Hello Keily! NaNH2 is the most common base used deprotonate a terminal alkyne by far. However, I've seen Grignard reagents used to accomplish the same thing, and while I haven't seen it formally included in a textbook (usually because we teach you about these bases much later in the 2nd semester) you should also be able to deprotonate a terminal alkyne with an organolithium reagent or LDA (lithium diisopropylamide). Hope this helps!
Worth it Chad. So much helpful and Gosh, I gotta revise the acids and bases. Seems so I have a problem determining super-duper, strong bases.
Glad the videos are helpful, Geoffrey - thanks for commenting!
This helped me so much :))))))))))))))))) Thank you!
You're very welcome! Really appreciate the feedback!🙂
Your videos are really helpful ❤thanks a million 😊
You're welcome!
Are there any other bases that could deprotonate a terminal alkyne? How could we find them?
Hello Keily! NaNH2 is the most common base used deprotonate a terminal alkyne by far. However, I've seen Grignard reagents used to accomplish the same thing, and while I haven't seen it formally included in a textbook (usually because we teach you about these bases much later in the 2nd semester) you should also be able to deprotonate a terminal alkyne with an organolithium reagent or LDA (lithium diisopropylamide). Hope this helps!
What's the reason for acidity
I wonder why they call it sodium amide
First comment
First indeed you are Vishwas! Happy Studying!🙂