Does ZOE work? The results of our study | Tim Spector & Sarah Berry
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- Опубликовано: 12 май 2024
- Watch the full episode here: • Does ZOE work? Here's ...
We put our reputation to the test in a clinical trial. The findings confirm what 150k+ members already know: ZOE works.
The study is called Measuring Efficacy Through Outcomes of Diet, or METHOD, for short. Our scientists recruited 347 generally healthy people who were representative of the average adult in the United States. They had above-optimal body mass index (BMI) and waist circumference and were aged 41-70.
Jonathan sits down with Dr. Sarah Berry and Professor Tim Spector to ask what the blood and gut microbiome results revealed about the impact of ZOE’s personalised nutrition program compared to generalised dietary advice.
Learn how your body responds to food. Take our FREE quiz 👉 zoe.com/podcast
Books:
- Every Body Should Know This by Dr Federica Amati: amzn.to/4blJsLg
- Food For Life by Prof. Tim Spector: amzn.to/4amZinu 
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During the past 2-1/2 years, I’ve lost 85 pounds without surgery, medication or paying for a membership or program. I eliminated ultra-processed foods, added sugars, and fast food. I followed Keto for six months and have since followed the Mediterranean diet for two years. No blood glucose monitor. No keto meters. I have semi-annual blood and urine tests. My HbA1c went from 6.3 to 5.1. My HDL, LDL and VLDL are within reference ranges. My triglycerides, fasting insulin and liver enzymes are well within reference ranges. I’ve educated myself by reading nutrition articles from the Cleveland Clinic, Mayo Clinic and NIH. I watch a curated list of credible, academic RUclips channels. It doesn’t take willpower. It does require imagination and visualization to see a better way to eat. I got a jolt of inspiration from being diagnosed as pre-diabetic with non-alcoholic fatty liver and metabolic syndrome. I’m in my 60s. It is not too late to change.
@@user-zu2ir6sd1q Interesting. For me, it was a simple calculus. Eating high quality, minimally processed foods is more expensive than eating the standard American diet with ultra-processed food. The cost of remedial medical treatment is high - namely those to treat atherosclerosis, liver disease, etc. I am focused on healthspan…not lifespan. I don’t feel the need to pay to participate in a program. If they want to study me, I want them to pay me. 😂
Congratulations and thank you for sharing your story - it's never too late.
@@darlenes520 We are not all as smart and insightful as you. 😂 I simply don’t need a membership or an app to plan my meals and activity.
I have been on the Zoe Nutrition plan for over 12 months now. I have naturally lost weight, gained more energy, have clearer skin, reduced my UPF intake to at least less than 5%, all things as a result of knowing and understanding my own personal responses to foods. Amazing, changed my life and improved my health no end! 💛
This is amazing to hear, Becky. Thank you so much for sharing, it's truly a way of life! 💛
I lost over 2 stone after wearing the glucose monitor and changing my diet as a result, probably out of fear rather than will power. I had no idea what I had been doing to myself. I have no desire to eat the food I used to eat now. Started to eat fermented food also. I feel so much better mentally and physically now. I thought I was just getting old. Thank you so much Zoe although those muffins almost killed me 🤮
Lol about the muffins. I had the cookies but they were also very hard to eat.
The muffins!! 😂We've switched to cookies now, you may be relieved to hear! So happy to hear that you've experienced such positive changes.
❤
Thanks for the hard work Tim, Sarah and Jonathan. Been watching since 2020 and it's fantastic to see the consistency of research continue and charming to see the banter develop between you all.
Thank you very much for the support, Martin. We definitely have a strong rapport with each other!
I think Zoe needs to put more emphasis on the “now” benefits. It’s great to hear about the risk reduction for your future self, but it’s not all “jam tomorrow”. Feeling more energetic, clear headed and happy means such a lot.
The results are not surprising to me other than the less hungry part. This is important and impressive work. Hoping that the data will be available for other scientists to conduct secondary analyses..
Thank you so much, Dr. Tonya.
If you want to know if the personalisation promised by Zoe works, you give everyone the same level of support, have people randomised into a Zoe personalised diet and a sham Zoe diet. Only then does the trial tell you anything about the “Zoe program“ per se. If you only want to find out whether having an app plus support system works, give only one group the support. Wouldn’t tell you much beyond “it’s helpful to have lots of support”, but still… What such a trial WOULDN’T tell you is whether the Zoe protocol as a whole works.
I think you need to listen again to the talk. Start at 1.25
Is there a way to sign up to be part of the study? If not, do you have your protocols so I can follow the program by myself?
Is it the nutritional advice or the checks and balances promoting adherence. We all consume things we know we shouldn't. Trying to stop this by yourself is difficult. Don't know about giving your information to business is the best. I guess if you don't have anyone in your life that is trying to get healthier, and you can discuss things, you may have to give your information to one of these things
This is Tim's howto. ruclips.net/video/BPI-FJj8f5o/видео.html
Hi Kathy, you can sign up for a ZOE membership here: zoe.com/how-it-works and you can also check out our Health Academy for more free science resources to get you started on your journey: zoe.com/learn
I have been subscribed for some time but quite frustrated that, despite all the talk about ‘the Zoe program’ and the Zoe ‘advice’ I still am confused about specifically how to eat! Tim and Sarah often talk about how differently they eat but what do they have in common? Now you have the evidence of efficacy it is surely time to make the program more widely available to all of us frustrated and impatient people outside the UK/US. I would really appreciate more details and specifics on what works and what doesn’t for pretty much everyone.
Figuring out how to not eat what you know you shouldn't, is a big part of it
Hi Linda, we have some excellent resources in our Health Academy that will probably be very helpful. Here's the link, we'd recommend starting in the 'Nutrition' section: zoe.com/learn
This sounds extremely good and very useful. I have followed the day log in zoe and keep a close check on diet. I have found, just doing what I have done has made a real difference.
We're really happy to hear it's making a big difference for you!
How did you account for people like me who followed the programme but got negative outcomes on almost all claims so stopped before completion? I was a self-selecting failure of the programme.
Glad you’re setting high standards regarding your study findings. Others should take note! The hiding or distortion of “unfavourable” outcomes / data…that could jeapordise a company’s future…and the (often very comfortable) livelihoods of those involved..should never happen and is morally reprehensible.
Thank you for the support, Steve!
I got my HbA1C down 5points when I stuck to Zoe rigidly but I could not maintain my body weight, I’m still outside the prediabetic range but it has gone back up 4 points.
Please make it available for people with coeliac disease and other bowel diseases to see if we can improve our gut health
Hear! Hear!
Hi Josie, unfortunately coeliac disease is part of our exclusion criteria because it is classed as a medical condition and not something that we can comment on or have done any research on. Because of this, it is not ethical for us to offer nutritional guidance and it's best to seek advice from a dietitian. We're sorry for any disappointment but hope you can still gain valuable knowledge and insights from our free resources. We hope this helps explain.
I would like to have a clear comparison between strict adherence to healthy diet guidelines and strict adherence to a Zoe program. What is the benefit of *personalized* diet instructions and coaching (compared to a healthy diet without personalization)?
How would Professor Tim Spector eat differently between 1. Knowing what he knows vs. 2. Having Zoe feedback on how to personalize his diet to himself?
You need feedback. Some people have others that they can get it, some don't and need an app. It's the only way to stop consuming what you know you shouldn't be.
@@brucejensen3081 I'd like to see real data comparing before/without Zoe feedback to after/with feedback. What actual food changes were recommended?
@@woofinu if you watch enough of their stuff, I think you can get a fair idea what the changes would have been.
@@brucejensen3081 I have followed Zoe broadcasts since the beginning and have the latest book by Professor Spector, and am familiar with Zoe general diet guidelines. My question was about examples and specific benefits of Zoe personalization that go beyond those general guidelines. If you know what they are, great.
@@woofinu I suppose it would be different for each person, depending on how bad their current diet is.
is it true that instead of using a controlled, double-blind, randomized trial, you designed the one in which the Zoe program will always do better than “control”?
When are you going to make The Zoe programme available in Ireland please ??
We don't have immediate plans to expand yet, but hopefully we can continue to spread our reach in the future!
Is there any evidence that continuous glucose monitoring in non-diabetics is beneficial in the long term? Is there an increase in anxiety amongst the users?
Where can we see the published paper? 🙏
Right here, enjoy the read! www.nature.com/articles/s41591-024-02951-6#:~:text=In%20this%20randomized%2C%20controlled%20trial,%2C%20but%20not%20LDL%2DC.
Where can I find the Zoe program
You can find it here: zoe.com/ and here zoe.com/how-it-works 🙂
When will it be available in the nordics?
We don't have immediate plans to expand yet, but hopefully we can continue to spread our reach in the future!
When will it be available in Germany?
We don't have immediate plans to expand yet, but hopefully we can continue to spread our reach in the future!
Is this an ad ? there was no explanation of who they are or why they are here?
Hello, you can learn more about us here: zoe.com/ and here: zoe.com/how-it-works