How to calculate sample size in animal experiments.

How to calculate sample size in animal experiments. Sample size calculation in animal research. Simple technique to determine the number of animals for animal research experiments for ethical approval.How to calculate sample size in animal experiments,sample size calculation for animal experiments,how to determine number of animals for basic research,animal experiment sample size calculation,how to calculate sample size,animal experiment,research sample calculation,technique
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[@antarasengupta8614]

please provide the reference for this assumption of E range

[@anugrahray8964]

You mentioned that the value of E should lie between 10 and 20 and at a later instant you are saying that if value is less than 20, it will be not statistically valid. This is to some extent creating confusion.

[@DrArindamGhoshBiochemistry]

In the second case..it should be less than 10 not 20 😅
Less than 10 creates invalidity

[@anugrahray8964]

@@DrArindamGhoshBiochemistry Thanku Dr. Ghosh

[@sumavk1633]

Sir i am doing animal experiments for antidiabetic activity...i used 30 animals ...and grouped as 5 groups...is it fair?

[@researchneeds]

no add at least 10 per group, the animal may die during disease induction

[@DrArindamGhoshBiochemistry]

It's good as a bare minimum but if animals die then your data might be statistically skewed. Be careful about that.

[@rishabkumarmodi5959]

Sir do make videos on research and methodology

[@DrArindamGhoshBiochemistry]

Sure I will

[@rishabkumarmodi5959]

Interesting..

[@DrArindamGhoshBiochemistry]

🙂

[@boscomutatse9644]

What you have shown is the degree of freedom not the number of animal to be used. 3 animals in each group are not representative. There are other factors to consider

[@DrArindamGhoshBiochemistry]

For the conditions mentioned in the hypothetical study for that specific example it would suffice. And it would be appreciated if you provide answers to your critic if your intent is really to help the community!

[@sevetse949]

Can you provide bibliographic data that support this method? Thanks

[@wahyuaddinpratama2490]

Up

[@1adamgarcia2003]

Sir, where I can find the source for the method?

[@DrArindamGhoshBiochemistry]

You can search any published literature :)

[@a.s9509]

@@DrArindamGhoshBiochemistry It would be better to give at least one reference to back it up. The way we do it is by calculating Power in statistical software. Here, it's not clear to me why it should be 10-20 and where this number is coming from? What's the scientific logic behind it?