Next Generation Sequencing 1: Overview - Eric Chow (UCSF)

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  • Опубликовано: 24 ноя 2024

Комментарии • 222

  • @hansvanlennep6376
    @hansvanlennep6376 5 лет назад +277

    Finally! Someone that clearly explains the basics of NGS in a understandable way. Thank you very much!

  • @anonviewerciv
    @anonviewerciv 4 года назад +71

    7:47 Illumina.
    21:00 Nanopore.
    23:23 Pacific Bioscience.

  • @mayureshvishwanathan6458
    @mayureshvishwanathan6458 Год назад +3

    I was hunting for a start to understand basic Next gen sequencing in a easy way and finally got to watch this video. Thank you very much

  • @journeymansix
    @journeymansix 2 года назад +5

    This is the most lucid explanation of next gen sequencing I've seen. Thanks, Eric!

  • @rebelScience
    @rebelScience 5 лет назад +79

    Thanks you so much for this! I am a professional programmer, transferring my skills to Bioinformatics on my own. This information is phenomenal. Please do more presentations in this manner.

    • @emekudoh5650
      @emekudoh5650 7 месяцев назад

      Would love to have a connect if you don't mind. Thanks

  • @Lenz979
    @Lenz979 5 лет назад +26

    Eric Chow! Great video. Never seen anyone explaining NGS so well as you do. Impressive. Thank you for your efforts! Please keep on making these videos!

  • @ThePoptartjunkie
    @ThePoptartjunkie 4 года назад +8

    Fantastic presentation. Its always great to see someone keeping it simple, but simplicity goes a long way. You have educated so many people!

  • @inshaishrat4371
    @inshaishrat4371 11 месяцев назад +2

    The best video on NGS ever!

  • @marchielumsy1673
    @marchielumsy1673 3 года назад +1

    This is such a clear explanation of how these sequencing technologies work. I was focused the whole time. Great work!

  • @antonioaugustolimateixeirajuni
    @antonioaugustolimateixeirajuni Год назад +2

    I loved this video and how you clearly explained all the basic concepts about NGS

  • @jixingliu9501
    @jixingliu9501 Год назад +2

    Great video! I have messed up details of NGS for many years until seeing this video.

  • @robelbelay4065
    @robelbelay4065 5 лет назад +43

    Absolutely fantastic presentation! Very clear and concise. Thank you

  • @mitalipandey3799
    @mitalipandey3799 4 года назад +1

    This is a very well thought through and presented video. All the concepts have been researched and presented in a very palatable manner with no frills (background music).The speaker also has very clear diction and doesn't make any unnecessary movements. This allows the viewer to actually see what is being referred to instead of the speaker covering it up. Please keep making and posting these videos - they are very well made and informative. All the best.

  • @danielzarate64
    @danielzarate64 2 года назад +1

    Thank you!!! That was by far the best breakdown of how NGS works!

  • @rahulboh
    @rahulboh 5 лет назад +8

    So comprehensive and simple to understand, what a great resource. Thank you and Kudos Dr. Chow!

  • @SnappyScience
    @SnappyScience 2 года назад +1

    This was exactly what I needed. A clear explanation of NGS, how it works and why it's important. Thank you!

  • @melix196
    @melix196 3 года назад +3

    No textbook nor lecturer explained this better. Thank you so much for this high quality video and the recordings from the lab made this video extra interesting ☺️

  • @ParisaAarabi-b4f
    @ParisaAarabi-b4f 3 года назад +3

    Your presentation is MARVELOUS! Thank you so much for explaining it simple enough to allow me to walk through it with my high school knowledge!

  • @juancarlostantalean6496
    @juancarlostantalean6496 4 года назад +2

    Thank you very much Eric !!. I am professor and it is so good for be used in class of Molecular Biology about NGS sequencing. Best regards from Ica-Perú, the place of Nazca Lines !!

  • @flaviorump607
    @flaviorump607 4 года назад +12

    Thank you, Eric and iBiology team for a very well-produced and thorough video. My exam prep just became more fun :)

  • @SZM396
    @SZM396 Год назад

    Highly recommended to watch. very clear and detailed. thank you for your efforts.

  • @liamnicholas97
    @liamnicholas97 Год назад +1

    What an excellent lecture -Thank you Professor.

  • @wanderingmanz
    @wanderingmanz 3 года назад +2

    Very well explained. Truely professional and takes along the students of all background knowledge.

  • @AsfandyarAfridi
    @AsfandyarAfridi 2 года назад +1

    GOAT video on sequencing

  • @lbgrindel
    @lbgrindel 2 года назад +1

    Great video. I liked the explanation of alternatives to Illumina. Never knew they existed.

  • @valentinarunko67
    @valentinarunko67 4 месяца назад

    Excellent lecture, far more useful than most other videos RUclips has on the topic of NGS

  • @Anetpersa
    @Anetpersa 5 лет назад +8

    I fell in love with molecular biology and chemistry again 😍 Thank you for this amazing video.

  • @speak_up_abu
    @speak_up_abu 2 года назад

    Just precious way of teaching

  • @sdsa007
    @sdsa007 2 года назад

    Thanks ... I know I watched this before... but its so clear and basic that I watched it again! Thanks for the refresh!

  • @PelleSenior
    @PelleSenior 3 года назад +1

    Nice job. This was very understandable, yet thorough enough to get a sense for the caveats of different methods.

  • @zhenli2293
    @zhenli2293 4 года назад +3

    This is great! Professional explanation and smooth and logical flow, which makes it very easy to understand.

  • @wenningqin4210
    @wenningqin4210 4 года назад +4

    Thank you for making NGS so easy to understand! Really appreciate your taking time to make this video and help!

  • @donthompson1517
    @donthompson1517 3 года назад +1

    Thank you Dr Chow! Your explanations are very clear.

  • @harshitashrivastava8877
    @harshitashrivastava8877 3 года назад

    Best video on Sequencing till date.
    Thank you 💯

  • @jsri1703
    @jsri1703 4 года назад +7

    Excellent teaching starting from scratch. I would like to have another tutorial from you about anchor, true sequencing primer and bar coding with math. I also didn't understand how in an open space a single spot have single (copies) amplified DNA segments.

  • @yibincao7924
    @yibincao7924 5 лет назад +7

    Dear Eric, fantastic NGS sequencing intro! Thank you!

  • @mechmania8450
    @mechmania8450 3 года назад +1

    I don't know much about organic chemistry but your explanation was really fantastic.

  • @esan120au
    @esan120au 6 месяцев назад

    Thanks so much! Even the illumina webinar was not as clear as your presentation! 👏👏👏👏

  • @tm67245
    @tm67245 4 года назад +1

    Clear and To the point explanation! thank you Dr. Chow

  • @bronaghmcdonnell8644
    @bronaghmcdonnell8644 Год назад

    Absolutely brilliant 🎉 I'll be watching all of prof Chows videos.
    The reference to suppliers and technologies was excellent, the historical context of Sanger Sequencing was really valuable to then appreciate newer methods, and the videos of the pieces of equipment used was so so so helpful to visualise how this happens in a lab, or on the moon. You covered alot with perfect explanation and delivery. Thank you. I've just started working in a genomics lab and this has helped me alot.

  • @rock3tcatU233
    @rock3tcatU233 3 года назад

    The future of this technology is very exciting.

  • @snowballandbubbles9379
    @snowballandbubbles9379 3 года назад

    The Best lecture on NGS! Excellent!

  • @chelseauju7685
    @chelseauju7685 3 месяца назад

    Excellent video. This is the best explanation for NGS and Sequencing in general! Thank you

  • @audairwashdeh9740
    @audairwashdeh9740 2 года назад +1

    Thank you so much for simplifying the mystery of NGS! A very helpful video.

  • @user-ko9rj8yg4z
    @user-ko9rj8yg4z 4 года назад

    Such a neat clear and crisp explanation

  • @razanalrawahi2291
    @razanalrawahi2291 3 года назад +2

    Omgg you just saved my grade!! thank you so much for this amazing work!

  • @CharlesChoMD
    @CharlesChoMD 3 года назад +4

    Great overview lecture. Thank you so much

    • @toms7695
      @toms7695 3 года назад

      Even our most educated Doctors have no weak concepts and low knowledge of DNA sequencing ! what an alarming time in medecine when we base our health on mathematics !

  • @izj-19
    @izj-19 3 года назад +1

    This was so clearly explained. Review of basics was really helpful. Thank you!

  • @ScottRobertsPage
    @ScottRobertsPage 5 лет назад +3

    Very informative video. This helped me understand how sequencing works much better than the videos from Illumina.

  • @carlosp.e.bedson4011
    @carlosp.e.bedson4011 4 года назад +1

    An amazingly professional and clear presentation. Thank you!

  • @sagek7949
    @sagek7949 3 года назад +1

    This was so very helpful. Thank you so much! This is by far the best explanation on NGS!

  • @Science.Medicine209
    @Science.Medicine209 5 лет назад +5

    Excellent and comprehensive presentation ..Thank you Doctor...Kindly Do more video like that specially on its Analysis

  • @yeeguan99
    @yeeguan99 2 года назад

    Thank you for the clear and consice lecture on NGS!

  • @skippyleif
    @skippyleif Год назад

    Excellent video! I love how concise and easy to understand this is. I am starting to analyze NGS data and this just made things much easier.

  • @franciscoagus
    @franciscoagus 3 года назад

    Congrats mate. You have some serious teaching skills.
    Quite complicated stuff explained very easy and simple.

  • @anp9929
    @anp9929 3 года назад +2

    holy shit my man you've done it to the fucking MAX i love you

  • @rzipper1716
    @rzipper1716 3 года назад

    This IS the best review of NGS ! Thanks !!

  • @wynnewijaya158
    @wynnewijaya158 8 месяцев назад

    Thank you so much for this, Eric! Very easy to understand.

  • @francescalittle
    @francescalittle 4 года назад +1

    Thanks to you, I FINALLY understand this topic! You explained it so well.

  • @CraftySmurf35
    @CraftySmurf35 4 года назад +1

    This was a great video. Please make some more NGS videos ! How about a series on microarray ?

  • @manoappapillai
    @manoappapillai 3 года назад

    Super . . very clear presentation. Please do more. Thank you.

  • @fdboucher
    @fdboucher 4 года назад +1

    Brilliant presentation! THANK YOU Eric!

  • @eliabd7726
    @eliabd7726 2 года назад

    I appreciate for all of your videos. Please make more videos.

  • @laworder5158
    @laworder5158 4 года назад

    Exciting future for NGS. Thanks for this great video.

  • @psculpta
    @psculpta 4 года назад +1

    Excellent job! I wish I could take a class from this professor.

  • @Rodrigo-yx3sn
    @Rodrigo-yx3sn 4 года назад

    Really good explanation and comparison between technologies.

  • @rahayupertiwi4299
    @rahayupertiwi4299 3 года назад

    Thank you so much for this clear explanation, Sir. If I can give a comment, please also share the material on the presentation so we can read it more clearly. Thanks

  • @MrViermeRau
    @MrViermeRau 5 лет назад +3

    Really good video, it made a lot of things clearer, thanks

  • @Iqertwyegcje
    @Iqertwyegcje 2 года назад

    Thank you, it helps me a lot to understand sequencing process

  • @pek972
    @pek972 3 года назад

    Excellent! To make so clear something that complex! Thank you very much.

  • @matt-g-recovers
    @matt-g-recovers 3 года назад +1

    This is outstanding!
    Thank you!

  • @dr.janmejaykpandey4802
    @dr.janmejaykpandey4802 5 лет назад +1

    Awesome (Very Comprehensible). Your Video helped me a great deal in my class on DNA sequencing.

  • @sawses
    @sawses 4 года назад +1

    Thanks for this! I'm a recent bio grad and wanted to figure out how NGS differs from Sanger. Well done.

  • @dabio3392
    @dabio3392 2 года назад

    Eric, you need to get an award/recognition for the quality of instruction you provided in these video series. It's incredible how you've distilled such a topic into something very understandable.

  • @rinm2564
    @rinm2564 2 года назад

    Thank you very much. It is the best explanation! Good luck in your work.

  • @Mrymena
    @Mrymena 2 года назад +1

    I have a question about the point at 11:00, which states that all the DNA molecules in a cluster are identical because all are copies of the same template strand. How does the system ensure that when the DNA strands are first introduced to the flow cells, you don't get multiple different template strands binding in the same cluster?

    • @joehickey1745
      @joehickey1745 2 года назад

      I would like to know this aswell

  • @negarolfati36
    @negarolfati36 11 месяцев назад +1

    10:48 How does this happen? How do the strands bend and make the U shape?

  • @delprice3007
    @delprice3007 4 года назад

    Outstanding presentation, many thanks.

  • @justg.5874
    @justg.5874 3 года назад

    Thank you. Used this to prepare for a job interview💛.

  • @mly2883
    @mly2883 3 года назад

    Thank you Eric, well explained.

  • @katelinklyn8335
    @katelinklyn8335 2 года назад

    Very interesting and easy to understand. Thank you!

  • @ainawatif1091
    @ainawatif1091 4 года назад

    it so nice. i could understand much better. Do pray for my master journey !

  • @Kat-lx7qq
    @Kat-lx7qq 2 года назад

    wow! this was fantastic thank you so much Eric

  • @ahmedhaji4416
    @ahmedhaji4416 4 года назад +1

    wow , this video and this explanation is just amazing , thank you very much .

  • @hesnayigit8840
    @hesnayigit8840 3 года назад

    Thank you very much, this is a great presentation of the systems.

  • @mervatel-deftar8412
    @mervatel-deftar8412 7 месяцев назад

    Amazing overview Excellent

  • @gokuln9159
    @gokuln9159 2 года назад

    Awesome session 🎉 Thanks

  • @nikolayanachkov4553
    @nikolayanachkov4553 2 года назад

    This was such a great video ! Thank you !

  • @CodeJeffo
    @CodeJeffo 2 года назад

    Excellent explanations. Thank you.

  • @dangthatscool1
    @dangthatscool1 2 года назад

    Great overview! Thank you.

  • @madhusudanm5835
    @madhusudanm5835 4 года назад

    great and very informative video presentation. amazing explanation.

  • @alimughal715
    @alimughal715 5 лет назад

    Realy very nice and understandable presentation.

  • @kareemjeiroudi1964
    @kareemjeiroudi1964 5 лет назад

    Thanks for this briefly well-put summary on NGS

  • @aqsasaeed5237
    @aqsasaeed5237 5 лет назад

    Excellent Explanation of the topic

  • @nicolaeionescu-kosa132
    @nicolaeionescu-kosa132 3 года назад

    Excellent presentation, could understand more things. Thank you

  • @natalyabeschastnova4049
    @natalyabeschastnova4049 5 лет назад +2

    amazing video! very detailed and clearly explained! thank you for making this video and posting it!

  • @kertamo6721
    @kertamo6721 2 года назад

    Truly a great presentation. Thank you :)

  • @MrLoveforGOD
    @MrLoveforGOD Год назад

    Dear Prof , thanks for the presentation, please am interested in training of Next generationa sequencing technology

  • @Eclyptical
    @Eclyptical 2 месяца назад

    Fantastic video

  • @sergepalekha9410
    @sergepalekha9410 4 года назад

    Eric your presentation slaps!