the video is already in english, you can click subtitles from your end please subscribe and share my lectures feel free to contact me on 8919754133 india on watsapp
15:30....Do we have to remove the cofactors?...If we do so..then how protein docking results would be rational?..In real environment, cofactor will impart some role in protein activity...How ca we deal with that sir?
Not all cofactors are important in docking only few it depends on the protein for example if you are dealing with ACE ZINC IS IMPORTANT other cases it might not be so careful selection is necessary
Sourabh Chavan no it’s not necessary you can dock while retaining cofactors also and even if you remove no issue .... my intentions was you should not select them as ligands
Excellent content! I have 3 ligands that i would like to test for docking to two molecules. Is this something that you would be willing to do for a fee? thanks!
Dear Sir,How can I download/get discovery studio client?. Because in my DS visualizer, all simulation and small molecules option like minimization,DFT calculation don't show.
sir, my discovery studio is not show many many things for performing like in SMALL MOLECULE category ( prepare/filter ligand, minimize ligand,calculate mole. properties,create QSAR model etc) it show few, what should i do sir, again i download it or something else?
Super sir
Please subscribe and share my lectures contact me on Watsaap 8919754133
Sir, how to perform docking using the homology modelled protein and how to select the binding site in it
dear Student see all my videos on docking u will get the answer
Please english subtitle. Thank you
Already the video in English
the video is already in english, you can click subtitles from your end please subscribe and share my lectures feel free to contact me on 8919754133 india on watsapp
My listening english is not good. Can you turn on English-auto, Sir? Love your channel very much
check now
@@Dockingbydushyanthreddy when you click CC, you see "English-auto generated". I just see "English" and the video still has no subtitle.
15:30....Do we have to remove the cofactors?...If we do so..then how protein docking results would be rational?..In real environment, cofactor will impart some role in protein activity...How ca we deal with that sir?
Not all cofactors are important in docking only few it depends on the protein for example if you are dealing with ACE ZINC IS IMPORTANT other cases it might not be so careful selection is necessary
@@Dockingbydushyanthreddy Ohkay...If they are important, then in preparation procedure, any changes are required ?..
Sourabh Chavan no it’s not necessary you can dock while retaining cofactors also and even if you remove no issue .... my intentions was you should not select them as ligands
@@Dockingbydushyanthreddy Okay ...Thank you sir
Best
Please subscribe and share my lectures
Contact me on Watsapp 8919754133
Excellent content! I have 3 ligands that i would like to test for docking to two molecules. Is this something that you would be willing to do for a fee? thanks!
Please subscribe and share my lectures with your friends and others feel free to call me on WhatsApp +91 8919754133
Dear Sir,How can I download/get discovery studio client?. Because in my DS visualizer, all simulation and small molecules option like minimization,DFT calculation don't show.
For that you need to purchase the software
You can contact me on Watsapp 91 8919754133
sir, my discovery studio is not show many many things for performing like in SMALL MOLECULE category ( prepare/filter ligand, minimize ligand,calculate mole. properties,create QSAR model etc) it show few, what should i do sir, again i download it or something else?
u are using free software hence ur limits are defined