcium / phosphorus, when it arrived, those ingredients were no longer included. Just TTFD, Microcrystaline Cellulose, Gelatin(capsule), Magnesium Stearate, Silicone Dioxide. Perhaps contact them to confirm. I suspect they have updated their formula.
@@rosstituteuk Thanks for the info, depending on availability this may help people. Thiamax is easy to get still so I'd trust it.
Genius.. This video filled in all the blanks I had about Thiamine and it's derivatives. THANK YOU!!
I’ve worked so hard to rebuild my health, I started benfotamine recently and I’ve felt like absolute crap over the last week.
Same here with ttdf
@@ratoncitoification yeah I’ve tried twice now and each time it totally wipes out all the gains I’ve made in the last 12 months.
I tried everything to alleviate it, everything eo suggests and it did nothing.
It’s not worth it imo
Honestly, I found this video to be so overwhelming. I have POTS and I thought I was doing the right thing by taking 1,800 mgs of Thiamine. But, there are clearly so many things that can go wrong, and so many things that need to be done to adjust for this high dose. I am on disability and can’t afford all of the supplements needed just to address the effects of high dose B1.
What I don’t understand is, if high dose B1 is so curative then why does it cause such significant imbalances? It seems like the body is struggling to handle such a high dose. If it helps so much then why does it throw things so far out of balance?
Same
From what I’ve learned, is that you should gradually go higher and that the adjustment and reaction period is about 1 week, for every time you increase. Unfortunately low doses that we don’t feel, will not help people that are deficient and even more for those of us that are dependent.
I believe the reason it helps but also causes other issues is because the body doesn’t actually need that quantity of thiamine, it just has an issue using the thiamine you get. So to remedy the absorption issue you take a mega dose. This doesn’t address the underlying cause of why your body struggles to use thiamine, though! The body isn’t meant to intake such high quantities, so while this solutions works to overcome the absorption issue, it messes with those absorption pathways that other nutrients need to use.
The B vitamins, like the fat-soluble vitamins (A, D, K, E), have such tremendous and complex effects in every system throughout the body. Many of these vitamins act more like hormones than mere nutrients. That is to say they are master molecules that direct and regulate other nutrients. As for the side effects of high dose B1, it shouldn't be too expensive. Mainly, all you need to add in is some inexpensive mineral supplements like magnesium and electrolytes. Most multivitamins would cover the main minerals.
In addition to high dose of thiamine you also need high dose of magnesium and potassium, selenium (just couple of Brazil nuts) and vitamin D with K2 along with a balanced diet. Jesus bore 39 stripes for all our diseases. All the deficiencies in our bodies he took it upon His body so that by His stripes you are healed. I pray the healing power of Jesus touch you and heal you of POTS and any disability and deficiencies in your body in Jesus name. Amen
I slowly started this.. and slowly highten the dose.. no probs here, just positive effects.(Chronic Lyme and co) Thank You for this info about thiamine.. its greatly improved my life in ALL ways❣️😌👌🏼.. much Love 👋🏼☺️🇸🇪
Increase your vit c for Lyme...
Upto 60 gm a day
When you say “low dose theramine Hcl” is that low as in mg in the single digits? Or more like 50mg?
well 50 is like 4000% of the daily amount isnt it so i doubt that goes along with what he said but who knows you can try it if you want
50 to 100 mg is okay, you can definitely increase that if you don't feel anything. I take benfotiamine because the 50mg in the multi-vitamin wasn't doing anything.
@@Phasma6969 what about the thiamine in the b complex?
@@DavidsonLoops The idea of a therapeutic dose is >150mg B1 HCL, so yeah the thiamine in the B-Complex would count towards that value. However, you would want more than what most B-Complex provide, hence therapeutic dose.
@@Phasma6969 If we were talking about the therapeutic dose we'd be talking about TTFD not the complex or multivitamins, this is about the prep
Elliot, appreciate all your work. These are great information. Wishing you a loooooong & happy life.
I’m pretty savvy with vitamin supplements herbs etc.… I’ve been doing this for a while and methylation has got to be one of the most confusing and complicated conditions of all of them. everything you’re saying sounds very familiar like I know I could understand it, but unraveling the puzzle takes me in so many different directions I can’t really put it together well. I do have a lot of good information from my years of trying different things and a pretty good lock on my symptoms. Wish I could get a consult with you! I would definitely know what to do if pointed in the right direction, I have all the supplements! Lol
So is this a college class in chemistry. I got a little of it but I also had flash backs of college biology. Got a better understanding with the comments.
1 John 1:9 If we confess our sins He is faithful and just to forgive us and cleanse us from all unrighteousness 💝
And this relates to taking vitamins how? Why don't you find a nice, religious channel? God helps those who help themselves.
Amen.
Yes, but Jesus met people where they were at. He put things into the proper context. And he gave us the Holy Spirit to have discernment to know when, where and how to proceed. We are to find those who have the gifts, talents, and message for a situation.
Amen! ~ Ty for sharing.
💖Anytime/Anywhere💖
God put his breath of life in you.
What do you think about lithium orotate? Would be interested to know if it plays a part in methylation.
I do orotate or very low dose carbonate. Micah Coffey mentions lithium.
I am wondering if I can do this,suffering with severe M.E ,chemical intolerance,MCAS,histamine intolerance,malabsorption.even taking multivits I react very badly
Me too all of it!
What are the symptoms if you have achieved Thiamine saturation and continue to take larger doses?
Great question! Have you found the answer to this. I'm a bit skeptical of taking high doses for a longer period of time and think this could lead to further imbalances.
@@cavallopazzo340 I have not received an answer to this question unfortunately.
Please correct me if I'm wrong - but might thiamine supplementation increase the amount of Krebs-cycle intermediates there are in a urinary organic acids test if the body has excess precursors (e.g. thiamine) kickstarting "more Krebs-cycles"? For example, elevated citric acid and alpha-ketoglutarate follow soon after thiamine in the same cycle. Or would excess of those in urine indicate a lack of b2, b5, etc.? Wondering if there is any significance if consecutive Krebs-cycle intermediates are found elevated in urine.
Very very helpful. Explains so much of my difficulties and what to watch when raising benfotiamine. THANK YOU.
For what reason did you take thiamine?
This is SO complicated!!! Why would one take TTDF if they can get the same benefits from other types of thiamine?
Some people will only see improvements on TTFD
So you're saying that ppl w methylation problems (i.e. cannot process sulfur in foods) should take sam-e with TTFD form of thiamine?? Or take molybdenum... or just try another form of thiamine that doesn't have sulfur bonds? 🤔😲😪
The biological form of the molybdenum atom is an organic molecule known as the molybdenum cofactor (Moco) present in the active site of Moco-containing enzymes (molybdoenzymes). In humans, molybdenum is known to function as a cofactor for four enzymes.
One of them is Sulfite oxidase. This enzyme catalyses the transformation of sulfite to sulfate, a reaction that is necessary for the metabolism of sulfur-containing amino acids (methionine and cysteine).
You also need methylated B-Vitamins especially methyltetrahydrofolate or the methylated form of folate, or else you will have problems with methylation. You need to get tested to discover if you have the polymorphism associated with poor methylation. There are a few, here is a link below.
www.apoe4.info/wiki/Methylation
Source for molybdenum: LPI Oregon State; lpi.oregonstate.edu/mic/minerals/molybdenum
Careful with SAM-e, you want to fix multiple steps in methylation too, not just dose up on SAM-e. There is such a thing a over-methylation which is said to have effects like a stimulant-type drug.
What Elliot suggests is to increase and resolve methylation or potential methylation issues first and then begin TTFD and taper it UP till you reach the therapeutic dose, the dose is incredibly variable and depends on your degree of metabolic impairment. You can find this out with an RBC Transketolase test or OAT (organic acids test).
More information can be found here too. www.ncbi.nlm.nih.gov/pmc/articles/PMC3913508/
Biomarkers here, this also includes biomarkers and SNPs for methylation amongst other markers; www.apoe4.info/wiki/Biomarkers
@@Phasma6969 amazing info! so methylated b12 and folate, molybdenum, glutathione, and SAM-e BEFORE high dose TTFD... would u recommend allithiamine? cant find ttfd..........
@@Ravenswhisper Probably not, you can check for that if the copper is bound or free. Free copper isnt usable in the body as far as I know? 500mcg is a lot but 200mcg sounds fine
i have a question. taking a b complex, do I need to get mega doses of all b vitamins, or it's just 100% of the RDA for all of them? and there's any specific brands recommended? thank you very much
I have the same question.
I had the worst stomach cramps in my life when I started B1 (benfotiamine), I can't walk upright for a more than a week. The cramps lasted 3 weeks. It did reverse most of my issues. Just sharing my experience.
Was it worth it in the end?
And what do you think caused the cramping?
@@zoezzzarko1117 worth it absolutely. Well, what do I think based on my absolute pure guess, I had slow motility and GI issues. So probably B1 restore these functions and make my GI tract hyperactive/adapted too quickly causing the cramps.
@@AbirafdiRadityaPutra ahhhhhhh ok yes. I get what you are saying now. Thank you for letting me know more detail... I appreciate it.
Did you stop taking the Thiamine when it helped you... or did you just lower the dose?
@@zoezzzarko1117 I am now off thiamine. I tried stop taking it multiple times, but my issues came back. Took me around 8 months to be able to stop taking it without my issues (GI and appetite issues) coming back.
@@AbirafdiRadityaPutra thank you for the guidance 🙏
I have been on keto and 16:8 IF for over a year and don't take any supplements. Now I get shortness of breath on and off and wondering if I should add b1 like benfotiamine?,maybe some imbalance I developed?
I would say yes.
This happened to me after 4 months of keto. Also check copper levels as keto is zinc rich.
Three days so far taking 1.2g sulbutiamine. So far so good. First two days, felt good for 2-3 hours afterwards, gradually tending into a kind of excess fatigue (I'm dealing with some chronic fatigue, migraines, insomnia). Yesterday I took a lot more multivitamins, humic/fulvic acid, and other supplements with it, this time mixed into my protein smoothie and just before some exercise; definitely felt better throughout the afternoon and evening.
It's early in, but I'm hoping this will help "reset" something in my metabolism.
Hope you're doing better
Increase vit c and salt
How's the status?
Hey folks. Simple update - I don't remember the details too well. I think I went a couple of weeks on this, 2-3 weeks. Not sure now. No definite results, though if I had to guess, I'd go with a subtle body intuition says it was good, but not a crucial factor for me.
Overall I have made some recovery in the interim, and still a ways to go. I've battled a serious tooth infection, went keto for a few weeks and cut back severely on sugars for several months. I don't eat a conventional diet anyways in teens of processed food, almost entirely eggs, meat, vegetables, and protein shakes (organic milk, cream, grassfed whey concentrate, no artificial sweeteners etc).
I got more regular home workouts, made an infrared sauna last June, and did get fairly regular with cold tub dips.
I still had a lot of serious health challenges along the way, but definitely improved this fall in reduction in migraines & headaches, and slightly improved consistency of sleep - still consistently below normal levels.
If you want to know more just ask, maybe check out my RUclips channel, mostly just kittens for now but I'm thinking of starting to vlog on the healing journey.
@@MikePeiman I used to get migraines often until I cut out grains. Also I’ve just discovered how “the healthy” foods I was eating as keto like greens, nuts, buckwheat etc contain oxalates and my body doesn’t get rid of that buildup and causes major pain. I’m now working through the dumping of them and have just started thiamine today to hopefully help with other issues. Good luck with your health improvement.
After individually trying all B vitamins (B1, B2, B3, B5, B6, B7, B9, B12), the only B vitamin which started to resolve my health issues is 100mg B1 thiamine HCL, Does that mean I can get away with low dose B1 (100mg only) to resolve my issues without the need to go higher thus avoiding unpleasant high dose symptoms?
Did you stop taking b complex and taking only b1 ?
Hey Elliot,
I've read somewhere that thiamine hydrochloride should not be consumed with citrates. Would it hinder absorption or is it a health risk? If so, how far apart should the consumption of these supplements be?
I'm asking because I supplement with both potassium and magnesium citrate on a regular basis.
Thanks.
I am also interested because I take thiamine hcl and magnesium citrate
also interested
Interested to;)
@EO Nutrition . . we have a question for you!
I was told to get of the magnesium citrate because it scratches the intestinal wall, causing irritation.
¿Debo tomar agua de botellas de cristal en vez de las que van en recipientes plásticos? Gracias!
BCN
Any form of Thiamine gives me a lot of energy - but also causes sleeping problems. I can't sleep for more than 2 hours at night.
I can't turn my brain off while supplementing Thiamine.
The only thing that can counteract Thiamine for me would be Inositol and Alpha GPC (acetylcholine).
Magnesium helps, but not as much...
I will proceed to watching the video now.
Thank you Elliot
@16:38 he describes your symptoms
Inositol did nothing to shut my brain off, when I took 16 gram a day... without taking mega dose of anything
Does thiamine give you sleeping problems even when taken in the morning?
@@ChristianChase7 Yes:/
@@WS-ij4ey I dont get it though. I have all the symptoms of an overmethylator, yet he says the SAMe would work for my Thiamine side effects.
I'm confused :(
Can you please also talk to the lay person after you use a medical word follow up with a short meaning after it. That would help the understanding .
After learning about thiamine I was sure I am so deficient in it. In March 2020, I got really sick from the foods I ate ( refined carbs, Powerades, fruit juices) very high in carbs. Until Jan 2022 I had no Idea what is going on. I have severe sinusitis, Bloating specially from Salicylates & phenols (can't even have any veg & fruit without burping) which was causing Esphogas damage & I was on pantoprazole for it. Other issues like tingling & numbness of hands & feets, I recently noticed blood sugar was at 7.2 in last blood test which was moving towards prediabetic, low energy, brain fog, blurry Vision etc & etc. Went to ENT twice , allergy test nothing helped.
It impacted my life so much that I used to be really fit, healthy, muscler body but I couldn't understand why on high carb/ calorie diet my weight was not going up but was going down continuously. I almost lost 9kg in 1.5 year. All the blood tests, Sibo, H Pylori test was Ok. So I left the salicylates & phenols completely out of my diet & felt better with bloating & sinus issues.
But that's not the long term plan.
So I keep digging out until I found Elliot's & Dr Berg's videos on B1.
I can confidently say that BENFOTIAMINE & TTFD ( THIAMAX) will give you issues when you first start them. The reason is that your thiamine levels are very very low and BENFOTIAMINE has BENZOYL in it. What it means that When thiamine is very low Benzoic acid to hippurate conjugation is inhibited because thiamine is required for normal conjugation. Once you keep taking it for week or 2 & you will build up thiamine in your body this process with normalized.
Same with THIAMAX it has Sulphites in it which actually depletes thiamine. It means your body already had literally no thiamine & you adding sulphites in it & definitely it will give you some paradoxical symptoms until thiamine start kicking in.
On the other hand, Thiamine HCL doesn't have any of it. So people tend to absorb it symptom free. But problem is that it is water souble & eliminated in urine in excess.
If you want to build the Thiamine levels better to take Fat Souble one so that body can store it if in excess.
I started with Thiamine HCL for 2 weeks & now on Benfotiamine 1500mg & yes I am having Paradoxical symptoms but I am pretty sure once Thiamine level builds up in body it will be All right.
I will update how it goes
Question. So you take 1500 mgs of bentothiamine now? How much HCL were you taking? Do you take or do anything to alleviate the horrible symptoms?
@@misterketofast3855 B1 deficiency will lead you to numerous diseases such as diabetes, Dementia, Acid Reflux or bloating etc etc. For example if Acid Reflux don't stop it will slowly progress to barrets esphogus. I only named few, since May 2020 I got too sick from very fit & healthy. I had lot of issues first started with sneezing, runny nose then it turns to Severe Sinusitis. Excessive bloating which was causing Esphogas damage and I was on pantoprazole 40mg. But still get the bloating. I lost 7kg muscles over 20 months & 10kg in total weight.
The problem is now a days we concentrate on Macro nutrients( Protein, Fat, Carbs) but not on micro nutrients(Vitamins & minerals) which are required to digest the food.
For example- if you eat refined carbs it is pretty much simple carbs with very little vitamines in it. So over the time when you do that, you deplete vitamins out of your body. Specially Magnesium & B1 Thiamine & YOU become deficient. The more deficient you get less the foods you will tolerate.
I have done too many blood tests, SIBO, Allegry test, seen ENT nothing helped. But I kept digging out the reason behind all the sudden problems. In Feb 2022 I started with Thiamine HCL with 800mg a day to 1500mg. I seen improvement in Acid Reflux. Then 2nd week i stared 600mg benfotiamine which is fat souble it pretty much stopped the acid reflux & bloating. My mind is clearing as well. I have tinnitus which is nerve damage in ear started getting lot better. I am now on 1800mg benfotiamine & 1200mg thiamine HCL.
For complete healing I think I should must supplement it for 6 months. This vitamin is by far the most important vitamin in our body as per my research which get depleted by too many factors and RDA is only 1.2mg.
In modern diet it should be supplemented 100mg for even healthy person to keep the balance of it for proper function of its cofactors
thanks for the information. i wish you the best with your healing.
@@GurvinderSingh-vg1pq how is everything going now with your progress?
@@GurvinderSingh-vg1pq Interesting you say all that because I switched to Benfotiamine because I have neuropathy and TTFD was still effective but I figure since Benfotiamine is. Fat soluble it be more beneficial I’m still having slight paradoxical reaction 2.5 weeks after starting but I’m getting used to it.
I was taking bentfotiamine which I thought wasn’t causing any problems. Then I started taking sulbutamine as well and it caused really poor and irritable mood so I quit taking it immediately. Now I’ve realized I have been having the same problem with Benfotiamine and didn’t realize it so I’m just going to stop taking it. If I add all these other supplements to be able to take this, then I’m just going to find I’m intolerant to those as well.
There are many moving parts here. Seems potentially a train wreck for all but the most savvy. IN terms of forms, is there a middle ground between most potent/bioavailable and semi-useless like thiamine Hcl?
Do you find B1 HCL useless? Is TTFD a better source? Why?
@@grinch30 Some people require massive doses of B1 HCL to gain any benefit, the other B1 variants are more bio-available such as benfotiamine for peripheral tissue. I haven't read up on the mechanism for benfotiamine so I'm uncertain if it can get past the blood brain barrier but TTFD for sure can. Neurological symptoms should be treated with magnesium, b-complex and TTFD.
Yes, that is what I am thinking. I have very poor detoxification, have a histamine disorder and do not have good methylation or glutathione. I wanted to try this but it just seems so risky. I am going to stick with the liver/organ caps (when I can choke them down, oxalates have shredded my esophagus). Carnivore has helped me a lot; but have a little bit of bleeding gums and still have a "mast cell" disorder. Gonna try small doses of vit c; and homeopathy has been helping me with detox (like amazingly so). I think I will stick with those things that do not cause me serious side effects. I have experienced enough scary things due to all this; and I am finally more stable. I wish to not have more side effects. Oxalate dumping has been severe at times.... not fun.
@@lr1732 best to go slow .
Have you tried hcl and digestive enzymes.
@@lr1732 How're you doing nowdays? Better? Your symptons sound like mine.
I have been taking thiamine for several months. I cannot be without it. It makes a huge difference in how I feel. It helps my eye pain, fatigue, reactions to food, etc. The only problem is that I get so hungry and crave so many carbs. If i go a day without it I feel full and dont overeat. If i take it, even 100mg i get so hungry all day and have major cravings. Any thoughts on the excess hunger? Thanks so much! Keep up the great work!
Excessive hunger seems good, considering most people with a thiamine deficiency feel the exact opposite.
@@Josue-xd5ru Thank you for the reply! That is interesting. I guess for so many years I was not hungry at all. Now to feel hungry constantly is a very new feeling. Thank you!
Did it increase your weight?
Und did improve your digestion?
Cause I suffer from that
Please replay
Greetings
Eat whole foods plant based see if it helps. Complex carbs and clean proteins like legumes, lentils, etc.
Excessive hunger is a symptom of not getting enough high nutrient foods. Instead of eating processed nutrient devoid man-made foods, eat fatty meats, animal organs, butter, eggs. Our diets should consist mainly of animal foods and small amounts of well cooked veggies like broccoli, asparagus, Brussels sprouts, cabbage, cauliflower, etc. Avoid starchy high carb veggies; have those sparingly. Fruit very rarely (except avocado). You will notice your hunger go down as your body gets nourished.
Hope someone can help me. I'm b1 deficient. Can I start on 100mg allithiamine? Or does it have to be 50mg? I'm suffering a lot. Maybe 100mg split between 2 doses of 50mg? Along with magnesium and a b complex. Just hoping someone can clarify as I want to start it without mistakes. Also b complex incudes b1 and a decent one is high dose too! So confused. How do I know if I have paradox when doing it?
When in doubt, go low & slow.
I started at 25mg on TTFD (ThiaMax) and it knocked me off my perch for a few hours.
Also, just be sure to take at least one of the co-factors Elliot mentioned in the video ... namely Magnesium.
Hope you''re doing better if you've already begun your Thiamine therapy.
I've been taking it for a week mainly to stop tingling in my feet and fingers and my tinnitus is through the roof, any connection there?
Check b12 deficiency
I will be trying your
Thiamax soon , so this
Is all very useful info.
Thank you.
Brother you summed up everything I was researching today. Niacin NAC glycine glutathione thiamine Babin geberal and added rest of picture
Bss really need balance
ppl fix one thing with Bx than after 2 years a problem of second deficiency
Histamine WOW I love this channel already!!!
Fascinating video thank you. I'm a nurse so I think that helped me understand it all :D you explained it very well though 👏🏼 Im megadosing to hopefully help my persistent methane dominant SIBO. I feel brighter and able to concentrate better so far. Helping my constipation and think I have small amounts of die off in stool🎉
Did it help you ?
Update?
@@acinamatata6342I'm guessing you have or had sibo too and we're considering trying high dose Thiamine? Did you try it & did it help?
Wow I had all the symptoms for electrolytes except for water retention. Cronometer app showed I am very low on potassium intake. I am taking REMAG for better magnesium absorption.
Elliott, this is such a special channel!
What altenatives are there to molybdenum (MB)?
I take various b1's, magnesiums, (and generic sacro b for ibs). I'm becoming allergic to the garlic smell of my own self and the smell of many foods, even with daily showers and deoderants. The MB seems to help for a while, but it becomes less effective over time and prolonged use seems to make my nails paper thin and easily damaged (Male).
didnt know that about molyb, maybe thats why he said dont go over a few hundred mcg. i feel that way about pentothenate, great effect but i cant sleep and my scalp got super dry
Eliot you are a gem sir. Thanks again for the education.
So I have this issue I believe after the v. It made this way worst and I started having sharp needle pains all over body. I did spectracell micronutrient test and I am deficient b12 folate zinc chromium selenium b6 b5 inositol. So I should take TTFD? It shows my thiamine levels above the deficiency level
Took 750mg for a few days then I started to feel too relaxed and now I’m on 500mg and feel much better
What brand and details please?
@@katiejon17 Brand: Life Extension
Name: Mega Benfotiamine 250mg
@@katiejon17 this supplement is a miracle cure for nerve function. I had blurry vison for about 2 months because of high blood sugar as I’m type 1 diabetic. I took 750mg the first day and the next morning my vision was crystal clear. I really couldn’t believe it.
How do you know if your body has methylation issues?
For me ttfd brings on a huge oxalate dump. A Good thing but I have to be careful. Not a problem with Hcl or Benfotiamine.
Interesting , so I am having issues. Do you use benfontamine instead of ttdf and titrate up?
@@debbicornell1 I would be interested to know the answer to this, too...
I take benfothiamine one small capsule a day a low dosage .
@@freemanmt Can you please tell me how low is a good dose to take? Thankyou very much!
It’s the dicalcium phosphate in the ttfd formula causing the oxalate dump not the thiamine itself.
The company use dicalcium phosphate when making ttfd for an filler for reasons I don’t understand
14:55 what is considered a good low dose of thiamine hcl ? Considering it’s not well absorbed maybe 250mg??
Ttfd can lower copper levels leading to premature grey hair and sleep issues.
Mechanism pls?
@@Byrial ttfd has sulfur and sulfur is a very strong chelator of copper.
@@sahdev520 right but is it significant? I eat a little bee pollen for copper ever day
Great info. I'm already ruling out 2 forms of thiamine as im extremely intolerant of sulfur /thiols. Ive been ovoiding methylated anything, too.
I used to supplement potassium before I used TTFD. After using TTFD for about a month, I tried supplementing potassium again but got headaches from it. I wonder if that was due to better retention of potassium from the thiamine
Yep, this is very common. It happened to me like this, also! I used to need a lot of potassium, now none
@@EONutrition HELLO MY DEAR. LOVE YOUR INSIGHT AND BRAIN OF KNOWLEDGE💯MAY YOU PLEASE KINDLY ADDRESS THE QUESTIONS ASKED BY YOUR VIEWERS PLEASE IN THE COMMENTS 🙏THANKS🙏
@@francenealexandre7904 I was wondering why he hasn't too, he's so informative; I want to see his replies. Sometimes you can't get all the answers from the videos.
@@francenealexandre7904 totally agree. Or some references to other vids that may answer some.
@@francenealexandre7904 There's no way he could possibly answer everyones question. That would be a full time job. 😆
Thank you for this. I was under much stress for a long period. BP shot up and sodium went to low so now that my sodium, magnesium are somewhat level. I’m unsure about taking thiamin? Thank you for any help.
Every time I try to take a Thiamine supplement it amplifies my sleep apnea. Anyone know what the reason for this could be?
I'm not sure, but UNfortified Nutritional yeast has all the B vitimins that are supposed to cure sleep apnea.
Make sure it is UNfortified, NOT fortified.
My B12 levels skyrocketed to 1200ish degrees. I only have three more pills in my bottle, but I want to stop taking it. Would I lose much if I take Thiamax with just magnesium?
any supplements i take now i dont take the really high dose ones. takes a lot of research to try and get the right level and interactions between different ones as you pointed out can be problematic . also one size does not fit all. so thanks for this video. still a bit of a minefield but better to be informed than have no idea about how they work
I took 100mg of b1 hcl for the first time then I felt so warm and can't tolerate warmth and little of dizziness . But the next day my mental health and energy improved I took b1 cause I had b12 b9 diffency so doctor said I mostly low in most b vitamins cause my gut is not ok . Any advice to tackle this problem
Since trying thiamine, I have been more reactive to having more allergic reactions
riboflavin 400+mg is supposed to help, spread out in the day. i take 100mg every meal and it helps a lot. heard b5 helps too but i only notice an effect at a dose that *also* dries out my scalp and keeps me from sleeping. maybe it has an effect at half that and i just didnt notice
After taking 100mg I felt energized, took more pills after a couple of hours and I had fatigue, took magnesium and eat bananas but it just made me numb. But after eating dinner I felt so good. But I started to notice various pops of synovial bubbles from my joints during movement and feel my muscles like jelly, maybe is my perception or my body is self-consuming.
EONutrition I've been dosing everything you've listed(except GSH) for almost 2 months now. I'm about to take the plunge. I will keep you posted.
How you getting on?
@@TheReminderChannnel I stopped two weeks ago. I think the NAC I was taking started moving something to the point of not being able to function. The thiol "thing" is a very real thing so if you decide to start playing with your metabolism start small and increase dosages incrementally.
Also, added garlic and onion into meals regularly along with the NAC. Going to give it another week before resuming. I will eventually start the TTFD I just do not know when.
@@anonymousguest9290 thanks buddy, hope it goes well 💪
@@anonymousguest9290 following ;)
@@anonymousguest9290 check yourself for mercury
I heard from another person on here say that taking supplemental magnesium in people who are on Valsartan with Hct for high blood pressure,.. could cause heart failure,,is this true...please help cause I want to take magnesium...
Glad I watched this.. I have G6PD deficiency (genetic) and wondered if it would be safe for me to supplement large doses of B1?
Excellent presentation thank you for sharing this very knowledgeable healthy information
I have been trying thiamine hcl (200mg) day 3 and I have had body aches and knee pain. Already supplementing magnesium and a b complex (dont have potassium available to me just yet). Anyone else experience this or have advice? At the moment it feels like the thiamine is inflammatory and I am not sure if I should continue on
Make sure you have a magnesium supplement with high bioavailability, such as malate, glycinate, etc. As for potassium try to get that mainly from your diet.
I would do the following changes.
1. Replace thiamine hcl with benfotiamine / thiamine di phosphate (fat soluble thiamine ) and start with 150mg x 2/day in divided doses and cosupplement with a full spectrum coenzymayed methylayed B complex, magnesium 450mg / day (preferably magnesium citrate) and some supp potassium like potassium magnesium citrate upto 480 mg in divided doses.
Thiamine will increase demand for other B vitamins, Mg, K and also antioxidant recycling , so additionally supplementing with R-ALA, and Vit C might help as R-ALA also plays role in energy metabolism, is a universal antioxidant & can recycle Vit C. However, R-ALA also works in conjunction with B vitamins & Mg.
Further, Mg is necessary to regulate retention of K along with other B vitamins & Vit C.
Hope this helps ?!
@@sgtaneja thankyou , this helped me but what is R- ALA . Thankyou .
@@nancysmith-baker3827 The natural R variant/isomer of -Alpha Lipoic Acid which is more bioavbl.
@@sgtaneja Thankyou so much . I take that .
I've been taking Benfotiamine and am now taking sulbutiamine... now I am wondering if TTFD ( just received a bottle of ThiaMega and ThiAssist) is toxic?
Are there any other functional nutrion practitioners that can and will work with his type of protocol? Elliot is not accepting new clients, but doing this on my own seems dicey as my paradoxical reactions are severe. Anyone know of other practitioners? Thanks!
Agree. For me, I want to treat my daughter with thiamine but feels very irresponsible when my best guesses produce a paradoxical reaction ☹
@@davidthompson7344 I found what has been the most safe and responsible action has been to work with a qualified and skillful acupuncturist. I was indeed far too sensitive to consume B vitamins at all- so I had to address my extreme reactivity first. It was costly, but it's made all the difference in the world. Truly, I am finally improving because of this decision.
I discussed with her my situation and she agreed I needed urgent intensive treatment. So, I went 3-4 times a week for the first 3 weeks. Sounds like alot, and it was. But each week I started to gradually improve. After 2 months of intensive treatments 3x a week, I am now down to 2x a week and am doing much better. The difference has been incredible. I can eat more foods and can now handle taking supplements, which in the beginning I could not. Now I can take b vitamins, but in gentle doses. I take a multi and a food based b vitamin daily, with a break from the b ever couple of days so as to not trigger a histamine reaction.
But for me, this was the way. Consistent acupuncture and Chinese medicine from a reputable TCM doctor. I also started to practice a reputable Qi Gong style with this same doctor from her online school, and I have improved even quicker since beginning this. It sounds too good to be true, but it's real. Her school is Qi Dragon School if you are interested for your daughter. Doing this practice daily has helped me so much. The first weeks I had to do everything in bed and just using my imagination, because I was too fatigued to do it with my physical body. Now, 2 months later, I am doing half of the practice standing up! I do sit and lay down if I need to, but the improvement is real and visible. My complexion is improving, my mood, and my function all returning to normal. People say Qi Gong can heal the body, but now I am a believer. It is giving me my life back after years of chronic terrible illness and poor help from the western medical complex.
Hope this helps you and your daughter. Healing is possible, the body wants to recover. Heroic treatments like the vitamin B method I think can absolutely work for some. But if to reactive, depleted, or sensitive- I think it can be very hazardous. Healing energy your way🖖
@@jbeauty4150 I responded to davidthompson7344, check that out. Hope it helps you!
I started taking 1500mg for 3 days and not sure if side effects is eye twitching, head pressure? Is that normal? I’m doing to go down now
Yes I’ve had the same side effects
That is a huge dose!!! I take 25 mgs and no side effects. It works well for me. Will go up at some point, but not more than 50mgs probably.
so 30 pills of 50 mg ttfd ????
Okay this is what happened to me and was not able to bounce back quickly. I got to scared and backed off. Months later took 1 dose of thiamine(TTP) at 6mg and back to hav,ing anxiety, weird heart beats and dizziness. I take extra potassium now and I don't plan on trying b1 for a loooong time.
I too had a similar reaction to a simple B1 Thiamine supp (25mg not sure of the exact type of B1) … took it on an empty stomach in the morning and about 45min later .. crazy anxiety attack. Not fun. I can take half the recommended dosage with food and I don’t get that reaction.
@@genxtechguyI’ve just took 100mg of hcl and had the craziest 2hrs anxiety . Was burning hot my skin was prickly felt like I was choking was like a bad trip from my youth 🤣 will try a smaller dose but that wasn’t much fun at all 😢
For what reason do people take thiamin? What is their medical background? I'm suffering from MCAS, histamine intolerance and chronic fatigue after destroying my microbiome 5 years ago and still looking for a cure. Would thiamin help me feel more energy?
Yes it would also methylene blue 🔵
I'll need to listen to this a few more times
You have to have a masters to understand what he’s talking about. LOL
I'm on my 5th time. Brain fog doesn't help either
Insomnia, headache, tachycardia, anxiety, palpitations??!?! Yeah ok no. I think I’ll not dose myself with insane amounts of anything thanks. I don’t understand why people think that just because it’s really bad to be too low in a certain nutrient, that it’s always better to take a high dose so you can have too much of that same nutrient. Talk about oversimplification.
Very generous with your expertise. Thank you.
I got a question. Would taking b1 or the fat soluble vitamins increase other vitamin levels like b2 b6 b12 etc thx
The form of thiamine is important. Thiamin mononitrate causes nonalcoholic fatty liver. There are a number of synthetic forms.
Been on 500mg Benfotiamine for 1.5 years plus probably 50mg HCL in multis. About a year in I started getting so fatigued in the afternoon and evening plus trouble waking at night. I think I replenished any B1 deficiency and caused a magnesium and potassium deficiency. I eat mostly low carb. Starrted upping potassium foods and coconut water plus REMAG solution.
Very detailed and lots of data but not informative. It would be good if You could state therapy/protocol instead of listing 30 supplements that could help.
thank you for using your intelligence for greater good, this information is gold.