What about the prokaryotes ? Do they start the transcription from Pribnow box @ -10 sequence (coz as far as I know, it should be recognised by sigma factor of holoenzyme, isn't it) ? Or start from the Upstream promoter element @ -60 sequence??? I think I'm kinda confused here....😫
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enhancers could be upstream-downstream and also in rare cases inside the gene body.As enhancer like cis sequences influence a site which is far away from the promoter it really matter how enhancers are interacting with the promoter in a 3d chromatin landscape.
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What about the prokaryotes ? Do they start the transcription from Pribnow box @ -10 sequence (coz as far as I know, it should be recognised by sigma factor of holoenzyme, isn't it) ? Or start from the Upstream promoter element @ -60 sequence??? I think I'm kinda confused here....😫
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Very helpful, Thank you!
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What is the position of enhancers from start site upstream or downstream?
enhancers could be upstream-downstream and also in rare cases inside the gene body.As enhancer like cis sequences influence a site which is far away from the promoter it really matter how enhancers are interacting with the promoter in a 3d chromatin landscape.
Thank you very much doctor
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good
Really glad to know it was useful. Please follow my instagram page and facebook page. Please share my youtube channel link with your friends and help me to reach big audiance