How to conduct forced degradation study?

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  • Опубликовано: 24 ноя 2024

Комментарии • 34

  • @ankushthakur213
    @ankushthakur213 2 месяца назад +1

    Stability indicating method meaning?

  • @hanumantgare1891
    @hanumantgare1891 2 года назад +2

    Very nice presentation and explain in very easy language.
    Thanku so much sir for your efforts.

  • @rohinikumar7065
    @rohinikumar7065 3 года назад +3

    Nice presentation sir and make video on what are facts effecting mass balance failure and solutions

  • @prashantpandit7806
    @prashantpandit7806 2 года назад +1

    Superbly Explained...👍🏻

  • @rahulgunjal663
    @rahulgunjal663 3 года назад +3

    Sir kindly make video on mass balance calculation in fd

  • @mrinmoysarkar4133
    @mrinmoysarkar4133 2 года назад +1

    Thanks a lot sir...it's really informative ♥️♥️🙏🙏

  • @PG12333
    @PG12333 3 года назад +5

    What is mass balance in FD study and how it is calculate

    • @LearnValue
      @LearnValue Год назад

      Plus or minus 5% is acceptable

  • @krish_krish354
    @krish_krish354 3 года назад +1

    If the compound melting point or boiling point near 45 degree can we conduct acid or base hydrolysis at 80 c

  • @mitalipereira446
    @mitalipereira446 3 года назад +3

    Sir,
    Please make video on finding LOD and LOQ of method

    • @rajeshpudi8795
      @rajeshpudi8795 3 года назад +1

      Linearity and sample concentration chapter available

  • @manishkharkwal6106
    @manishkharkwal6106 2 года назад +2

    Ur presentation was good.
    Please check as for evaluating purity / spectra in FD, PDA detectors required not UV.
    But overall content was good.
    Thanks for sharing

  • @sameer_shindeshinde3674
    @sameer_shindeshinde3674 2 года назад +1

    Ur content is good so don't show advertising in between video, it disturb during learning.....

  • @jnaniashok
    @jnaniashok Год назад

    Excellent..

  • @rahulchadha6795
    @rahulchadha6795 Год назад

    Is it possible to do FD on UV methods?

  • @modernmogli5155
    @modernmogli5155 3 года назад

    Sir what software is this you are using , its very nice way to explain

  • @krish_krish354
    @krish_krish354 3 года назад

    For themal degradation dry method sample alone heated. For wet method with sampl wt will be added

  • @verans7152
    @verans7152 Год назад

    Thanks sir

  • @madhavikatta2150
    @madhavikatta2150 2 года назад

    Well explained sir thank you 😊

  • @kishordangat684
    @kishordangat684 2 года назад

    Good presentation

  • @pankajshah1084
    @pankajshah1084 3 года назад

    Nice video sir, very useful

  • @sanketdalvi2942
    @sanketdalvi2942 2 года назад

    Thanks sir....,❤️

  • @supriyabhamare06
    @supriyabhamare06 Год назад

    How to select drugs for FDS study

  • @rohitkhade4060
    @rohitkhade4060 3 года назад

    How to perform normal phase force degradation study

  • @ShikshanAcademy
    @ShikshanAcademy Год назад

    Pls put pdf

  • @mohdazeemuddin8353
    @mohdazeemuddin8353 Год назад

    Hi sir
    This is Azeem
    My Question is
    We have controlled Nitrite content in water NMT 0.03ppm
    Secondary amine is there
    Nitrosamine is possible pls suggest
    Provide the guideline

  • @PG12333
    @PG12333 3 года назад

    Sir please make videos on process validation

  • @krish_krish354
    @krish_krish354 3 года назад +2

    While conducting acid hydrolysis sample with hcl added. With this diluent added and kept in oven for degradation.
    Diluent added means how much should add before keeping in oven for hydrolysis.
    Can anyone reply please

    • @pharmagrowthhub3083
      @pharmagrowthhub3083  3 года назад

      The volume of diluent should be sufficient to solubalize your analyte before you proceed degradation

    • @krish_krish354
      @krish_krish354 3 года назад

      @@pharmagrowthhub3083 if suppose sample and HCl only added no other diluent added before keeping in oven.
      after taken out from oven neutralize with NaOH and make up with diluent.
      This way of doing foreced degradation right or wrong.

  • @krish_krish354
    @krish_krish354 3 года назад

    Degradation 5_20 or 5_30 in other video of yours I saw 5_30 which is correct

    • @pharmagrowthhub3083
      @pharmagrowthhub3083  3 года назад

      5-20% is more relevant and accurate, though there is no as such regulatory reference available.

    • @krish_krish354
      @krish_krish354 3 года назад

      @@pharmagrowthhub3083 thank you

    • @krish_krish354
      @krish_krish354 3 года назад

      @@pharmagrowthhub3083 what are regulatory guidelines using for a method validation. Not only ICHQ2R1 and R2. Other than