The Hamster That Saved Thousands of COVID Patients
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- Опубликовано: 21 сен 2024
- Forget lab rats - meet the Chinese or striped-back hamster, an unassuming little rodent whose role in research over the years has led to breakthroughs in genetics, pharmaceutics and more!
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Cutting-Edge Drugs? Thank a Hamster!
Hamster Cells are Pumping Out Pharmaceuticals
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@whesley hynes 💯💯stop animal cruelty
@whesley hynes its the same as culling animals as food...
Wait but how were CHO's used specifically with Covid? Wasn't directly answered in the video, unless just click bait
@whesley hynes this is the same type of person that thinks milking a cow will kill it.
@whesley hynes i still dont see what your original statement has to do with scishow
My company makes the centrifuges that separate the CHO cells from the mature culture batches (2000 liters at a time) and holy crap science is way more awesome than most people realize. We owe a lot to the humble hamster and guys a lot smarter that I am who figured this stuff out.
Medical research is the reason why I subscribe to animal welfare, NOT animal rights.
The Chinese hamsters are displeased that a Syrian hamster was used in the thumbnail. Expect retribution
I'm impressed you know the difference.
Hamster dance song is now stuck in your head
if you had a hamster, it's pretty easy. both are really different
They used the right hamster in the original thumbnail, no idea why they changed it
@@Vulpovile prolly to cuten it
"...and most of them are made by hamsters"
I can't be the only one that thought of hamsters in tiny little lab coats making medicine in a tiny little hamster lab 🐹🔬
they need to get tiny lab coats for retiree hamsters or something
🤔🤔😂😂😂😂
SIMI hamster research lab. I wanna see it!
@whesley hynes did he watch the video they took samples of a hamster's ovaries and used those other than taking of the sample the hamster is fine
@whesley hynes sounds like a win win situation for me
My mom is dependent on one of the biologics from these hamsters!
She has an autoimmune disease, and she has had to go off the biologic a couple of times due to cost and insurances. (We are talking like 2,200 USD a month here so) And one unfortudent 4 month period without it she went from damaged but working knees to needing both knees completely replaced at 45!
These drugs are important, but remember they don't do any good if the people who need them can't get them!
"they dont do good if the people who need them cant get them" YEAH WELL THIS IS SOCIETY, its EXPENSIVE, cuz it takes a lot of TRAINING and CARE. please take note of this and dont comment about these things
@whesley hynes you are saying its good to see your loved ones pass away basically? :/ think better.
@@stefix1615 It is a society. A society is supposed to takes care of its people.
@whesley hynes So you are saying a hamster is more important than my mom. Okay well have fun with that.
@@emccoy yet it is expensive, too. ya know
whenever you're getting chemo treatment or getting a vaccine just remember a little hamster made it all possible.
Its cause they experiment on them and torture
@whesley hynes I mean, they’re just using the cells at this point.
@whesley hynes
No lunch is for free. Someone had to pay the price.
@whesley hynes it’s that or people. We’ve saved millions upon millions of lives from suffering, would you rather test a medication on a hamster, or on your mother? Your child? Think about that seriously.
Animals aren’t sweet innocent babies, remember they had trouble getting these hamsters to breed because they would literally rip one another apart.
I cleaned a hamsters cage once after she had babies because there was a little unsanitary blood in her cage from the delivery. Her response to that was to *eat every single one of her babies*
If a panda has twins, she generally decides one of them deserves death and refuses to feed or care for it.
Birds have too many eggs, one day apart, on purpose. Then they only feed the two or three strongest while the youngest starves to death while it screams for food until it is pushed out of the nest by its siblings or just wastes away.
Put away the Disney movies, the real world isn’t all peaches and sunshine and rainbows, and humans are a part of it.
You mean 🇨🇳
Man, I don't wanna complain because way too many youtube channels don't have their volume at the right level. But damn, when I learn something from SciShow, the WHOLE house learns something from SciShow lol
If only volume was a controllable thing...
@@MB-yf4lt dude ikr! That would be dope! I'll stay tuned in to SciShow because I know when someone figures it out SciShow will be reporting on it
@@davidbrown2704 i cant tell if your commited to the joke or just not realising what he said 😂
The thing is, where they have their audio is the correct place. They normalized their audio, making it where the loudest sound is near the loudest the speaker can give.
It's far better to do that than to have the audio too quiet and you can't turn it up (as you're using a Bluetooth headset or something). I hate it when I have to skip a video while using my Airpods becuase the video is just too quiet.
If I had my way, RUclips would automatically normalize audio. So even videos with their audio at -15db would sound just as loud as this one at -2db.
Sending prayers for all those hamsters that gave their bodies up for us humans to survive. Thank you little guys.
It's a cell line. They are not literally growing hamsters. At least not in this particular case.
Never forget.
@whesley hynes Quit your lying. You don't know a thing about this.
Yeah also thank the human babies that they put into vaccines...
Yeah, aborted baby cells are some of the ingredients, it's almost like old times with us sacrificing children so it would rain... Except now we are doing it in white lab coats, and doing the sacrifice for more complex things
it’s amazing how many mind blowing things exist without everyone knowing about them.
The more you know, the more you realize you don't know.
Facts- i wish more people understood =
You could call it mind blowing lol
Thats the only Problem! We know Everything, but we don't know how to Search for it
It's amazing how many scientific discoveries have been made through the hard work of so many people over so many centuries, and yet 99% of the populace just take it for granted and think it all grows on trees. Actually that would be a slight against the very small number of people who have actually grown trees. People taking insulin daily to stay alive because they ate themselves into morbid obesity also railing against the same scientific community who created insulin when they tell them to take a vaccine for a global pandemic. Or an ugly orange man who can barely read taking sole credit for a vaccine that took an army of people and decades of research.
"The hamster that saved thousands of covid patients"
Says not one word about covid
And somehow no one is mentioning it in the comments either!
@@SensitiveTrucker I know right?
Could be to avoid RUclips demonetisation? But then it's in the title, so...
@@bangscutter Just being in the title gets link spam below the title that leads to WHO and localised health authority info pages. As expected the WHO link is ineffective.
Covid-19 causes a kind of pneumonia. The hamster biologics help against the pneumonia.
Those kids probably don’t even know they played a part in such a huge scientific advancement
Well yes, because they're dead by now
Luckily the hamster weren't eaten. Rip those kids. Instead of shitty reddit memes, they saved lots of people.
@@RoastCDuck Eaten? they were being sold as pets
@@robrod7120 it was in china , probability of them being sold to be eaten were equally high
@@apatriot6421 haha chinese eats everything that moves very funny
But really though, the mice that are eaten are mostly grown in farm and not pet, same with dogs and cats
I really appreciate the contribution these little critters have made to science because last year targeted chemo cleared up the cancer tumor in my right lung. Good going guys!
Just to clarify: all these CHO cells came from one hamster? That's .... amazing.
Pretty sure all cell lines are from the one individual animal they originate from.
What is amazing is that this cell line will probably outlive the hamster.
One big hamster
I saw this comment before I watched the video and i was like.. carbohydrate cells 🤣?
It's like the story of the HeLa cells which were a cancer tumor on a girl named Henrietta Lacks which never stopped dividing and still exist today helping many studies, except with a hamster.
Did I miss the part where you explained specifically how hamsters saved COVID patients?
We all did.
I read in the NY Times about experiments with hamsters to test the efficiency of mask material. Basically, they had mask material between cages and infected hamsters on one side and healthy hamsters on the other.
They also used hamsters in vaccine testing. Hamsters apparently get seriously sick when infected with Corona, they are the model for bad cases of Covid.
Last summer I had a cough that I first thought was Covid and I was worried not only about myself but also about my pet hamster. I was so glad when my test came back negative.
One word: antibodies. I think they didn't want to mention the word COVID because by now we're expected to all know what the connection between COVID and antibodies is. After all, artificially grown COVID antibodies are currently used as a treatment for patients who get it bad.
Yeah, very interesting but I missed the COVID part too.
@@trishapellis It's confusing, though, because the so-called vaccines being used now aren't traditional vaccines- killed virus- they're injecting things one might classify as proteins. I know RNA is pretty complicated, but it's still a protein, right? And I think one of the vaccines actually does simply find a way to insert copies of COVID-19's spike proteins directly into the body... I may be misremembering that. So I thought he was going to say the hamster factory was being used to produce those.
Very frustrating, because I was going to share this video with a lot of people, but I can't because it's missing the crucial point: that the mechanism/process they're using to create the COVID-19 vaccines is NOT new and experimental, but has been in use for decades; all they've done is programmed the 3D biologics printer to spit out a differently shaped protein.
... Except maybe the hamsters cells aren't being used to make the vaccines after all; maybe it's just the monoclonal whatsits? I don't know.
Hamsters when the scientists tried to put them together so they'd breed: *Virginity shields activated*
Rated R for extreme violence, not sexual content
asian moment
They probably put them in a tiny cage at first, and the American scientists figured out they needed more space to avoid aggressive behaviour.
@@kellydalstok8900 also can only be one female, and *also* the female needs to be sexual receptive at the time. And even then, she can still decide she just doesn’t really like that particular male, and you’ll find her the day later gnawing on his bones to help with her teeth wear.
More like virginity swords since the issue was the hamsters immediately trying to kill each other...
make sure you care for your pet hamsters properly there’s a lot of misinformation about them
Omg yes there is and many things marketed towards hamsters at pet stores can be dangerous
@whesley hynes Thankfully now of days they don't. These are just their cells which can be produced in indicators or what not. Not from any more hamsters "saficing" for them.
also their omnivores so buy crickets for them.
They need so much more space than any pet store claims. I have to build my own hamster cage because I can't buy a commercial one large enough for a Syrian hamster, they run 5 miles a night in the wild.
@@raccoontrashpanda1467 if you can be arsed to upload videos of that to RUclips, it would be pretty cool. Happy pets is always quality content for the internet.
Oooo I just looked it up and my medication, Adalimumab (Humira), is made in CHO cells
That's sooo cool, I didn't know before
Used to inject that
Every medication that ends in "-ab" is an antibody and all of them are currently made in animal cells, mostly CHO cells.
Though currently were working on humanizing insect cells to produce the right glycosilation patterns to produce those drugs cheaper and more easily, because damn mammal cells are a pain in the ass to care for...
Interesting, I'm using Humira for years and never thought it was made using hamsters cells hahaha
@whesley hynes Animal rights nut. Go get sick stupid.
@whesley hynes Humira is made from cell culture, not living animals.
I like to think that hamsters are actually the most powerful beings in the universe, but wilfully choose to be tiny and cute to decieve the dumb humans.
Have you read the Hitchhikers Guide to the Galaxy in that its white mice who act as lab mice to teach humanity things. They don't suffer as they aren't actually the mouse but Psychic beings who just use the bodies as a shell.
Delete this before they realize you are on to them. Hide man, hide! They are coming for you!
I always think like this about my pets
GO FOR THE EYES BOO! GO FOR THE EYESS!!
This is why you should always treat your pets good and you may survive when they take over lol
I have a Chinese hamster who I love. They aren't the most friendly type of hamsters though, it makes sense they were bred as lab animals not pets 😅
I had a Chinese hamster his name was whiskey. He was very sweet and was easy to handle. I had him in high school I miss him
I had two but I was a f*cking idiot; I kept them in the same cage and one night Ham (grey with white belly) killed Stir (black with white spots)... :( both were cute af and came from the same litter.
Really depends on the hamster, not the breed. I have two Russian dwarf hamsters and they naturally aren’t cuddly but one of mine hates being touched and the other is very friendly and likes to be pet while he eats. The younger you get them the easier they are to tame. Pet store hamsters also have horrible genetics and are treated bad so if they come from there, they’re more likely to have a hard time being tamed.
Tbh, Rodents can vary a LOT in behavior.
@@alexwang007 lol you named them ham-stir that's great
Type-1 Diabetic here, diagnosed in the early '80s. What we now call the "A1c" test, used to be called "Glycosulated Hemoglobin" test. This video is the first time I've seen that term used outside of the name for the test I have taken 4 times every year, since the 80s!
Chinese hamsters were also used to develop some type 2 diabetes medication. The sad thing is that this knowledge didn't really cross over to the vet community. Some pet hamsters also develop diabetes and owners want to treat them. About 12 years ago the moderator of a large US hamster forum researched this and later I "imported" this knowledge into the German speaking hamster fancier community. We treated several of our pets with pills made for type 2 diabetic humans based on research done with Chinese hamsters. Thank you, Chinese hamsters, you gave several of my Campbells dwarfs an extended life.
Sorry to let you know but glycation and glycosylation are not the same thing
I'm a type 1 diabetic also, I can't wait until they develop a fully closed loop system...
Or just freaking cure it already, I'm so sick of it
@@amineaboutalib Not sure I understand your comment. No one said anything about glycation.
@@catatonicbug7522 Hemobglobin is glycated not glycosylated, so they're not the same thing
I muttered, "Brilliant!" out loud when you described how scientists get the desired genes into the CHO cells' nuclei. Really, really brilliant! (6:43)
CHO cells: We came from a hamster, of course we won't accept your dirty human genes wtf.
Scientists: *extortion time*
@@khango6138 Hahaha! That's hilariously accurate! 🤣
Biologics are incredible. Infliximab saved my life, no exagerration.
Hamsters keep saving my life.
I love how all of this came about by one scientist going "Eh. Might as well give these a go".
Trying something different due to circumstances literally changed the world.
I wish scishow would grow more, when I have kids I feel like they would learn more if everything was presented in this fabulous fashion
Sadly this is what most people think learning means. No, it's doing stuff.
Thanks for clearing that up. There was a recent report from one of the larger western media that titled it in a way that suggests Chinese people are doing weird things with animals, this time, with hamster ovaries. Little do they know that this is the universal practice in the modern pharmaceutical industry. I guess there’s a reason why they majored in journalism.
"I guess there's a reason they majored in Journalism" SHOTS FIRED
So cool! Thank you hamsters!
*hamster
I love that we have CHO cells from hamsters and HeLa cell line from Henrietta Lacks (though that wasn't a great story).
@whesley hynes we also torture unborn children, ripping them out of the womb limb by limb and then crushing their brain in...
And then we go and put their cells into things like vaccines
Thank you, cute tiny hammies 🐹
Nicole on compressor
Nicole on delay
@whesley hynes Stop spreading misinformation
so much we owe to those creature!! So, we toast to the unknown helper of humanity, thank you xhamster!!!
So cool! I never even considered how they’d go about this.
Engineering biological organisms to do certain tasks is such a groundbreaking discovery for the medical field
Like the internet needed another excuse to love hamsters
I can’t believe hamsters who owe us our lives are now GETTING KILLED by us in Honkon….. We need to respect these lil guys more, especially rodents.
Meanwhile, my hamster bit me for the first time and it bled a lot. Now I know why she got an attitude. If she can talk she'll probably talk on an on about how her ancestor saved us to justify the biting.
Harvey, Harvey
Harvey the Wonder Hamster
He doesn't bite and he doesn't squeal
He just runs around on his hamster wheel
Harvey, Harvey
Harvey the Wonder Hamster
Hey, Harvey!
-Weird Al Yankovich
search _Harvey the Wonder Hamster_
When I was a kid in Beijing, I would see overstock lab rats and rabbits being sold as pets, by the caretakers of animal labs. It's come full circle.
Btw, when I was a researcher in the US it was standard practice to put to death the animals that are over a certain number of weeks in age. Sometimes it can be because the materials you ordered didn't arrive on time, or your cell culture failed.
Thank you for calling out inhumane lab practices.
There are small animal rescue organizations in Germany and Austria who will take overstock lab animals and find pet homes for them. They have a hard life because some radical animal rights activists blame them for "enabling" lab practices. And they have to keep their lab contacts basically secret because otherwise some people would harass lab workers...
Sooo, pharma got rich on the backs of those poor hamsters?
Hamsters? Easy?
They’ll pass away if you stress them.
“I swear man, it’s not mine! It’s the hamsters”
Strange how insulin production is simple and yet it's insanely expensive.
Thank you soooo much for making such a detailed explanation! Biochemistry is all about the details.
@whesley hynes Would you find the study of biochemistry in the context of food science interesting?
A Chinese hamster cell line tagged with an acronym that is also a Chinese surname. How fitting!
Could have done without the clickbait: content is interesting enough as it is
Title mentions hamsters saved covid patients. In fact, it was some hamster cells scientists used in labs and altered themselves. Oh, and covid wasn't mentioned once.
@@moonshot9056 Wasn't getting upset, but as Catalin stated, covid wasn't mentioned once. It was a good episode; don't get me wrong. CHO cells are a damn fine biological cheatsheet & I'm happy to know of them.
@@moonshot9056 Cool man, enjoy your day
"They're called biologics. And most of them were made by hamsters." STOP RIGHT THERE. I choose to believe this is where the information ends.
@whesley hynes all the CHO cells came from 1 hamster in 1957
@whesley hynes Tortured? You mean euthanized to harvest her eggs. I'm gonna go out on a limb and say you're a member of PETA.
When a hamster has achieved more then you:
been spending most our lives living in a hamster's paradise
God bless you hamster
@whesley hynes it is. He died with purpose and helped countless lifes
I love how all the sources are in the description. Nice work!
Yeah. Those little Hamsters can be aggressive towards each other. I used to have a couple of Hamsters, as pets. A male, long-haired, cream colored Hamster, named Simon. And a short-haired, brown/white haired female, named Abby. They were kept in the same cage until Abby turned up pregnant.
Their first litter of babies was adorable.
i just started a biologic for rheumatoid arthritis. i guess the fact that its made in hamsters somewhat explains the six thousand dollar price tag
@whesley hynes you go first then.
me remembering my hamster; she died of ovarian cancer...RIP my favourite escape artist
The bass line at the beginning of the song that starts the video is dope as hell! 🔥
Literally just transfected HEK cells in my uni's lab today. First time ever trying to engineer mammalian cells. This was perfect timing!
I'm guessing CHO stands for Chinese Hamster Ovary, because scientists don't have lots of extra time to give everything creative names.
WHY AM I JUST FINDING OUT ABOUT SUGAR PATTERNS NOW?!?
Organic chemistry 1 and 2, and bio 1 and 2 and 3, never taught that different species have different sugars.
ditto
It's a biochemistry thing.
Interesting to know the history of CHO cells. Good recap for me remembering cell culture class from my biotechnology degree.
@whesley hynes Whatever, but a lot of people are saved everyday thanks to biological drugs (e.g diabetic people, trombosis patients...). Biotechnology is evolving in a way that every day less and less animals are used in clinical trials.
Love your guys content! Makes me feel smart when I understand most of it😂
Hemophilia runs in my family. I have it, but don't need treatment unless I get into an accident. My brother's however do need treatment and apparently for a time (before transitioning to the new medicine), their old one was made using this weird hamster tactic lol.
I was almost expected that TikTok hamster featured on Last Week Tonight that showed how to wash hands.
Weird, why do two tiny rodents who seem so similar have such a huge difference in the numerous of chromosomes
This is gonna be in your reccomendations
This hamster shall be remembered for his sacrifice
Love the bio content, keep it coming!
@whesley hynes Until someone finds a better way. That someone could be you! The more people we have working on the problem the faster we'll find a solution. Become a biologist! Develop cruelty-free protocols!
Hamster deserve the Nobel prize.
This was very well explained, thank you!
Dude. You been working out?
Thanks for helping understand what's going on at my new job
Original title: Cutting-edge drugs? Thank a hamster!
And the next noble prize goes to. . . (Silence for dramatic effect). . . . . Hamster's cells!
this help so much for my homework thanks
9:14 Some kids were selling some hamsters in the street,
that just happened to have a low chromosome number and human-like sugar pattern on their proteins.
But sometimes, that's just how Science works.
No, that is not Science, that is Chance, that is Luck, that is God, he gave humanity a gift.
I have pet hamsters; one of which is a Chinese hamster. He's a weird little dude; and I love the hell outta him. Even more proud now.
Thank you hamsters, rats, and every other animal we enslave in order for us to survive!
Drop your childhood (or current!) hamster names here! Mine was Puff Mufasa Cook, the Magic Hamster :)
That is a great name!
My hamsters were Martha and Donna, my favourite companions from Dr. Who.
Chucky, after the Rugrats, cus he had spiky red hair .
Come to think of it, maybe he was a guinea pig lol
At first he was "owwe you little *#@#" he later became Mr Morris.
An ex girlfriend had three hamsters named Phoebe, Monica and Rachel. One morning she found that Rachel had killed and eaten most of the other two.
Whipple, Ginger, Buzzkirk.
Ah, Chinese Hamsters. I've had two of them, they are truly the best type of hamster.
@whesley hynes scientists torture many animals, but it normally ends up advancing humanity...
I'm more bugged by them killing human babies
@whesley hynes there are many people alive today that wouldn't be without animal torture..
To me it's bad for them to do that to animals, but I also understand when the end result can change the quality of life for some people...
It's something that is needed to help our own kind.
@whesley hynes well, it's going to continue to happen no matter what..
The information is too valuable for them to stop
@whesley hynes and if it means getting rid of diseases I'm personally all for them doing it..
I have type 1 diabetes, and I'm sure they are using animal torture looking for a cure..
They are also trying to cure cancer using it.
I would be more worried about how our food is produced, then lab animals...
Cows and chickens and stuff are tortured too, and lobsters and shellfish are literally boiled alive.
Our food chain causes far more harm to animals then our scientific process, much of the time it's only mice used in experiments also...
To me that's better then cows and large animals
Wow, this one is one of the best episodes, thanks for your work guys.
I'm glad these hamsters are helping people but it's sad that we have to use them still :( I hope one day soon we can move beyond using live animals in science
I'm fairly sure that the CHO cell line is clonal and came from just one hamster, Henrietta Lacks style, so that's good at least.
But yeah point stands, still plenty other little critters gettin the pointy end of science and that's a bummer.
1:52
The way he pronounce E. T. Hsieh I found to be hilarious!! He probably pronounced it correctly, at least it sounded correct.
No. It's not even close xD. My jaw dropped since I thought Stefan could probably pronounce it, a very common Chinese surname.
Wade-Giles romanization sucks. Completely unintuitive for nonlinguists. It's Xie in pinyin.
That's just how hamsters roll
Off topic but- I always find it adorably fing FASCINATING that hamsters are roam free as wild rodents kn Europe. If I were European I would be so tempted to set out hamster tubes and wheels and balls and water bottles and see if the “woodlands” version enjoyed the toys as much as my pet hamsters when I was a kid.
European hamsters are about twice to three times the size of a typical syrian hamster. They're not going to fit in most of those items (they're typically too small for syrians anyway, or not good to use, like the balls) But it might be fun to make little houses and hides for them. They can be pretty vicious too. But they are very cute.
If you want to see European hamsters, come to my channel. Haven't updated in a while but might start to do some more videos this year. The season is just starting (they were hibernating until recently), I've been able to shoot a couple of photos last weekend but no video yet.
go hamsters!
Hamsters are NOT easy to care for. The minimum amount of space required for hamsters in the US is 450 square inches. That is the size of some desks you can buy at IKEA. Hamsters also need tons of bedding, toys, hides, large enough wheels (8-10 inches in Chinese hamsters), food, herbs, hay (nesting material), and clean water. Hamsters may be small but if you want a happy hamster, give them AT LEAST 450 square inches. I am sure these labs don’t know what their hamsters need and that they are abusive and insufficient.
It has NEVER occurred to me that hamsters are wild animals somewhere
Thank you
TYSM HAMSTERS!!
Time I learned that hamsters are so rabid they will fight to the last if not separated
So this was the ultimate fate of Hamtaro
Hamster Power!!
The unsung hero
01:52 that pronounciation was nice
Using a deadly bacteria to make a life-saving protein is so metal
Hamsters are underrated
Thank you hamster
penelope, bijou & pashmina the real mvp's
Hamsters are not easy to keep, they’re needy little creatures. The vast majority of hamsters kept as pets are in straight up abusive enclosures with unsafe equipment. They need 450 sq in CONTINUOUS floor space at a bare bare minimum, really 600 is the minimum that should be used. Wire wheels are cruel and will injure a hamster, wheels should be plastic or wooden so they cant catch and break their feet. 10-12 inch diameter for Syrians, 8-10” for dwarf hamster species, anything less is cruel. Even the cages marketed as XXL by pet stores rarely meet the minimums, and cost a lot more than a homemade cage of the appropriate size (seriously, it can cost a lot less to make a larger suitable cage than buying an abusive one from a pet store). Research the needs of a pet before you get one.
I didn't expect to learn that Hamsters murder eachother
do a video on myotragus balearicus (the cold blooded goat)/cold blooded mammals
This video should end with the Hamster Dance.
5:35 is a.... flux capacitor
Before 1982, I was taking a mixture of pork and BEEF insulin. Both were being used.
How is it that I am only now learning the importance of glycosylation?