How to find Protein Sub-cellular Localization? | WoLF PSORT & BUSCA | Lec. 419 | Dr. Muhammad Naveed
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- Опубликовано: 21 авг 2024
- Protein Sub-cellular Localization by WoLF PSORT & BUSCA:
WoLF PSORT weblink: wolfpsort.hgc.jp/
BUSCA weblink: busca.biocomp....
About WoLF PSORT
WoLF PSORT predicts the subcellular localization sites of proteins based on their amino acid sequences. The method, which is a major extension to the venerable PSORTII program, makes predictions based on both known sorting signal motifs and some correlative sequence features such as amino acid content. Like PSORT and PSORTII, WoLF PSORT displays some information about detected sorting signals which is useful in helping users determine the reliability of the prediction in specific cases. Our experiments (paper in preparation) show that the overall prediction accuracy of WoLF PSORT is over 80%. For common localization sites (e.g. cytosol, nucleus, mitochondria, etc) WoLF PSORT makes better than majority classifier predictions even for queries that do not have strong sequence similarity to any sequence in the dataset. Thus WoLF PSORT is a useful complement to tools such as BLAST. The current dataset used to train WoLF PSORT contains over 12,000 animal sequences and more than 2,000 plant and fungi sequences respectively. It was gathered mainly from Uniprot but several hundred Arabidopsis thaliana sequences from the Gene Ontology database were also included.
About BUSCA
BUSCA (Bologna Unified Subcellular Component Annotator) is a web-server for predicting protein subcellular localization. BUSCA integrates different tools to predict localization-related protein features (DeepSig, TPpred3, PredGPI, BetAware and ENSEMBLE3.0) as well as tools for discriminating subcellular localization of both globular and membrane proteins (BaCelLo, MemLoci and SChloro).
About Dr. Muhammad Naveed
(HoD, Biotechnology, University of Central Punjab, Lahore)
With distinction, Dr. Muhammad Naveed obtained a Ph.D. degree in Biotechnology (Genomics & Bioinformatics) from Quaid-e-Azam University, Islamabad. He has won Ph.D. indigenous & IRSIP scholarships from HEC. He has done Pre-Doc research at the University of Ghent, Belgium. HEC awarded him the best Ph.D. (IRSIP) Scholar of the Year in 2013 & QAU honored him as a “Distinguished Alumni” in 2017. He is doing research projects in Bioinformatics, Molecular Biotechnology, Nano-informatics and vaccine designing, and Drug designing against infectious diseases. He has supervised 90 MSc. and 80 MPhil. & 02 Ph.D. students. He has published 152 Research articles with 1186 impact factors, 6260 citations, 01 book, 06 book chapters, and filed 05 Patents. He was awarded the distinguished “Researcher of the Year” in 2016 (UoG) and 2018, 2019 & 2021 (UCP).
Contact links:
1. Official website: ucp.edu.pk/mem...
2. Facebook: / drmuhammadnaveed22
3. LinkedIn: www.linkedin.c...
4. Instagram: / prof.dr.naveed
5. Google Scholar: scholar.google...
6. ResearchGate: www.researchga...
7. Twitter: / naveedqau
#protein #cellular #wolf #localization #bioinformatics #drmuhammadnaveed 
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Thank you Sir! i am glad to subscribe you where i know latest tools regarding bioinformatics...stay blessed
Thanks and welcome
Also tell the sub-cellular localization of protists protein
dear sir also make a full series on biopython
done and search on my channel
Hello sir.thank for informatic video.Sir which tools or servers can be used fro virus proteins cellular localization
can use PSIPRED
@@Prof.Dr.MuhammadNaveed Aoa sir,can you mention any tool to convert cgids from metgylation dataset to gene name
NICE! But what is the significance of doing this??
To know about the protein functions and mechanisms of action
Slam sir . Sir mj AP sy pochna tha k KSA k scholarship mn parents ki details ka column hy pr jin k parents ni Hain wo wha Kiya likhain bcz gamuardian ka option e ni hy
can write parents detail