Orthokeratinized Odontogenic Cyst (OOC)

Orthokeratinized odontogenic cyst (OOC) was first described as an orthokeratinizing variant of odontogenic keratocyst (OKC) in 1981.
It is now known and accepted that OOC is a distinct clinic-pathologic entity on its own. In fact it has been listed as a developmental odontogenic cyst in the recent (2017) WHO classification of odontogenic cysts.
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References and further reading:
💡MacDonald-Jankowski DS. Orthokeratinized odontogenic cyst: a systematic review. Dentomaxillofacial Radiology. 2010;39(8):455-467. doi:10.1259/dmfr/19728573.
💡Speight PM, Takata T. New tumour entities in the 4th edition of the World Health Organization Classification of Head and Neck tumours: odontogenic and maxillofacial bone tumours. Virchows Arch. 2018 Mar;472(3):331-339.
💡Dong Q, Pan S, Sun LS, Li TJ. Orthokeratinized odontogenic cyst: a clinicopathologic study of 61 cases. Arch Pathol Lab Med. 2010 Feb;134(2):271-5. doi: 10.1043/1543-2165-134.2.271.
💡Shear M, Speight PM. Cysts of the Oral and Maxillofacial regions.4th ed. Blackwell Munksgaard;2007.
💡Neville BW, Damm DD, Allen CM, Chi A. Oral and Maxillofacial Pathology. South Asian ed. Elsevier; 2016.
💡Regezzi JA, Sciubba JJ, Jordan RCK. Oral Pathology: Clinical Pathologic Correlations. 5th ed. Elsevier; 2007.
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