Making Lidocaine To Rizz Up The Dental School Baddies
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- Опубликовано: 8 янв 2024
- Today we make lidocaine so I can finally get a girl. I heard the dental school baddies use lidocaine in their practice, so this has to be the best rizz gift EVER. Enjoy my chemistry kings and queens.
Sources:
www.cerritos.edu/chemistry/ch...
people.chem.umass.edu/mcdanie...
www.diva-portal.org/smash/get...
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I love how you give 4 significant figures percent yields with 2 significant figures weights. I wonder if you do it to piss stuck-up chemists off😂
ikr what a madlad
Dirty lidocaine and the Mother Liquors would be an awesome band name .
My tooth hurts so bad, so I came here for the mind-numbing lidocaine humor. :D :D
@Chemdelic - in case your chem career fails, you're guaranteed success in stand up comedy... it's off the hook yo! lol
I could see them opening for Amyl and the Sniffers
Add king gizzard and the lizard wizard to that line up.
Just had this stuff today at my dentist. I think at least this is what they are using, it has an intense bitter taste I know. Speaking of cool band names related to this substance I remember from an album that I got in the 90s : Nordic Rave, a group named Xylocain wich is a trade name for Lidocain. This is their tune Going Nowhere from that album and its awesome! ruclips.net/video/9XCEw5oYvhY/видео.html
finally someone who got into chemistry for the right kinda reasons. im sick of hearing "oh i started coz i want to save the world or cure cancer". no, i needed an icebreaker with the hot girls. nice
I mean truely anybody who says they got into chemistry for a reason other than it’s just cool as fuck is lying to themselves
@@Misterme333three reasons anyone gets into chemistry: get high, explode stuff, play god (save lives)
@@Misterme333Very true
9:33 styro pyro impersonation 10/10.
Lmao through most of this video. Great episode. Been using lidocaine alot here recently.
first it was artificial flavorings to get the girls, now its numbing agent to get the girl, what's next microwave some rubies to rizz up the girl?
Antibiotics .
Microwave rubys to propose to the girls! 😉
Chloroform, obv.
@@theKashConnoisseur Chloroform doesn't actually work like that, wish I'd known before I tried it.... 😞😁
Benadryl
This is the first time I’ve heard a chemistry RUclipsr say “Rizz.” I am terrified what this guy is going to create in the future
Well... mohr Rizz yo! :D
Fear not, this man is totally sane
not much worse than NileRed
Cyanide, probably
hes trying to create benadryl and ALMOST make MDMA up to the point its illegal
I love your content, perfect blend of science and shitpost, cant wait for the hatman special
Space heaters are one of the unsung heros of amateur chemistry
Yup, keeps them honies warm. ;D
Next go for the "horse girls"
Making horse tranquilizer?
turn a horse into lidocaine and give it to a horse girl
@@-w-. I think he means phosgene
@@-w-.Ketamine?
Ketamine? Good idea.
I really like these unique syntheses. From scary reagents to pretty colors, this was very satisfying to watch and I really enjoy when you explain the reaction mechanisms. GOAT! 😌
Now lets do tropococaine. Then lets do a series on unscheduled amphetamine salts
I like the cut of your jib, son
the purple impurity may be related to your carbonate; I recently carried out an unrelated reaction (formaldoxime from formaldehyde + hydroxylamine, using sodium carbonate to get basic conditions) and got a really deep purple colour at first, that faded on heating
strangely, when it cooled down again it became an orange/brown colour
You decomposed formaldoxime to hcn?
@@bobsagely812 no, I reduced it to methylamine - unlike your man the OP, I have no easy way to get hold of pure nitromethane and this is a pretty efficient alternative
I had a very attractive and well endowed female dentist , she had a lot of trouble getting out one of my molars. she really had to put me in a headlock and yank my head all around, it was the most fun I ever had at the dentist😅
I, uh, don't know how else to ask you, but is this your kink?
1:20 I appreciate your transparency.
I feel like you do this a lot. way more than any science youtuber I watch.
🤣 Your dry wit makes these videos quite funny. Really enjoying your content. Ty
THE SHADOW FIGURE'S LAND AWAITS
Literally got a tooth pulled the same time this video dropped! hahaha. NEAT STUFF HERE DUDE.
Like a Dutch saying goes "it is always spring in the eyes of the dentist assistant". The perfect use of chemistry in my opinion
For the diphenhydramine synthesis don’t use α-bromodiphenylmethane. I couldn’t get it to work. IIRC, Thyzoid tried using that as well, and got the same result I did. I think you have to use benzhydrol. There’s also a nice easy procedure for making benzhydrol in Vogel (reduction of benzophenone with zinc and NaOH in ethanol). N,N-dimethylaminoethanol is also sold as a supplement as the bitartrate salt. It’s called DMAE bitartrate. I found that heating it in methanol with NaOH, filtering to remove the sodium tartrate, and distilling off the methanol was a decent way of isolating freebase DMAE. Can’t wait to see what you come up with!
I actually found a different way!! First I’ll reduce the benzophenone with sodium borohydride, then there is a patent that used tosic acid, toluene, and DMAE to make it. Really cool stuff! Also I literally just got done with doing DMAE synth haha. Though That Chemist showed me a way of using sodium ethoxide in ethanol to get the DMAE freebase rather NaOH. I got some stuff, but I need to fractionally distill since it likely formed a azeotrope and distilled over around 90C. Hopefully that fixes it.
@@chemdelic Awesome! Did you use Eschweiler-Clarke methylation of 2-aminoethanol to prepare DMAE? If you have any you can try adding 4A molecular sieves before distillation to remove water, ethanol, and methanol if there's any in there. That might help because if it came over as an azeotrope then you're probably not going to be able to purify by distillation alone.
I suggest giving the zinc reduction of benzophenone a try instead given that NaBH4 is more expensive, and harder to get than zinc. The procedure is listed under Exp. 5.30 on page 523 of Vogel's Textbook of Practical Organic Chemistry. It takes about three hours, and gives good yields. They claim a crude yield of about 96% (m.p. of 65 C, and 68 C after recrystallization) which is about what I got as well. Plus it forms a deep blue color after adding the zinc which is nice. If you don't have a copy of Vogel I'd be happy to send you a copy of the procedure if you ever want to give it a try.
Good luck with the synthesis. I can't wait to see it! Thanks for making these videos too. Maybe it will give me the motivation to retry the diphenhydramine synthesis someday; once I get around to finishing my rizatriptan synthesis some time in the next decade anyway.
Solid concept tbh, honestly sounds like a top-tier, machievellian level scheme.
Making Propofol to get the girls! And on my next series making fentanyl to make new friends.
8:35 Chemdelic having diethylamine for non-suspicious reasons
I like the new videos, better framing, lighting and pace.
I don’t understand shit about chemestry but it’s relaxing.
You should stir your crystallization liquor with a stir bar at small scales. It promotes consistent particle sizes, mitigates how much you need to scratch the flask, and reduces impurity inclusion. So few chemtubers agitate their crystallizations. The real pro-gamer move is find the supersaturation window and pitch seed crystals then doing a controlled cooldown and/or antisolvent addition.
Watch glass is used for that to get seeding crystals for process initiation. Seedin is done on the flask wall right on the air-liquid interface. It does not normally result in disolving of the seeding crystals introduced.
Aromatic amines like to make purple oxidation compounds. Your dimethylaniline got oxidized during the processing. Reminds me of Perkin discovering mauveine (the first synthetic dye) by oxidizing a mix of aniline and toluidines with dichromate.
Hey at least it ain't "yellow chemistry". :D :D
@@BillAntif yellow chemistry is evil and purple is the complementary color of yellow, then purple chemistry is best chemistry
and here I thought it was some exotic organotin complex
@BillAnt I think you mean “piss chemistry”
THATS WHY HE’S THE GOAT 😭
....you are the GOAT!
I'm bookmarking this video to casually watch while I'm waiting for the dentist on my next appointment...😉🤞
Quality production 👍
Thank you for lidocaine synthesis with aloe it worked on my sore.
Omg I cracked up so bad at your styropyro impression
we appreciate your realness
Considering the shelf-life of many of the painkillers commonly used for surgeries, having local processes in place to turn out pharmaceutical grade drugs might be prudent in case anyone decided to shut down trans-pacific shipping.
I gave the hat 🤠 man a black eye 👁️ now he wears sunglasses 😎 at night 😂
I love your videos
Please make a video on making Oxiracetam
i love the glacial acetic acid videos
Tin reduction normally affords amino complex with tin chloride salt. Tin 2 chloride is used when you need selective reduction which is not the case for this particular nitro-derivative, most likely Sn metal cold be used instead of SnCl2 for economic purpose.
Dude i subscribed JUST for your fucking video titles.
cant wait for the diphenhydramine vid
These ai generated pictures of people give me goosebumps. Pure nightmare fuel
back shot wind 😂 dirty cut 😂
Now whatever you do don't use it to smoke da rock
I have to synthesise this and make a full report on it as part of my undergrad in a few weeks, giving me more reasons now
DOUBLE U!!
13:25: That's Diphenhydramine, isn't it? Sounds interesting.
W RIZZ! VENTELATION YO!
Bro u gotta sniff that ether not evaporate 😂😂❤️
Glacial acidic acid is super dangerous. At my factory you need a respirator to handle it.
55:00 my world ended. I always thought that glacial sallysilly acetic acid was from the tears of melting glaciers.
is that little table the jack for a dewer? I never noticed
W for ventilation!
why no side product from attack at the alpha carbon of chloroacetyl chloride when you add the dimethylaniline
Dental school badies are actually very much more approachable than those pharmacy school badies. Speaking from experience
The title for this video is my favorite kind of clickbait title lmao
That's fucking hilarious
backshot winds is Crazy bruh
To get even more precise with a syringe you could try it like I do (note I'm a total armature with zero formal training.. so yea.. correctness/details on you).
You just start with more air in the tube.. like I get that emptying it before drawing in stuff is, well, common sense..
but if you then you can draw in exactly 1.75ml (view un-obstructed by plunger),
and then (assuming you keep it upright the whole time), you can flush it all out with the stored air.
Do “making anabolics to Rizz the gym bros” next plz
Nice video! Did you think about using Iron with ammonium chloride for the reduction to avoid using tin?
Do you have a couple of good referaces for this reaction where the procedure applied to at least a few examples?
@@user-uk3nx8cn4u won’t let me post a link but if you go to the website “common organic chemistry” there are a few procedures on there. Off the top of my head I’ve added around 5 equivalents each of Iron and ammonium chloride and stirred in ethanol at room temperature overnight and worked great.
Not the hatman 😭😭😭
Helional to MDP2P or piperonal. That'd make a great video. I know the MDP2P might seem suspicious but it's technically completely legal to possess. As long as there is no ill intent of course. I can help you with this. Id bet that would be one of your most popular videos.
I was very surprised at the idea that MDP2P might not be illegal (according to the DEA at least), so I looked at a bunch of official DEA lists of controlled substances and none of them mention MDP2P, PMK, 3,4-methylenedioxyphenylpropan-2-one, etc. However, almost all of these lists also say that while a given chemical may not be specifically listed, analogs and precursors are still illegal.
I definitely would like to see how this would be prosecuted and how a defense for someone, say, producing and selling MDP2P would work in court.
It seems like a gray area lol (which is why chemistry is awesome!)
Next time you should use a more natural approach by extracting local anesthesia from some bushes in Columbia
Thats for eye doctors and ENT surgeons.
It turned purple because dental students like pretty colors.
I brush my teeth with lidocaine and toothpaste...long story, but I got damaged teeth, that resulted in cavities, that is pretty painful.
Any particular reason to use KOH and not NaOH?
bro that intro 🗿
I think you get more girls with procaine.
now do a short denatonium benzoate with taste test
Benzocaine brother
No way you’re making diphenhydramine in the next vid 💀
Eventually :)
@@chemdelic Hahaha ty I’d love to see it
What happened to synthika chemicals?
BRO IS GOING TO MAKE DPH 💀
Tin causes purple in acidic solution
Let’s gooo! 🥳🫶🍻
bro please i need the piperonal from vanillin part 2😭
Soon my child 🙏
I was always taught to pour the top phase out of the top rather than use the tap for both in a separatory funnel, is that just me?
Just being picky but the formula at 2:52 is for aniline, not dimethyl aniline
Damn I knew I would make a mistake somewhere 💀
There's another one later on but eh whatever, it was a fun video to watch :) Thanks for uploading @@chemdelic
I bought 100 grams of benzocaine in crystalline form on Amazon for a project.
Diphenhydramine?
Your next video is going to be on diphenhydramine?
It was but I have to switch some things around since I have a sponsor video coming up!
Frank Ocean smoked Novocaine with his baddie, not lidocaine lol. Still fascinating video!
Hi, i really love your work and i really want to start doing my own reactions but i dont know where to start, could you maybe make a video about the information gathering process? That would be unbelievable helpful
was that a normal space heater? dont u know about the teenager with a knack for engineering that is revolutionising the billion dollar heating industry after his school kicked him out.
Making coke to impress a pre-depression girls
The purple is probably tin acetate
oh god not the hat man... deleriants are scary ngl, never seen the hat man but boy were there spiders. dph i assume?
As a bonus you could use it to help a premature ejaculation problem that you definitely dont have.
Its a gift for him AND her!
YOURE MAKING BENADRYL!??!?!
Eventually yes!!
2:56 the formula in the top left is for aniline HCl not dimethylaniline HCl
Yeah I totally forgot to change that💀
By hat man you mean....benadryl?
I dont know why but watching the Video on fullscreen on a smartphone does not show the fullscreen but a 6/8 cut or the Video
Wait, did another of your videos disappear?
No but I did change thumbnails!
Why didn’t you use Pd/C (palladium on carbon) and ammonium formate?
I followed an online procedure that used SnCl2 :)
W
1:00 W
Diphenhydramine??
UU
He said spam double U, Right?
Hi
Nice job, but you should characterize your compounds and not jsut saying " Ok, this is X ". Anyway, aromatic amines are knows to oxidize in presence of air, acid, bases, light, heavy metals. The oxidation products are polyamines which tend to be black. In fact, aniline, a colorless liquid, turn quickly yellow when exposed to sunlight or even ambient light in air, and with more time then red, brown and lastly become a viscous total black liquid. Laboratory purification are realized by distillation in Kugelrohr.