Atrial Septal Defect (ASD) USMLE Step 1 Pathophysiology

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  • Опубликовано: 18 сен 2024
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    Atrial Septal Defect (ASD) - USMLE Step 1 CVS Physiology , Dr G Bhanu Prakash
    Atrial Septal Defect
    Overview
    ---------------
    Atrial Septal Defects (ASDs) arise from defective closure of the inter-atrial septum and allow for an inappropriate right-left shunt of blood following birth. ASDs are the most common subtype of congenital heart disease.
    Normal Development
    Overview
    The right and left atria emerge from a single chamber which is septated between the fourth and sixth weeks of development. Atrial septation develops in such a way as to allow significant shunting of blood from the emerging right atrium to the emerging left atrium, a physiological priority during fetal life. However, following birth this shunt must be rapidly ablated; consequently, the inter-atrial septum develops in such a way as to provide a "flap-like" system that can be shut quickly following delivery.
    Septum Primum Development (First Wall)
    The first septum to divide the common atrial chamber grows, ridge-like, from the superior aspect of the atrium downward and eventually fuses with the Endocardial Cushions which defines the inferior aspect of the chamber. The hole defined by the advancing edge of the Septum Primum and the Endocardial Cushions is known as the first hole (Ostium Primum). As the Septum Primum fuses to the Endocardial Cushions (Destroying the Ostium Primum), a second hole is formed in the middle of the Septum Primum, known as the Ostium Secundum (Second Hole), which continues to allow right-to-left shunting of blood.
    Septum Secundum Development (Second Wall)
    A second wall, known as the Septum Secundum, begins to develop directly to the right of the maturing Septum Primum. As the Septum Secundum develops, a hole is formed in its center known as the foramen ovale which continues to allow right-to-left shunting of blood. Because the superior aspect of the Ostium Primum eventually regresses, the Ostium Primum begins to act as a flap against the foramen ovale and in doing so allows only unidirectional movement of blood from the right to the left atrium.
    Delivery
    During fetal life the right atrial pressure is slightly higher than the left atrial pressure, allowing blood to shunt from the right to the left atrium and thus bypass the developing fetal lung. Following delivery, the atrial pressures switch, causing the flap-like Ostium Primum to shut the foramen ovale, limit shunting of blood between the two atria, and thus promoting blood to enter the now mature fetal lungs.
    #atrialseptaldefect #usmle #pathology #cardiology #physiology

Комментарии • 56

  • @doctorbhanuprakash
    @doctorbhanuprakash  5 лет назад +3

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  • @madyycool9904
    @madyycool9904 4 года назад +27

    love you from left ventricle 😁

  • @hanans6710
    @hanans6710 5 лет назад +7

    Very Informative, EASILY understood and digested!!! Thank you, you're the BEST!!!!

  • @drshaheen6352
    @drshaheen6352 2 года назад +3

    So Nice sir in a easy way.
    I need whole lecture on cyanotic and acyanotic heart diseases

  • @RaheelaSarwat
    @RaheelaSarwat 3 месяца назад +2

    Awesome

  • @ikshwakumohapatra8339
    @ikshwakumohapatra8339 7 месяцев назад +2

    Thank you so much Sir for this awesome video & clearing my concepts🙂🙏🏻

  • @rushabh191187
    @rushabh191187 3 года назад +4

    How long can a person survive on a minimum basis before ASD closure and after ASD closure ? Is the person out of danger after ASD closure surgery ?

  • @GoEunbeol_049
    @GoEunbeol_049 2 года назад +1

    From Kenya we say ,Asante sana

  • @abdullahyousafzai9397
    @abdullahyousafzai9397 3 года назад +2

    Thank you sir.!
    Respect from Pakistan

  • @NargisAkhtar-j6h
    @NargisAkhtar-j6h 12 дней назад +1

    Thank you sir❤

  • @goodvibeonly9771
    @goodvibeonly9771 Год назад +2

    Very well explained sir

  • @tharajuliet7591
    @tharajuliet7591 Год назад +2

    Great teaching. thankyou Dr.

  • @stupidsingh8148
    @stupidsingh8148 5 лет назад +3

    you style of teaching is very good luv uhh sir 😗😗thnq i don't have words

  • @petevhn
    @petevhn 2 года назад +1

    Good lecture. Suddenly reminded me of Conrad Fisher.

  • @kawthardjo1010
    @kawthardjo1010 5 лет назад +1

    Thank you so much very well explained

  • @محمدسعيده-و5ع
    @محمدسعيده-و5ع 2 года назад +1

    Thank you dr

  • @مسكالختاممحمد
    @مسكالختاممحمد 4 года назад +1

    Thank you so much doctor 💛💛💛💛💛💛💛💛

  • @طبيعى
    @طبيعى 7 лет назад +2

    very nice ,thanks

  • @Handle_symphony
    @Handle_symphony Год назад +1

    Ty 🩵

  • @hudafatima6496
    @hudafatima6496 7 лет назад +2

    thank you so much sir

  • @فهد-ع7ث9ر
    @فهد-ع7ث9ر 3 года назад +2

    Yei

  • @jenifertamang7011
    @jenifertamang7011 3 года назад +1

    Thank you sir

  • @purshottamvenkateshvenkate9645
    @purshottamvenkateshvenkate9645 6 лет назад +1

    Thanks sir

  • @chenura
    @chenura 3 года назад +1

    Nice explanation

  • @ktechnical3577
    @ktechnical3577 3 месяца назад

    Sir in asd case creatine increase?
    Because hypertension is high.

  • @FathimathHabeeba-tu6bu
    @FathimathHabeeba-tu6bu Месяц назад

    ASD with left to right shunt

  • @prarthana7021
    @prarthana7021 6 лет назад +1

    nice

  • @jenifertamang7011
    @jenifertamang7011 3 года назад +1

    Sir I want the notes of ventricular septal defects

  • @yunus2163
    @yunus2163 4 года назад +1

    cik cik

  • @kiddotv8681
    @kiddotv8681 3 года назад

    My baby have 3mm asd and 2mm vsd plz tell me what to do

  • @irfanucs
    @irfanucs 6 лет назад +2

    great thanks Dr. i have my 7 year child with "large secundum ASD RVVO"( conclusion on report 22x17x19 mm)

    • @ssoni429
      @ssoni429 3 года назад +2

      Hope your child is healthy ,,, did u treatment your child

  • @vikasyadav4251
    @vikasyadav4251 5 лет назад

    Why blood is not going from right atrium to left atrium ??
    If left atrium have low pressure than right atrium it should go from right to left.

    • @ilirtanku9722
      @ilirtanku9722 5 лет назад

      before birth the blood go from right to left because the pulmons are off and their resistance is higher.after birth when there is no more placenta for the blood to oxygenate the pulmons open and their pressure go down and now the shunt go left to right

  • @RajneeshVaid
    @RajneeshVaid 6 лет назад +1

    ✌✌✌✌👍

  • @gejalakshmis8407
    @gejalakshmis8407 7 месяцев назад

    I am asd small size 9month pregnancy now...deliveryku issue varuma sir

  • @user-bv1mh6fr1u
    @user-bv1mh6fr1u Год назад

    0:07

  • @فهد-ج4ح1م
    @فهد-ج4ح1م 3 года назад +1

    H

  • @chiragbaraiya2521
    @chiragbaraiya2521 Год назад +1

    Thank You Sir🙂