EMBL Keynote Lecture - Of Neanderthals and Denisovans, Svante Pääbo
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- Опубликовано: 25 июл 2024
- Presenter: Svante Pääbo, Max Planck Institute for Evolutionary Anthropology, Germany
From the EMBO|EMBL Symposium Reconstructing the Human Past - Using Ancient and Modern Genomics
EMBL Advanced Training Centre, Heidelberg, Germany
31 March - 3 April 2019
Our laboratory works on methods to retrieve DNA from ancient bones and other tissue remains as well as sediments found at archaeological excavations. We take a particular interest in Neandertals and Denisovans, the closest evolutionary relative of present-day humans. We have generated genomes from a number of Neandertals and retrieved the genome from a small bone found at a site in the Altai Mountains, which turned out to come from a hitherto unknown extinct Asian hominin group related to Neandertals, which we named “Denisovans”. We have shown that gene flow occurred among modern human ancestors and different archaic hominins. Consequently, about 2.0% of the genomes of people living outside Africa come from Neandertals while about 4.0% of the genomes of people living in Oceania come from Denisovans. Some of the genetic variants inherited from Neandertals and Denisovans were advantageous to modern
humans and many are today involved in susceptibility to diseases. I will summarize our current knowledge about the functional consequences of such genetic contributions from archaic
hominins as well as recent work that begin to unravel the population history and interactions among Neandertals, Denisovans, and early modern humans. 
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Well done Svante! Here’s a Nobel for you today!🎉
Lovely talk in the most soothing intonation, answering all my questions as they cropped up, with logical replies.
Did the study on modified sodium channels publish yet from Hugo Zeberg? I cannot find it anywhere...
i have a doubt sir., at that time periods( 40 000 years ago) , what was the earth shapes..? i mean the distance between the continents ...
Significantly, the Ice Age was at an advanced stage, leaving sea level low enough to leave what is known as Beringia on dry land. That's the land bridge between what is now Siberia and Alaska.
@@donaldclifford5763 thank you sir.
You can't find this when you search for neanderthals, because it is spelled incorrectly as neandertals in the headline.
Thanks for your comment Harrie! "Neandertal" is the spelling that is commonly used in scientific publications - both neandertal and neanderthal are correct ways of spelling the word :)
Neanderthal, the original spelling, was derived from the German valley where Neanderthal fossils were first discovered in the 19th century. In 1901, however, the German name of the valley was officially changed to Neandertal. Some scientists and scientific publications have extended the change to the name of the species. Most have not.
Well I think for the sake of bringing this knowledge to the masses, it makes more sense to stick with the common spelling. Awesome video though and glad to see you changed the spelling. ;)
It's a debate going on with what is homo erectus and what isn't. Are we giving the species different names when there the same but have under gone environmental driven evolution giving them a different appearances.
I almost feel like pablo is going to say this one day about Neanderthals and humans one day.
We do see differences in races in legiments and others things in our immune systems and of course skeletons .
When interbreeding took place freely and it appears the three types merged, can we really talk about separate species? Or are they sub-species.
@@casteretpolluxLast century or so it's been too much of an urge to quantize everything and that's messed up taxonomy. over classification.
Get outside of 10k bc and it's Too messy for what they have tried to use and tbh it's outside of what the general public understands as a family.
Like your point, my bloodline may have indeed survived through what they call a cousin species.
Admix is off the charts no way to know what direction some DNA may flow in .its all guess work and assumptions.
,@@casteretpolluxI think we should just go back from us count the family genetic mutations as they have been working on and with that, we all share a most recent common ancestor and call it modern human family. Make your own field of study completely independent of anything prior. Leave the before to it's own field of study and classification. All the other theoretical stuff muddys up what people really care about and want to know.
@@casteretpollux We so have the means to trace back 7 billion peoples most recent connection they just like that. Even in the high quality DNA test of 2016 & 2019 the report ignores the most interesting results. They did regard the findings and try to make excuses in the reports.
Neanderthals did not die out, they evolved into Crow-Mangon, a forerunner to homo sapiens sapiens... And yes The old form of Neanderthals was breaded out...
AND well so did everything over 50 kg on the northern hemisfär. We had an near total extinction event at the end of last ice age...