PSW 2473 The "All of Us" Research Program | Andrea Ramirez

Lecture Starts at 11:19
www.pswscience.org
PSW #2,473
March 3, 2023
The "All of Us" Research Program: NIH's Plan to Build a Million Person Health Metric Database
Andrea Ramirez
Chief Data Officer
National Institutes of Health
The All of Us Research Program is collecting health data from at least a million people to advance precision medicine research and fuel new insights into human health. The lecture will discuss the ways the program is looking to accelerate medical research and advance health equity through its robust research ecosystem, as well as the opportunities for researchers to begin using the rich dataset.
The platform currently supports more than 4,200 registered researchers with more than 3,600 active projects. Information about each workspace’s research purpose and team are publicly available. De-identified, row-level phenotypic data has been available since May 2020 through the Workbench’s Registered Tier, and a new Controlled Tier includes data from nearly 100,000 whole genome sequences from All of Us participants, alongside other data types.
The Researcher Workbench now includes data from more than 372,000 participants. Inclusion of data from all of society’s diverse ethnic and genetic backgrounds is essential to the program serving its broad goals. Thus, far nearly 80% of participants identify with groups historically underrepresented in medical research, including 45% who identify with a racial or ethnic minority group.
The promise of medical research will only be made possible through a pervasive and unyielding commitment to inclusion that provides an opportunity to study the vast diversity of human experience. By building this health research resource and making it broadly available and accessible to the research community, All of Us is looking to change the paradigm of health research so that it is more effective for everyone.
Andrea Ramirez is the chief data officer of the US National Institutes of Health’s (NIH) “All of Us Research Program.” In addition to her work with All of Us, Andrea maintains a clinical practice in pharmacogenomics, atypical diabetes, and general endocrinology.
Before becoming the Chief Data Officer she served as senior advisor to the Chief Executive Officer of the All of Us Research Program. Before joining NIH, Andrea was a physician and scientist at Vanderbilt University Medical Center studying the genomics of metabolic disorders and precision diabetes care, where she also led the data science team at the All of Us Data and Research Center.
Andrea’s work has been funded by the Albert Schweitzer Fellowship, the Sarnoff Cardiovascular Research Foundation, and through several NIH awards.
Andrea earned a BS at North Carolina State University, and an MD at Duke University. She completed internal medicine and clinical pharmacology training at Vanderbilt University Medical Center and endocrinology, diabetes, and metabolism at NIH.
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