Protein Protein Interactions String Cytoscape

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  • Опубликовано: 24 ноя 2024

Комментарии • 28

  • @Biomeducated
    @Biomeducated 3 года назад +1

    0:00 Input of 90 genes into STRING database website
    1:18 Network stats and expansion of the nodes on the STRING website
    5:25 Transfer of the network to CytoScape
    8:15 Network analyzer plugin and analysis
    15:52 Network style editing
    Great tutorial! Thank you BB!

    • @jaannawaz2007
      @jaannawaz2007  3 года назад +2

      Thanks for sharing!

    • @Biomeducated
      @Biomeducated 3 года назад

      @@jaannawaz2007 No, thank YOU for sharing! ;)

  • @yusufceylan104
    @yusufceylan104 2 года назад +2

    Hi! Thank you for this valuable video. I did not understand something, you uploaded 90 sequences and you got 74 nodes, why did you try to increase the number of nodes above 180?

  • @jamalkhan5752
    @jamalkhan5752 4 года назад +2

    hi, how to identify upregulated and downregulated genes in the network?

  • @jyotibala102
    @jyotibala102 3 года назад +1

    Great video...Thankyou for sharing

  • @adrianalopez6035
    @adrianalopez6035 Год назад

    Thank you so much :')

  • @painpp
    @painpp 2 года назад

    hello nice video, may i ask a question. I have some proteins that interact with each other, i just want to show the interaction between these proteins, please let me know how i can represent the same.

  • @caitlingibbons2246
    @caitlingibbons2246 3 года назад

    Hi.
    Thank you for uploading these videos. I was hoping you could tell me how you obtained the list of up and down regulated genes. Did you use R with Bioconductor along with one, or more, GSE files from the Gene Expression Omnibus? I m working on a class project and I was hoping you could help me. Thank you.

  • @VibewithSharonAlexander
    @VibewithSharonAlexander 2 года назад

    Well explained

  • @avanimahadik8551
    @avanimahadik8551 4 года назад +1

    in the string database why do we need to expand the network? Is it we always expand the network or there is some criteria used? If any such criteria is used can u please tell about that?

    • @fengtang6433
      @fengtang6433 2 года назад

      That's what I also want to ask. So many unmeaningful operations. I wasted 20 mins here.

  • @johirislam8174
    @johirislam8174 3 года назад

    Hi,I want to visualize my PPI network into cytoscape.But my ppI node are 661 and edges are 680 and seeds are 15.So i feel problem of visualizing it into cytoscape.Because of huge number of nodes and edges. So how can i visualize this .I mean to say I want to know the way that can visualize all the interacted nodes clearly. Clearly means all the lebels are being clearly watched in manuscript.

  • @shtaahshtaah8262
    @shtaahshtaah8262 3 года назад

    I have dataset how can find correlation with gene expression for detecting Alzheimer's disease.plz answer

  • @takimsarker929
    @takimsarker929 3 года назад

    nice video. I think the sound quality should be more clear.

    • @jaannawaz2007
      @jaannawaz2007  3 года назад +1

      its an old video .. now u can see more quality in my videos...

  • @manendra3650
    @manendra3650 3 года назад

    You are concentrating on how to plot graphs but please update us how to understand the data....

  • @mominashanwaz
    @mominashanwaz 4 года назад +1

    how to analyze the data in the table?

    • @jaannawaz2007
      @jaannawaz2007  4 года назад

      Hi... this video is just demo of how to use Cytoscape... and it covered briefly on the degree of interactions in between the protein-protein. If u want to analyze whole statistics of the table u have to go through the following link manual.cytoscape.org/en/stable/Network_Analyzer.html

  • @jyotibala102
    @jyotibala102 3 года назад

    Can you plz upload some online structure prediction tools for DNA 3D structure prediction.

    • @jaannawaz2007
      @jaannawaz2007  3 года назад +1

      Yes.. Soon

    • @jyotibala102
      @jyotibala102 3 года назад

      @@jaannawaz2007
      Thankyou, we find multiple option for protein through limited tools for 3D nucleic acid....

  • @aditikonar2411
    @aditikonar2411 5 лет назад

    I have a set of structurally similar proteins ( that i got in DALI search) so can I study their degree of relatedness this way? Or i also need the substrate with which those proteins interact?

    • @jaannawaz2007
      @jaannawaz2007  5 лет назад +1

      I think Dali will give you known protein structure (Protein Data Bank) results by comparing your protein Query sequence. If you have a group of proteins, yes you can check Protein-protein interactions. The results will elucidate you how protein are interacted together based on proteins Co-occurrence, Co-Expression, Experiments, Databases, Text mining, physical interactions, gene fusion, neighbour genes

    • @aditikonar2411
      @aditikonar2411 5 лет назад

      @@jaannawaz2007 thank you so much

  • @kingrock04
    @kingrock04 4 года назад

    Thanks for the video it's great.
    But How do you analyze the data in the table? and how is the interpretation and application?

    • @jaannawaz2007
      @jaannawaz2007  4 года назад

      If u want to analyze whole statistics of the table u have to go through the following link manual.cytoscape.org/en/stable/Network_Analyzer.html