Nattokinase and blood pressure - Video abstract [99553]
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- Опубликовано: 26 авг 2024
- Video abstract of clinical trial report “Consumption of nattokinase is associated with reduced blood pressure and von Willebrand factor, a cardiovascular risk marker: results from a randomized, double-blind, placebo-controlled, multicenter North American clinical trial” published in the open access journal Integrated Blood Pressure Control by authors Jensen et al.
Full article : www.dovepress....
Objective: The objective of this study is to evaluate the effects of consumption of nattokinase on hypertension in a North American hypertensive population with associated genetic, dietary, and lifestyle factors. This is in extension of, and contrast to, previous studies on Asian populations.
Materials and methods: A randomized, double-blind, placebo-controlled, parallel-arm clinical study was performed to evaluate nattokinase, a fermented soy extract nattō from which vitamin K2 has been removed. Based on the results from previous studies on Asian populations, 79 subjects were enrolled upon screening for elevated blood pressure who consumed placebo or 100 mg nattokinase/d for the 8-week study duration. Blood collections were performed at baseline and 8 weeks for testing plasma renin activity, von Willebrand factor, and platelet factor-4. Seventy-four people completed the study with good compliance.
Results: Consumption of nattokinase was associated with a reduction in both systolic and diastolic BP. The reduction in systolic BP was seen for both sexes but was more robust in males consuming nattokinase. The average reduction in diastolic BP in the nattokinase group from 87 mmHg to 84 mmHg was statistically significant when compared to that in the group consuming placebo, where the average diastolic BP remained constant at 87 mmHg, and reached a high level of significance for males consuming nattokinase, where the average diastolic BP dropped from 86 mmHg to 81 mmHg. A decrease in vWF was seen in the female population consuming nattokinase. In the subpopulation with low plasma renin activity levels at baseline, an increase was seen for 66% of the people after 8-week consumption of nattokinase, in contrast to only 8% in the placebo group.
Conclusion: The data suggest that nattokinase consumption in a North American population is associated with beneficial changes to BP in a hypertensive population, indicating sex-specific mechanisms of action of nattokinase’s effect on vWF and hypertension.
Keywords: subtilisin NAT, systolic blood pressure, diastolic blood pressure, von Willebrand factor, plasma renin activity
![Serrapeptase vs Nattokinase [Benefits, Side Effects, Does it Work?]](http://i.ytimg.com/vi/VngFsuyu8us/mqdefault.jpg)
![Serrapeptase vs Nattokinase [Benefits, Side Effects, Does it Work?]](/img/tr.png)
This was my experience. I used to briskly walk a 3-mile course.
My hands would swell and turn reddish by the time I finished the walk.
I started taking the prescribed normal dosage of nattokinase.
Within one or two days, the swelling disappeared and NEVER returned.
Are you able to suggest a source? My wife is Japanese... neither of us can tolerate the smell/taste of natto. thanks!
@@dieselboats7886You can easily order natto kinase capsules cheaply of many brands on the internet. Amazon is handy.
However fresh natto is also very high in vitamin K2 mk7 and probiotic Baccillus Subtillus.
I would advice to take 400 mcg K2 daily as well plus 5000 IU D3. And 300 mg Magnesium.
I love natto and have a big tablespoon daily which provides me with plenty of K2, natto kinase, and baccillus subtlis.
The B. Subtilis make it slimy, this slime protects the lining of the intestines which reduces any inflamation there of. This improves overall immunity.
I'm willing to bet, this way one can be perfectly protected against C***d. Better than any vaccine. The vitamin D blood level must be high, that is crucial. K2 and Mg make the D3 function optimally. 60mg daily of Zink is recommended too.
Just a tip.
Btw natto kinase has been shown to break down c*v** spike protein by a Japanese study.
@@dieselboats7886Wow, my comment was not placed when writing out the name of the disease that they force everyone to take harmful vaccines against.
Brave new world indeed.
@@DutchmanAmsterdam I know.... censorship at its finest, right? Brave, new world... and I'm shuddering.
Have you tried SHIATSU? Shiatsu -Massage. It can help your edema, and balance the whole body.
Sounds like your metal element is too much and your spleen.
Avoid sugar NO ice 🧊 in drinks avoid ice cream and have more warming PHO soups.
i have been eating as a carnivore for 1 year eating grass-fed beef and farm eggs, my blood pressure is 100/66. i am 66 years old and take no meds or supplements.
You're an inspiration.
Are you me??
@@danpatterson6937 what you mean?
We have a very similar statistical profile.
@@DS-nv8bi
Perhaps you are the exception DS. All the research points the cardio vascular disease in long term animal product consumption.
I'm 67 and I'm taking Nattokinase/12,000 fu and Serrapeptase/120,000 su and my blood pressure is all over the place anywhere from 191/102 down to 97/7l so I added 40mg propranolol and it is leveling off at around 145/90. I'm taking it to dissolve blood clots and relieve Sciatica pain of which is working for both in under 21 days. My mini vision strokes have stopped and I just had my first pain free day in 20 years. I will work on my blood pressure at a later date.
Can you describe your vision strokes? I might have a few of these.
@@abyssmanur3965 It started off with the bottom half would go black for 2 or 3 minutes. Then after a few months the top half would go dark for 2 to 3 minutes. I was constantly after the doctor to send me to the specialist. I don't know why he hasn't set up an appointment? Well now the vision totally goes dark for a few minutes. I'm at the point where I think I'm going to go to the specialist myself as I seen him years ago so I will still be on file there. I quit taking Apixaban and Ramipril and went on Nattokinase/12,000 fu. and Serrapeptase/120,000 su and haven't had any major symptoms since. I still once in a while I get some ghosting of darkness but it clears up before the vision drops out. I have only been on the Natto and Serra for less than 2 weeks, so it's a big improvement so far. I hope this answers your questions.
I would also like to hear a description of your vision strokes. I'm on a lower dose of nattokinase but occasionally experience vision problems. Thank you.
@@johnkuncho7239 It started off 3 years ago. I would lose the bottom half of the vision in my right eye for a couple of minutes then it would return 2 or 3 times a day. That went on for about 1 year, then it started hitting the top half or the bottom at random. That's when I demanded that the doctor send me to the specialist, which took another year to see him and I'm still waiting for my next appointment in June. In the meantime, I was having full vision loss in the eye that would return. So I went on 12,000fu/ Nattokinase/ once a day and in 5 days it stopped, but it made me feel partly bussed so I reduced it to 8,000fu and now I get the feeling of it coming on but without vision loss once or twice a week. Hope this helps. PS Always take it on an empty stomach if you can. You want it to attack the fibrin in the blood, not the food.
That’s exciting news! It also may support what I personally experienced. I was diagnosed hypertension last year. Was put on Amlodipine. This helped at first but came with severe side effects, including fatigue and muscle weakness, dizziness. I lost 15 lbs using keto like diet and also took 2000 daily dose of nattokinase. Went from 135/105 to 100/75 avg. I noticed a relief in head and nasal pressure and elimination of migraines also. I do not know if my success was due to diet or the natokinase but perhaps it’s both.
I'm taking 99mg potassium citrate five times a day to reduce my blood pressure. That's self-prescribed. I'm going to try nattokinase. Supposedly it also helps destroy the spike proteins of cov-d which I've had twice.
Hilft das Kaliumcitrat?
Try Moringa seeds to reduce BP
I take 300mg potassium twice daily and also 500 mg magnesium at night for my BP. It helps. Also, nattokinase 2000 FU twice daily.
@@skyelord6229 L-Citrulline and L-Arginine can also help.
Potassium citrate in excess can cause kidney problems, Potassium CHLORIDE somewhat safer
Excellent informative video. I take Natto everyday . I am 73 my BP is 130 over 80. Perfect
What dosage do you take a day? I take 2000fu daily. Wondering if I should take more.
@@hughesfan100 u need to take at least 4000fu daily
Thank you for conducting study. I can relate to the study as my BP started to go down after taking Natto.
Perfect delivery of important information. Could not ask for more
except for the average drop in bp.
Thank you! I just started researching the benefits of natto and other fermented foods, including Brie and Gouda cheeses, which provides the body with vitamin K2 and all the great things it does for your body! Also looking at Retinol for vitamin A, working together with K2, D3! Wow, a real eye opener! No more doctor visits!
If you take retinal take it with a fatty meal for better absorption. Green leafy vegetables and all orange vegetables are high in retinal
Nature has provided safe effective natural treatments for everything! Truly amazing. Throw away big pharma poisons and get back to nature!!
I have been using it for 8 weeks and have a normal blood pressure all varicose veins gone feeling like a wild bull just ran up a near vertical hill no puffing this morning
By "using it" do you mean natto or nattokinase? How much?
Did you use natto or nattokinase and how much
Thank you kindly for caring enough to share this information.
Adding in walking will also help take any supplements and not getting off your rear end. Walking 10,000 steps a day sure will help
I my experience, I reached the
best cardio results , and blood thinning, with nattokinase, curcumin AND slow/medium bike exercise. indoor, at gym. I get out of winter fattening/weakness in less than two weeks....
This an excellent summary of a huge study. Thanks for posting.
Natto is awesome. I lost 39 lbs eating whole food plant based and incorporated several fermented foods including natto , kimchee and fermented soy and rice liquids. I eat natto with a bit of plain old yellow mustard. My bp was sky high and my bp meds caused ED.
Natto has been key to lowering my bp and losing weight without being hungry in the least. At 50 yrs old the weight just melted off.
I would highly recommend Natto beans to anyone.
I’ll never eat another hot dog nor burger nor cheese.
Can't stand the taste/smell of Natto. Neither can my wife, who is Japanese. Can you recommend a pill form?
@@dieselboats7886 Anyway Natto is expensive from the Asian shops. Just a small packet and it cost almost $5.00.
How much do u eat and how often??
@@dieselboats7886 I think nattokinase k2 is available in pill form on Amazon
@@penggoh9934 stores like H Mart , Asian groceries etc generally sell packs of 3 or 4 servings each serving being about 2 tablespoons for $4.99 / 3 pk
Thank you for the great video, I hope you don't lose your job for making this video, here in the USA one may lose their license for saying this.
Dan Arami wtf ? She wouldn’t lose her job by giving facts ... stfu
Yes, the medical mafia is a raging acholic in the US... the good old Standard of Care keeping us all sick and dead.
Amen comrade
Oh please! Stop shaking 🙈
may be its true 😮😊😢
Thank you for sharing your research findings 🙏
Making my first batch of natto right now, feeling even more assured of its great benefits
👋💚
Post a video! LOVE to see this.
You can find a video post on y tube
Excellent, more people need to know this
I believe that Lumbrokinase (Boluoke brand) and some natural anticoagulants like ginger, aspirin, turmeric, garlic, etc... is superior to the Big Pharma poisons of Warfarin and Eliquis for existing blood clot treatment, and, of course, prevention as well.
Uhm. THANKS for comments. I started natto two months ago. I have found 100 mg are too much for me. Confusion and high heart rate, stayed on 110 bpm all day long. reduced to 50 mg only nighttime.
Serrapeptasa también es muy buena .
Now a legit video, information grom the source! Goodjob;)
Thank you I hope this can save my husbands life.
I wonder whether there is any major difference in using any Nattokinase (i bought doctor's Best 2000FU) and NKS SD form of nattokinase?
I googled nattokinase and the best one was LumaNutrition. 4,000 fu per tablet. I take 2 a day. They come in a 60 tablet bottle and I get 3 bottles, 90 day supply, for $60.00.
Apparently nattokinase dissolves polyps too!
Polips what type
Thanks for answering a$$hole.
@@dainsorensen142 Who you asking ..
@@freedomrights688 you asked Funny Isay and he ignored you.
@@freedomrights688 it’s nasal polyps by the way.
Been taking this for few years now every day .packet of natto or more home made ..Now doing this 3 hour after 2oooiu D3....
I have not check my bp after taking nattokinase, what I can say is that I have noticed that my feet and hands are no longer cold.
Same
I normally have cold hands and feet but no blood pressure issue. Do you think it's beneficial for me to take nattokinase?
@@suzannepurple yes it’s a circulation issue. Good for early prevention of anything more
How is the bleeding inclination if one Nattokinase takes? Does one bleed very much what must one pay attention to? Is it surer than with chemical products? Thank you.
I take 24,000fus daily. Have been doing for 12 months with no negative effects.
Can it dislodge the clot? We also need to discuss the risks, not just benefits
It dissolves clots.
@@deliawright8626 It can also dislodge clots. If you have atherosclerosis, it is suggested you wait for calcification/hardening before you try to dissolve the plaques, or you might end up dislodging a hot plaque.
I am on BP medication, can i take nattokinase supplement while i am taking BP medication?
It might make it too low
Go for it..I have
@@davemitchell3998has it helped, have you come off the bp meds ?
I started taking Natto 12000 fu a day and my BP is never over 105/69
Prosím o nastavení českých titulků..., nerozumím Vám
I am wondering whether the sex-specific effects on vWF may be explained higher estrogen levels in females and the phytoestrogens in natto, as estrogen is associated with an increase in vWF
I wonder, if I'm already taking blood pressure meds, what taking nattokinase would do to my blood pressure. Would it go down too far?
There is another study ongoing… supposed to be completed by now but no results have been posted. Would like to know if it dissolves clots when taken orally
Right? I have been wondering why they have not published anything.
Serrapeptase dissolves clots as well as fibrin.
@@AngelofD69I wonder why 😮
I saw a completed study online claiming the nattokinase reversed plaque in Coronary artery disease patients better than statins did. Unfortunately sometimes these results are not made easily available. As for blood clots many online articles caution against its use if you have a known blood clot. Why? Because the clot can become dislodged and then get stuck somewhere else making things even worse or fatal. It does seem to be safe for prevention of clots if you don't currently have any when you start the supplement.
Nerozumím Vám
., jsem z České republiky, mohu poprosit o nastavení českých titulků?
Hi, can i take nattokinase with amlodipine? Also with statin?
Look into statin drug side effects. Not good for 🧠 health
Amlodipine can be very harmful to your kidneys and causing ankle swelling and look up Dr Sten ekberg about the dangers of statins .
Good health 👍🍺
Statins Don't work! No sugar, no carb . Simple. It's hard to do cause of addiction that the food corruption has done on purpose . Carnivore is best
@warnatunggal433....IMO I would not take statins.
I heard a Christian doctor on tv say that the brain is 75% cholesterol. When people take statins , then the get Alzheimers 😢
❤
I am 40 having some troubles last couple months .Feeling dizzy having high pressure 158/90 at night in the morning its 120/70
Also am very tired fast and Feeling pressure in my chest . I seen 3 times the Emergency and had full check up done and all was good . Was put on Rameprill 2.5 mg should I stop taking these pills while taking Nattokiase 🤔 let me know please
i mean its worth a try . im going to give it a try because my blood pressure is high also .
Have you had a cardiac calcium scan?
You should have one done, also I'm not sure if you should take it while on BP meds. And be careful stopping BP meds
Try to find a doctor that's open to alternative medicine that you can talk to.
You cannot stop taking Ramepril suddenly.....very dangerous (spikes blood pressure).....
Its food, natto, so eat some every day. The natto is not going to hurt you. Best to eat the real whole food, the fermented soy beans. It's the drugs I would worry about....not the food. Plus walking 3km or more in morning and 3km at the evening will help.
@@ebikecnx7239try alternate day fasting
Prosím české titulky...
But how much of it did they consume in your studies????
excellent!
where can i buy nattokinaseits they have in the phel.
What about if you have low blood pressure, is it safe to take Nattokinase? Thank you.
You answer yourself
@@PtSp86retard
You don’t need it
@@davemitchell3998 My sister has clogged arteries and very low bp.
amazing
the CORRECT pronunciation is NU-TTO (natto) non japanese often mispronounce it as NATO AS in N.A.T.O.
Has any study been done on aspirin vs nattokinase? I am asking because I would love to take this instead of daily aspirin. Does anyone have any knowledge they can share as far as dosing and how long to wait for the aspirin to clear the body?
Baby aspirin lowers my bp temporarily about 10-15pts systolic and 3-5pts Dyastolic
Nattokinase 2000Fu lowers my syst bp by 30+pts and Dia bp by 10-20pts
My BP has dropped from 120/80 to 100/60 taking 2000FU daily.
@@libertysong1Where do you buy baby aspirin. I can’t find it anywhere.
What are the lab stats? You did a study where are the numbers? please!
A single-dose of oral nattokinase potentiates thrombolysis and anti-coagulation profiles
Abstract
Our aim was to determine the quantitative effects of a single-dose of Nattokinase (NK) administration on coagulation/fibrinolysis parameters comprehensively in healthy male subjects. A double-blind, placebo-controlled cross-over NK intervention study was carried out in 12 healthy young males. Following the baseline blood draw, each subject was randomized to receive either a single-dose of 2,000 FU NK (NSK-SD, Japan Bio Science Laboratory Co., Ltd) or placebo with subsequent cross-over of the groups. Subjects donated blood samples at 2, 4, 6 and 8 hours following administration for analysis of coagulation/fibrinolysis parameters. [As a result, D-dimer concentrations at 6 and 8 hours and blood fibrin/fibrinogen degradation products at 4 hours after NK administration elevated significantly] (p
Can you take natto with lisprinol. I take 100mg of nattokinase daily
I'm also on 2 anti-hypertensives and have not seen any contraindications from any of the youtube MDs. Had a triple bypass last year and don't want to go into hypotension as a result.
My mom has A-fib and low blood pressure. Her doctors suggest she is at risk for blood clots. Will this help her if she has low blood pressure?
I would like to know this as well
If I had low blood pressure I would be afraid to take anything that can possibly lower it. Could be dangerous
@@BCSTSif low BP drink 6 pints of tennents lager every day and it will rocket up 😮
Serrapeptase for blood clot, research it. Natto might lower the blood pressure
@@BCSTSNATO could make her BP TOO LOW
I'm going to use this, since my BP fluctuates
please what is the safe dosage i give mom 2000fu one cap a day should i give more im afraid
U can take up to 10,000 fu a day..thats what they used in a test I read about..I am taking about 4000 fu a day along with serapeptase and lumbrokinase..they r kin to each other and have some wonder effects on the body..
@@bjbo72how much dosage serraptase and what do u feel
Do you take it with food on an empty stomach?
yes
On an empty stomach between meals
Empty stomach
I eat the whole food, natto, fermented beans, every morning after walking. On an empty stomach with one D3 pill as they work together. Wonderful stuff, you can eat as much as you want and lose weight. Best on a little bowl of riceberry rice and kimchi for flavour as it's just bland otherwise.
I take it 1st thing in the morning..I do take natto at night also..2000 fu
Why do people concetrate on "supplements" that have marginal effect insead of getting rid of sugar, carbohydrates in general, seed oils and plant toxins (such as lectins, oxalates, phytates, etc.) which are the root cause of virtually every chronic / "non-communicable" disease today?
But what if you do both supplements and rid of the root cause
@@ajharmiah2692 In many cases, supplements are harmfull (as long as you don't have a real deficiency, of course)...
There’s nothing wrong with carbohydrates
@@contagiousintelligence5007 "There’s nothing wrong with carbohydrates"
Missinformation. Dietary carbohydrates are the primary cause of every single chronic, non-communicable disease.
There is nothing good about carbohydrates!
Shaves down plaque in the vessels too.
Say what? Darn, I wish doctors would speak on a level the average person can understand.
It lowers your BP, there ya go. Use the supplement version or use Neprinol, a blend.
dr berg king of keto
Natto apparently acts as an amphetamine as well.
Can you take nattokinase if you are on a blood thinner drug?
I take it to thin my blood. I hope they respond to you because I'm not a doctor!
I took while on eliquis. Got too lightheaded on both. Eventually stopped the eliquis and did just natto . Now trying lumbrokinase.
No don’ take both
I have 81g of aspirin. No problem. It does thin blood which helps me since I have stent.
No
What is Hybetez Remedy? I have noticed many awesome things about this high blood pressure remedy.
where can avail nattokinase .
Amazon or health food store
eBay as well
Dr Jack Wolfson, Arizona, Cardiologist
Does it work for men ? …….say so .
Yes
WHY REMOVE K2 ? ? ? ? ?
NATTO IS K2
@@kathleenking47 Really?.Wow
@@kathleenking47I thought it was vit e
If you take other supps containing K2 you won't need it in your Nattokinase supps ... Too much K2 can cause side effects.
This site is very clearly suppressing information on this enzyme. If you type in the name of it and look for reviews, and try to sort by anything other than the default relevance, it shows very little results.
pubmed.ncbi.nlm.nih.gov/27785095/
you have not studied the right info then...............
oh so this was a GYNO CENTRIC focused vid ???
Not a single question in the comments has been answered. 😀 not worth trusting.
I was wondering about that. 'Bots?
I think the date on this video was 2016.....so would not expect an answer in 2022 !
I always check dates using down arrow under videos
I think they can be sued if they give advice.
BTW, it's not pronounced like "gnat-o" it's "not-toe." Take care.
drops my bp exactly 0%
You may not be taking enough or your bp cause is not related to blood clotting etc. www.ncbi.nlm.nih.gov/pmc/articles/PMC9441630/
Gitta Jenson
She is cute
🤮
@@taedarright 😋🤢
Interesting material but I doubt that most people will understand her because she talks fast in an unfamiliar accent.
Yea, no kidding. I had to rewind a few times and still didn't understand.
You can change speed of any you tube video...look for settings symbol next to the cc symbol.
There is also a write up of what she said below video...if you click the down arrow....and a link to full article!
Was pretty easy to understand for me. Is English not your first language?
If you'd rather go to hell than New York City - you're hopelessly midwestern.
If you think that sushi looks a lot like bait - you're hopelessly midwestern.
If you think that natto looks a lot like snot - you're hopelessly midwestern.
Boiled okra
I wouldn't brag about NYC
After taking two full bottles of 90 capsules, my trial says this product does absolutely nothing at all except empty my wallet of $20 per bottle. Would be nice if it actually works but it don't.
Can you please explain, how do you know that it is not working?
@@afraimgershenzon8014 well, after being diagnosed with Peripheral artery disease I started using Natto to try and help reduce the plaque in the arteries in my leg. The symptoms never improved at all during that time.
Sorry to hear that it did not help. However, you are trying to reverse a serious pathology for which the conventional medicine offers no remedy at all.
Try to support your treatment by weight control, inflamation reduction by consuming more vegetables and less soda drink.
It takes time t
@@afraimgershenzon8014 this medicine claims to remove plaque from arteries. It is possible with diet and exercise. I am proof of that today. Unfortunately Natto was zero help
Jesse💲💲💲💲💲🦋🦋🦋🦋🦋😮
I would rather drink a glass of snot than eat that crap!
You can take it in capsule form.
😂
i sure wish you had talked more normal or read slower... you lost me
Was pretty easy to understand for me. Is English not your first language?
I say we can put the doctors and medical system out of business if we continue to do what we do with our research and find natural things that don't make us have side effects like the prescription drugs keep looking at videos everybody about doctors who are finally admitting they've been so wrong for years because the medical training system lied to them
There is no what quantity is taken
Yang milih allah like 800 ya yang milih dajal abaikan saja
You're the dajal....