Paliperidone (Invega): A comprehensive review of an atypical antipsychotic
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- Опубликовано: 2 июн 2024
- In this video, we discuss the atypical antipsychotic medication, paliperidone or Invega. Risperdal is the parent drug of paliperidone (Invega) so if you missed that video, make sure to check it out as they are very similar. The main difference is that paliperidone (Invega) tends to be more tolerated than Risperdal and paliperidone (Invega) is given once a day as an extended-release tablet. Paliperidone (Invega) also has 3 different long-acting injections: Invega Sustenna- monthly, Invega Trinza- every 3 months, and Invega Hafyera- every 6 months.
Intro: 00:00
What is paliperidone (Invega)? 00:55
What is paliperidone used for? 03:41
How long does paliperidone take to work? 04:25
Is paliperidone addicting? 05:25
Side effects of paliperidone 06:30
Drug interactions related to paliperidone 10:57
Final thoughts on paliperidone 12:31
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Patient Resource: medlineplus.gov/druginfo/meds...
References:
Invega FDA Label (2010). Retrieved from www.accessdata.fda.gov/drugsa...
Stahl, S. M., Grady, M. M., & Muntner, N. (2021). Stahl's essential psychopharmacology: Neuroscientific basis and practical applications. Cambridge University Press.
Stahl,S. (2017). Stahl’s Essential Psychopharmacology: Prescriber’s Guide, 6th Ed. Cambridge University Press.
UptoDate. (2022). Paliperidone: Drug information. Retrieved from www-uptodate-com.libproxy.eku...
Disclaimer: All of the information on this channel is for educational purposes only and not intended to be specific/personal medical advice or substitute for diagnosis and treatment of any conditions discussed herein. Furthermore, watching these videos or getting answers to comments/questions, does not establish a provider-patient relationship. Please consult with your own health care provider for proper diagnosis and treatment.
Do a segment on the horrifying side effects of this drug as well, the reality of this drug.
Makes my heart race makes me shaky and makes me not sleep for until I stop taking it and take olanzapine again no orgasm crazy as hell
Yeah I'm one of the unlucky ones with this drug and it was scary! Extreme sleepiness (14 hrs sleep and still tired) along with the worst tachycardia I've experienced( my heart rate doubled to a resting 120). I'm glad I stopped it though my doctor was super aggro about it.
I can testity. My life went from good to hellish
Tell us more
What did you guys do instead
Invega sustena is poison jhonson and jhonson are satan
I had to use this drug for a year because of a drug induced psychosis and it was the worst year of my life because i became zombie like and I had to deal with the breakup of my ex at the same time.
I’m so happy I’m over this now and back to my old creative and happy me !
Bro this is like me right now
@@user-wc5vd5tl1q I’m sorry about that, just always remember it’s going to pass and stay hopeful about the future 🙏
How did you get off of it?
Lucky you😢 my mom has never been the same I don’t know how to help her 😭😭
Did the psychosis go away permanently?
this medication has turned my once vibrant funny and outgoing daughter into a recluse in a zombie like state. she barely seeks she stares into space and moves in slow motion. while sh no longer has manic hyper episodes she is now on the opposite end of the spectrum . i must say its a bit unnerving seeing this hallowed version of my daughter but i do my best to support her. i love y adult daughter and want the best care for her.
What did you end up doing. Meds can be reduced very slowly
I see a lot of people had bad experiences with invega. however invega sustena saved my life. I have schizoaffective disorder and would be in and out of hospital without this medication. The difference is mind boggling... I feel like the reason for bad experiences come down to irresponsible use of the drug. This REALLY isnt for depression or even for anything else than schizophrenia.
I'm glad you found a treatment that works well for you!
I agree with your comment! This drug was the best one out of the 3 or 4 that I tried. I felt like I was actually myself, no brain fog or heaviness! The reason I'm on RUclips researching is because I've been on this drug for exactly 10 years and I'm wondering how safe it is long term. Do you know anything about that? I tried to go off of my med in 2018 but it was terrifying...I just wonder if it would balance out or if I'm permanently "schizoaffective". Thanks!
Hi thank you so much for commenting! I know that in comparisons to other antipsychotics Invega is one of the most safe medications long term. There is a lower risk of akathisia (or restlessnesss). Also, of other comorbid conditions like metabolic syndrome. I highly suggest you stay on this medication over any other antipsychotic. Have a blessed day.@@liannelessard3609
Thanks for answering my questions have a great day 😊
You are very welcome. You have a great day as well! 😊
Terrific! My students here in Japan are dealing with Xeplion (the name for Paliperidone in Japan) and this video is a clear, watchable overview of the drug. Thanks so much!
Exceptional channel! Thank you🙏
Thanks for watching.
Excelent presentations
Thank you so much for these videos. I just moved the mental health unit at my hospital, and these are really helping
I'm glad you find them helpful. Thanks for watching!
Thank you for making these videos! They're very helpful to me.
I'm watching these videos trying to emotionally prepare myself for the idea of taking medications. The music underlaying this video, with the minor key and EDM beat, feels haunting to me. This is counter-intuitive for me, since I want to become more relaxed about needing help. In the future, if the background music could all be happy or calming, that would be great! No pressure.
Thanks for the insight.
Thank you for your wonderful videos.
You're welcome!
I remember taking that medication at a young age. I hated it. I had abnormal eye movements and and rapid heart beating. My eyes were literally stuck in the ceiling and all my doctor did was increase the dose. Every time my mom kept making me take it she would get mad when my eyes are stuck up my skull. I also had a hard time sleeping because my fucking eyes won't close because of the increased dose. It was frustrating.
We're you not ever given a prescription for a drug that counteracts those side effects? I can't think of the name right this sec. It's been around for years and years. It's chemically similar to benadryl and benadryl can be used as a substitute if need be.
@@carolethorn3211 I was given concerta but that became kind of an addiction
Recovery?
Very good reminder of SE..
been the worst if all APs for me. wasn’t even on injections, only oral. made me infertile
was forced to take risperdal then went on to have 4 shots of paliperidone. i had my last one was feburary, i didnt have schizophrenia or anything, i was in hospital due my eating disorder. i am worried its done permanent brain damage. i have severe anhedonia, lack of motivation , slow thinking cant concentrate, no periods , sucidal and insomia. its now june and no improvement, i have no dopamine or serotonin . i am doomed and going to be like this forever
get some stimulants
how is that going to help
I shared this link to 💡 🌱 family and friends that I plan on contacting throughout my life.
Can someone please tell me how I can get off this drug I feel like I don't need these drugs anymore I have no life on this drug?
Can you please do a video on Geodon (ziprasidone)? Thank you! :)
Thank you very m 13:27 uch can you explain the drug cogentin
Does it affect the memory in any single shape or form?
Thanks for the video!
It can cause brain fog in some patients.
@They have NO AUTHORITY I read that it reduces the amount of Glial Cells and can't be repaired nor regenerated. Have you looked into it? Also, is there any chance based in your case that is there possibility which your memory might increase cognitive function..etc.
My son was just injected with a 1 month shot even though he has akathisia, constipation with some blood in his stools, agitation, and sexual dysfunction after just 1 week on the week injection. Does this make sense that they injected him for another month with these side effects? Hopefully, there will be no more side effects.
Discuss this with your provider. It may be that he reacted to the loading dose and as it tapers off in the body those effects will diminish. If not, be your son's advocate and speak up!
@@LevelheadedMind I am trying to be his advocate, but they went ahead and injected him even though I was trying to tell the nurses about the effects of the meds and that they have to change meds but they went ahead anyways. So is it normal for a loading dose to have these effects in the beginning and diminish afterwards? They put him on Congentin and a few other meds now. the less meds the better in my opinion cause now he has more meds to taper off of. this sucks!
@B Charron why are you poisoning your child you crazy. It's illegal to medicate anyone against their will.
Isn't that bad of a drug it seems to deal with pre-cope depression really well and plants a great seed? From a long-time user.
No, the seed is subpar at best
@@Premaire what do you mean by that?
Pls Radio dispatch me asap...
It does help with depression but the injections are god awful a few days following. More of a neuroleptic imo
Can you make a video about Perseris?
Here is the video I made about risperidone, which is the generic name for perseris ruclips.net/video/RrGFc3QaQrI/видео.htmlsi=W9RY2-Tih2Z_Q92c
This drug saved my life
Yeah. With a period.
Well you don't have a life in the first place then.
The injections truly helped my family members. Love this medication!
Mine too
I'm very happy for you and for everyone it worked on but you seem to be in the minority.
Do you have a video done on ketamine for mood disorders?
Not yet, but will consider it.
@@LevelheadedMind that would be awesome. I just did my first consultation and am about to start infusions for treatment resistant depression
@@LevelheadedMind is invega good for major depression I'm talking to my psychiatrist about this tomorrow
And number EIGHT...How to get off of it safely?
Depending on how long you have been on it, it is best to taper off slowly, discuss with your provider.
This drug ruined my life
This "drug" makes my heart beat out my chest sometimes. You also sleep for way too long and feel no emotion when taking this. The ones who force this on people are 😈
So I’ve been using invega sustena injections for 9 months and I’ve been off them for 2 months now but whenever I drink alcohol I really can’t get drunk I only feel numb and I heard from some people that this is permanent so is that true ?
More mind destroying poison...
Reinhold Von Treffencaunbowz, MBBS, PhD
People complain if someone farts to the left
It's not a anti psychotic, it's a anti psychosis drug,
If pooling serotonin in the mind cause greatest bodily use out of it it's be psychosis causing if serotonin was magnify, the reality it's not a anti psychotic control mechanism, psychotic emotion is anger with flight mechanism or sadness, that's caused by low uptake of serotonin.
People with depression can't have happy go lucky high serotonin psychosis emotion delusion , depressed people get psychotic depression, in the Parkinson's an tardive dyskinesia people simply didn't have high serotonin an dopamine schizophrenia
Drug induced psychosis isn't predisposition to psychosis, that's predisposition to psychotic emotion, people with normal serotonin have a normal balance of psychotic an psychosis emotion, depression is psychotic emotion switched on all the time that paliperidone isn't a control mechanism of
In reality the only control mechanism, the only true anti psychotic is something like marijuana that raise serotonin in the depressed an raise dopamine in the Parkinson's case, that mild regular use stop psychotic being switched on the restore a normal balance of psychotic an psychosis emotion
It's a mistake people with normal serotonin uptake make in thinking psychotic emotion is associated with psychosis emotion because they got drunk before an it was a psychotic or psychosis outcome drinking is induced bipolar, that people with depression smoking marijuana that isn't the reason they are psychotic,they are smoking weed in response to psychotic emotion because it's traumatic completely sober
How does paliperidone be a control mechanism of angry or sad psychotic emotion, it's simply not a anti psychotic, it's an antagonist of psychotic emotion in people with psychosis switched on from predisposition to psychosis
Disturbing and horrible side effects
It led to my father's death.
@@carolethorn3211 wow, I am so so sorry for your lost. My heart and prayers goes out to you and the rest of the family.
Why in the world would the medical association invent and use something like this as a medication, it blows my mind. The medical department who allows this to go on, you guys are absolute disgrace for human life. Should be shamed of yourself, you low life’s. Plus I make no apologies of my remarks.
@@shailendranaidu5094 thank you for the supportive comment. The drug was used "off label" - in other words, used for a purpose its not approved for by the FDA. It happens ALL OF THE TIME. (with this drug and others very similar, it is common practice - though unethical - to use as a form of "chemical restraint", mostly in elderly people even though the literature provided with the drug clearly states "WARNING" : Not for use on patients over 65.)
Tell me please? I want to hear from people who have been on it. My Dr wants to put me on it
@@carolethorn3211 so sad that such an unethical and irresponsible practices are taking place in our so called health care system.
Please speak up and bring it to attention of the higher authorities in the medical department. For the benefit of the community and more importantly closer for you and the family.
May God bless and keep you and family.
Horrible medication, worst of all antipsychotics . I had a seizure on it
ITS FUCKING RUINED MY LIFE
We are living in end times. Imam Mahdi is coming the savior
This med causes me suffocation, NOT medicine: manic depressive
Worst med ever!!!! Nightmare 24/7