At 5:21, you mention that a large MSA provides sufficient information to do accurate structure prediction (doesn't need template data). What information is supplements template data when an MSA is large?
Thanks for this very useful webinar! Is it possible to use this material for teaching? Specifically, the description of the different parts of AF are excellent, but the slides say "private and confidential". Thanks!
I have two peptides with 17 residues each, one is head to tail cyclic peptide and the other is stapled peptide. Does alphafold2 work with chemically modified peptides?
Hey folks, beautiful session! I have a question where I ran a local version of the alphafold and want to get the 3D structure, but cannot produce anything. Is there a certain program I should be using to render the images?
I prefer to sphere pack all those with a spherical formula by implicit equation I know it's not practical to morph the manifolds analytical but it's a piece of cake and a beauty of mathematics can be applied at micro level but applying some 3d morphing computational algorithms which have minimal computational time but a symbolic one would be a work of beauty to unfold these protein cells
Nice, complexes hack is beautiful indeed. I hope you will do > 2700 human proteins in Molstar viewer, after all Molstar can do even insane Viruses, no problem.
At 5:21, you mention that a large MSA provides sufficient information to do accurate structure prediction (doesn't need template data). What information is supplements template data when an MSA is large?
Does anyone know how to access PAE metrics when running inferences on a local install of AlphaFold?
Check the FAQ section of the AlphaFold database.
720p please. sorry but i'm old...my vision's blurry...
Amazing work! Thanks for sharing
Thanks for this very useful webinar! Is it possible to use this material for teaching? Specifically, the description of the different parts of AF are excellent, but the slides say "private and confidential". Thanks!
I cant see what is on the screen.
480p res explaining how they’ve used computers to fold proteins.
fantastic video lesson!!
Thanks for uploading
Do u have a course for Alphafold2&Ebi coding?, or bioinformatics in general?
I have two peptides with 17 residues each, one is head to tail cyclic peptide and the other is stapled peptide. Does alphafold2 work with chemically modified peptides?
No.
@@SerioussoccerfanYT Thanks
Hey folks, beautiful session!
I have a question where I ran a local version of the alphafold and want to get the 3D structure, but cannot produce anything.
Is there a certain program I should be using to render the images?
use pymol
I prefer to sphere pack all those with a spherical formula by implicit equation I know it's not practical to morph the manifolds analytical but it's a piece of cake and a beauty of mathematics can be applied at micro level but applying some 3d morphing computational algorithms which have minimal computational time but a symbolic one would be a work of beauty to unfold these protein cells
Nice, complexes hack is beautiful indeed. I hope you will do > 2700 human proteins in Molstar viewer, after all Molstar can do even insane Viruses, no problem.
So helpful
Upload the video in 720p resolution. Otherwise delete it...
Lol
how about: go solve your own structures
The original is in 1080p. Somebody still uses 720p?
@@lolerie Setting on this video gives resolutions up to 480p only.
@@MolecularArts and on original there is 1080p which you can download with youtube-dl.
420th like