Metabolism | Regulation of Glycolysis

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  • Опубликовано: 30 сен 2024

Комментарии • 876

  • @Smoovek1d
    @Smoovek1d 5 лет назад +1059

    Man, teaching is a lost art :/ You guys are exceptionally talented in simplifying perplex information and teaching it in a way that is understandable to all. No matter how long these videos are, I know I'm not wasting time because I will fully understand everything by the end. Kudos to you guys for being a resource for higher learning students across the world struggling. Your hard work doesn't go unnoticed!

    • @nicolekellum6374
      @nicolekellum6374 4 года назад +7

      teaching really is a lost art

    • @mathematics5573
      @mathematics5573 2 года назад +1

      Kevin As a biochemist, I think he is very over complicating Glycolysis. Not a good video. Sorry.

    • @Raveio-hr3zr
      @Raveio-hr3zr Год назад +3

      Nah, the video is perfect. It covers everything we need to know for school, even the arsenate problem.

    • @mrd2500
      @mrd2500 Год назад +1

      @@mathematics5573 Make a better video then. Let’s see what you got.

    • @mathematics5573
      @mathematics5573 Год назад

      @@mrd2500 I'll try. Already done some. His video isn't as bad as I made out. But he brings in too much irrelevant stuff.

  • @hemberry_
    @hemberry_ 11 месяцев назад +2

    I'm currently studying medicine in my fourth language (which is a heck of a challenge honestly) and your lectures are an awesome support for a much clearer understanding of... well, everything! thank you so much!

  • @snyld
    @snyld 4 года назад

    You are the master thanks! The way you talk and your pronuncing is so good to understand.

  • @jennifernwaonumah2702
    @jennifernwaonumah2702 3 года назад

    I love your videos soooo much. I subscribed from the very first video. You guys are amazing, you don't understand how much you have helped me in all my classes. Thank you for being so amazing!!!!!

  • @nutricionistadanielasalgad3383
    @nutricionistadanielasalgad3383 4 года назад

    Your videos are just outstanding. SO glad i´ve found your channel. It´s so helpful! Thank U

  • @ratikantaojha3392
    @ratikantaojha3392 2 года назад

    Your notes are superb and amazing

  • @slowedguy73
    @slowedguy73 8 месяцев назад

    Im so happy ur alive

  • @zanyarqadir6625
    @zanyarqadir6625 5 лет назад

    thanks man for all your videos
    you are great 👏🏼👏🏼
    love you from iraqi kurdistan❤️

  • @lara-cm1lr
    @lara-cm1lr 3 года назад

    omg thank you so much y have no idea how much you help

  • @يزنخنفر-ش3ت
    @يزنخنفر-ش3ت 4 года назад

    amazing ! greeting from Russia !

  • @bushraliaqat9522
    @bushraliaqat9522 5 лет назад

    Sir u r a legend

  • @darcysanders7082
    @darcysanders7082 Год назад

    Thank you!

  • @hannahdivic28
    @hannahdivic28 4 года назад +3

    14:55 oh NOW comes the complicated step?? I thought that’s what we’ve been doing 😂😂

  • @MK-be3yh
    @MK-be3yh 2 года назад

    Do insulin really enter the nucleus to inhibit glucokinase/glucokinase expression? Isn't insulin a peptide hormone which binds to cell-surface receptors? (The same applies to glucagon as it is also a peptide hormone.)

  • @arwaafridi6708
    @arwaafridi6708 3 года назад

    Thankyou sir

  • @hossnaras6072
    @hossnaras6072 2 года назад

    perfect

  • @kiranliaqat1948
    @kiranliaqat1948 2 года назад

    Why pyruvate kinase step is irreversible? Why can't it be simple reversible by adding Pi to again form PEP from pyruvate in gluconeogenesis

  • @naommo5604
    @naommo5604 6 лет назад +442

    binge-watching the entire metabolism videos coz i have exam tomorrow

  • @vanjaplavsic296
    @vanjaplavsic296 6 лет назад +904

    I don't usually comment, but this is exception. I have my biochemistry exam next week and must learn 400+ pages. This videos are lifesavers! I'm a visually learning type of person and your style of teaching brings all this to a whole new level for me. Thank you and God bless you. Greeting from Croatia.

    • @marta6755
      @marta6755 5 лет назад +7

      Hi! I am in the same situation now. :) I am also from Croatia. Nadam se da ti je dobro prošao ispit. ;-)

    • @ficamica1
      @ficamica1 4 года назад +2

      Lepo receno, bukvalno isto, mnogo pomaze kad ga vividno objasni

    • @Ai-ChingChen
      @Ai-ChingChen 2 года назад +3

      Lifesaver is no exaggeration !!!

    • @blackphoenix9680
      @blackphoenix9680 Год назад

      400 pages?!!! Have you passed?

    • @jonesmuchindu1468
      @jonesmuchindu1468 Год назад

      😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊😊

  • @notanurse2373
    @notanurse2373 6 лет назад +255

    ANOTHER person who learned more in a 30 min video than weeks of reading the freaking book. Also, every time he says "ninja nerds," it sounds like he's saying "engineers." Anyone?

  • @thedrumacademy
    @thedrumacademy 5 лет назад +197

    I'm an older guy who is not at all scientific, but stumbled across your channel some months ago and have found your lectures fascinating. I just pick one and watch it to death...probably 20 or so times and then move onto another one. After a while I start to understand where each one is going and I then can start to appreciate just how amazing these functions and mechanisms really are. I wouldn't have thought it possible that anyone could retain this amount of information and disseminate it in such a fluent and digestible way...what a talent you have! I Stopped buying a TV license several years ago as I find video series like this so much more stimulating than a lot of the BBC output. I don't know why Google doesn't launch distance learning qualifications with such a wealth of incredible material. They could rival the likes of the Open University and it would be great if they could undercut the Universities making further education a bit more affordable for people in their 50's like me who are still curious and want to remain stimulated and challenged. Thanks so much, I really enjoy your work!!

  • @yohannesgemechu8854
    @yohannesgemechu8854 4 года назад +106

    I am a Biochemist and Immunologist by profession; I found this lecture pretty amazing. You have explained glycolysis and its regulation in a wonderful way. Keep it up, buddy!

    • @jobrown8146
      @jobrown8146 Год назад +2

      Thank you for providing your assessment of this video. As a learner just for fun at 65 years old, it's good to know that the information being presented is correct.

  • @Dominique4141
    @Dominique4141 6 лет назад +139

    This is literally the best explanation I have ever seen for carbohydrate metabolism. You have just made Graduate level Medical Biochem easy.

  • @Charly2063
    @Charly2063 4 года назад +85

    you are literally saving my life in med school!!! what would I do without you!! THANK YOU SO MUCH

  • @noorhussein4672
    @noorhussein4672 5 месяцев назад +10

    سبحان الخالق الذي خلق أجسادنا بهذه الدقة والجمال والإبداع، سبحان الله!!
    شكرا ninja nerd على هذا الشرح

  • @maarijsaeed2117
    @maarijsaeed2117 3 года назад +42

    I'm a first-year dental student and I wish you were my biochem professor. All year long I couldn't focus on this dry subject but your videos helped a lot. The way you explain the pathways in order is so helpful for visual learners. Please keep making more videos.

  • @cynashine4950
    @cynashine4950 Год назад +3

    If u weren't here...god knows what I'd do in my med school...

  • @dr.rahuldebnath622
    @dr.rahuldebnath622 6 лет назад +61

    man you are literally very creative... you have the best teaching skills ive seen so far... maintain your awesomeness bro ;-]...
    thanks for being in youtube... u are really a boon for many students incl. me.. keepit up

  • @kiffe22
    @kiffe22 4 года назад +27

    I am just watching this out of interest in the topic and I am so glad that I don't actually have to remember any of this.
    Good luck to everyone who has to know this or write an exam on it soon!

  • @jazlynamador5889
    @jazlynamador5889 7 лет назад +61

    I love how you made the bifunctional enzyme friendly with happy faces. They don't look as daunting anymore. Nice touch!

    • @NinjaNerdOfficial
      @NinjaNerdOfficial  7 лет назад +20

      +Jazlyn Amador lol I'm glad you enjoyed the video and I hope it helped. Thank you for your kind words!!

  • @laurenmarie8757
    @laurenmarie8757 Год назад +17

    “This is where your death awaits you” 💀
    Hilarious how he knows exactly what we are feeling. This part of the video is exactly why I came for your rescue. You’re amazing. Thank you so much! ❤

  • @alex-e7f9e
    @alex-e7f9e Год назад +9

    'woo this marker stinks' 😁 I love all these little ninja nerdisms in your videos, brings some human into teaching such complex topics. Your lectures have saved my brain, I have ADHD and reading six pages of text with no visuals to try and explain this process was NOT working at all for me.
    If you teach in a school/university they are very lucky to have you

  • @michaelatimmerman9553
    @michaelatimmerman9553 Год назад +14

    I just want to say thank you for all the help. I’m currently in grad school and Biochemistry is kicking my butt, but thanks to your videos I am finally understanding it. It says a lot when you are a better teacher than a graduate professor. Anyways, thank you 💛

  • @mariapaulapinerosclavijo7547
    @mariapaulapinerosclavijo7547 6 лет назад +8

    OMG THE BEST !!!!! I have learned more watching his videos then listening to lectures!!! 1000000000000000X LIKES !!

  • @habibecolak4985
    @habibecolak4985 6 лет назад +18

    Thank you so much these videos are helpful. you're a perfect teacher who I have ever seen

    • @NinjaNerdOfficial
      @NinjaNerdOfficial  6 лет назад +3

      +Habibe ÇOLAK thank you so much for your kind words I'm so happy that we were able to help!

  • @jnnaify
    @jnnaify 5 лет назад +7

    your BBB Kids Lips.... came in handy on my last exam. Thank you!

  • @saikrishnashashank1778
    @saikrishnashashank1778 6 лет назад +13

    Love the way you teach man! I see so much logic when you teach and that really helps! Keep up the great work

    • @NinjaNerdOfficial
      @NinjaNerdOfficial  6 лет назад +5

      +Saikrishna Shashank awesome I'm so happy we were able to help!

  • @paulthenotsogreat8032
    @paulthenotsogreat8032 4 года назад +1

    Those 20 dislike are from bitter professors who cannot explain this well in a 3 hour lecture

  • @hugoapresname
    @hugoapresname 8 месяцев назад +2

    Thank you for your passion, and especially for the special videos about *regulation* 😊
    That‘s why warming up when transitioning to physical (muscle cell focused metabolism) activity *makes sense* 🙏

  • @beyza4720
    @beyza4720 Год назад +6

    professor you're truly gifted with this amazing explaining ability. you make everything perfectly clear. I had listened to the recording of the lecture of my class 3 times but still had questions and you suddenly made it the easiest subject ever. don't know how to thank you enough!

    • @alitijani3398
      @alitijani3398 Год назад +1

      indeed he is. He has this incredible ability of breaking down huge stuff and explaining them in such a way that it becomes so easy

  • @chalidan.5347
    @chalidan.5347 5 лет назад +5

    You’re my life saver! These videos make biochemistry so much easier than it seems to be. I’ll surely survive from final exams because of you. Thanks a lot. You’re a genius! Greetings from Thailand :D

  • @faceyourfears7216
    @faceyourfears7216 3 года назад +5

    Had the channel recommended to me by my biochemistry professor! Amazing at what you do and I appreciate the effort put forth in helping others. Thank you!

  • @anna-mariaklaus161
    @anna-mariaklaus161 4 года назад +5

    I wish there are more teachers like you! It's seriously great job, which helps a lot. I recommended you to all my friends, greetings from Poland

  • @DARK-ej2wc
    @DARK-ej2wc 3 года назад +1

    The first time that I don’t agree with you
    How can LCFA COA as well as acetyl COA inhibit PK !!!glycolysis occurs in the cytoplasm,and beta oxidation just happens in the mitochondria 🙂💔acetyl coA and LCFA coA cant pass through the mitochondrial membrane and get into the cytosol since the presence of COA🙂💔

  • @theresahfosuah3869
    @theresahfosuah3869 7 месяцев назад +1

    Thanks for the videos. I am actually a bit confused about the insulin and the glucagon. Shouldn't rather the insulin be inhibiting the production of glucose and the glucagon vice versa ?

  • @chitrachellappa8599
    @chitrachellappa8599 Год назад +1

    Really I don't believe that I've watched a 29 min video without getting frustrated.... 😅Thank you ✨️

  • @darlenesandoval9042
    @darlenesandoval9042 2 года назад +3

    I cant believe how active i was watching this video. I watched a lecture video from my teacher that was about the same time and i swore it felt like i was watching it for hours. Watching yours to review, and it went by so fast ! Thank you! I was even laughing throughout !

  • @murtada_alsultan
    @murtada_alsultan 3 года назад +1

    Great!! That’s the limits of language to describe you , what a poor limits , Thank you from all my heart 🌺❤️

  • @timothyalston4237
    @timothyalston4237 2 месяца назад +1

    Wait he’s really good…. why am I just now finding out abt him omfg

  • @LiepLony
    @LiepLony 9 месяцев назад +1

    I do enjoy your videos Dr/professor Because you make me understand the concept with satisfactory summarization. Thank
    may God bless you.

  • @jkg6491
    @jkg6491 6 лет назад +4

    Thank you. In this video you explained glycolysis regulation really well. Kudos and keep up the great work

  • @sarahaghani7663
    @sarahaghani7663 8 месяцев назад +1

    This was an amazing lecture! I'm preparing for the MCAT and the biochemistry portion can be quite daunting. Your videos are wonderful and really help me understand what's going on instead of just memorizing. Thank you!

  • @pharmacyeducation7304
    @pharmacyeducation7304 4 года назад +1

    Nice,, boss u but speak slowly for better understing.. I am bangladesi...

  • @3500andrei
    @3500andrei 4 года назад +1

    Just a PSA: AMP is a positive allosteric effector for PFK1, not ADP according to most texts and step 1 prep books. And for the pfk2 regulation, the way you explained it is only for the liver. The cardiac isozyme is the opposite.

  • @craftfun7299
    @craftfun7299 3 года назад +4

    The way you teach is like you're telling a story and it makes everything so much easier. Can't thank you enough!

  • @karenmugo2887
    @karenmugo2887 2 года назад +1

    ❤️❤️ finally got the concept,, thanks alot God bless you

  • @saraha8472
    @saraha8472 4 года назад +1

    You will freak out if you watch this video a day before the exam

  • @asmrfantasy5642
    @asmrfantasy5642 3 месяца назад +2

    “Mmm this marker stinks” 😂

  • @naomimirauta3732
    @naomimirauta3732 5 лет назад +2

    I have so much respect for your work and your dedication! And yes, your videos are a total lifesaver. I couldn’t do anything in biochemistry if it wasn’t for your videos. keep up the good work! God bless from ROMANIA
    ^^Maybe you can make some videos on Genetics and Microbiology.

  • @AidaMessas-d9c
    @AidaMessas-d9c 9 месяцев назад +1

    From the bottom of my heart .. THANKYOU ❤

  • @Leo-ng6bo
    @Leo-ng6bo 6 лет назад +3

    Goddamn dude!My teacher should have seen your videos before ruining our lives with his classes. Thanks a bunch.

  • @sid260509
    @sid260509 5 лет назад +1

    Your videos are amazing bro.....it's a life saver for doctors who are always confused in biochem. Just one request, try providing snapshots of your whole white board explanation in the end if possible. That will be of great help for anybody following your videos and just need a quick revise of your ideas.

  • @shreyareddy3946
    @shreyareddy3946 4 года назад +2

    Sir literally U r amazing . I have never seen such cute lectures in my life I am happy I found u in RUclips but it's too late it's ok np plz sir keep doing and u r such a great inspiration...... Super cool sir😎

  • @obabiakinyele1322
    @obabiakinyele1322 Год назад +2

    Mmmm this marker stinks 😂 2:56

  • @aadyajha6751
    @aadyajha6751 2 года назад +1

    Thnkuuu so much ❤️@Ninja nerd 🥰🥰

  • @vartikasingh125
    @vartikasingh125 2 года назад +1

    Watched alot of vids but yours is the best👍🏻🙌

  • @ananyapanigrahi5067
    @ananyapanigrahi5067 6 лет назад +6

    I give you 5/5 rating.

  • @troywilliams8811
    @troywilliams8811 5 лет назад +4

    26:50
    HEY BUDDY, get ready haha

  • @jobrown8146
    @jobrown8146 Год назад +1

    Wow, our bodies are so intricate. Thank you. I wish anyone who is being tested on this type of thing all the best. I'm learning because I'm interested so there is no pressure on me.

  • @wisatshoganetso415
    @wisatshoganetso415 6 лет назад +6

    You saved my life :)

  • @sumitgami6349
    @sumitgami6349 4 года назад +1

    It's because of you, to make it easy to understand

  • @narf-rule1
    @narf-rule1 Год назад +1

    My reaction after watching his videos 21:05

  • @maesimborio7072
    @maesimborio7072 5 лет назад +1

    This is SO AMAZINGLY HELPFUL especially for students that are not fond of biochemistry,...hahah..
    Thank you so much Dr. Murphy! ^_^
    I hope to see more of your videos here.

  • @almightyelement3484
    @almightyelement3484 Год назад +2

    I just wanted to tell you how much I appreciate your videos. Yesterday I felt a little bit down after underperforming on an Enzymology exam and I was demotivated to study the overwhelming amount of information for Metabolism. I couldn't see the light at the end of the tunnel, until I remembered your channel. I started watching all your video's and everything suddenly clicked and became clear, because I'm a visual learner. I went from being totally unmotivated to enjoying studying Metabolism. And I know I'm not the only one, you keep on helping tons of students around the world, thanks for that!

    • @jobrown8146
      @jobrown8146 Год назад +1

      I would like to wish you all the best. I'm learning for my own interest and I would hate to be tested on this type of thing. It's great that videos like this are available to help both the serious student and the casual learners.

  • @eczsvl
    @eczsvl 2 года назад +1

    just 1, one, uno, ein or bir like is NOT ENOUGH for you! I just want to click like button like 1million time.... you are great! You put things together just the way I love. You are really the guy whom I have been looking for my entire learning life.... one video is equal to several weeks... all best wishes for you!

  • @sabinabaladzhaeva6774
    @sabinabaladzhaeva6774 4 года назад +1

    I am literally binge-watching your videos for the past several days! your channel is better than netflix

  • @ramissam
    @ramissam 4 года назад +1

    فاجر نيييييك ❤️

  • @raghad123456
    @raghad123456 Год назад +1

    Youre literally saving my life its not funny

  • @mariamabomousa1896
    @mariamabomousa1896 3 года назад +1

    Thank youuu, I’m constantly telling my friends to watch you.. I’m an Egyptian medical student and whenever my non-arabic speaker friends struggle in biochemistry, embryology... I tell them about you!! Keep going

  • @kinjalsolanki14
    @kinjalsolanki14 Год назад +1

    You're a gem ❤
    Thank youuu so so much for the amazing videos, I've fallen in love with the way you teach, you make understanding easier and it helps SO much, you're wonderful

  • @MugobaIbrahim
    @MugobaIbrahim Год назад +2

    your the best at this. much thanks

  • @carsonparent2885
    @carsonparent2885 2 года назад +1

    Such an amazing teacher! I never comment on videos (even the ones I like) but I had to with Ninja Nerd, this guy is just incredible. Thank you so much for the content, it goes such a long way in helping people and empowering them through their education - YOU DA MAN!!

  • @usmankharbe8772
    @usmankharbe8772 4 года назад +1

    Classy as Always Sir....
    I want to become a doctor, like you...
    Who understands each and everything happening in the body... Thank you for ur efforts !

  • @saragholami1291
    @saragholami1291 2 года назад +1

    You did manage to simplify the regulation of glycolysis.It was literally amazing .thank you very much.

  • @mikfamevlogs8278
    @mikfamevlogs8278 3 года назад +1

    Thank you so much for your videos! I’m going to take the Physician Licensure Examination on March 2021 and your videos would really aid me in passing the boards!

  • @vitushka01
    @vitushka01 5 лет назад +1

    Thank you! I never really understood this topic until this video! :)

  • @kristinas4387
    @kristinas4387 4 года назад +1

    I'm in love with you're videos 😍😍😍

  • @lightningboy9757
    @lightningboy9757 3 года назад +1

    i just cant find the propriate words of gratitude for you guys, a ninja nerd from sudan appreciating your significant and amazing hard work, may god please you and make your dreams and goals come true, i don't usually comment but i could not hold my self back on this one.

  • @jgca363
    @jgca363 4 года назад +1

    Thank you so much, sir! Please keep on doing what you’re doing. You are making our lives easier with your talent in teaching.

  • @teresalizbon7308
    @teresalizbon7308 2 года назад +1

    You are a legend. It is unbelievable how you make easy to understand such a hard subject.

  • @vermillion2580
    @vermillion2580 4 года назад +1

    These videos are pure gold!! I am actually preparing for entering veterinary medicine, so all this is way more detailed than what I need to know for the exam, but the way you explain it so logically helps me to learn faster, rather than just memorizing sentences like "glucose is transformed into 2 molecules of pyruvate, that are going to be transformed in acetyl CoA and from there results 2 ATP molecules". Somehow, having the details explained well, helps actually remember the essence. Your channel is brilliant!!

  • @جوهرةرقيق
    @جوهرةرقيق Год назад

    thank you so match الله يجازك ساعدتني كثيرا افضل بروفيسور على يوتيوب اتمنى لك كل النجاح

  • @harineepriya
    @harineepriya 2 года назад +1

    Thank you so much for the amazing teaching🙏 Keep up the awesome work.

  • @hridayeevaidya7379
    @hridayeevaidya7379 6 лет назад +1

    Your teaching skills are amazing Mam!!!! Keep it up &keep making more videos they are very helpful 😊😊

  • @Anthony-qp5hb
    @Anthony-qp5hb Год назад +1

    Each episode takes me a day or two to really sit and think about, but i'm really learning more than even my college course biology. Truly understanding, not just memorizing.

  • @thesouloflife96
    @thesouloflife96 4 года назад +1

    Amazing! I'm actually understanding metabolism from your clips. You make it seem so easy and fun😊.. Thank you 🙏😇

  • @ayaacademy7657
    @ayaacademy7657 3 года назад

    Oh my God... How can I thank you...
    You are a living talent ❤️ that just made me love biochemistry even though it's complicated..

  • @rijokripto3633
    @rijokripto3633 2 года назад

    I failed to see why PYRUVATE to LACID acids happens? Why... i assume its to PRODUCE ATP.. right? where is ATP production in that process...

  • @quantumcrash7266
    @quantumcrash7266 5 лет назад +2

    Your teachings have seeped deeply into the roots of my tree of mind.

  • @sarafecih6313
    @sarafecih6313 3 года назад

    DO YOUUUU KNOOOOW WHO YOU AREEEE ... YOU ARE THE WORD WOWWWW IF IT WAS A PERSON .... thank youuuu reallyyyyy thanks ur videos are lifesavers