Thomas Ouldridge
Thomas Ouldridge
  • Видео 39
  • Просмотров 55 528
Prof Boris Shraiman: Physics of Morphogenesis
Prof. Boris Shraiman speaks at the Imperial Physics of Life seminar series:
www.imperial.ac.uk/physics-of-life/physics-of-life-seminar-series/
Physics of Morphogenesis
Morphogenesis is a developmental process through which plants and animals acquire their shape and form. Although Biology has identified many of the key genes and cellular mechanisms of morphogenesis, the question of how Living Matter encodes the geometry of the shapes that it generates remains an open problem. This talk will focus on the interplay of physical forces and genetically encoded regulation that underly morphogenic processes. Specifically, the talk will describe how mechanical self-organization on cellular scale acts...
Просмотров: 247

Видео

Martin Howard: Setting timescales for epigenetic switching
Просмотров 129Год назад
Martin Howard speaks at the Imperial College Physics of Life seminar series www.imperial.ac.uk/physics-of-life/physics-of-life-seminar-series/ Setting timescales for epigenetic switching Quantitative gene regulation at the population level can be achieved by two fundamentally different modes of regulation at individual gene copies. A “digital” mode involves binary ON/OFF expression states, with...
Victor Sourjik: Physics, physiology and evolutionary optimization of bacterial motility
Просмотров 172Год назад
Victor Sourjik speaks at the Imperial College Physics of Life seminar series www.imperial.ac.uk/physics-of-life/physics-of-life-seminar-series/ Physics, physiology and evolutionary optimization of bacterial motility Bacterial motility is among the quantitatively best-understood biological behaviors, at it has long served as a model of how physics can help to understand limits to bacterial abili...
Ben Simons: Spermatogenesis: a paradigm of stem cell regulation
Просмотров 356Год назад
Prof Ben Simons speaks at the Imperial Physics of Life Seminar Series www.imperial.ac.uk/physics-of-life/physics-of-life-seminar-series/ Spermatogenesis: a paradigm of stem cell regulation To replenish cells lost through exhaustion or damage, tissue stem cells must achieve a perfect balance between renewal and differentiation. To study the factors that control such fate asymmetry, emphasis has ...
Andrew Krause: Heterogeneous and Evolving Domains in Reaction Diffusion Pattern Formation
Просмотров 299Год назад
Dr Andrew Krause speaks at the Imperial Physics of Life Seminar Series www.imperial.ac.uk/physics-of-life/physics-of-life-seminar-series/ Relaxing Turing's Idealization: Heterogeneous and Evolving Domains in Reaction-Diffusion Pattern Formation Motivated by a range of problems in embryology and ecology, I will present recent extensions to Turing's classical reaction-diffusion paradigm for patte...
David Lacoste: Emergence of homochirality in large molecular systems
Просмотров 2852 года назад
Prof. David Lacoste speaks at the Imperial Physics of Life Seminar Series www.imperial.ac.uk/physics-of-life/physics-of-life-seminar-series/ The question of the origin of homochirality of living matter, or the dominance of one handedness for all molecules of life across the entire biosphere, is a long-standing puzzle in the research on the Origin of Life. In the fifties, Frank proposed a mechan...
Prof Pankaj Mehta: Towards a Theory of Microbial Ecosystems
Просмотров 8422 года назад
Prof. Pankaj Mehta speaks at the Imperial Physics of Life Seminar Series www.imperial.ac.uk/physics-of-life/physics-of-life-seminar-series/ Towards a Theory of Microbial Ecosystems. A major unresolved question in microbiome research is whether the complex ecological patterns observed in surveys of natural communities can be explained and predicted by fundamental, quantitative principles. Bridgi...
Jack Szostak: Physics and the Origin of Life, from Chirality to Membranes to Information
Просмотров 7 тыс.2 года назад
Prof. Jack Szostak speaks at the Imperial Physics of Life Seminar Series www.imperial.ac.uk/physics-of-life/physics-of-life-seminar-series/ Physics and the Origin of Life, from Chirality to Membranes to Information Diverse physical processes played important roles in the origin of life. I will review the origin of molecular homochirality, the growth of protocell membranes, and potential roles f...
Lee Cronin: The origin of chemical reactions
Просмотров 2,4 тыс.3 года назад
Lee Cronin's talk at talk at the workshop on nucleic acids, synthetic biology and artificial life: www.imperial.ac.uk/principles-of-biomolecular-systems/workshop-on-nucleic-acids-synthetic-biology-and-artificial-life/ What constrains how a chemical reaction emerges, and what reactions were required for the emergence of life? This is important since discussions about the emergence of life often ...
Dieter Braun: Tracking the first evolutionary steps in non-equilibrium settings
Просмотров 2363 года назад
Dieter Braun's talk at the workshop on nucleic acids, synthetic biology and artificial life: www.imperial.ac.uk/principles-of-biomolecular-systems/workshop-on-nucleic-acids-synthetic-biology-and-artificial-life/ We have driven the first steps of molecular evolution with non-equilibrium settings, often temperature gradients, but also with a recent focus on air-water interfaces. These settings ac...
Domitilla Del Vecchio: Mitigation of context-dependence in mammalian synthetic biology
Просмотров 1363 года назад
Domitilla Del Vecchio's talk at the workshop on nucleic acids, synthetic biology and artificial life www.imperial.ac.uk/principles-of-biomolecular-systems/workshop-on-nucleic-acids-synthetic-biology-and-artificial-life/ Engineering biology has tremendous potential to impact a number of applications, from energy, to environment, to health. As the sophistication of engineered biological networks ...
Damien Woods: 21 molecular algorithms using reprogrammable DNA self-assembly
Просмотров 4693 года назад
Damien Woods' talk at the workshop on nucleic acids, synthetic biology and artificial life www.imperial.ac.uk/principles-of-biomolecular-systems/workshop-on-nucleic-acids-synthetic-biology-and-artificial-life/ In recent work [1] we designed a reprogrammable set of 355 DNA strands, or DNA tiles, capable of implementing a wide variety of algorithms. These tiles undergo algorithmic self-assembly: ...
Elisa Franco: Dynamic self-assembly of encapsulated DNA nanotubes
Просмотров 4643 года назад
Elisa Franco's talk at the workshop on nucleic acids, synthetic biology and artificial life www.imperial.ac.uk/principles-of-biomolecular-systems/workshop-on-nucleic-acids-synthetic-biology-and-artificial-life/ Biological cells adapt, replicate, and self-repair in ways that are unmatched by man-made devices. These processes are enabled by the interplay of receptors, gene networks, and self-asse...
Georg Seelig: Sequence design for gene expression control and DNA computing with machine learning
Просмотров 2553 года назад
Georg Seelig's talk at the workshop on nucleic acids, synthetic biology and artificial life www.imperial.ac.uk/principles-of-biomolecular-systems/workshop-on-nucleic-acids-synthetic-biology-and-artificial-life/ Machine learning models that accurately predict function from sequence are becoming a powerful tool for molecular design. In this talk, I will first present our work on building models t...
Julius Lucks: Programming cell-free synthetic biology diagnostics with RNA/DNA nanotechnologies
Просмотров 1923 года назад
Julius Lucks' talk at the workshop on nucleic acids, synthetic biology and artificial life: www.imperial.ac.uk/principles-of-biomolecular-systems/workshop-on-nucleic-acids-synthetic-biology-and-artificial-life/ Poor water quality affects over two billion people across the globe. While we can’t often see or taste water contaminants, molecular machinery can. Here I will present our latest researc...
Guy-Bart Stan: Discussion of key questions
Просмотров 1653 года назад
Guy-Bart Stan: Discussion of key questions
John Reif: DNA Nanoscience on the Surface of Cells
Просмотров 1273 года назад
John Reif: DNA Nanoscience on the Surface of Cells
Yannick Rondelez: Molecular networks as tools to optimize enzymes
Просмотров 3163 года назад
Yannick Rondelez: Molecular networks as tools to optimize enzymes
Erik Winfree: Thinking about molecular self-assembly that thinks
Просмотров 2,3 тыс.3 года назад
Erik Winfree: Thinking about molecular self-assembly that thinks
Richard Murray: 9 years, 2 months, 16 Days to Go: Progress on Implementing Synthetic Cells
Просмотров 2103 года назад
Richard Murray: 9 years, 2 months, 16 Days to Go: Progress on Implementing Synthetic Cells
Physics of Emergent Behaviour III: from origin of life to multicellularity, 2nd July 2021 (part 1)
Просмотров 2,4 тыс.3 года назад
Physics of Emergent Behaviour III: from origin of life to multicellularity, 2nd July 2021 (part 1)
Workshop on nucleic acids, synthetic biology and artificial life - intro by Thomas Ouldridge
Просмотров 1513 года назад
Workshop on nucleic acids, synthetic biology and artificial life - intro by Thomas Ouldridge
Physics of Emergent Behaviour III: from origin of life to multicellularity, 2nd July 2021 (part 2)
Просмотров 9693 года назад
Physics of Emergent Behaviour III: from origin of life to multicellularity, 2nd July 2021 (part 2)
Prof Jose Onuchic: Energy landscapes, order and disorder, and protein sequence coevolution
Просмотров 3313 года назад
Prof Jose Onuchic: Energy landscapes, order and disorder, and protein sequence coevolution
Lisa Manning: How do single cells program collective behavior at the scale of tissues?
Просмотров 2543 года назад
Lisa Manning: How do single cells program collective behavior at the scale of tissues?
Michael Levin: Anatomical decision-making by cellular collectives
Просмотров 31 тыс.3 года назад
Michael Levin: Anatomical decision-making by cellular collectives
Prof. Ned Wingreen: Magic numbers in protein phase transitions
Просмотров 1 тыс.3 года назад
Prof. Ned Wingreen: Magic numbers in protein phase transitions
Amy Gladfelter: RNA-driven phase separation from cells to SARS
Просмотров 5333 года назад
Amy Gladfelter: RNA-driven phase separation from cells to SARS
Prof. Greg Stephens: Theory, reimagined
Просмотров 2753 года назад
Prof. Greg Stephens: Theory, reimagined
Arvind Murugan: Neural network like collective dynamics in molecules
Просмотров 6433 года назад
Arvind Murugan: Neural network like collective dynamics in molecules