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$150 here in Tennessee

Excelent!

Thanks!

So no info for people with hypertension?

Nothing happened to me when I over did it.

Listened partly with disappointment as true candidate to explain cardiovascular disease and low carb effect is for example dr. Ford Brewer - this would modify this discussion w Nicola Guess greatly (insert exclamation point). Generalist and YouTubist popular such as Attia is incorrect example - not an expert in the matter. Glucose spike and glucose plateau indeed are proxies for insulin baseline (read GCM).

It is so easy to believe some of those influencers, like Peter Attia mentioned by Nicola, once they use some sort of "study" to back up whatever point they make. Most of us don't know whether or not those studies are faulty, or exist at all. It is great to hear what really might be happening in the body from actual experts carrying out research and writing articles. Thanks Glenn!

I was listening on the podcast and was so wishing Dr Sylow had talked about which actual cancers were most positively affected by exercise when she was introducing her work. When she didn't, I wish you had asked her.... I was so curious and interested. Later on a few cancers got mentioned, but only in passing. Worldwide top 5 in order of number diagnosed (2022): lung (12.4%), female breast (11.6), colorectal (9.6) prostrate (7.3) and stomach (4.9)

Europeans did not have their origin in Africa but in Northern Siberia from where most Europeans arrived in wave after wave of migrations by herders rather than hunter gatherers much like the current people of Mongolia. That is why we have white skins and blue/green eyes due to the lack of exposure to sunlight and why we are mainly carnivores who do not have carnivore teeth since we learned to cut up and cook our prey. Slow twitch muscles matched the herder lifestyle and the animals provided the fat. Africans who chased down animals have different bone structure in the calf to foot ratio which is why Ethiopians and Kenyans win the Gold medals at the Olympics in the marathon. It is likely that some African tribes like the Masai have a different muscle fibre ratio to Europeans judging by how high they can jump and for how long.

This is so helpful. Thank you both for taking the time. 😊

When all of this nonsense about eating meat and eggs, protein , fat etc several times daily at 365 days a year has passed , individuals such as myself will still be keeping to what we know works best for the individual, genetics, body type, etc and my ability to function ar such a high level now at age 60 is outstanding, for me a high carbohydrate Whole foods plant based approach is perfect, sustained energy, and cat like agility has changed very little in several decades....

So, what are these minimalists runners doing on race day? Let's sayfor a 5k. Are they racing in the minimalist shoes or do they switch to the carbon plate (assuming they also practiced in them now and then).

Thank you, very good discussion. @1h6min on Metastasis if I understood correctly there is a mechanical mechanism where higher flow through the vascular system prevents cancer cells from establishing themselves in the tissue as well as damaging the cancer cells. Also, there is a boost in immune health which can deal with cancer cells in their early stage. I recall a study presented by Prof Jant Lord who showed that long term older cyclists has preserved thymus function and therefore much better immune system on the order of 2 or 3 decades younger for those in their 70s.

@24:22 he made a claim that 60% plus barefoot runners landed rear foot. Had to check on that. What I found is a couple of experiments that took “mature” or “experienced” athletes and attempts to see what happens when you take their shoes off. These are not barefoot runners. They were single day soft treadmill tests or tests with little to no familiarization and not enough time to adopt the title of barefoot or minimalist runner. Personally I don’t know how import this is anyway, as most trainers now focus on tibial shank angle with 90 degrees being preferable (he does talk about this @39:00). @58:40, Bryan does make a good point that retraining to forefoot takes months to strengthen ankle tendons, tissues, but I believe it’s a small price to pay for the amount of injuries one can accumulate over years and decades of runs. Love these podcasts by the way…very stimulating.

Another gem ❤ Thanks for your work and time

Mr .drave did such a amazing job ...so greatful to heard this podcast ...hats off sir

There is more Melatonin produced and used in peripheral cells during the day than the brain at night. Unlike the melatonin produced in the brain that is linked to the light-dark cycle and influences the circadian master clock , in peripheral tissue It is produced in response to sunlight, especially near infra red and has a neuro-protective, antioxidant and endocrine/paracrine signaling role in cell function especially that of the mitochondria. The brain clock specifically responds to the red light at dawn and sunset and is disrupted by blue light at those times. There is a whole research literature concerning reversal of circadian rhythms in persons working night shifts, submariners and pilots on night flights.

The relaxed style of the chat partnered with the information supported my ability to absorb the information. I’m new to this channel, I am keen to hear more.

Gait and injury. Intriguing. Enjoy 🏋‍♂️🏊🦊🧨

Sttttooop interrupting the speaker!

Enough with the 'OK' interruptions..

Great video! People like the Glucose Goddess should be addressed.

Just found this. Thanks for interviewing Dave! It was great to hear his stories again. I remember him popping in to the clinical ex phys lab when I was a grad student. "Glass, I want to do a stress test" he'd say, and I'd hook him up to an ECG and he'd run his own protocol.

"Experts" are the problem. They're hyperfocused on cholesterol, which shows their bias

Cholesterol isn't a problem if you're metabolically healthy. Stations are garbage

Why does he say cholesterol deposit? It’s more than cholesterol sir!

we love you. Tell us how your calf is holding up.

Dr Glenn. I know you know. I spent some time learning about science: every event alters our likelihood of response. I admire you. You interview people who disagree with you. More than anything, I want to know how your calf holds up when running. I felt such a joy of freedom when I heard you say you would throw your bike into the street. Please tell us how that is going on with you. We love you and need your precious guidance.

Thanks!

Thank you.

It was nice to hear his commonsence opinion of statin drugs and diabetic drugs. He also makes alot of sense talking about exercise. Do what you enjoy and remind ourselves we are not training for the Olympics 😂

How I can support the channel?

Great information!!

Excellent

Nice podcast, do you think you would be able to have Aaron Baggish on the podcast? He's the founder of the cardiovascular performance program in boston Massachusetts General Hospital

@ 1:00:00 . . . The only thing that keeps me from exercising well over 3-6 hrs a day is that my feet hurt. I often hike 8 hours. I just finished a hike that was 10 hours a day for 3 days at high elevation and I'm ready to go out and do it again with a new pair of shoes. I'm 70 years old but have only been doing this for 5 years and never felt better other than the Morton's Neuroma in my left foot that sometimes hurts. I try to keep my HR at or below 145 but I do get it up to 160-170 for short spurts up a steep hill but that's a very low percent of my exercise (1-2%). I try to stick to an 80/20 HR plan but in reality it's more like 90/10 with an occasional race against my own time rather than racing against other people. I doubt I could even run a 10K non-stop trail run but that is on my bucket list.

Great interview, thanks Glenn.

I'm just over half way through and enjoying the interview. I slightly react to one thing and that is the claim that prehistoric man didn't run long distances and that we were not made for that. It is called "persistence hunting" and could reach marathon distances. The evidence of this is pretty undeniable. I'm slightly disappointed that someone whose experise is based on prehistoric man doesn't seem to be aware of this. But that said, all she says makes sense and I agree. I run in barefoot shoes. No big deal.

Thanks!

Incredible episode Dr. Glenn! Super interesting. I was wondering if also lifelong resistance exercisers (or even sports with no aerobic component) have some deleterious effects, like increased arterial stiffness, insulin resistance (due to the high percentage of type 2 muscle fibers), etc... Keep up the great content!!

Not necessarily wrong but Andy has a lot of wires crossed here. Not just forgetting the 20 part of "80/20 z2 training" and the focus on volume and not time-crunched vs "100% z2 training" but the "FTP is Dead" thing he gets worked up over was Sufferfest, not Wahoo.

I believe exercise resistance is the cause of truck drivers being so obese

Excellent insights clearly explained...particularly the paradoxical aspects of calcium burden and exercise , and many other topics.

Very useful👍

👍👍

You need to listen to the people you interview!

I think it's a multi-variable calculus problem that will someday be simulated by computers when the adaptation process is better understood.

Tim Noakes would disagree about the need for carbs for exercise. He has done a 180 degree turn from his earlier view.

I remember watching a presentation by Jeff Galloway. People certainly did get injured during the 70s running boom. That’s why he came up with run walk. But it’s not like run walk was anything new because scout pace was around before that. Scout pace was almost certainly copied from somewhere else. There’s nothing new under the sun as the saying goes.

Very informative. Great guest👍🏼💪🏼😊