SS diagnosis depends on both test results and clinical findings. Is the SS diagnosis dependent on +Ro and +La? Early SS sufferers may have a +Early SS Panel and -Ro and -La: does that mean you do nothing as far as rx because Ro and La are negative? Absolutely not! They have SS and need tx to slow the progression. Studies have found that a % of SS patients never turn +Ro and +La but they have long standing symptoms (ie 10yrs+). Also SS patients don’t necessarily have to have a second AI disorder such as RA or SLE. It may manifest down the road but in the meantime they have SS and need tx. This “criteria” as it stands hinders a proper dx and therefor tx of many people with SS. I agree other things should be ruled out but symptoms+earlySS Panel+lymphocytic infiltration = SS. Lastly, what is the significance of having an ANA of 1:320 to dx SS? Anything above 1:80 is positive. Furthermore, the ANA number is not an indicator of severity of disease. The number can fluctuate and usually patients aren’t given the ANA multiple times. Once it’s positive, it’s positive. Just some issues to think about regarding SS. Diagnosis needs to happen as early as possible so the patient can receive tx ASAP. SS is just as serious a disorder as SLE and is too often not dx in a timely manner. Good video😊
Your way of teaching is fun as well as amazing I love reading biology more because of you and your videos which clears all my doubts can u please make video on breathing and exchange of gases (class 11) & neural controls and coordination as well😕
Periodontal doesn't mean between the teeth. The periodontal tissues are the ones "around" (hence "peri-") the tooth, which includes the gingiva, the cementum, the periodontal ligament and the alveolar bone. The periodontal diseases are basically gingivitis and periodontitis.
Trying to get my rheumatologist to get this lip biopsy going. I have all of the above! No one wants to do it- I wonder why? Thank you for the videos- very helpful
I loved the video! I wonder if I might have SS. I have 47XXY Klinefelter's Syndrome and I have learned that there is a prevalence of KS in men with SS. I have chronic dry mouth, eyes and nose and am currently experiencing swollen fingers.... inflammatory arthritis perhaps?!
Thank you so much!! I have a rheumatology exam in a couple of days and your videos are great for revision of the key concepts!! If someone else is tone deaf like myself and the Anti-Ro/La thing didn't stick, I can tell them apart by remembering "Black Arrow" La/SS-B: BLack Ro/SS-A: ArRow
@@MedicosisPerfectionalis You really doing amazing job you making medicine specially Internal looks like a joke while our teachers make it boring like hell and difficult to digest I will recommend all my medics teamMates
If a lip biopsy test is negative in someone with anti-ssa who has no disease syndrome, then what disease can trigger this antibody? Is it possible for someone with anti ssa not to get autoimmune disease?
He said it already that SSA is not specific only for SS. Which means it can be caused by other autoimmune diseases like RA,SLE,Myositis,sarcoidosis and others. Hence the need for differetial diagnosis .
@@bughesamiombu2909 What can trigger this if there is no autoimmune diseases? Could helicobacteria in the stomach cause this? Can antibodies change in the next blood test?
@@bughesamiombu2909 I had dryness in my eyes as a result of clogged tear glands, my ophthalmologist said I was schorgen from the blood test. However, the rheumatology doctor could not diagnose because the salivary gland biopsy was negative. The rheumatologist said that the problem I had with the eye was from using the computer excessively. However, he said that there is a high risk of contracting this disease in the future. Some doctors said that the antibody may be positive due to the infection in my blood. They asked me to repeat the blood test periodically. In the articles I reviewed, it was explained that antibodies first appeared and then the disease appeared. Is this true?
@@fatihe.1338 Now I get the full picture . Your ophthalmologist did a good job referring you to a rheumatologists with the positive test result for Schogren. However, the rheumatologists can't diagnose you with Schogren on the basis of one positive laboratory test result. Plus in addition to that , lip biopsy came out negative . Not enough criteria to make a diagnose . There is a need for a differential diagnosis inorder to exclude the possibility of other autoimmune diseases with similar clinical manifestation. Whether or not autoimmune antibodies appear first before the actual disease manifests , I can't make any comment on that . But I do hope the Schogren's test result at the ophthalmologists is a false positive. Do you have any one related to you with an autoimmune condition ?
@@MedicosisPerfectionalis I just talked to my Rheumatologist. She told me no there is nothing else that can cause those antibodies except Sjrogens yes you say yes you can have those antibodies and it not be sjogren's. I want to beleive you. . She just said to try the hydrochloriquine for six months if my symptoms improve then that's my answer. Do you think I should get a second opinion? I am gonna have the lip biopsy done too
@@MedicosisPerfectionalis can you tell me what else can give me antibodies on the early Sjogren's panel if it's not Sjogrens?? I can't find answers anywhere.
If a lip biopsy test is negative in someone with anti-ssa who has no disease syndrome, then what disease can trigger this antibody? Is it possible for someone with anti ssa not to get autoimmune disease?
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Thank you for organizing your videos into playlists. It makes it very easy to find videos.
Awesome 👏
Thank you. I have two friends with this. They suffer more than I thought. :)
SS diagnosis depends on both test results and clinical findings. Is the SS diagnosis dependent on +Ro and +La? Early SS sufferers may have a +Early SS Panel and -Ro and -La: does that mean you do nothing as far as rx because Ro and La are negative? Absolutely not! They have SS and need tx to slow the progression. Studies have found that a % of SS patients never turn +Ro and +La but they have long standing symptoms (ie 10yrs+). Also SS patients don’t necessarily have to have a second AI disorder such as RA or SLE. It may manifest down the road but in the meantime they have SS and need tx.
This “criteria” as it stands hinders a proper dx and therefor tx of many people with SS. I agree other things should be ruled out but symptoms+earlySS Panel+lymphocytic infiltration = SS. Lastly, what is the significance of having an ANA of 1:320 to dx SS? Anything above 1:80 is positive. Furthermore, the ANA number is not an indicator of severity of disease. The number can fluctuate and usually patients aren’t given the ANA multiple times. Once it’s positive, it’s positive. Just some issues to think about regarding SS. Diagnosis needs to happen as early as possible so the patient can receive tx ASAP. SS is just as serious a disorder as SLE and is too often not dx in a timely manner. Good video😊
True dis
Your way of teaching is fun as well as amazing I love reading biology more because of you and your videos which clears all my doubts can u please make video on breathing and exchange of gases (class 11) & neural controls and coordination as well😕
Have you watched my Pulmonology playlist?
I (27yr F) have almost all the symptoms of sjogren’s, slightly elevated CRP, ANA Elisa was Detected, but ANA IFA was
Thanks for this video! I have Sjogrens and it was quiet helpful.
My pleasure 😇
Be well!
Is it equivalent to cancer or Aids?
My mouth is dry 24x7
Planet Ayurveda’s amazing treatment for Sjogren’s Syndrome has been a blessing. I'm so thankful.
Periodontal doesn't mean between the teeth. The periodontal tissues are the ones "around" (hence "peri-") the tooth, which includes the gingiva, the cementum, the periodontal ligament and the alveolar bone. The periodontal diseases are basically gingivitis and periodontitis.
This is what I meant, but my description wasn’t accurate.
Thank you so much 😊
@@MedicosisPerfectionalis You are welcome! You are the one to thank, I love your videos! Keep rockin' it :D
You are brilliant, watching your videos saved hours and hours googling
Thank you 🙏
Excellent information!
Thank you 🙏
Ok, duuuuuude, I mean, doctoooooor. This video is gold !
Can STRESS make Sjögren's worse. ?
Can`t wait to see you hit 1M subscribers and more. You are amazing!
Did he just say “oh shut up”?😂
Trying to get my rheumatologist to get this lip biopsy going. I have all of the above! No one wants to do it- I wonder why?
Thank you for the videos- very helpful
I loved the video! I wonder if I might have SS. I have 47XXY Klinefelter's Syndrome and I have learned that there is a prevalence of KS in men with SS. I have chronic dry mouth, eyes and nose and am currently experiencing swollen fingers.... inflammatory arthritis perhaps?!
Listen up rheumatologists Bc youre dismissing so many even when we have positive lip biopsy. Get a clue! It’s your specialty after all!
You’re good but try and stop other comments like ‘shut up ‘ & co ... they’re harsh
Amazing videos and wonderful explanations. One of the best on youtube.
Could you please add more nephrological topics.
I need you to be my doctor
Thank you 🙏
I just got diagnosed but only after years of not knowing why all my teeth became ticking time bombs.
I'm 25 now with full dentures
I am so sorry to hear that!
Thank you so much!! I have a rheumatology exam in a couple of days and your videos are great for revision of the key concepts!!
If someone else is tone deaf like myself and the Anti-Ro/La thing didn't stick, I can tell them apart by remembering "Black Arrow"
La/SS-B: BLack
Ro/SS-A: ArRow
I wish you success on your exam!
Thank you!@@MedicosisPerfectionalis
ay roooooow, bee laaaaa :D
Haha 😂
Why we don’t use parotid gland for confirmation.... is also affected by SS?
Sjögren affects minor salivary glands.
The parotid gland is major.
Addicted to your videos since 48 hours
Haha 😂
Thank you so much 😊
@@MedicosisPerfectionalis
You really doing amazing job you making medicine specially Internal looks like a joke while our teachers make it boring like hell and difficult to digest
I will recommend all my medics teamMates
Wow 🤩
I am honored!
How to tell SLE or SS?
This guy is my new favorite. ❤❤❤
Thank you 😊
Great work ...well done
Thank you 🙏
Please can you make videos about lupus erythematosus
Sure!
@@MedicosisPerfectionalis thank you love you soo much😙😍
If a lip biopsy test is negative in someone with anti-ssa who has no disease syndrome, then what disease can trigger this antibody?
Is it possible for someone with anti ssa not to get autoimmune disease?
He said it already that SSA is not specific only for SS. Which means it can be caused by other autoimmune diseases like RA,SLE,Myositis,sarcoidosis and others. Hence the need for differetial diagnosis .
@@bughesamiombu2909 What can trigger this if there is no autoimmune diseases? Could helicobacteria in the stomach cause this? Can antibodies change in the next blood test?
@@fatihe.1338 To start with, who orders for a lip biopsy test without any clinical syndrom or without any correlating patient history?
@@bughesamiombu2909 I had dryness in my eyes as a result of clogged tear glands, my ophthalmologist said I was schorgen from the blood test. However, the rheumatology doctor could not diagnose because the salivary gland biopsy was negative. The rheumatologist said that the problem I had with the eye was from using the computer excessively. However, he said that there is a high risk of contracting this disease in the future.
Some doctors said that the antibody may be positive due to the infection in my blood. They asked me to repeat the blood test periodically.
In the articles I reviewed, it was explained that antibodies first appeared and then the disease appeared. Is this true?
@@fatihe.1338 Now I get the full picture .
Your ophthalmologist did a good job referring you to a rheumatologists with the positive test result for Schogren.
However, the rheumatologists can't diagnose you with Schogren on the basis of one positive laboratory test result. Plus in addition to that , lip biopsy came out negative .
Not enough criteria to make a diagnose .
There is a need for a differential diagnosis inorder to exclude the possibility of other autoimmune diseases with similar clinical manifestation.
Whether or not autoimmune antibodies appear first before the actual disease manifests , I can't make any comment on that .
But I do hope the Schogren's test result at the ophthalmologists is a false positive.
Do you have any one related to you with an autoimmune condition ?
Can you have the antibodies and not have Sjogrens??
Yes
@@MedicosisPerfectionalis what else beside Sjogrens can trigger those antibodies to come out and show on blood work?
@@MedicosisPerfectionalis I just talked to my Rheumatologist. She told me no there is nothing else that can cause those antibodies except Sjrogens yes you say yes you can have those antibodies and it not be sjogren's. I want to beleive you. . She just said to try the hydrochloriquine for six months if my symptoms improve then that's my answer. Do you think I should get a second opinion? I am gonna have the lip biopsy done too
@@MedicosisPerfectionalis can you tell me what else can give me antibodies on the early Sjogren's panel if it's not Sjogrens?? I can't find answers anywhere.
If a lip biopsy test is negative in someone with anti-ssa who has no disease syndrome, then what disease can trigger this antibody?
Is it possible for someone with anti ssa not to get autoimmune disease?
You are so mad and funny
Thank you ☺️