Gavin Giovannoni
Gavin Giovannoni
  • Видео 65
  • Просмотров 203 862
Multiple sclerosis - “A road less travelled with miles to go before I sleep
My talk on MS prevention delivered at the Mansell Competition held at the Medical Society of London, Monday 10th June 2024.
Просмотров: 1 036

Видео

The case for offering AHSCT as a first-line treatment for MS
Просмотров 2,8 тыс.Год назад
A talk I gave at the 3rd International Symposium on Stem Cell Treatment in Multiple Sclerosis , Friday 20th January 2023, Sheffield.
The Future of Multiple Sclerosis Therapy
Просмотров 12 тыс.Год назад
This is a talk I gave last week in Germany on the Future of MS care. Most of the content I have presented before. I hope you enjoy it.
Flipping the pyramid and beyond ECTRIMS 2022
Просмотров 1,3 тыс.Год назад
This is a test run of my ECTRIMS 2022 hot topics presentation on the arguments for flipping the pyramid.
The holistic management of MS - treating MS beyond DMTs
Просмотров 3,8 тыс.2 года назад
The re-recorded talk I gave at the South East of England Neurology Association (SENA) meeting on the 22-April-2022.
COVID-19 and the Impact on MS Rehabilitation in the COVID-19 ERA
Просмотров 3662 года назад
My keynote lecture at the RIMS 2021 online conference. In this lecture, I explain the impact COVID-19 has had on people with MS and use my own lived experience from my accident and polytrauma to illustrate the importance of prehabilitation and rehabilitation.
Benign fasciculations of the calf
Просмотров 75 тыс.2 года назад
Exercise-induced (running) benign fasciculations of the calf.
Treating beyond NEDA to tackle the unmet need of smouldering MS
Просмотров 9173 года назад
A short commentary of going beyond NEIDA (no evident inflammatory disease activity) to target smouldering MS and to prevent ongoing end-organ/brain damage in MS.
Improving communication, engagement and adherence in MS patients. Are digital technologies the key?
Просмотров 2663 года назад
Teaser web.cvent.com/event/3cac1f37-053d-4f79-83c3-ae1cddf2028f/summary
Why is the SIZOMUS study so important for people with MS?
Просмотров 2,7 тыс.3 года назад
A short description of what we are trying to do with the SIZOMUS trial.
Under&Over
Просмотров 2093 года назад
A short explanation of why we the under&over study is so important.
Ben Jacobs Barts MS Journal Club 23 Feb 2021
Просмотров 1793 года назад
Nakatsuka et al. Two genetic variants explain the association of European ancestry with multiple sclerosis risk in African-Americans. Sci Rep. 2020 Oct 9;10(1):16902. doi: 10.1038/s41598-020-74035-7. Epidemiological studies have suggested differences in the rate of multiple sclerosis (MS) in individuals of European ancestry compared to African ancestry, motivating genetic scans to identify vari...
Copy of Barts-MS Vaccine Hesitancy Livestream
Просмотров 1163 года назад
Copy of Barts-MS Vaccine Hesitancy Livestream
Barts MS Journal Club 16-Feb-2021
Просмотров 1203 года назад
Barts MS Journal Club 16-Feb-2021
Barts MS Journal Club 9- Feb-2021
Просмотров 1353 года назад
Barts MS Journal Club 9- Feb-2021
Orientation to Barts-MS in Whitechapel
Просмотров 1473 года назад
Orientation to Barts-MS in Whitechapel
Barts MS Journal Club 26 Jan 2021 Ide Smets Ofatumumab vs Teriflunomide
Просмотров 6073 года назад
Barts MS Journal Club 26 Jan 2021 Ide Smets Ofatumumab vs Teriflunomide
Barts-MS Journal Club Dr Ide Smets Fatigue Treatments 21-01-21
Просмотров 1433 года назад
Barts-MS Journal Club Dr Ide Smets Fatigue Treatments 21-01-21
Barts-MS Journal Club 28 Oct 2020
Просмотров 3573 года назад
Barts-MS Journal Club 28 Oct 2020
Barts-MS Coronavirus Antibody Study
Просмотров 2643 года назад
Barts-MS Coronavirus Antibody Study
Barts-MS Journal Club 28 Sept 2020 - Journal Club
Просмотров 1083 года назад
Barts-MS Journal Club 28 Sept 2020 - Journal Club
Making the case for flipping the pyramid to treat MS
Просмотров 1,1 тыс.4 года назад
Making the case for flipping the pyramid to treat MS
Barts-MS Journal Club Saul Reyes 9th-Sept-2020
Просмотров 1854 года назад
Barts-MS Journal Club Saul Reyes 9th-Sept-2020
Prof G on vaccines and DMTs
Просмотров 4364 года назад
Prof G on vaccines and DMTs
Barts-MS Journal Club Dr Aboulwafa
Просмотров 2694 года назад
Barts-MS Journal Club Dr Aboulwafa
Barts-MS Journal Club Ide Smets on RIS - 2
Просмотров 2694 года назад
Barts-MS Journal Club Ide Smets on RIS - 2
The Kingdom of the Sick an interview with Rachel Horne - July 2020
Просмотров 3464 года назад
The Kingdom of the Sick an interview with Rachel Horne - July 2020
Introduction to the virtual neurological examination or virtuEx
Просмотров 3044 года назад
Introduction to the virtual neurological examination or virtuEx
Smouldering MS - The Real MS
Просмотров 4,8 тыс.4 года назад
Smouldering MS - The Real MS
Preserving Brain Health in time of COVID-19
Просмотров 2344 года назад
Preserving Brain Health in time of COVID-19

Комментарии

  • @brentpope100
    @brentpope100 10 дней назад

    do you still get these everyday

  • @isma6168
    @isma6168 23 дня назад

    Bonjour avez vous toujours ces fasciculation

  • @amyalewine
    @amyalewine Месяц назад

    Myofascial Release will calm this condition. It will need to be done regularly, but things will improve.

  • @grzegorzl4825
    @grzegorzl4825 Месяц назад

    I have the same for about 6 months .... constantly

  • @kamyarkarimi
    @kamyarkarimi 2 месяца назад

    Magnesium will help

  • @bethbroun9753
    @bethbroun9753 2 месяца назад

    How can I get in the trial in the US? I have PPMS

  • @paranormalinthefunhouse
    @paranormalinthefunhouse 2 месяца назад

    Had this for half a month now

  • @lovemytide45
    @lovemytide45 3 месяца назад

    I have ALS and fasciculations were my first visible symptoms. They are often nothing to worry about but they can also be a sign of something devastating

    • @ЯрославРоманюк-ю9т
      @ЯрославРоманюк-ю9т 3 месяца назад

      How long it takes from start of fasciculations to weakness?

    • @lovemytide45
      @lovemytide45 3 месяца назад

      @@ЯрославРоманюк-ю9т good question that is extremely difficult to answer. Probably, and this is a guess… about a year. I was diagnosed on July 14, 2020 but probably had it at least a year or longer before I really noticed weakness. Another early symptom for me was balance. I started washing my hair with one hand on the shower wall because the slight floor drain grade of my shower was throwing my balance off. I didn’t know what it meant until I started looking back and things started to make sense. Fatigue was also big. I could only last 1/2 as long as I once did in my yard but blamed it on getting older and being out of shape.

    • @ЯрославРоманюк-ю9т
      @ЯрославРоманюк-ю9т 3 месяца назад

      @@lovemytide45 thank you for answer,sorry if it i disturbing with those questions.What about location,fasciculation when started was in one zone(arm,leg),or symetrical on both legs/arms?

    • @lovemytide45
      @lovemytide45 3 месяца назад

      @@ЯрославРоманюк-ю9т Ask as many questions as you like. I’m a national ambassador for ALS and I actually enjoy talking about it . Mine started in my calves. Left calf specifically. I can’t remember how long before I noticed my fasciculations moving to different areas of my body. I actually thought it was an electrolyte imbalance so I loaded up on potassium because I had not been diagnosed yet. However, ALS can show up in different areas such as arms or neck. Neck is called bulbar onset and it usually progresses faster than others. I’m going to post my story here 👇. I have it saved in my notes and hopefully it will transfer over. There have been some questions about my symptoms and onset. I am typing this in my notes on my iPad and hopefully it will copy/ paste over. Here is part of my story I want to point out that there is NO test to determine ALS. ALS is diagnosed by ruling everything else out so time is crucial. Only 10% of ALS patients are in a clinical trial. First noticeable symptoms The slight grade on the shower floor was throwing me off balance so I would wash my hair with one hand on the wall. Fatigue. I used to spend 6 hours in my yard and I started to last only 3. My gait was off and I slapped my feet when I walked … hindsight, known as Left Foot Drop My legs always felt full of blood. Like they we going to explode after a long day in the gym. Hindsight- my body was incorporating muscles not intended for the heavy lifting of walking which resulted in them being over exerted and full of blood. My wife is a Nurse Practitioner and connected all the dots. She got me in to see a neurologist ASAP. They did an EMG which is a test where they stick passive listening devices into your muscles at various points and listen to the sound of your muscles communicating. EMG has been around a long time. Yes, it hurts like hell…especially when they rammed the probe through the soft tissue under my chin in order to listen to my tongue. They also do a nerve conduction test where they shoot low voltage pulses into your muscles to test the communication between your nerves and muscles… yes, it hurts like hell too. After I was diagnosed locally, me, my wife and my sister drove from Alabama to the Mayo Clinic in Rochester, MN for a confirmation diagnosis. Great facility. Once confirmed we shifted into Clinical Trial mode. I got into a trial at Mass General Hospital in Boston. In my opinion, Mass General has the best neurologist in the world. My wife and I flew from Alabama and stayed in Boston for 5 days a month for 2 years. I received over 35 spinal taps with an experimental drug that has recently been FDA approved. UNFORTUNATELY, I developed severe side effects that were killing me faster than my disease so I had to pull out… after 2 years. It sucked but that’s what clinical trials are for. I am currently on a regimen of newer versions of older drugs until I can get into another trial which is a long shot because my lung function is declining due to my ALS. You must have a certain lung function to qualify for many trials. I am ALWAYS searching for new clinical trials that I can apply for.

    • @gavriele7953
      @gavriele7953 2 месяца назад

      Where it is started? All over the body or a leg... arm...?

  • @Change_O
    @Change_O 3 месяца назад

    Ive just read that EBV causing mono is usually contagious for six months but can be as long as 18 months. That's a lot longer than I expected.

  • @naglastuden39
    @naglastuden39 3 месяца назад

    A comorbidity? Thanks for stalling our treatment for decades. You big pharma paid stool pigeon.

  • @lynneheal-xc2qg
    @lynneheal-xc2qg 3 месяца назад

    A #publicinquiry is needed into all #MS deaths and what medications they all took.

  • @marcosmoreno1299
    @marcosmoreno1299 3 месяца назад

    I have it all over my body my legs back arm even my tongue sometimes I can feel them in my ear even on my head.. it's bfs .. As long as you don't experience lost of muscle weekness don't stress over it you will learn to live with them I did been with them for 12 yrs .. Enjoy life don't stress over it the more you read about it the more you get scared .. Remember if u do see muscle decline do go get check with a neurologist .. My neurologist said I had nothing wrong but I researched my self made a conclusion of bfs..

  • @mikejames6408
    @mikejames6408 3 месяца назад

    Thanks Prof G for this presentation and all the best for your research into treating IM.

  • @amandatyler3485
    @amandatyler3485 4 месяца назад

    _I am so happy for my Sister, she got cured of her Multiple Sclerosis just few weeks of using Dr Madida Sam herbal supplements🌿🌿.._

  • @janeca10
    @janeca10 4 месяца назад

    Dr Giovannoni, your commitment to the MS cause is very special and causes a positive impact across the world. Thank you!

  • @youandmeandmultiplescleros402
    @youandmeandmultiplescleros402 4 месяца назад

    Thanks for keeping us up to date, Prof G!

  • @TheCuppaCake
    @TheCuppaCake 4 месяца назад

    Thx as well! A fantastic presentation. I too am a 58 yr old female with RRMS - and I hope it will happen in my lifetime as well!

  • @themilkman7367
    @themilkman7367 4 месяца назад

    Is it possible, that the increase in MS numbers in developed countries could be due to age, specifically later age, of EBV infection? We know IM is generally due to being infected with EBV after the age of 15. Looking at developing countries, like in south east Asia, the children are almost all EBV positive by the age of 10. These developing countries also have almost no MS cases. I surmise if we infect children before the age of 10 with EBV, we will see a subsequent reduction in MS cases.

    • @themilkman7367
      @themilkman7367 4 месяца назад

      Ok, looking at the slide 44:40 shows what I was referring to. The real question is what about the people with "no EBV infection"? Maybe we should be looking at this cohort as well. Maybe asking ourselves: why do these people have the diagnosis of MS without EBV infection? Do these people have MS disease or another 'MS-like disease'?

    • @ProfessorGiovannoni
      @ProfessorGiovannoni 4 месяца назад

      Yes, it is possible and likely. The vertical transmission (mother or grandmother to child) of EBV from food is being replaced by later horizontal transmission of EBV (kissing) in these countries. The cultural practices of mothers and grandmothers softening food for weaning babies by chewing it is gradually being replaced by Western habits of using appliances to do this or purchasing bottled food.

    • @ProfessorGiovannoni
      @ProfessorGiovannoni 4 месяца назад

      @@themilkman7367 Trying to find EBV negative people to study is easier said than done.

    • @themilkman7367
      @themilkman7367 4 месяца назад

      ​@@ProfessorGiovannoni So in theory we should be trying to infect children with EBV before the age of 15 until we have a working vaccine. This should hopefully protect against IM and reduce the risk of developing MS. Another questions I have is what will it take to get your proposed studies off the ground? Has anything been done with iTERI? Plasma Cell removal in the CNS? What do pilot studies cost these days? 1 Million? 10, 100M?

    • @Change_O
      @Change_O 3 месяца назад

      EBV can also be spread through sharing lollipops, sharing unwashed cups and cutlery. Even exposure to coughs and sneezes. This needs to be mentioned.

  • @andrews3347
    @andrews3347 4 месяца назад

    You could have been talking about my early infection with EBV, my strep throat for decades or my 30+ years with MS. I do wish you would revisit valacyclovir. It does cause chain termination, so you get a prophylactic for lytic replication. It works because there isn't a hydroxyl group on the third carbon of acyclovir triphosphate. Those old test valacyclovir tests for MS never looked at EBV, they just wanted patients to show improvements on walking tests. Clearly, that's a nonsense hope. You should also look at the small non-coding EBV RNA called EBER2. It's essentially an analog of adenosine deanimase, and when it out competes that enzyme, you get a rise in adenosine levels. That higher adenosine level will downregulate CD8+ cells and open calcium channels ( P2X4 and P2X7) causing a calcium overload in neurons, oligodendrocytes and astrocytes. I've been taking 2x500mg of valacyclovir daily for 20 years, so I know it works. It can't possibly affect latent EBV infection so the assays will show it's there, but the lytic phase is contained by the antiviral.

  • @alanmcpherson3682
    @alanmcpherson3682 4 месяца назад

    Thanks for posting and your efforts in the MS sphere.

  • @__Wanderer
    @__Wanderer 4 месяца назад

    Shocked antivirals haven't been more broadly tested - I am sure there are hundreds if not thousands willing to test it, including myself. Within a year we would know the answer of combined annual relapse rate using patient data / patient years vs relapse rate...

    • @themilkman7367
      @themilkman7367 4 месяца назад

      There was a study with valacyclovir showing a 30 percent reduction in RR.

  • @__Wanderer
    @__Wanderer 4 месяца назад

    Very interesting topic thank you - as someone with MS I do also hope that an EBV vaccine may help regulate EBV / reduce relapses. My very first relapse came 3-4 weeks after a covid infection. I highly suspect I may have had an EBV reactivation at the same time as being ill with covid. Worst sore throat I have had in my life - could barely swallow soup. 3-4 weeks after I went blind in my left eye and never recovered from that. Since that point MRIs have shown MS as a diagnosis. Prior to being ill I had never had any indication of MS. Is the link between COVID / EBV also known as a trigger for MS?

    • @themilkman7367
      @themilkman7367 4 месяца назад

      There is a link between covid spike protein mimicking myelin, published on the WHO website in 2022. It is also known COVID can often cause EBV reactivation. My first relapse was after my first COVID infection as well.

    • @__Wanderer
      @__Wanderer 4 месяца назад

      @@themilkman7367 Indeed it does seem there are a large amount of neurological issues triggered by COVID. I am a little surprised there is such a lack of interest in this mechanism of reactivation. For me it was FAR too coincidental timing wise for it not to be causal. My neurologist didn't seem to care at all when first discussing this. It is a shame that this kind of data isn't being collected when being a new patient. There is so much data that could be collected to help crack the MS code but is simply not done... Hope you are doing well, are you on medication now?

    • @ProfessorGiovannoni
      @ProfessorGiovannoni 4 месяца назад

      About two-thirds of people with long-COVID have evidence of EBV reactivation. So some of the symptoms of long-COVID may be EBV related. However, there is no link I am aware of between COVID-EBV and MS.

    • @__Wanderer
      @__Wanderer 4 месяца назад

      @@themilkman7367 Indeed I have heard a lot of very strange neurological disorders in individuals post Covid infection - my friend had guillain barre syndrome for several weeks after a Covid infection. Spent months recovering from it. A little surprised there is not more attention for the severe neurological impact the virus has on young individuals. Long covid included!

    • @__Wanderer
      @__Wanderer 4 месяца назад

      @@ProfessorGiovannoni Interesting that there seems to be a link with long covid & EBV. Long covid is also thought to be a nervous system issue (at least in part) from what I have read. I don't have long covid luckily. I do still wonder if a novel infection such as Covid allowed for an opportunistic re-infection of EBV as EBV is latent in ~95%+ of people from what I understand. Similar to a cytokine storm perhaps EBV is able to wreak havoc in a COVID compromised immune system.

  • @Robin-me8fe
    @Robin-me8fe 4 месяца назад

    Thanks.

  • @sanaealloul884
    @sanaealloul884 4 месяца назад

    Me after astrazeneka

  • @EvenSoItIsWell
    @EvenSoItIsWell 4 месяца назад

    Thanks Dr. G. 58yo female here with RRMS. I am hopeful it will happen in my lifetime too!

  • @shanethecolloidalsilverman718
    @shanethecolloidalsilverman718 4 месяца назад

    Also copper and vitamin b12 help regrow myelin as well

  • @shanethecolloidalsilverman718
    @shanethecolloidalsilverman718 4 месяца назад

    One three things can cause ms dietary allergies like gluten and heavy metal toxicity in neural tissues and three lack of vitamin D3 massive deficiency and intravenous colloidal silver can reverse brain lesions, remyelinization of the myelin complete remission of ms so you can say a cure but you’ll have to see a naturopathic or integrative medical doctor for that treatment

  • @jas350
    @jas350 5 месяцев назад

    Mine happens all over my body after I received a nerve block before surgery

  • @briangallagher6624
    @briangallagher6624 5 месяцев назад

    Taking enough magnesium glycinate has just about cured this for me. I also drink Keto Chow Daily Minerals in 2 liters of water along with 1 1/2 teaspoons of pink salt every day. I seem to need extra electrolytes no matter what my diet is.

    • @GBadventure
      @GBadventure 3 месяца назад

      Enough salt is solution???

    • @briangallagher6624
      @briangallagher6624 3 месяца назад

      @@GBadventure possibly. It may be a combination of things. I used magnesium glycinate along with drinking salt for years but things didn't really click until I upped the magnesium dose and introduced Keto Chow Daily Minerals to the daily mix.

    • @texasnative
      @texasnative 2 месяца назад

      I've had constant and I mean constant 24/7 calf twitching for almost 40 years. I'm 52 and I remember having this since I was a teenager. How much magnesium glycinate do you take each day?

    • @2111clem
      @2111clem 17 дней назад

      @@texasnative I'd be interested as well

    • @sabrinam.3576
      @sabrinam.3576 9 дней назад

      ​@@briangallagher6624 hello

  • @2111clem
    @2111clem 5 месяцев назад

    I have had fasciculations in both claves with chronically elevated levels of CPK, creatinine, ferritin… for more than 15 y. Recently, fasciculations extended to other parts of my body (upper legs, back, arms …) and I was diagnosed a neuropathy. Still looking for the exact disease… no loss of weight but a lot of muscle and joint pain. Looking for people with similar symptômes.

    • @spaceoddity54
      @spaceoddity54 3 месяца назад

      How are you doing now? I have constant twitching in my calves.

    • @ReallyJustAnotherDay
      @ReallyJustAnotherDay 28 дней назад

      I'm sorry you're experiencing this. Ive had fasciculations since late 2021, interestingly I have raised ferritin also but low transferrin sat and Serum Iron, no cause has yet been found in my case either

    • @ReallyJustAnotherDay
      @ReallyJustAnotherDay 28 дней назад

      I also get the muscle pain and joint pain

    • @soum.m4313
      @soum.m4313 24 дня назад

      Bonjour où en êtes vous aujourd'hui ? J'ai également des fasciculation depuis 1 an maintenant, des douleurs articulations et musculaire

    • @2111clem
      @2111clem 21 день назад

      ​@@spaceoddity54 I’ve been investigating my health issues extensively and recently got diagnosed with two autoimmune diseases: Hashimoto's (though my hormone levels are still within a good range, so no major concerns) and Gougerot-Sjögren (causing dry eyes and mouth). However, I don't think these conditions are directly related to my main problems. In my opinion, they might be a result of chronic inflammation. I've consulted with internists, muscle specialists, and more. But when they see me in relatively good muscular shape, they seem to dismiss the idea of muscle issues-even though I experience significant fasciculations, which they often deny are present. A new electromyogram contradicted a previous one, showing no clear signs of neuropathy. The root cause could be linked to my back issues: severely degenerated intervertebral discs and now, it seems, spinal stenosis. This might explain the muscle atrophy in one of my calves, but I'm not entirely convinced by this theory. I can only manage the pain with daily Voltaren; without it, it's unbearable. Personally, I feel my symptoms resemble rheumatoid arthritis, even though the typical markers aren't present. I believe not all rheumatoid arthritis cases are linked to the same genetic mutation, so I’m still searching for answers. I’m happy to share my experience and connect with others facing similar challenges. I’ve tried various approaches, including modifying my diet (even attempting a carnivore diet), but haven't noticed any significant improvement. Currently, I’m trying magnesium to help with the widespread fasciculations, but after a week, there’s no improvement yet. I’m staying motivated and committed to finding a solution. Wishing everyone facing similar battles courage and strength.

  • @lauraperez-wb6qh
    @lauraperez-wb6qh 6 месяцев назад

    My husband has the exact same thing and has had it for years before covid, to this day we still haven't figured out what it is and doctors haven't told them nothing they claimed it may be neuropathy but we're not sure

    • @Oxynium
      @Oxynium 2 месяца назад

      I have twitching like this on both sides, in my case most likely the cause is spinal disc bulging out and irritating the nerves.

    • @DTownFresh82
      @DTownFresh82 18 дней назад

      ​@@Oxynium yeah but a lot of people get this all over. Mainly in left calf but can happen anywhere in the body even in the face. Since it's all over the body it has to be neurological

  • @fredericaboussafy5276
    @fredericaboussafy5276 6 месяцев назад

    I have had muscle fasciculation for about 5 months, it can happen anywhere on my body, it goes away and comes back,

  • @turkersoykan5695
    @turkersoykan5695 6 месяцев назад

    🧠♥🙏🏽

  • @Nabiyah1
    @Nabiyah1 6 месяцев назад

    These are not necessarily benign long term and are generally indicative of a mild to moderate nutrient deficiency (typically a vitamin/mineral). Do yourself a favor and get a micronutrient test. Some preliminary you should ask your provider to run (Mg RBC (not serum, unless you run both together. RBC is a more sensitive Mg test. Mg tests are poor preventative markers and don't really show anything helpful until the body is actually in trouble due to where the majority of Mg is stored in the body). Vitamin D 25 OH, *NOT the 1,25.* Tell Dr DO NOT code VIt D as routine, but as a followup for symptoms of possible deficiency, otherwise INS won't cover and it's ridiculously expensive for just one vitamin when ordered as _routine_. Of Course run a standard CMP. A CMP will pull your general labs like your Sodium, Potassium, and Calcium levels. These are the primary labs anyone should run first, and generally, one or a combination of these nutrients are deficient and are the issue. B Vitamins can also play a role if those primary minerals or Vit D not the issue and should be checked as well. These Vitamins/Minerals can lead to more dangerous symptoms if left unchecked and so ruling these out are a nice start to confirming a truly benign ruling rather than just an assumption, regardless if from a medical professional or not). Keep in mind, it hasn't always been there. The body doesn't just start doing things for no reason. It is trying to tell us something. What is the bigger question. Often times it's not a concerning condition, but that's no reason to ignore, since doing so only creates bigger issues, eventually. Best of Health to Everyone Reading This. May You Live, Long, Healthily, and Prosper.

    • @brokenman-f2t
      @brokenman-f2t 5 месяцев назад

      What proof do you have of what your saying? Some large study done on this exact condition and that's what they found? I doubt it. Keep your know it all Comments to yourself. I've had this for 15 plus years, it never stops, ever. Ive been to multiple doctors and specialists none of them have ever said what you are saying. They all have said it's benign fasciculation syndrome. Which I never agreed with because benign fasciculation syndrome is like your eye twitches for a day then goes away. This is non stop

  • @kristijwilcox
    @kristijwilcox 7 месяцев назад

    Thank you!

  • @Dani-D-Crusader
    @Dani-D-Crusader 7 месяцев назад

    Got a shot 2 months ago and the twitching will NOT STOP

    • @briangallagher6624
      @briangallagher6624 7 месяцев назад

      Can I ask where you were shot?

    • @Dani-D-Crusader
      @Dani-D-Crusader 7 месяцев назад

      @@briangallagher6624In both of my arms near my shoulder

    • @Dani-D-Crusader
      @Dani-D-Crusader 7 месяцев назад

      Both of my arms near the shoulder

  • @mary-vy3mo
    @mary-vy3mo 7 месяцев назад

    see "scalfari all ms is ppms"

  • @martinmatko6401
    @martinmatko6401 8 месяцев назад

    MS will lose make the possible look easy! Facilitate Multiple Sclerosis research!! Science confirmed medecal condition causative factors for Neurovascular Diseases Multiple Sclerosis and Covid 19 involve Chronic Cerebrospinal Venous Insufficiency (CCSVI) yet to be fully understood genetics and environmental issues such as infections or food/vitamin nourishment! Science confirmedcausative factors for Neurovascular Diseases Multiple Sclerosis and Covid 19 involve Chronic Cerebrospinal Venous Insufficiency (CCSVI) yet to be fully understood genetics and environmental issues such as infections or food/vitamin nourishment! Science confirmedcausative factors for Neurovascular Diseases Multiple Sclerosis and Covid 19 involve Chronic Cerebrospinal Venous Insufficiency (CCSVI) yet to be fully understood genetics and environmental issues such as infections or food/vitamin nourishment! So happens a protocol of treatment for MS and Neurovascular Disease is CCSVI Venous Angioplasty to fix mechanical Vascular issue and stem cell therapy to repair damage caused by narrow malformed leaky Veins! What is the role of CCSVI Venous Hypertension and proper/improved Cerebrospinal flow? Apparently Neurogenisis and Homeostasis side effects of Venous Angioplasty treating Neurovascular Disease CCSVI! ect., Ect., ECT.! As much the unproven autoimmune theory so called MS is being referred to as a slow Stroke! #BloodFlowMatters Keep in mind! Supplying Oxygen and Nutrients to every Cell in a Body, Blood circulation, including activity/exercise. Building Blocks of life, having made yourself what you are functioning today! Nothing else matters! Science!!! FB Group: MultipleStenosisSociety facebook.com/groups/493935520792751/?ref=sharec Apparantly nothing else matters critical Healthcare research facilitate collaboration defining the path forward establishing the understanding and treatment of Neurovascular disease organizing unified clarity in Science knowledge and progress! #CCSVI 'Fluid leaks from small blood vessels and collects in tiny air sacs in your lungs so they can’t fill with enough air' #microbleedings #BloodFlowMatters So happens CCSVI is a MINIMALLY INVASIVE TREATABLE Congenital Science Confirmed Recognized Medical Condition studies show causative factor so called Multiple Sclerosis and role/part 43 other so called Neurological Afflictions Including Migraines, Asperger Autism, Dementia/Alzheimer's, Aphasia, Optic Neuritis, Tinnitus, Transverse Myelitis, Parkinson's Disease, Lyme Disease, Meniers Syndrome, Ehlers-Danlos ect., Ect., ECT.! As much the unproven autoimmune theory so called MS is being referred to as a slow Stroke! #BloodFlowMatters Keep in mind! Supplying Oxygen and Nutrients to every Cell in a Body, Blood circulation, including activity/exercise. Building Blocks of life, having made yourself what you are functioning today! Nothing else matters! Science!!! FB Group: MultipleStenosisSociety facebook.com/groups/493935520792751/?ref=sharec Apparantly nothing else matters critical Healthcare research facilitate collaboration defining the path forward establishing the understanding and treatment of Neurovascular disease organizing unified clarity in Science knowledge and rogress! #CCSVI Establish Venous Cerebrospinal Blood flow treatment, as a primary care option treating Neurovascular Disease, eliminating the cause of disease SymptoMS!!! #CCSVI Multiple Sclerosis is strong and you often need help. Make you be worthy of this help, don't stand in a corner complaining, do your part! 💪 #Symptoms often ease/DISAPPEAR Facilitate Collaboration Neurovascular Disease Research! #CCSVI FB Group: MultipleStenosisSociety t.co/YYPIA4tRuM So happens, to mention apparently, Neurogenesis and Homeostasis, are often side effects of Venous Angioplasty treating CCSVI!! Apparently sooner treatment best possiblity Symptoms easing or disappearing. 1/1 #CriticalHealthcare_Research #CCSVI Cardiovascular/Neurovascular Disease including Heart function & Dopamine related Mental Health Depression Vascular Disease issues! #Vascular t.co/PdmbyVDbcy Time for Learning Science #BloodFlowMatters Apparantly nothing else matters critical Healthcare So happens CCSVI a TREATABLE Congenital Science Confirmed Recognized Med Condition STUDIES show causative factor so called Multiple Sclerosis & role/part 43 other SO called Neurological Afflictions Incl. Migraines, Asperger Autism Dementia/Alzheimer's Aphasia Optic Neurtis Tinnitus Ect! facilitate collhaboration defining the path forward establishing the understanding and treatment of Neurovascular disease organizing unified clarity in Science knowledge and progress! Have you tried learning about best possiblity to eliminate cause of SymptoMS! Can you relate? Connect with others who know about #CCSVI and #neurovasculardisease on FBGroup: MultipleStenosisSociety! facebook.com/groups/493935520792751/?ref=share WORLD CCSVI AWARENESS MAY 3 - 10 So happens CCSVI is a MINIMALLY INVASIVE TREATABLE Congenital Science Confirmed Recognized Medical Condition studies show causative factor SO CALLED Multiple Sclerosis role/part 43 other so called Neurological Afflictions! #CCSVI So happens CCSVI is a MINIMALLY INVASIVE TREATABLE Congenital Science Confirmed Recognized Medical Condition studies show causative factor SO CALLED Multiple Sclerosis role/part 43 other so called Neurological Afflictions! #CCSVI

  • @martinmatko6401
    @martinmatko6401 8 месяцев назад

    Who Knew?? #BloodFlowMatters Supplying Oxygen and Nutrients to every Cell along with clearing toxic brain waste, what is the role of CCSVI Venous Hypertension and proper/improved Cerebrospinal flow, impacting neurological symptoms regulating mood and cognitive Senescene Psych issues? #CCSVI #BloodFlowMatters With age, blood flow to the brain decreases b/c blood vessels produce less nitric oxide, a gas that expands blood vessel walls. Such disruptions contribute to changes in cognitive function that occur with age. #Exercise increases nitric oxide & boosts blood flow to the brain. #Urgent #BloodFlowMatters Horizontal sleeping causes Reflux of De-Oxygenized blood towards the stenosed Hypoxic brain, which after years results in MS Sleeping is a Silent threat to mankind! Keep in mind! Arteries are nothing without a Heart, and a Heart is nothing without Veins! Treatment improving Arterial Circulation is permitted and common, all treatments that improves Circulation in Veins are not widely available. #CCSVI So happens CCSVI is a treatable congenital SCIENCE CONFIRMED recognized Medical condition causative factor SO called Multiple Sclerosis & plays part/role 43 other SO called Neurological afflictions according to studies certanly Including along with other mysterious brain diseases with comparable Symptoms!? Help facilitate Neurovascular Disease Research Best chance for longevity quality of life depends on availability Neurovascular Disease Research Collaboration. '“When we age, one of the common things that happens within our brain is that the blood vessels do become compromised in part because of chronic conditions,” Liu-Ambrose said. “And when that occurs in normal aging, what happens within the brain is … silent strokes.”' As much CCSVI has been Scientifically established to have a role/part in 43 so Neurological afflictions including Dementia and so called MS 'There is evidence to suggest COVID-19 impacts the same blood vessels that feed the brain. If the virus is damaging those vessels, which could speed up aging, this, in turn, means some survivors might be at risk of getting early-onset dementia.' Time for Learning Science #BloodFlowMatters Apparantly nothing else matters critical Healthcare So happens CCSVI a TREATABLE Congenital Science Confirmed Recognized Med Condition STUDIES show causative factor so called Multiple Sclerosis & role/part 43 other SO called Neurological Afflictions Incl. Migraines, Asperger Autism Dementia/Alzheimer's Aphasia Optic Neurtis Tinnitus Transverse Myelitis Ect! facilitate collaboration defining the path forward establishing the understanding and treatment of Neurovascular disease organizing unified clarity in Science knowledge and progress!⁰⁰ Critical Healthcare Research addressing Neurovascular/Cardiovascular Disease including Heart & Brain function Amygdala Dopamine/Serotonin related Mental Health Depression Vascular Disease issues! #anxiety #VascularDepressionConsensus FB Group: MultipleStenosisSociety t.co/7JNmFD7W4l Apparently What is the role of CCSVI Venous Hypertension and proper/improved Cerebrospinal Blood flow Impacting circulation and homeostasis balance? #CCSVI #BloodFlowMatters #spasticity #perfusion Horizontal sleeping causes Reflux of De-Oxygenized blood towards the stenosed Hypoxic brain CCSVI is Science Confirmed Recognized Medical Condition STUDIES show causative factor MS Varicose Veins Fatigue Atrophy Inflammatiion Thyroid issues Covid-19 Heart function matters Cramps Mental Health problems Bowel & Bladder affairs insomnia Senescene Psych unusual behavior! Studies have shown that mostly ineffective often harmful or poorly tolerated Pharmaceuticals that 'TREAT' so called Multiple Sclerosis (M$) $20-40Billion W/a B/yr industry! Living with the Symptoms of Multiple Sclerosis is torturous tortuous tumultuous utter misery! Chronic Cerebrospinal Venous Insufficiency CCSVI/Neurovascular Disease CCSVI is a Treatable Congenital Scientifically Confirmed Recognized Medical Condition, Established Causative Factor in Multiple Sclerosis SymptoMS, AND plays a part 43 other so called Neurological afflictions! CCSVI may be impacting yourself right now and you are unaware! #CCSVI Apparently the Sooner a Person Receives Venous Angioplasty for Treatment of CCSVI! best possibility eliminating cause of MS Symptoms and easing or disappearing! So Called Multiple Sclerosis is more important to some than others Pharmacists, The M$ Society, Neurologists 'so called MS experts', Cane Manufacturing, Scooter and Power Chairs companies, etc Etc ETC So Called Multiple Sclerosis (MS) is/HAS been a MYSTERIOUS elusive UNPROVEN Autoimmune THEORY solely based on SYMPTOMS! STUDIES show Pharmaceuticals That 'TREAT' so called MS only 20-40% Effective DO NOT slow Progression of the Disease Often have Harsh Corrosive Side Effects sometimes DEATH! #CCSVI So Called Multiple Sclerosis (MS) is/HAS been a RUBBISH UNPROVEN Autoimmune THEORY Based Solely on SYMPTOMS! #CCSVI Venous Hypertensiono >microbleedings >iron >free radicals >neurodegeneration #multiplesclerosis M.S. - Mystery Solved Mysterious Autoimmunity = CCSVI Hypertension M.S. - Mystery Solved Mysterious Autoimmunity = CCSVI Neurodegeneration Keep in mind! Also venous hypertension ➡️ impaired CSF absorption ➡️ reduced G Lymphatic drainage ➡️ interstitial peptides accumulation ➡️ neuro inflammation #CCSVI So happens, to mention apparently, Neurogenesis and Homeostasis, are often side effects of Venous Angioplasty treating CCSVI!! Apparently sooner treatment best possiblity Symptoms easing or disappearing. 1/1 #CriticalHealthcare_Research #CCSVI Neurogenesis is the process by which new neurons are formed in the brain. Neurogenesis is crucial when an embryo is developing, but also continues in certain brain regions after birth and throughout our lifespan. qbi.uq.edu.au › brain-basic Homeostasis is an internal feedback system that stabilizes and balances our body's chemistry, so that our organs work smoothly and efficiently with each other. Sickness is the disruption of homeostasis, which doctors treat with medicine.Oct 20, 2016 www.bmj.com› bmj.i5643 Blowing the Whistle on Corrupt Pharmaceutical Industry by Gwen Osen FB Group: MultipleStenosisSociety facebook.com/share/p/jQxWX5Ce6sZgzmky/?mibextid=oFDknk #BloodFlowMatters Keep in mind! Arteries are nothing without a Heart, and a Heart is nothing without Veins! Treatment improving Arterial Circulation is permitted and common... FB Group: MultipleStenosisSociety facebook.com/groups/493935520792751/?ref=share_group_link

  • @martinmatko6401
    @martinmatko6401 8 месяцев назад

    Unproven or not widely available facilitate research!! Keep in mind! Arteries are nothing without a Heart, and a Heart is nothing without Veins! Treatment improving Arterial Circulation is permitted and common, all treatments that improves circulation in Veins ware not widely available. #CCSVI So happens CCSVI is a treatable congenital SCIENCE CONFIRMED recognized Medical condition causative factor SO called Multiple Sclerosis & plays part/role 43 other SO called Neurological afflictions according to studies certanly Including along with other mysterious brain diseases with comparable Symptoms!? Help facilitate Neurovascular Disease Research Best chance for longevity quality of life depends on availability Neurovascular Disease Research Collaboration. '“When we age, one of the common things that happens within our brain is that the blood vessels do become compromised in part because of chronic conditions,” it is said. “And when that occurs in normal aging, what happens within the brain is … silent strokes.”' As much CCSVI has been Scientifically established to have a role/part in 43 so Neurological afflictions including Dementia and so called MS 'There is evidence to suggest COVID-19 impacts the same blood vessels that feed the brain. If the virus is damaging those vessels, which could speed up aging, this, in turn, means some survivors might be at risk of getting early-onset dementia.' Time for Learning Science #BloodFlowMatters Apparantly nothing else matters critical Healthcare So happens CCSVI a TREATABLE Congenital Science Confirmed Recognized Med Condition S⁰⁰TUDIES show causative factor so called Multiple Sclerosis & role/part 43 other SO called Neurological Afflictions Incl. Migraines, Asperger Autism Dementia/Alzheimer's Aphasia Optic Neurtis Tinnitus Ect! facilitate collaboration defining the path forward establishing the understanding and treatment of Neurovascular disease organizing unified clarity in Science knowledge and progress!⁰⁰ Diagnosis SO CALLED Multiple Sclerosis? SymptoMS of the UNPROVEN AUTOIMMUNE THEORY MS often ease/DISAPPEAR when Science confirmed causative factor Symptoms recognized Medical Condition Chronic Cerebrospinal Venous Insufficiency (CCSVI) is treated with Venous Angioplasty! #CCSVI If only the availability Medical Scientific Clinical Trial Research! If you hadn't noticed..... DYK Apparantly..... So happens the original terminology 'Liberation Treatmenti' is that of the translation from Italian to English. Italy where the Medical intervention originated with Italian Dr. Paolo Zamboni Professor of Vascular Surgery from Ferrara University Italy. Being that the Venous Angioplasty treating CCSVI liberates or frees blood flow . Indeed the precise clinical expression for the operation is Venous Angioplasty! Matthew - CCSVI and his Liberation Treatment Matthew FB Group: MultipleStenosisSociety facebook.com/groups/493935520792751/permalink/1721248788061412/ Dr. Bill Code 2011 FB Group: MultipleStenosisSociety facebook.com/groups/493935520792751/permalink/1604156029770689/

  • @BranJo23199
    @BranJo23199 8 месяцев назад

    ALS

  • @didituki4881
    @didituki4881 8 месяцев назад

    🎹🎹🎹🎹🎹

  • @alexaalvarez4130
    @alexaalvarez4130 8 месяцев назад

    Hello, any updates on Elezonumab? Did the studies show any improvement on myelin? Thank you in advance

  • @DeanRamser
    @DeanRamser 8 месяцев назад

    Thank you, Dr. Giovannoni, for posting this video. Thank you for your research. We are 66YO. My wife has Secondary Progressive MS. Since visiting Europe (Aug-March this year) from Portland, Oregon, her symptoms have quieted. She has more hours of activity without fatigue and stabbing pain. We wonder if it is the food and walking? Also, we are considering moving to Europe. However, I am not sure if she will receive the same level of care she receives from OHSU. Which country has a strong MS research and treatment center? Thank you. Dean & Cindy

  • @eddyv6789
    @eddyv6789 9 месяцев назад

    Ive had this for a year now its not dehydration . Had serious health issues and stress may be culprit . Its mostly in calves and at night when i lay down . No pain just irratating . Also getting restless leg syndrome at same time

    • @spaceoddity54
      @spaceoddity54 8 месяцев назад

      Same here in the calves and feet. I find they want to cramp a lot too.

  • @mrd799
    @mrd799 9 месяцев назад

    I got this post covid, I never took the covid vaccines, i had it on entire legs, shoulders, arms, nose, all day long everyday, it was hell, now after doing water fasts 4 days, once every 2 months, and eating once a day 1 hour eating window, i got rid of it pretty much, havent had a twitch in two years except on the calfs, and not during the day only when i lay on my back to sleep, i get it but it's low intencity you cannot even see it and it doesn't bother me, and it's not even always only sometimes and exclusively on the calfs, it was way way worse to have it all over the body and all day, now i never have it during the day.

  • @taopaille-paille4992
    @taopaille-paille4992 9 месяцев назад

    Lifestyle (exercise) and diet play quite a big role in MS evolution (like a lot of diseases). It would be nice to take that into account for the studies. We can assume that those that use HSCT are maybe more driven than other patients to try decrease the evolution.

  • @Анна-д4х9ы
    @Анна-д4х9ы 10 месяцев назад

    Потрясающе интересно,новый взгляд на проблему рс,лечение!Спасибо большое

  • @MariafernandaAlmeida-e2t
    @MariafernandaAlmeida-e2t 10 месяцев назад

    Eu gosto de ver isso

  • @fazern4870
    @fazern4870 10 месяцев назад

    Много интересных тем дядя поднял.