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Bay Bridge Bio
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Добавлен 2 окт 2018
Bay Bridge Bio supports the next generation of biotech entrepreneurs and investors. We help you understand the industry, stay on top of trends, and make better decisions.
Our content covers biotech venture capital, startups, finance, investing and emerging technologies. Whether you are an investor, CEO of a startup, or a scientist looking to learn more about entrepreneurship, we want to help you solve problems with better information.
For more content, check out our website and blog: www.baybridgebio.com/
Our content covers biotech venture capital, startups, finance, investing and emerging technologies. Whether you are an investor, CEO of a startup, or a scientist looking to learn more about entrepreneurship, we want to help you solve problems with better information.
For more content, check out our website and blog: www.baybridgebio.com/
The biotech venture capital crunch
Biotech venture capital investment is slowing down, and startups may have a hard time raising. We explain the money behind why venture investors are changing how they invest, and what it means for founders.
This video is sponsored by Sage Intacct. Learn more here: sageintacct.com/biotech
This video is sponsored by Sage Intacct. Learn more here: sageintacct.com/biotech
Просмотров: 4 837
Видео
Bargain hunting for biotech stocks
Просмотров 10 тыс.2 года назад
My process for finding biotech stocks with strong fundamentals and reasonable value. I discuss the rationale for one stock screen and briefly review four stocks: ACHL, SCYX, CYT and GRPH. This is not investment advice. As of the posting of this video, I don't hold positions in any of these companies, but I may in the future. This content is meant to be educational.
Why short selling biotech stocks is dangerous
Просмотров 4,3 тыс.2 года назад
What short selling is, why it is dangerous, good reasons to short, and what makes a good short pitch.
How dilution can crush biotech returns
Просмотров 2,2 тыс.2 года назад
We discuss how dilution can wipe out returns, and how to avoid dilution.
Quantifying clinical trial probability of success estimates
Просмотров 2,5 тыс.2 года назад
Frank David joins us to walk through resources for quantifying probability of success estimates. Check out Frank's books on analyzing clinical trials and biotech forecasting and valuation here: www.pharmagellan.com/books And check out Frank's blog post on his framework for clinical trial risk here: www.pharmagellan.com/blog/clinical-pos
Case study in analyzing biotech clinical trial risk
Просмотров 2,8 тыс.2 года назад
Frank David joins us to walk through an example of analyzing clinical trial risk. Check out Frank's books on analyzing clinical trials and biotech forecasting and valuation here: www.pharmagellan.com/books And check out Frank's blog post on his framework for clinical trial risk here: www.pharmagellan.com/blog/clinical-pos
Analyzing biotech clinical trial risk: Frank David, founder of Pharmagellan
Просмотров 5 тыс.2 года назад
Frank David joins us to walk through a framework for estimating clinical trial probability of success. Check out Frank's books on analyzing clinical trials and biotech forecasting and valuation here: www.pharmagellan.com/books And check out Frank's blog post on his framework for clinical triak risk here: www.pharmagellan.com/blog/clinical-pos
Analyzing FDA's statistical review of a Phase 3 program
Просмотров 1,2 тыс.2 года назад
We analyze FDA's statistical review of aducanumab using points brought up by the Ad Comm panel. More info on the adcomm here: www.fda.gov/advisory-committees/advisory-committee-calendar/november-6-2020-meeting-peripheral-and-central-nervous-system-drugs-advisory-committee-meeting
Analyzing FDA Ad Comm minutes: was the aducanumab Ad Comm biased?
Просмотров 1,2 тыс.2 года назад
We analyze FDA's briefing package and review for the Ad Comm meeting. Meeting transcript here: www.fda.gov/media/145691/download Meeting recording here: www.fda.gov/media/143513/download Meeting materials here: www.fda.gov/advisory-committees/advisory-committee-calendar/november-6-2020-meeting-peripheral-and-central-nervous-system-drugs-advisory-committee-meeting
Intro to FDA Advisory Committee meetings: aducanumab's AdComm
Просмотров 1,6 тыс.3 года назад
We discuss the controversial FDA AdComm meeting for Biogen's aducanumab, a drug being developed to treat Alzheimer's disease. Link to the FDA's website with AdComm materials: www.fda.gov/advisory-committees/advisory-committee-calendar/november-6-2020-meeting-peripheral-and-central-nervous-system-drugs-advisory-committee-meeting
Critically analyzing clinical data: post-hoc analysis of aducanumab
Просмотров 2,5 тыс.3 года назад
Follow along with Biogen's slides here: investors.biogen.com/static-files/5a31a1e3-4fbb-4165-921a-f0ccb1d64b65
Analyzing the clinical data for Aduhelm, Biogen's controversial Alzheimer's drug
Просмотров 3 тыс.3 года назад
We analyze Aduhelm's clinical data for Alzheimer's to illustrate basic concepts in biotech investing. This is the first of a series of videos on Aduhelm, covering clinical data and how clinical data impacts regulatory and commercial considerations.
Intro to clinical data: biotech investing basics
Просмотров 4,9 тыс.3 года назад
This video discusses the basics of interpreting clinical data to help you make biotech investment decisions. We use the example of NXTC, a cancer company, to highlight some of the pitfalls of interpreting clinical data as well as basic concepts in oncology clinical development.
Biotech investing basics part 4: DCF analysis
Просмотров 16 тыс.3 года назад
GOOGLE SHEET HERE: docs.google.com/spreadsheets/d/1kngDNmjlS615JBNWyeMmnsdaeERSuS8QQCEbPqBiVaA/edit?usp=sharing The google sheet includes a sample DCF with comments explaining each line item and how to forecast them. If you have questions let me know in the comments.
Biotech investing basics part 3: intro to valuation
Просмотров 8 тыс.3 года назад
This video discusses why valuation matters in early-stage biotech investing and provides an overview of basic valuation techniques.
Leaving your job to start a biotech company: interview with Geoff Harris, CEO of Ocelot Bio
Просмотров 2 тыс.3 года назад
Leaving your job to start a biotech company: interview with Geoff Harris, CEO of Ocelot Bio
Biotech investing basics part 2: measuring value in biotech
Просмотров 13 тыс.3 года назад
Biotech investing basics part 2: measuring value in biotech
Biotech investing basics part 1: value in biotech
Просмотров 29 тыс.3 года назад
Biotech investing basics part 1: value in biotech
Starting a company as a scientist: interview with Matt Krisiloff
Просмотров 1,4 тыс.3 года назад
Starting a company as a scientist: interview with Matt Krisiloff
How startups can fight "Eroom's Law": interview with Jack Scannell
Просмотров 1,9 тыс.4 года назад
How startups can fight "Eroom's Law": interview with Jack Scannell
Building longevity startups with Laura Deming, founder of Longevity Fund
Просмотров 1,7 тыс.4 года назад
Building longevity startups with Laura Deming, founder of Longevity Fund
Funding for moonshots: funding biotech and hardtech companies with Max Altman, co-founder of Apollo
Просмотров 1,5 тыс.4 года назад
Funding for moonshots: funding biotech and hardtech companies with Max Altman, co-founder of Apollo
How to license technologies from universities as a biotech startup
Просмотров 2,3 тыс.4 года назад
How to license technologies from universities as a biotech startup
Finding a "killer application" for novel biotech: AveXis case study
Просмотров 1,1 тыс.4 года назад
Finding a "killer application" for novel biotech: AveXis case study
Coming up with ideas for biotech startups
Просмотров 9 тыс.4 года назад
Coming up with ideas for biotech startups
A process for finding and validating biotech startup ideas
Просмотров 1,7 тыс.4 года назад
A process for finding and validating biotech startup ideas
How to pitch to biotech venture capitalists: two "mock pitches" plus fundraising tips
Просмотров 16 тыс.4 года назад
How to pitch to biotech venture capitalists: two "mock pitches" plus fundraising tips
How to start a biotech startup: 5 young VC-backed founders share their stories
Просмотров 30 тыс.4 года назад
How to start a biotech startup: 5 young VC-backed founders share their stories
Hello, thanks for the lesson, How can I edit and change data in the Google file, Looks like you need permission to edit thanks
Hey man, I really appreciate this video, really the most practical describing a proper DCF specific for biotech industry. I am doing my finance msc and my thesis is about valuing a biotech. I will build my model based on this video, not entirely but heavily inspired. I cannot cite you tho since it's a youtube video. By chance, do you have any relevant literature that describes this process the way you just did? Or anything academic that you or someone else wrote regarding this specific area?
this video series is extremely helpful. pharmd soon to be md, but have always been involved in biotech speculating, I call it that instead of investing because i have no finance background. have been building models for phase 3 drugs for prerevanue single drug companies and have been pretty lucky so far. started with a company called AVEO, and made out alright after they were bought by LG chem i think last year. they had a drug which went though the entire phase 3 and failed at the finish line, and then changed their indication to be specific for pdl-1 RCC, which did well in their subgorup analysis of their tivo-2 trials. I was able to made a somewhat robust model and use montey carlo to fill in the gaps before a lot of the trial info was released which proved valid. now i got this company that i hate, RIGL which is like a 3 drug post revanue company and im trying to figure out when to dump the stock coz i think a buyout is comming now that theyre somewhat profitable. really like their drug on the market, we had a few patients on it in a clinic I was at. I really wonder how finance bros even begin to wrap their head around place in therapy and indications lol. hoping thats an edge. really interesting drug if youre into pharmacology: Fostamatinib, sold under the name Tavalisse, which is kind of its own catagory of drug right now, approved only for ITP but some really interesting applications. feel like most of the money pharma makes is at heme onc clinics since its so many one off diseases and life determining treatments. thanks for uploading all this, there was nothing like this on youtube 5 years ago when i looked, thanks richard
26:00 how the hell do you build a company when they want to track you for 5 years before they commit check
Already be rich.
Tbh it seems that you need data before you can get money to get more data. You're gonna need to get some data some way some how - and if the data is good you'll get people investing. But data comes first. Not sure how you're supposed to get that initial data. I suppose that's why the vast majority of biotech startups are from scientists in academia that use the findings they've already developed in their labs. They already have the initial data they need
@sulemanqamar3068 Angel investors who can endorse and advocate for your history as expert, and are willing to contribute a small pre-seed package for you.
Great examples, very helpful
Would love to see a close out video on recent news about Aducanumab and also any thoughts you have on Lecanemab's approval and prosects.
Awesome video! Cheers from Brazil.
Would you be so kind to valuate Cassava Sciences. Small Biotech in the Alzheimer's Space. Thx.
💯💯💯
Thank you for making.
Nobody is holding a short position for years...misleading video. You absolutely can short biotechnology successfully because most of these companies are unprofitable and in debt, but it must be a quick trade.
Cereno Scientific NeXT ❤
Yes, content level is beyond imagination!
Such a great videos! Thank you so much for sharing your knowledge! Hope you will not abandon this channel
This is a supremely helpful video. Thank you! We hope you come back ❤
Why is this old information still on here?!
Thank you so much for these amazing series! Happily subscribed.
These videos are amazingly informative, thank you so deeply for your efforts and generosity
What the heck man. This stuff is great, I really don’t get the lack of attention to this channel.
You need to keep this channel going, I’m not new to trading but the things you teach are excellent I learn a lot from you! It’s sad that people don’t want to learn they just want easy money and ad revenue dictates that by giving a great channel less views… But you are a great resource and I hope you keep the content going.
Great stuff would like to see the next part
High quality content
Why’d you stop making videos
Underwhelming talk. Very generic and useless honestly
What tool did you use for the model?
Very helpful video, thank you! Do you know of any good resources to help develop assumptions to project any post-approval R&D costs?
in hindsight the downturn was caused by a lot of small early clinical to preclinical start up going public, receiving mountains of cash from braindead investors then those investors crying after not following the golden rule of biotech/pharma "90% of drugs fail to get through the clinic" So it doesn't seem like to me biotech had the problem , the problem are venture capital bros who don't understand what they are investing in because they played they were lucky on the stock market or born into money, or they went to an ivy league school and people gave them money under assumption they were intelligent. The problem was too many stupid people had too much money, and we will see the same exact behavior with AI start ups and it will be even more volatile because they don't have to go through anything like the FDA to get to market. part of our problem is a problem of culture and assuming a lot of money means a person is intelligent or we will keep repeating the same mistakes with every tech sector until we get some better investors, because most won't say it , but most of them want to be the next Martin Shkreli minus the prison.
This case study was fascinating, thanks!
Many thanks Man!!
this video prevent degen from turning into serial killer.
As someone who is an early employee of a startup, this video was significantly helpful. Thank you.
Question : is there a general rule on whether to start with incidence or with prevalence?
Do you have any thoughts about Takeda's Qdenga vaccine?
Thank you for this truly great deep dive into some promising advances. Hoping to hear more about what you think going forward.
Great content, thank you Richard!
1 year later GRPH remains at $2.56
Hey, awesome video! I was trying out a valuation for a small biotech and realized that I was having some trouble finding the list price for drugs and information on drug penetration for benchmarking. Is there a database where we can find these values or are they provided in one of the financial statement documents? I apologize if this is a really basic question - my background is in science so I am a bit unfamiliar with the more financial/ cost projection side of things. Thanks in advance!
Legend. Best channel.
look for INVITAE ❤❤❤❤❤❤❤its my absolute favourite healthcare company
Legend. Best channel ever.
Awesome man, thank you so much for this
great series. I was alarmed, when you mentioned Seres. At first I thought, you are going to talk about Syros (where I am invested in). But I am not english native speaker so I just got it wrong. However I would appreciate your 2 cents regarding Syros Pharmaceuticals (Flagship Pioneering is Co-Founder here).
Great content. Would love to see you cover Argenx
Thank you for this. Question... I often use operating cash flow for a non-revenue generating companies like biotech. Would that be a reasonable surrogate? I imagine using the income statement might factor in other non-recurring factors? Thanks!
Extremely well-structured content. Also, really really legit approach to the analysis. Thanks a lot! Got lucky finding this
Great overview. Thank you
Great introduction. Looking forward to the additional videos
Your content is awesome plainly simple
Great summary. Need more videos! 🎉
Great details 👍
Awesome content Richard! Keep the analysis videos coming :-)