Breast Cancer: A Deeper Understanding - Sanger Institute

Researchers have sequenced the genomes of 21 breast cancers and analysed the mutations that emerged during the tumours' development. They identified the mutational processes that lead to breast cancer. They found that these mutations accumulate in breast cells over many years, initially rather slowly, but picking up more and more momentum as the genetic damage builds up. These studies delve more deeply into the evolution of breast cancers, discovering a number of new mutation processes that can cause many thousands of mutations in a tumour, and drive its development.