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Can anybody explain, how floxed mice used to be generated before CRISPR? People usually say that Cre mouse and floxed mouse can be generated by CRISPR/Cas but Cre-loxP system is older than CRISPR.

What a horrible presentation. Speak slower and pronounce words properly.

amazing video !!! simple and excellent explanation !

Mmmmmm😊

Best video of Cre on RUclips‼️

What an excellent explanation! Very helpful. Thank you.

that was very helpful, thank you!

It looks like in a translocation event the genetic element in question leaves one strand and moves to the other. Isn't there a version wherein the genetic element copies itself onto the other strand while remaining intact on the original strand?

Good info. However sometimes you’re speaking so fast that you’re not fully pronouncing words….

well done! so clearly explained, thank you!

thanks!

excellent video!

thanks, helped a lot

Thanks, I really enjoyed the video and it is very helpful and straightforward.

Ive been researching this for three months and now this suddenly shows up!

Hello. Are PRC1 and PRC2 non-histone proteins?

XD

thanks alot !

Having to learn this for my uni module 😆 crazy how you stumble across these videos so many years later

Hi! The C-terminal domain does not conatin SH3 as you showed in your presentation, the SH3 refers to a specific type of protein-domain common in HIV. The C-terminal domain just folds similar to the SH3-Domain! Thanks for the nice video :)

A very useful presentation, thank you very much. I think it would be very usefull if you have the chance to add subtitles, especially for those whose English is not very well.

Very well explained Shania, thanks for sharing

you go broski

I tip my hat to you sir.

Congrats on this amazing video! Very creative and helpful! Thank you so much for making and sharing it!

This word has left me in physical, emotional, and spiritual pain.

Bad pronunciation

Thanks

My eyes are hurt

Where are the fire flys? Haven't seen them in many years.

That’s a killer intro 🤣

You broke down the steps in such a nice way. Thank you!

What happens if you eat food containing cancer cells or tumor?

Thanksalot you explained it so easily.

Great video!! So educational- I learned so much as a fresh graduate of biochemistry!

Shoutout to Genes, Drugs and Stem cells - novel therapies at Imperial college london you CRISPRy legends

Bro, you just saved a juniors life

Excellent

Hindi m btaye plz

A true legend

Some of the music for the meme sections is too loud, especially in comparison with the volume used in the main education portions. I do like the concept of zooming into a portion of a drawing or diagram and cutting to the education portion. It's a neat idea. I currently am unable to understand what the chemicals and processes are due to my level of knowledge, but I think I can assume that you did a good job at explaining.

Liked and subscribed

This is great, thank you! The end is so funny

Really awesome work

Is this really undetectable?

HI

Your content is so good.. the effort you have taken is marv.. it helped a lot to understand!! Just please have a coffee and record from a place where you can talk loudly "to us" instead of to yourself. Really hard to listen to your breaking hoarse whispery voice even with a high quality headset. I'm sure your real voice is super nice! Please do more videos like this. Subscribing..

the music is too loud. But otherwise, great clip

Wow. This is the best. And so sad... I wanted a happy ending for FEN... But at least I may get a happier ending on my exam tomorrow.

Amazing and well done presentation without the use of powerpoint and animations.