Shock | Clinical Presentation

[@najla1u218]

How 10 mins made me understand a whole concept 👏🏻👏🏻👏🏻

[@DrAdnan]

This video is so important for Internal Medicine rotations

[@zhiwaskalimba4096]

thank you ver much, i personally prefere fast and short explanations, and u nailed it .

[@zhiwaskalimba4096]

@@ariesjensen59 love how you guys r both the same account lol, who would see a reply of a reply in less than an hour lol

[@Bill.R.124]

AWESOME> I teach shock to my nursing students and I'm going to watch this with them (says things better than I can in many ways)

[@shubhamghodke3760]

We need more teachers like you 😭

[@hongphuongnguyen5330]

Ischemia: lack of blood flow to tissue (circulatory failure) --> lack of oxygen and nutrition --> cellular damage --> organ failure
Shock: body-scale ischemia --> multiple organ failure
Blood pressure determines perfusion of oxygen and nutrition to tissue
Blood pressure = resistance x cardiac output = resistance x (heart rate x stroke volume) = resistance x heart rate x (end diastolic volume - end systolic volume)
: low cardiac output --> low blood pressure --> low perfusion
+ Low blood flow --> low tissue's heat --> cool and clammy skin
+ Low mixed venous oxygen saturation
Regulation (goal: normal perfusion): low cardiac output --> release of catecholamines, ADH and angiotensin II --> vasoconstriction --> increases resistance and heart rate --> increase blood pressure
(low-volume-blood) SHOCK
1. Non-hemorrhagic (not-from-bleeding) --> occurs when suffering severe dehydration --> low blood volume --> low stroke volume --> ...
2. Hemorrhagic (from-bleeding): starts when loss of about 1 liter of blood (20%) --> low blood volume --> low stroke volume --> ...
(heart-produced-by) SHOCK
Trauma (usually heart attack) --> damage of heart muscle cell --> weak contraction --> low stroke volume --> ...
Obstruction in heart (fluid or blood in pericardial sac) --> constriction of heart muscle from expanding --> low stroke volume --> ...
: low resistance --> low blood pressure --> low distribution to (some) tissues
+ High blood flow --> high tissue's heat --> warm and flushed skin
+ Normal or high mixed venous oxygen saturation
SHOCK: caused by leaky blood vessels or excessive vasodilation
2 subtypes: anaphylactic shock (allergic reaction) and neurogenic shock (damage of CNS --> can't control blood pressure)
Most common: SHOCK (from pathogens in blood): endotoxins --> low perfusion
--> direct damage of endothelial cells --> release of vasodilators
--> activation of complement pathway --> activation of mast cells --> release of histamine (vasodilator)
Pathogens --> activation of macrophages and neutrophils --> release of cytokines --> release of inflammatory molecules by endothelial cells --> damage of endothelial cells (again!) --> leaky blood vessel and more blood clotting --> low perfusion (more!)
TREATMENT
Goal: stabilize blood pressure --> vital organs can be perfused with blood --> fluid replacement and medications
Often: supplemental oxygen and airway protection

[@grahammoulton3374]

This is an excellent beginner's guide to shock ! Thank you!

[@EiliyaLavasani]

You really explained the whole concept in 10 minutes, thank you very much 🔥❤

[@alexmedisolution]

Your voice is so sweet and clear

[@samrudhipratapwar1349]

Worth watching ur video

[@taniamandal5960]

You are a magician...how you clear all concepts in just 10 min😮❤

[@thin_27]

I had my 2nd presentation tomorrow so i think I kinda feel like i found a holy grimwore of shock for quick understanding 😅

[@annafelsner6632]

never seen it that well explained!

[@rebeccagonzalez2407]

Great video! Super helpful! Thank you so much!

[@erayerge5233]

ı always understand the mechansims in this channel. thanks a lot from Türkiye !

[@haridineevikhe8549]

The best video for shock ❤️❤️❤️

[@clarkienabablit4460]

They never teach me like this during my college time, i spent 48 month in college, but here just 10min i learned a lot.
My point is why should i spend my time for 4years in college if there's a way just only 24hrs i already finished my medical degree in college. It could be a lot of money that i saved in my bank account .

[@fufu6517]

Are you tripping 😂

[@sehrish_official91]

Awesome 👍

[@sragdharaghosh3582]

You are my life saver!

[@rachelwentz6253]

Excellent overview!! Thank you!

[@hikmatullahkhan2021]

Thanks sir, such a best video

[@tanzeelzainab8520]

can u.load all.osnosis video

[@azadmirza1871]

Awesome

[@dagbalakkamara800]

So helpful

[@tanmaysinha6647]

Speechless

[@Lastonbanda837]

Thank you, much appreciated

[@sumanchoudhary8263]

Thank you so much

[@bublisoniyak6227]

Thank you 🙌

[@mariamusman142]

Excellent♡

[@leilanin8020]

How is blood flow increased in distributive shock when blood pressure is decreased ?

[@aminsediqi2489]

around 7:34- 8:22 - if we have microvasculature blockage - doesn't this increase resistance and therefore make it harder for blood to move around the body? If not why? Is it because blood gets shunted away from the capillaries via collaterals? and I'm assuming this has the added benefit of bypassing tissue perfusion?

[@Dr.Nantiwa]

I was confused as well

[@naeemnawazmughal8916]

Can anyone tell from where the content is taken i mean which book

[@roroalzaben_]

OMG THANK YOU VERY MUCH 🙏🙏

[@muhammadkhaled1787]

Pretty amazing

[@muneezamemon4883]

How there is increase in blood flow during distributive shock?? As BP in increased?

[@IN-rw5bl]

Thanks

[@mehwishzulfiqar8352]

Thank you so much ❤️

[@abdulqayoom6754]

Like genuilyyyy besttttt

[@mwangigideon7136]

DAMN !!you guys are great

[@anamikamaji9519]

Thank you♡

[@_Marthinzen]

Great!

[@boranorabora4431]

Thank yooooouu❤

[@KOMALKUMARI-ep8et]

Thank u😊

[@Sandra__2q]

Don't miss the exclusive interview with Binance's CEO for a glimpse into the future

[@imaginarytechinhindi5507]

1:48 , gave Chubbyemu vibes

[@Definitely299yearsold]

Interpretion of my dad’s immune system

[@suryanshvaibhav]

Bruhh ❤

[@edlorens]

Thanks.

[@abdosayed9807]

بسم الله ماشاء الله

[@dr_sourav3691]

I want to make some videos on medical topics by collaborating with you... Will u collaborate??

[@ashi177]

Osmosis it is!

[@MsElke11]

Basically, I should be drinking more water.

[@7h268]

That's what i thought too

[@mrshagan8613]

Do uncosiosness

[@inappropriatamentechitarra]

First reaction, shock! Shock bæcaus...

[@caribaez5711]

Did you steal the video from osmosis? This video is good but I hope osmosis is nice to you. Give credit to them.

[@andrewden1699]

Literally says Osmosis at the beginning

[@muhammadsohailali5307]

Are u here to clear your concepts or to accuse him for stealing?

[@ajaj4538]

The end of the video says that others are free to share and adapt the video

[@ayushsharma8086]

👌👌👌👌🙌🙌🙌🙌

[@sudhanshuvinayak5492]

👍

[@marcosmontanez5234]

💎

[@muhammadaliaslam4023]

💜❤️

[@praise2217]

🤗👍🙏🙏

[@anuskasharma9110]

I cant understand

[@tanzeelzainab8520]

they have dleted

[@ahmedalamery729]

Arabic caption?!

[@monashon2328]

Thank you so much

[@bisanbashkami4665]

Thank you so much 💕💕