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Q&A: The Latest in PD Research 2023

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  • Опубликовано: 14 авг 2024
  • Q&A: The Latest in Parkinson's Research 2023 with Jeff Bronstein, MD, PhD, from UCLA.
    A Parkinson's Community Los Angeles (PCLA) "Let's Talk Parkinson's" online live program from July 27, 2023. www.pcla.org.
    -----------------------------------------------------------------------------------------------------------------------
    Timestamps:
    00:00 Intro
    01:42 Dr. Bronstein Intro
    02:37 What Causes Parkinson’s?
    06:12 α-Synuclein Pathology
    07:44 Vagotomy Reduces Risk of PD
    08:35 Where PD Starts
    10:04 Symptoms
    11:54 PD Process Spans Decades
    12:46 What Starts the PD Process?
    17:10 Environmental Factors
    20:47 Disease Pathways
    22:16 Promising Diagnostic Tools
    25:08 Promising Therapies
    28:46 Prothena
    30:18 GLP-1 Agonists
    31:36 Exenatide and PD
    32:01 1st Disease Modifying Therapy
    33:38 Promising Symptomatic Therapies
    36:02 Continuous Levodopa Delivery
    36:38 New UCLA Faculty Research
    38:38 Q&A
    56:29 Closing
    -----------------------------------------------------------------------------------------------------------------------
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    Parkinson's Community Los Angeles is a non-profit organization. If you enjoyed this free program, please consider donating to PCLA on our website at pcla.org/donate/.
    PCLA's online events are intended as an informational and educational resource for the Parkinson's community. Always consult with your healthcare team for medical and treatment advice. The views and opinions expressed by presenters and participants do not necessarily reflect those of PCLA. Sponsorship support does not influence PCLA's content perspective or panelist selection.
    #parkinsonsdisease #parkinsons #parkinsonsresearch #letstalkparkinsons #pcla

Комментарии • 26

  • @rosielux108
    @rosielux108 10 месяцев назад +3

    Excellent presentation. Really appreciated the detail. I’m a yoga teacher who specialises in PD. The more people can understand PD the better, and it helps people feel like they have some control and choice in the treatments and protocols they employ.
    Thank you 🙏🏽

  • @carbonejack
    @carbonejack 11 месяцев назад +5

    Extremely helpful presentation, in a way I can understand the dynamics of PD. I'm currently in the Fox Foundation PPMI research study. This video helps me understand what I have experienced over the years; constipation, loss of smell, RBD. Fast forward to today. I'm now experiencing rigidness and walking issues. I've not been officially diagnosed, but I believe it's just a matter of the time in the next step of my participation in PPMMI.

    • @Bestvidoes3078
      @Bestvidoes3078 8 месяцев назад

      Homeopathic medicine plumbum met 200

  • @monika6974
    @monika6974 10 месяцев назад +1

    Extremely helpful presentation, in a way I can understand the dynamics of PD.

  • @laggerb4680
    @laggerb4680 10 месяцев назад +2

    I wonder how I’m diagnosed with pd (tremors & tension in arm muscles, abnormal Datscan) yet not ever had constipation, reduction of smell, or continual sleep problems). I’m female 78 yrs old.

  • @user-jb6no9ty3t
    @user-jb6no9ty3t 2 месяца назад

    My husband had pd he always had a healthy diet ate alot of fish and fruit never drank alcohol or smoked so what the answer to that he died at age75 lost his swallow horrible death listener in Ireland

  • @user-re9wf1ts4x
    @user-re9wf1ts4x 10 месяцев назад +1

    What is the medication to use for parkinson dísease

  • @PaulHigginbothamSr
    @PaulHigginbothamSr 10 месяцев назад +2

    So this seems to be related to prion disease like mad cow disease. With cow prions you almost have to burn the bodies to remove the prions. What we need to develope is a good protein that takes the irregular shaped proteins and turns out correctly shaped proteins. Possibly a virus like infection that eats the misfolded protein and turns out good proteins. Hopefully we find something that removes the bad protein and does not make us permanenetly ill. 57:47

  • @FatherSebastiaan
    @FatherSebastiaan 11 месяцев назад +1

    what about Vaxxinity's new UB312?

  • @normanrubenzer
    @normanrubenzer 9 месяцев назад

    im shocked that the red light therapy is all hype!!! there are companys like symbx in australia having suscess and in canada.. so my wife is thinking about the duopa pump but would prefer the small pump verses the big one.please let us know when the fda approves the new pumps

  • @peter572
    @peter572 10 месяцев назад +1

    Can photo-bio-modulation therapy halt or improve PD symptoms?

    • @deborahd.7281
      @deborahd.7281 9 месяцев назад

      They keep developing more and more expensive drugs that they can patent that may not be any better than previously developed drugs. Photobiomodulation is used in New Zealand, Australia, and Europe. There are several devices ranging from a few hundred dollars and higher that have shown significant benefits. It seems that most neurologists in the United States will say, "oh, not enough research on that".
      These drugs have major negative side effects, photobiomodulation generally has beneficial side effects.

  • @gailcline9023
    @gailcline9023 10 месяцев назад

    27:39 27:41

  • @kevinfitzgerald7474
    @kevinfitzgerald7474 9 месяцев назад +3

    What's the research. You found the cause. It's not genetic.

    • @ivarsmednis
      @ivarsmednis 8 месяцев назад

      I 2:03 ii😅jiiii

  • @lillianateran3666
    @lillianateran3666 10 месяцев назад +1

    por favor traducir en español

    • @roscoro
      @roscoro 10 месяцев назад +1

      Utiliza el botón de configuración y te dará traducir como una opción y lo pones en español

  • @carmengloriadelgado9102
    @carmengloriadelgado9102 Год назад

    Hola, estoy muy interesada en saber si podían dar traducción en español de lo expuesto?, muchas gracias, un saludo

    • @ParkinsonsCommunityLosAngeles
      @ParkinsonsCommunityLosAngeles  11 месяцев назад +1

      Hola, deberías poder utilizar las herramientas de RUclips para traducir esta charla al español. Gracias por ver

  • @rexeverything6249
    @rexeverything6249 11 месяцев назад +2

    Abel kinnaese inhibitors are whats needed inhibikase ikt-148009 is the one second phase trials now

  • @erinoreilly4496
    @erinoreilly4496 10 месяцев назад

    Since PD has a strong gut connection, I wonder if not being breastfed is a risk factor for PD?

    • @stephendunn2733
      @stephendunn2733 9 месяцев назад

      For a different reason I have wondered the same. The number with PD in Australia has doubled since 2015. Median age of diagnosis of 61 aligns with the huge switch in Australia to formula feeding during the fifties as it was viewed as being more socially acceptable.

  • @danielprose5878
    @danielprose5878 11 месяцев назад +1

    Removing alpha synuclein from this area was not affective and showed no relief or stopped the condition. Sadly !

    • @rexeverything6249
      @rexeverything6249 11 месяцев назад

      Inhibikase therapeuticshas it worked out with there drug ikd-148009