Hemoglobin moves O2 and CO2 | Human anatomy and physiology | Health & Medicine | Khan Academy
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- Опубликовано: 14 окт 2024
- Learn the two ways that oxygen moves from the lungs to the tissues, and the three ways that carbon dioxide returns from the tissues to the lungs. Rishi is a pediatric infectious disease physician and works at Khan Academy. Created by Rishi Desai.
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You explained this so beautifully it makes me want to cry.... I've been freaking out about not understanding this, but now I do, so thank you!!!!!
Absolutely! I will get this done soon...
Why can't you just reply to the user instead?
@@9-volt247 11 years later💀
I don't know who did this video but, his presentation on this topic is one of the best I've heard. Good job.
THANK U, Khan Academy! Ready for my medicine exam!!
Hi, I'm Korean. I've been looking for a lot of information and videos related to this topic. But this video really explains the topic well. Thank you very much. This video is just touching!
khan academy.. those guys are heroes :D
Check out the video on the Bohr effect and Haldane effect. =)
Another awesome video! I love the way you explain things...way more clear to me than in my textbook. Thanks!
Thank you so much for all of your videos, you make everything so much easier to learn and understand !!!
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lola pa said it before me: you have no idea how helpful your videos are!!! I wish somebody could help you sometime, how you helped so many of us!
I feel the same way. These videos summate a 55 minute lecture into 15 minutes of clear, succinct explanations. Thank you so much.
a classic lucid explanation!✨️ Thankyou Khan academy!!
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I want to thank you so much for making it much easier to understand, you explain so much better than my teacher. Much LOVE!!
The video does explain the concept in a very detailed but concise manner.... The point about the chloride shift (Hamburger Phenomenon) could also have been included.....
This clarified many of my doubts. Thanks Khan Academy!!
very very good and useful , THANKS!
Khan, how can I give you feedback? Many videos have minor errors, e.g.
H+ and CO2 do not bind to the same site as O2, so it doesn’t kick O2 off, but it binds somewhere else and lowers the O2 affinity of Hb.
Also equations reverse in the lung because CO2 is being lowered, i.e. as it comes off of Hb, it lowers Hbs affinity to O2. Not that O2 coming aboard kicks off CO2.
so the O2 does not get kicked out of the car...there is simply less room in the car for O2?
Incorrect analogy
More like.. The more country kids (CO2) show up to the drive-in and hop in their friends' trucks (amino binding site), the less the rockers (O2) want to chill at the drive-in, so they jump out of their Nova's (heme binding site) and peace out. The more that leave, the more cowboys show up and visa versa, depending which side of town drive-in they go to (lungs vs. thigh/glutes etc).
Thank you for this! As I was listening it didn't seem quite right...
Seriously you are AMAZING , you have no idea how helpfull your videos are .
Thankkkk Youuuu Soooo Mucchhhhhh !!
Awesome video, thanks alot!
In my text book it says that O2 binds with the heme group of the hemoglobin molecule and CO2 binds with the amino acids in the globin part of the hemoglobin molecule, therefore o2 and co2 do NOT compete.
Thank you so much! Saved my life!
This is how Khanacademy should be. I didn't have to play it on 2x speed this time.
I did
But errors
Thank you, I am now getting it.
Dr RISHI thanks a lot bro
The best explanation :)) I feel more confident about the mcat now
what app are you using? great vid
thank you for uploading this and for the effort
fantastic, beautiful, brilliant explaining!
Thank you khan academy ready for my A&P exam
Thanks for the videos, really well explained. What program are you using for this videos?
Very helpful.. Thanks!
Nice, concise
Thank you! You explained it so well :)
My teacher was harsh and put this on a question sheet for year 7s. This really helped. Thank you !
Again ... than k you so much for this great video ... your the master! :-)
Thank you so much.
wow, now i got it...very helpful...thank you so much..so easy to understand...:)
Excellent work guys!
beautifully explained
Life saver!
Thank you.
Very nice videos. Hav u guys made any videos on ventilation perfusion mismatch in lungs especially discussing increased dead space due to thrombus in pulmonary artery. Can't understand.
very useful thx
I learned this in class!..... But that took 2 months and this took 14 minutes
That's because you worth that one month. It always feels like we don't know anything. But in reality our mind collects those little information that are easy to learn about that. That made us easy to learn it later. And it felt like we're reading it for the first time. But when we see all those things twice. We started thinking like yeah.. I think i know a bit about it.. But it just slipped off my head.. My way of reading something i 1st catches the things that are easy to memories.. And repeat them..and while repeating as revision i do recall those words or lines that i don't understand. And then i work on it. If it seems intresting as well as important. I just do not force my mind to attain 90% of concentration at each topic. But after a large break. I first pick up all those hard points. & lastly reexplain everything that i had learnt.
Awsome! Thank you so much!
this was so helpful! thank-you
I've got a question, the protons formed in the carbaminohemoglobin are they still binding to another molecules of hemoglobin or they're still bind with the COO-?
Great job bro..........waiting for videos
Thanks. Great explanation
thank you is very interesting
really helpful specially when i am going to sit my as exam very soon and my teachers are still watching youtube during lesson
thanks soooo much! awesome
very well explained ! :)
Eventhough English isnt my mothertounge I could follow you easily.
Helped me a lot
Very good video khan acaddmy
Thank you
loved the vid by the way
Extremely helpful video ❤️
the best vedio in you tube
good job
you're the best
Thank you very much
this is great!
I have a slightly off-track question for you about SpO2 vs SaO2 cuz i'm having trouble finding an answer: apparently both measurements can be read by a pulse oxymeter. However, is it true that SaO2 can only be read by blood sampling through an i-STAT reading. I'm a little confused.
The Blueprint of Life and Wellness
very helpful
Does the blood from the thigh not go to the heart and then the pulmonary artery where it is transported to the lungs?
thanks !
Nyc nd helpful videos
actually.....great vid 😍😍
Oh my god after two weeks I finally get it!!!!
You´re amazing, I finally get it now :)
When protons competed for hb oxygen lost it ( At the thigh cells )and when oxygen competed for it, protons lost it ( Alveoli ). How is that possible and why ? Please explain. That curiosity burns me from inside.
Can hemoglobin bind to oxygen and carbon dioxide simultaneously?
Yes man
What happens with the chloride? HCO3 wont get out by himself, it will be an exchange with Cl. What about that?
Thank youuuuu!
thank you so much! you're awesome :)
very well explained thanks so much :)
Rishi, I have a question: My anatomy textbook says that C02 doesn't bind to hemoglobin in the same area as O2 (the heme group). So, is it correct to say that CO2 "bumps off" O2 when it encounters oxyhemoglobin in systemic circulation?
I think you are mistaken when CO2 binds with oxyhemoglobin, it forms just carboxylhemoglobin and O2, no H+ protons
The reaction frees a hydrogen and the T state is stabilized by its uptake due to dimer/dimer ionic interactions
Yeah
Damn this guy is insane. What a great teacher
Ready for my A&P II exam.
I might have to watch this video more 5 times
Where can i take a chemistry class as refresher ? So i can better understand human antomy D: im going to be RT but im WEAK in sience
Im having trouble understanding the bicarb, pCO2 system for clin chem can someone please explain?
In respiratory acidosis, pCO2 is increased. So the compensatory effect is increased HCO3-. All of my notes say that kidneys retain bicarb. How does retention of bicarb increase bicarb?
I'm stumped on that one too...if you've found out please tell me :)
Audio tech comment only - Your voice level seems to be a bit too high for the system ie. The meter is in the red ; ) - and distorting. Respectfully.
hey can you do a video on the Intrinsic and Extrinsic Pathways of Coagulation?? :)
you elaborate more on co2 and h20
😅. KHAN. ACADEMY Medicine. ". Rules. In. My. World 🌎🌍
Sir how many molecules of co2 carried out by the hemoglobin. ?
when the O2 competes for hB and forces the release of HCo3 and H+ in the RBC is that the Bohr effect? and when the H+ competes for hB, releasing O2, is that the Haldane effect?
wow
Thank you, but just one problem, you said : CO2 + HbO2-----> Hb.coo- + O2 + (H+) from where is coming this H pro to?? and as well the negative charge on Hb.COO- ??
Thanks
The proton comes from one of the oxygen atoms. If we remove a proton, the atom becomes negative. I hope this answers both of your questions
Yes, it does, thanks
you are absolutely amazing :)
"Hemoglobin" is Spelt "HAEMOGLOBIN" :O
I didn't think H+ competed with oxygen because they bind at different sites on the Hemoglobin. Where does the H+ ions bind to on the hemoglobin? to the histidine? lysine? propionate group? I believe it may be the c-terminal histidine group but I am not sure. Could someone clarify?
why oxygen binds to iron if iron 2+ and already binded to four nitrogens and one globin. How oxygen finds place in this complex substance?
The Seahawks should of run the ball
CO2 splits up in CO2- and H+. Then CO2- combines with Hb and H+ is released.
i hope i am right.
damn will i learn about proteins and acids in anatomy and phyisiology?
same question i do have
Aah...blood. This is what I like other than diabetes or the government crap.
Yeah, Nauroz Syed is lying. I don't understand why.
Not only Syed is a doctor, she is also a politician.