I don't normally comment on videos but its such a shame that you don't have more viewers, your videos are amazing, very clear and throughout. you deserve so much more. Thank you so very much and keep up the good work!
the sad thing is that andrey kopot dosent earn from youtube no monetisation is activated by this man ,this is the reason i feel bad for this legend or its just that money dosent matter , perfection do.. thanks andrey sir love from india
its not sad cuz all he wanted to do was reacive love and provide free education, his goals acieved and is already financially stable with his doctrate profession, adds would ultimately make it more comercial
You truly are the best. You're really helping me visualize everything. A lot of professors just want to sound like a boring text book, however you really explain it so well.
OMG! i dont know what to say! that was totally perfect! thanks alot doctor..that's why i wanna travel abroad to complete my studies there where doctors like you teach us !
7:48 Most videos I've seen don't really describe how this "pushing process" happens so it's nice to see that someone is willing to explain it quite thoroughly.
Thanks God for creating languages to gather people together. Ana thanks God again that I could find you . My heart is beating when I watch your teaching
Andrey, you are my inspiration when times are tough. I have survived undergrad with you and am happy to say will be surviving my first year of med school with you! Thank you so much for your service to science!
damn.....I was in need of that style from a very long time....Thank God I found you......M from pakistan doing fsc from federal board....and it seems as u are teaching my books.....Thanku Thanku
Just one minor correction. In the video you had mentioned that the endoderm is derived from the hypoblast. Per the book "The Developing Human" on Clinical Key, it states that the hypoblast only gives rise to the extra-embryonic mesoderm (in the second week). All 3 of the layers (ecto/meso/endo-derms) are derived from the epiblast cells differentiating as such. Good lecture though, just trying to keep the more medically oriented folks on track. Cheers.
That doesn't make him wrong. I've read what he's saying from many different sources. Many different texts say the same things in different ways and may not always include all details
Amazing video! But I'd like to suggest a correction: To my knowledge, the trophoblasts differentiate into cytotrophoblasts and syncytiotrophoblasts while the embryoblasts differentiate into epiblasts and hypoblasts So in short: The structure of the blastocyst: 1. Outer cells: trophoblasts. 2. Inner cells: embryoblasts. Trophoblast mediates the implantation, and will develop into placenta. Embryoblast gives the body of the embryo
Very good video! But I learned two things different: 1. The Epiblast forms all three germ-layers 2. The extraembrionic Mesoderm that goes around the chorionic cavity is formed by the Hypoblast in an earlier stage
Thank you very much, the diagrams very super helpful! I never quite understood how invagination worked until now, this was way clearer than any video explaining gastrulation.
ive been a continous viewer of ur videos and trust me they have been teaching and enlighting me way better than books ur sooo damn god and i owe u alot cuz ur helping me become a doctor.thnx for helping me realising my dream may god bless ya n loads of success to u
Ive read in some texts that its the differentiation of the epiblast cells that give rise to the 3 germ layers, and that the hypoblast is primarily responsible for creating a lining that forms the yolk sac, but in the video you mention that the hypoblast gives rise to the endoderm as well. Is there any to help clarify this for me a little? It also states that the endodermal cells from the epiblast essentially replace some of the cells in the hypoblast layer.
Epiblast diffrentiate into intraembryonic endoderm mesoderm ectoderm, these make up diff organs in our body. Meanwhile hypoblast cell layer is pushed away, replaced by incoming proliferating endorderm layer. Hypoblast will however proliferate into extraembryonic mesoderm and endoderm. These make up chorion amnion etc
ohhhh my goshhh! im currently studying for the mcat and i literally watched 3 full videos on gastrulation and each video confused me more, your video was my 4th and i understood every single thing so easily! you are amazingggg thank you!!
i feel like this needs to be clarified : during invagination the primitive streak is formed and then the primitive node. during this time the epiblast cells migrate cranially(towards head) and as this occurs the epiblast cells detach from the epiblast layer slip under it and into the interior of the embryo. from this point the first of these cells to invaginate invade the hypoblast layer and displace that layer of cells on top with the definitve ectoderm cell layer forming the ectoderm , the cells that remain inbetween become the mesoderm and the remainder of the epiblast cells become the endoderm. so technically the hypoblast does not become the ectoderm. hope this helps
Sir, Thank you very much. i dont know why your videos have less viewer. I am your fan Sir........ thank you for making our studies simple and easy .....
Could someone kindly tell me what is meant by 'excretory system'? I'm confused as to how the mesoderm gives rise to the excretory system.. The bladder, urethra, GI tract and exocrine glands all come from the endoderm, right? So what excretory system is being derived from the mesoderm? When they say 'excretory system' do they simply mean the kidneys and that's all they are referring to?
This was a bit confusing because it looks like the epiblasts also form the extraembryonic mesoderm, but it's actually limited to the intraembryonic mesoderm while the hypoblasts already formed the extraembryonic mesoderm before the primitive streak develops.
You're videos are amazing. You do such a fabulous job making these concepts simple and clear. I really enjoy the way you concisely explain everything in such a pleasant way! (Also like your slight accent...where are you from? I can't figure it out). Thanks a million!
The first germ layer to form is the endoderm, but it's formed from the epiblast by migration from the primitive streak towards the hypoblast; only afterwards the mesoderm. Hypoblast only gives rise to extraembryonic endoderm
But i think diagrams 1&2 should be on cleaveage when morulla actually build up a tropoblast and morulla brought them tobe 32-cells which knows as blastokist and then where diagrams 1 exist they build up inner cellmass and outercell mass (tropoblast) that devided into 2 sitotropoblast(made up placenta) and sinsitiotropoblast(invasion to endometrium) when blastokist could reach deep of endometrium inner cell mass build up into epiblast and hipoblast, the next step is actually gaatrulation (week3)
I wish if my Doctors make the information as simple as you do 😢💔they take +50min just to say the same thing Keep up the good work 💪🏻📔 Best wishes from Saudi Arabia 🇸🇦 ✨
Just so all of you know, what he says is not the same of what i read in my books. I do not say he is wrong, but it is wise to be critical to theese kinds of videos. Otherwise, have a great day
You explained in 11 minutes what my Professor failed to explain in a 2 hour lecture! Thank you so much! Kudos to you!
I don't normally comment on videos but its such a shame that you don't have more viewers, your videos are amazing, very clear and throughout. you deserve so much more. Thank you so very much and keep up the good work!
For sure
the sad thing is that andrey kopot dosent earn from youtube no monetisation is activated by this man ,this is the reason i feel bad for this legend or its just that money dosent matter , perfection do.. thanks andrey sir love from india
its not sad cuz all he wanted to do was reacive love and provide free education, his goals acieved and is already financially stable with his doctrate profession, adds would ultimately make it more comercial
From undergraduate through medical school, you are my savior
finally, a video that explains this thoroughly. your a med school saviour sir
We know teachers like you are less appreciated but y'all deserve everything good in this world :)
You truly are the best. You're really helping me visualize everything. A lot of professors just want to sound like a boring text book, however you really explain it so well.
Dude, you're just brilliant! I can't thank you enough. You save me each and every time exams come up!
this is exceptional material and if not the best video to actually understand gastrulation
I'm a french student and I thank you for all these videos very simple to understand ! Keep going !
OMG! i dont know what to say! that was totally perfect! thanks alot doctor..that's why i wanna travel abroad to complete my studies there where doctors like you teach us !
Why can't my teachers in med school be like you?
I know right!
Dude, I'm in highschool and they are making us learn these!!! It's torture to us.
If you are in high school then your in the wrong section. You are torturing yourself.
huh
Ege Çakıcı me too!!
7:48 Most videos I've seen don't really describe how this "pushing process" happens so it's nice to see that someone is willing to explain it quite thoroughly.
Thanks God for creating languages to gather people together. Ana thanks God again that I could find you . My heart is beating when I watch your teaching
Andrey, you are my inspiration when times are tough. I have survived undergrad with you and am happy to say will be surviving my first year of med school with you! Thank you so much for your service to science!
actually i think that only epiblast cells give rise to all the three layers including endoderm
yes, you are absolutley right. hypoblast forms extra embryonal tissue.
that's what i thought too . epiblast is the origin of the other two layers ,that's what our teacher sad .
But hypoblast forms the endoderm...
@@junakikashyap2543 Incorrect! The Hypoblast creates the yolk sac
, as the folks above said, extra-embryonal tissue
But mesodermal cell arises from hypoblast and ectoderm formation also
Proud you are da best lecturer i have ever seen
damn.....I was in need of that style from a very long time....Thank God I found you......M from pakistan doing fsc from federal board....and it seems as u are teaching my books.....Thanku Thanku
Thank you dear, may Allah grant you all the best; you really helped me to understand this complicated process.
Zabihullah from Afghanistan.
Just one minor correction. In the video you had mentioned that the endoderm is derived from the hypoblast.
Per the book "The Developing Human" on Clinical Key, it states that the hypoblast only gives rise to the extra-embryonic mesoderm (in the second week). All 3 of the layers (ecto/meso/endo-derms) are derived from the epiblast cells differentiating as such.
Good lecture though, just trying to keep the more medically oriented folks on track. Cheers.
That doesn't make him wrong. I've read what he's saying from many different sources. Many different texts say the same things in different ways and may not always include all details
No hypoblast makes endoderm as written in many books
your explanation and drawings are WONDERFUL! Thank you for your time and effort!
oh i just want to thank this teacher too much cause i never understand this before. Your teaching is amazing.
Amazing video! But I'd like to suggest a correction:
To my knowledge, the trophoblasts differentiate into cytotrophoblasts and syncytiotrophoblasts while the embryoblasts differentiate into epiblasts and hypoblasts
So in short:
The structure of the blastocyst:
1. Outer cells: trophoblasts.
2. Inner cells: embryoblasts.
Trophoblast mediates the implantation, and will develop into placenta.
Embryoblast gives the body of the embryo
Very good video!
But I learned two things different:
1. The Epiblast forms all three germ-layers
2. The extraembrionic Mesoderm that goes around the chorionic cavity is formed by the Hypoblast in an earlier stage
That is incorrect. The Hypoblast in the Pre-embryonic stage forms the Extraembryonic Endoderm also known as Heuser's Membrane.
Epiblast gives rise to all 3 germ layers
there are two different views for formation of three layers and both the views are accepted worldwide
Thank you very much, the diagrams very super helpful! I never quite understood how invagination worked until now, this was way clearer than any video explaining gastrulation.
Just dropping this for my fellow mcat friends:
Mesoderm = move-o-derm
Ectoderm = attract-o-derm
Endoderm = inner layer = internal organs.
Thumbs up your brief and straight forward. I pray my lecturer be like you.
This video has explained almost everything that was covered in my whole-week lecture. Thank you!!!
This is a life saver during SWOTVAC, thankyou!
Thank you! This series of embryology actually help me a lot!
ive been a continous viewer of ur videos and trust me they have been teaching and enlighting me way better than books ur sooo damn god and i owe u alot cuz ur helping me become a doctor.thnx for helping me realising my dream may god bless ya n loads of success to u
ANGELOFDEATHAGK GUPTA Are tou from India?
Wow!! This lecture real help me understand gastrulation better. All the stars sir💯
Ive read in some texts that its the differentiation of the epiblast cells that give rise to the 3 germ layers, and that the hypoblast is primarily responsible for creating a lining that forms the yolk sac, but in the video you mention that the hypoblast gives rise to the endoderm as well. Is there any to help clarify this for me a little? It also states that the endodermal cells from the epiblast essentially replace some of the cells in the hypoblast layer.
Epiblast diffrentiate into intraembryonic endoderm mesoderm ectoderm, these make up diff organs in our body.
Meanwhile hypoblast cell layer is pushed away, replaced by incoming proliferating endorderm layer.
Hypoblast will however proliferate into extraembryonic mesoderm and endoderm. These make up chorion amnion etc
I watched this while preparing for my UE,it helped me a lot,I understood a lot just within 11minutes...Thanks so much brother
ohhhh my goshhh! im currently studying for the mcat and i literally watched 3 full videos on gastrulation and each video confused me more, your video was my 4th and i understood every single thing so easily! you are amazingggg thank you!!
Thank you so much! Now it is clear for me and I think everybody who has watched your video. Thanks again!
Never have i ever understood something so clearly! You're truly talented, thank you so much :D
The best video out there describing gastrulation and the germ levels. Super helpful for studying.
Betsy M thats awesome to hear Betsy! thanks!
I agree with Betsy M. :)
Lav Karri Thank you Lav! :)
keep doing this great work ,it`s really helping my younger brother,GOD BLESS u
Haris Manan thank you! will do :)
Omg you've taught me more in 11mins than 3hours at college. Thank you so much
lol oh college.. glad to hear it helped ! :)
You have a very professional skills in teaching , thanks a lot this help me a lot
way of teaching and the process of explaination is awsome....
thankyou , this explanation is so clear rather than what was given in my textbook.
Loved this video..... In fact made me love the process of gastrulation
i feel like this needs to be clarified : during invagination the primitive streak is formed and then the primitive node. during this time the epiblast cells migrate cranially(towards head) and as this occurs the epiblast cells detach from the epiblast layer slip under it and into the interior of the embryo. from this point the first of these cells to invaginate invade the hypoblast layer and displace that layer of cells on top with the definitve ectoderm cell layer forming the ectoderm , the cells that remain inbetween become the mesoderm and the remainder of the epiblast cells become the endoderm. so technically the hypoblast does not become the ectoderm. hope this helps
Sir, Thank you very much. i dont know why your videos have less viewer. I am your fan Sir........ thank you for making our studies simple and easy .....
That was a really good video and helped me not only learn but UNDERSTAND gastrulation a whole lot more. :) Cheers AK Lecturer!
Wonderful! I finally got it, thanks to you! You're so god as a teacher thanks
I appreciate your clarity so much.
Another ‘simple’ explanation. Thank you!
These videos are unbelievable.
7:48 the best part. This was all I wanted.
The Hypoblast does not form any of the 3 germ layers!! But it does induce important processes for the gastrulation and is still necessary.
Could someone kindly tell me what is meant by 'excretory system'? I'm confused as to how the mesoderm gives rise to the excretory system.. The bladder, urethra, GI tract and exocrine glands all come from the endoderm, right? So what excretory system is being derived from the mesoderm? When they say 'excretory system' do they simply mean the kidneys and that's all they are referring to?
Your videos are really amazing and encourages me to love biological science. Keep up the good work sir
You are amazing! Thank you
Maryam Hadi Thank you!
finally, it makes sense. Thank You.
thank you for the wonderful lecture. it has really helped me
The hypoblast cells don't give rise to the endoderm. The epiblast gives rise to the three layers displacing the hypoblast
OMG it’s smth unreal!!! You are the best teacher. Thank You soooooo much
well explained...very helpful to undrstnd the concept..thnx 4 uploading....
Wonderfully explained. Great fan....!!!
you are such a great teacher, Godbless you
This was a bit confusing because it looks like the epiblasts also form the extraembryonic mesoderm, but it's actually limited to the intraembryonic mesoderm while the hypoblasts already formed the extraembryonic mesoderm before the primitive streak develops.
You're videos are amazing. You do such a fabulous job making these concepts simple and clear. I really enjoy the way you concisely explain everything in such a pleasant way! (Also like your slight accent...where are you from? I can't figure it out). Thanks a million!
an amazing summary of gastrulation , Thanks a lot
this was really helpful in clearing my doubts which te books coudnt solve......thank u soo much u r the best.....
Authentic lecture👌👌👌
I'd like it again if I could.
thank you thank you thank you please dont stop teaching us !
Thank you! This is really good!
You're a great teacher, even I'm speak spanish, I understood very well. Thank you :)
The first germ layer to form is the endoderm, but it's formed from the epiblast by migration from the primitive streak towards the hypoblast; only afterwards the mesoderm. Hypoblast only gives rise to extraembryonic endoderm
suberb sir ...u explained it way to clear....👍👍👍 dont know why our college teachers dont hv such traits of lectures..very welll sir👍
god bless you, you are changing my life
Im so in love with this guy
OH MY GOD! I just think about gastrulation 24 hours and can’t find out the way until i saw this.... thank you god bless u are blessing me:))
But i think diagrams 1&2 should be on cleaveage when morulla actually build up a tropoblast and morulla brought them tobe 32-cells which knows as blastokist and then where diagrams 1 exist they build up inner cellmass and outercell mass (tropoblast) that devided into 2 sitotropoblast(made up placenta) and sinsitiotropoblast(invasion to endometrium) when blastokist could reach deep of endometrium inner cell mass build up into epiblast and hipoblast, the next step is actually gaatrulation (week3)
I wish if my Doctors make the information as simple as you do
😢💔they take +50min just to say the same thing
Keep up the good work 💪🏻📔
Best wishes from Saudi Arabia 🇸🇦 ✨
Thank u sir ...I clear most of my doubts by watching ur videos ....A huge respect to u sir .☺☺☺
You are a soul saver.
Thank you. Such a clear communicator.
5:38 correction, all 3 germ layers ( intraembryonic Endo Meso Ectoderm ) are derived from epiblast cell layer. None from hypoblast cells.
Большое спасибо парень.Если бы ты вел лекции в моем универе гистология стала бы моим любимым предметом.
you just saved my semester
Splendid! Splendid!
Greetings from the Netherlands,
Frank
Sir, you are AMAZING ! Massive respect
Yassine Mezzat Thanks! :)
Thank you for your wonderful videos. I will use these in my embryology class. :)
Thank you so much sir. Your information is very helpful 😇
Good job!! Explanation was awesome!
this is amazing! I have some questions though... but it's perfect.
As always, amazing lecturer.
Amazing lectures you provide thank you so much. May God bless you 😊😊😊
This is so so so interesting. Thank you so much
Just so all of you know, what he says is not the same of what i read in my books. I do not say he is wrong, but it is wise to be critical to theese kinds of videos. Otherwise, have a great day
thank you so much...I was preparing lecture...this video help me lot...
Your video is extremely helpful! I'm so appreciated about that, because I already search for a lot of videos but still can't understand. Thank you~
i really like your videos
me too
You rock ! Always so clear and schematic, thank you very much
your videos are a great help for me... thank you!!!!
xiao yu you're welcome :)
So good!! You are saving my life!! Can't thank you enough:)
The best lecture. Thank you so much sir.