#48: Schizophrenia, Fiction, Brachydactyly | Robert Sapolsky Father-Offspring Interviews

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  • Опубликовано: 30 янв 2025

Комментарии • 97

  • @vicfitz82
    @vicfitz82 День назад +46

    This series is a gem.

  • @MichaelShine-z1c
    @MichaelShine-z1c 12 часов назад +5

    Mr. Sapolsky is now my mentor. He has transformed my mind through his series of podcasts.🙏🙏🙏🙏

    • @isabt4
      @isabt4 8 часов назад

      Me too! Been following him for some years now. He has helped me more than therapy 😊

  • @iopener23
    @iopener23 День назад +13

    Very interesting and entertaining channel. I have been an admirer of Robert Sapolsky since I watched his series of lectures on first year neuroscience from Stanford University. I have also read several of his books. The father daughter dynamic works well as his daughter comes across as a very pleasant person.

  • @stevelawrie9115
    @stevelawrie9115 День назад +29

    I can listen to Robert Sapolsky and be amazed at anytime.

  • @USS-SNAKE-ISLAND
    @USS-SNAKE-ISLAND День назад +12

    I am so glad to see Dr. Sapolsky sharing his views and knowledge on such a regular public basis. He is a gift to us all.

  • @isabt4
    @isabt4 6 часов назад +1

    I majored in french literature in college. One of my professors, the great dr. Stambolian (gone too young) , told us we may forget the stories, but these studies would shape our way of thinking for life. I am 61 now. He will always be in my heart. He was a privilege to have as a professor, just as you are Dr. Sapolski and offspring for educating us the way you do! Thank you for the effort you make with this channel! ❤❤❤

  • @BradleyBuiltWoodcraft
    @BradleyBuiltWoodcraft День назад +40

    Best show on RUclips! These Sapolsky folks are sharp

    • @Saritabanana
      @Saritabanana День назад +2

      Yep. They weren’t born yesterday that’s for sure

    • @stvbrsn
      @stvbrsn День назад +2

      @@Saritabananawith his hair and beard, Robert looks like he was born in ancient Mesopotamia.

    • @Saritabanana
      @Saritabanana День назад +3

      @ Rumor has it that Robert isn't a resurrected, reclining-with-grapes, Mesopotamian ladies-man like we all thought. He's actually The real deal ancient Greek God of Baboons. He just put on some clothes and came down from the clouds to bring us some joy and awe.

    • @isabt4
      @isabt4 8 часов назад +1

      @@Saritabanana love it! 😀

    • @BradleyBuiltWoodcraft
      @BradleyBuiltWoodcraft 3 часа назад +1

      @@Saritabanana hahaha

  • @andersoestrup8066
    @andersoestrup8066 День назад +15

    Thank you both so much for yet another very interesting episode. I am one of the ones diagnosed with the debilitating illness schizophrenia and I very much appreciated hearing some of your highly competent insights on the subject. I have been medicated for years and I am fortunately at a place in my life where I can live my life with some amount of quality of life and dignity. I am very privileged to having received good treatment and living in a country (denmark) where treatment and therapy, while not perfect, is still excellent compared to other countries, and also available for free. It has literally been a life saver.

    • @isabt4
      @isabt4 8 часов назад +1

      Love reading your comment. Schizophrenia sounds so incredibly challenging! Congratulations on reaching a good place in your life! ❤

    • @andersoestrup8066
      @andersoestrup8066 3 часа назад

      Thank you so much for the very kind message ❤

  • @Horibonda
    @Horibonda 23 часа назад +6

    Offspring are soooooo lucky to have this dad

  • @mijzelfmaardanik
    @mijzelfmaardanik День назад +12

    These is one of the most high quality shows on RUclips or even the Web, please never stop with These ! and thank you for all the effort you are putting in to it !

    • @isabt4
      @isabt4 8 часов назад

      Absolutely! ❤

  • @real_pattern
    @real_pattern День назад +4

    hilarious thumbnail, "one of my great grandparents was a pterodactyl" + irresistible sapolsky facial expression, what a banger

  • @naturalismundi4359
    @naturalismundi4359 День назад +8

    One of my oldest friends developed what I can non-clinically derive as a form of paranoid schizophrenia. This saddened me as she was a brilliant mind yet somehow over the years fell into her shadow; I can talk to her, yet I get the feeling that if say something wrong I will quickly be moved from helpful friend to part of a conspiracy of people out to harm her. I can watch it happen. What I have been told is that I cannot help her, yet I am also told that the drugs involved in changing her delusions are often terrible. This is (your podcast) one of the best descriptions of what goes on in her head and why. Will research this further and thank you both.

    • @naturalismundi4359
      @naturalismundi4359 День назад +2

      Addition: Reading your comment section, aside from the well deserved praise, is very interesting.

  • @MarkLamont-m2o
    @MarkLamont-m2o День назад +6

    Best youtube channel of all time :)

  • @kristine6996
    @kristine6996 День назад +8

    I love your way of making science susceptible to all of us. Merci.

  • @thomasmaddox5638
    @thomasmaddox5638 День назад +12

    Terrific. Just days ago, someone asked me about Schizophrenia. I remembered a fair amount from Prof Sapolsky's lecture. And now, this morning the question is raised... Thank you so very much. Just love you both for what you are providing... just makes me more "bonded" with neurobiology!!! Great!!

  • @zezezep
    @zezezep День назад +12

    You two improve my mood

  • @Katzenjammer70
    @Katzenjammer70 День назад +11

    I was so happy to find a new episode

  • @michaelsee6553
    @michaelsee6553 День назад +5

    Love you guys. You teach me so much, and I so often am able to relate it to my own life or to that of people around me. Thank you.

  • @minus4025
    @minus4025 15 часов назад +2

    Excellent show !

  • @jamesbishop9156
    @jamesbishop9156 День назад +9

    Thank you, I do enjoy your talks. 👍😁✌️🙌💯

  • @curiousreporter4292
    @curiousreporter4292 День назад +8

    Good morning sir Sapolsky

  • @susanjames8134
    @susanjames8134 День назад +3

    Very educational and fascinating. Thank you!

  • @mozartsbumbumsrus7750
    @mozartsbumbumsrus7750 День назад +2

    My long-time sonata partner (35 years long) had small hands. That didn't stop her from becoming one of the greatest and finest masters of the piano. London, the capital of pianists in the world. She had a finger stretch that you could put a ruler on and draw a straight line from pinky to thumb (1 to 5). She could tackle and play anything, from Rachmaninov and Liszt to Bartôk, Prokoviev, Mozart and Beethoven Brahms Bach Berg Schoenberg Ireland Horovitz Chopin Stravinsky you name it and music written for us both. She had sightreading technique ability that was performance ready at prima vista. I loved it because we had the largest repertoire of anyone in the world as I could perform the gamut! Wow! She would modify her technique when we spent time rehearsing thoroughly for a performance but the pleasure of bringing a new work to her for us to play instantly was a deeply satisfying pleasure unique and I miss her very much. So, Robert, all is possible for you, too!

  • @sallytwotrees5250
    @sallytwotrees5250 День назад +4

    Proffesor Sapolsky🙏🙏🙏🙏
    Could you please add Russian subtitles to your video's?
    It would give so many non-english speakers the opportunity to gain valuable knowledge 💕

    • @alex_bakkalinskiy
      @alex_bakkalinskiy Час назад

      Try auto-translate in RUclips? Check out the setting button! Works for me 😉

  • @XYZ56771
    @XYZ56771 День назад +3

    Great insights, thank you so much for sharing!

  • @OrafuDa
    @OrafuDa День назад +4

    12:45 To me that sounds like the default mode network is producing these thoughts / auditory hallucinations. It has the whole bandwidth of self-talk repertoire, from motivational to demeaning, and commenting on the person, their relationship with others and their position in the world, etc.

    • @alex_bakkalinskiy
      @alex_bakkalinskiy Час назад

      I too had "the demon network" term playing in my head at that moment of video 😄. But that DMN is a clunky abstraction with lots of strings attached. You have to tell background things if you mention it. So I imagined myself in Robert's place and I think I would skipped it here too, for shortness of storytelling. But demon-net is a huge topic, super interesting!

  • @KeithCooper-Albuquerque
    @KeithCooper-Albuquerque 19 часов назад

    Thanks for another wonderful episode! Y'all rock!

  • @geokoo
    @geokoo День назад +4

    Thank you for the knowledge 🙂

  • @Rigoroushonesty
    @Rigoroushonesty День назад +6

    When I hear voices, they sound like an actual audiological event. Like news casters talking at the same time coming from a TV that isn't on. Or the insults feel like it's coming from someone in the room - I'll look for who it is.

    • @austindeeter321
      @austindeeter321 День назад +3

      That’s a good way of putting it, it sounds like news casters of people I know talking coming from a TV that isn’t on.

    • @natas12rm
      @natas12rm 9 часов назад +1

      I hear News caster say crazy stuff when the tv is on, I hear people like you as well, I also hear people like they are speaking inside my head. It’s terrible. Is it real though sometimes? I’ve had people react to what I’ve heard as if they heard it.

  • @christinavannorman3259
    @christinavannorman3259 День назад +10

    I'm very interested in the aspect of voices in one's head. When I was in my 20s those voices were horrible, telling me to do horrible things, haunting me, etc... Now I am 59. Some time ago, these voices changed. I never had therapy, never took any drugs, but did to a lot of meditation, spiritual work. Now these voices are friendly. They give me good advice. They tell me to, for example, "shut up and listen to this person," or tell me , in a dangerous situation, "leave now." Have you heard of such things ? What is your take on such a change from horrible instructions to really useful advice?

    • @Tarzosaurus
      @Tarzosaurus Час назад

      I know I'm not who you were asking, but your comment reminded me of some papers I read a while ago on cross-cultural schizophrenia, just in case you hadn't looked into it already! There was a significant difference reported in American subjects versus those in Asia (India, China) with those in Asia stating the voices they heard were typically more positive, complimenting them, the voices of their elder family members instructing them on tasks, etc, whilst the American ones stated theirs were mostly negative, violent and degrading towards them. Of strangers, or less personal relationships rather than family.
      I'm not sure if its correct or not, as far as I know there's limited research in the area but enough to have shown a pattern anyway. It would certainly be interesting to hear Robert maybe expand on it!

  • @alex_bakkalinskiy
    @alex_bakkalinskiy 48 минут назад

    (1) I had like dozen millisecond dopamine spikes while listening! 😄"Pay attention", really interesting things are in the air! Schizophrenia hypothesis is elegant, predictive explanations for salient subliminal feelings. I often skip pathology parts in neuroscience articles, they sound boring and clunky. And here is a cool idea! 🤩
    (2) Fast by-passing jokes, without waiting for audience to laugh. And it sets kind of humorous mood, easy and funny. I think I “subvocally” was smiling a lot while viewing 😃. Robert was juggling so easily - one mental model after another, telling only the crucial core ideas, without swamping people with details
    (3) Two words were circling in my head, “master storyteller”. Robert sure knows how to tell things so you keep listening with your jaw dropped. Topics are not fiction, but it is harder to make a captivating strory when you do not make thing up as convenient for author, the easy hollywood-scenario-turns. That’s what shows you “master storyteller” talent. Yeah, a bit of envy here on my part 😁
    (4) That bit about “1 to 2% of population” for schizophrenia at the start. I was surprised, I googled it, I saw (veni-vidi-vici) “schizophrenia affects around 0.3-0.7% of the general population at some point in life” (in WHO and wiki). I got puzzled. My guesses are: 1. slip of tongue, 2. Robert meant non-clinical schizotypes in that value, 3. Something else
    Can you clarify? 🙏

  • @billkress2606
    @billkress2606 День назад +5

    Brachy Bill here. Thanks Robert! That was highly informative and entertaining. Guess I'm an A-1 too, then. Also not a Trump dick, haha. I'm also 67, with Dupuytren's affecting only my right pinky. Any connection to brachy mutations? Thanks for the deep dive. Keep clanging those keys :)

  • @rinaf.7876
    @rinaf.7876 6 часов назад +1

    this is the day I found out I have Brachydactyly

  • @luisladino6162
    @luisladino6162 День назад +3

    Thanks so much. ❤

  • @Alex-js5lg
    @Alex-js5lg День назад +2

    21:00 "You don't spread out everywhere." You haven't seen how I sit in a movie theatre.

  • @MilesCushion
    @MilesCushion День назад +2

    ⚡ EXCELLENT CONTENT⚡©®™

  • @GaryWornell
    @GaryWornell День назад

    Wonderful! Thank you.

  • @Natalie-td2mq
    @Natalie-td2mq День назад +6

    How do you guys not have a merch store with "what's that about .." t-shirts 😅 always love your videos /talks ...followed for years 🙂

  • @adashirmohammadi701
    @adashirmohammadi701 День назад +4

    He’s the finest specimen of Homo sapiens sapiens in existence.

  • @tracy9610
    @tracy9610 14 часов назад

    As an bridge between questions 2&3, there's a French book (”fiction”) called The Elegance of the Hedgehog. The main character gets hit by a dry cleaners delivery truck at the very end.

  • @yaongingyfmm1571
    @yaongingyfmm1571 День назад

    Episode 46 & 2! Deep cut...

  • @m.dgaius6430
    @m.dgaius6430 21 час назад

    I am personally responsible for the sales of thousands of copies of BEHAVE through recommendations. I was thinking I could get a cut. Thanks!

  • @hammersaw3135
    @hammersaw3135 День назад

    Schizophrenia hallucinations, is primarily due to fluctuations in activity in the default mode network, which is also implicated in ADHD, mood disorders, various Anxiety disorders and PTSD. Psychosis is terrifying, and can also occur as a feature of other disorders such as depression, bipolar and PTSD

  • @jamesbishop9156
    @jamesbishop9156 День назад +3

    Everyone has their own tunnel vision of reality....
    The tunnels do overlap in shared realities...

  • @jimwilliams3816
    @jimwilliams3816 День назад +4

    I would suspect that psychology does play a role in the typically horrific nature of schizophrenic voices - or for that matter, intrusive thoughts - but I’ll offer another possible mechanism: the negativity bias that Sapolsky has described as a default condition in humans, that bad things are stimulating because they may require action on our part. I submit that this can be especially true with mental health difficulties, because the brain can be acutely aware that something is very wrong. That something is the brain itself, though we typically look for external threats, hence paranoia.
    I found the alert spikes intriguing. I could imagine how slightly to very atypical functioning might create a spectrum of human experience, ranging from those who make useful intuitive leaps at its most benign, to the sometimed disorganized and distracted thinking of ADHD, to something like schizophrenia at the most damaging end. I suspect it’s often an eclectic blend of good and bad; there’s a lot of overlap between creative thinkers and mental health challenges.

    • @jimwilliams3816
      @jimwilliams3816 День назад +1

      Edited to add: I opted, for once, not to get into my own mental health issues, since I’m prone to oversharing. But since others have done so, I’ll mention that, while I do not have schizophrenia, I based my observations on my own atypical cognition and lived experience.

    • @naturalismundi4359
      @naturalismundi4359 День назад +1

      Good thinking. Of all the sciences, the science of the brain remains the most interesting and the least understood.

    • @isabt4
      @isabt4 8 часов назад

      Your thoughts sound viable to me . May all of us with mental issues find a way through them. Wishing you all the best ❤

  • @Canceledopoulos
    @Canceledopoulos 6 часов назад

    Haven’t watched this yet but I watched his lecture and what stood out was that it’s virtually impossible to go schizophrenic after 30. Does this mean that «schizophrenia» after 30 is neuralink testing?

  • @jrnmadsen2710
    @jrnmadsen2710 22 часа назад

    Good news. Recent research shows the greatest correlation between the size of the nose and the size of the "man".
    With a huge potato on my face (but small hands), I hope that the knowledge of this research spreads all over the world. :)

  • @infiniteworfare5089
    @infiniteworfare5089 День назад +2

    i always wonder whether animals and plants get mental conditions. does diversifying selection play the biggest role in selecting out these conditions?

    • @PinataOblongata
      @PinataOblongata День назад +1

      Obviously only if the selection pressure works on the traits being expressed. You might several different environments with different selections pressures, but if the genotypes giving rise to aberrant mental states don't rise to the level of something that can affect the individual enough to interact with those pressures, (e.g. there is a small amount of food and an aberrant mental state makes the individual avoid all but one type and they become malnourished) then what is selected out/in will be other traits. Traits that don't really interact with selective pressures tend towards being either maximised or selected out completely over time. That is either random or to do with how the genes that give rise to them interact with or reside along with other genes.

  • @theAmygdalaiLama
    @theAmygdalaiLama 23 часа назад

    I'll work it out elsewhere, but having one of those thoughts randomly at the same time as the dopamine heartbeat pulse or something, seems important, that Theory of Mind gets summarized into the Human Nature meme, and you have Theory of Mind if you believe all we put in that, and that's neurotype specific, Theories of Mind are likely neurotype specific, there's already a context for our theories . . . sorry, thinking out loud. Thanks. Very thought provoking episode. Stay safe.

  • @AdityaKumar-qy2su
    @AdityaKumar-qy2su 4 часа назад

    I love you, ❤ sir

  • @richardcrosswicks7058
    @richardcrosswicks7058 День назад

    Now I can't atop looking at your fingers. 'They call 'em fingers, but I never see them fing'

  • @Saritabanana
    @Saritabanana День назад +1

    I never noticed these stubby fingers. They are very cute

  • @Saltytoxico
    @Saltytoxico День назад

    Does every human have a genetic defect of some sort? What's the baseline being used?

  • @oonaghcleary3645
    @oonaghcleary3645 День назад

    Prevention is better than cure

  • @jamiegallier2106
    @jamiegallier2106 День назад

    ❤❤❤

  • @klausgartenstiel4586
    @klausgartenstiel4586 17 часов назад

    from what i've heard, trump is also a great pianist, but i've never seen him in his birthday suit.

  • @theAmygdalaiLama
    @theAmygdalaiLama День назад

    OK, now you're getting personal, I mean, I got that, type A1 - thanks for naming it for me! - I've been fixated on your hands too, because they are mine. PIANO, really? I can barely make chords on the guitar, I pare my guitar necks down to banjo size., and still struggle. Something, I may email this to you also to try to ensure you see it - I have recently learned that Mom took Thalidomide, and I have other troubles, but it is well documented that the drug shortens bones. They say the very first, smallest known symptom is short arm bones leading to shoulder dislocations. Not really asking if that's common or possible for you, more that perhaps we can conclude one area of genes that Thalidomide affects? I have kids, I'm curious if I have to worry about effects to them. They have normal fingers.

  • @patrickkish6662
    @patrickkish6662 День назад

    I have a sincere question. I have enjoyed your lectures and presentations over the years. Your daughter seems to present with what I would call, uhhh, character. You always present with.... information. Do you have a more pronounced character out of the public eye? If so, would the projection of a more complete, and genuine self to all, under any circumstances, be potentially of more benefit to society at this time than a recorded and documented non-biological body of work? This may be a totally inaccurate observation from a high school dropout. But it seems your daughter is using this platform as a means to try to cultivate and draw more of your genuine character out, and into the public eye. It's quite touching to see, actually. As I've heard about biology, true evolutionary change comes from the bottom up. It appears she's trying to evolve you. That's a good egg, Dr Sapolsky.

  • @oonaghcleary3645
    @oonaghcleary3645 День назад

    I would like to mention that Professor Luke O Neill professor of biochemistry and immunology at trinity college Dublin states in his article in his newspaper article dated 29th October 2023 called the Sunday independent newspaper that babies born to fathers over 50 have an up to fivefold risk in developing schizophrenia again older parents increase the risk of mental health conditions in their offspring not enough is spoken about these increased risks of older parents having children

  • @sarahricefox9042
    @sarahricefox9042 20 часов назад

    So fiction is pop culture and literature is elite, educated culture?

  • @Entheos84
    @Entheos84 День назад +1

    I saw this and was like: Wwwwowwwwwwww! ❤

  • @aethylwulfeiii6502
    @aethylwulfeiii6502 3 часа назад

    I think he messed up serotonin with dopamine.

  • @AbisolaDamilola5007
    @AbisolaDamilola5007 День назад

    We 😅 dope fiends. But we all deserve it 😂. Academia in America 😢. Until my mother! Clocked out 😅. And now? I’m attentive.😮😊😮😢🎉❤😂🎉😅😮😊😊.

  • @Horibonda
    @Horibonda 23 часа назад

    Just sayin’. I would never make any comparison of your hands to that orange guy….😔🇨🇦

  • @AdamShaiken
    @AdamShaiken День назад +1

    I...would prefer not to.

  • @cht2162
    @cht2162 День назад

    I favor Norma Jean. 💋

    • @tracy9610
      @tracy9610 14 часов назад

      Is that Marilyn Monroe?

  • @infinidimensionalinfinitie5021
    @infinidimensionalinfinitie5021 15 часов назад

    i don't like it;
    when i hear;
    allusions of certainty;
    as to what "science" has decided;
    especially allopathic "science"
    not heisenbergian enuf for me;
    i am all for science;
    just heisenbergian science;
    i self-identify as semi-schizophrenic;
    i hear the voices;
    i realize that the voices might be skull-implanted headphones;
    could be a quick shot, like some vaccinations;
    so you wouldn't know what happened;
    all of a sudden you're typing on and on;
    about bullshit;

  • @MTVBrat5eva
    @MTVBrat5eva День назад

    So here is where I'm at prof.. explain to me the difference between serotonin and dopamine. The two are, like, synonymous to me. Don't fatrkeep or, Gatekeep me even, gatekeepers, because here's where I'm at and, to be honest, I'd rather buy tobacco and its associated accoutrements than black spray paint and spray it in noir band on what is essentially the primordial soup of life (that being trash) because Odilon Redon already carved that route and I totally don't even wanna be that sad. PLUS, *takes deep drag and then another..band another ad infitet cetera* and I can't afford both. *Swipe board+ "whatever that means"... O, p.s I'm smoking and it's jeopardy. "What is R. Sapolsky's beard?" ... *Stumps out BUTT so as not to be blamed, read, underlined *accused* of starting a or the fire"*.. "stud".
    Ya with me, bobe?
    And therefore I am not Russian! *Checkmate*

  • @stevenlaube7535
    @stevenlaube7535 День назад

    if you do not believe in free will some do not believe in free will even if its defined as "choosing the from a set of habituated model's " , (no free will karma rubbish ) Schizophrenia can be deflective referencing to a you a target or a general attack upon a hated enemy not a third person not being personal ,,
    great job Rachel i think Bob's lost this rabbit hole ,Schizophrenia is a bit to deep for him ,,good try Bob

  • @claudiaxander
    @claudiaxander День назад +1

    Always a joy! Cheers