This is my first comment ever on social media but I had to comment on how great of a teacher you are. We need more teachers like you, who care about the education of others. Your videos have truly helped me in desperate times during my A&P class! THANK YOU!!!
Don't mind me. 0:22 muscle fiber types(other videos) 0:38 [Video main topic] Graded muscle responses (2 main types of stimuli) 1:03 Resting membrane potential/Threshold potential(muscle cell) 1:08 Graded Response depends on Frequency and Strength of [Neural Stimuli]-primary(Somatic) stimulus for skeletal muscle fibers 2:05 Muscle Twitch relates to Motor Unit 2:23 Twitch=Rapid muscle contraction(response) from one neural stimulus 3:10 Motor Unit= motor neuron + muscles fibers (sup by motor neuron) 3:47 Recap 4:38 Structure of skeletal muscle 5:15 3 phases of muscle twitch 1)Latent 2)Contraction 3)Relaxation 10:21-contraction(cool) 11:05 Max Voltage-end of contraction(peak?) activates gates, opens channels for potassium ions to leave cell 11:57 (Relaxation) Tension decreases- reverse slide? 12:46 Recap muscle twitch 17:32 Easy on that sodium ion influx, they say the sarcoplasmic reticulum calcium release really stings when it gets in your 👀. Later mania. What up depression.
This guy is so much dedicated to teach us and he is far away from the glamour world in which people focus on dressing well themselves he is in torn t shirt but teaching like an incomparable person🙌🙌 thank you sir 😇😇
Hi, one correction I would like to note is that the example given in the video is spatial summation since multiple neurons were used for stimulation. Temporal summation would be used in the case of one frequently firing neuron. Other than that, thank you so much for this video, these are amazing resources!
Yes! I hope that Ninja Nerds will correct this in their next video. Each muscle fiber is innervated by ONE motor neuron, and only one. Therefor, summation depends on temporal summation, not spatial.
Ninja Nerd you are gem❤, watching from India,Your way of teaching is just awesome and every single word you explained is now fixed in my mind. Thank you so much sir.
As some other comments pointed out, there is a mistake in the explanation of summation and tetanus. The skeletal muscle AP is only a few ms long, whereas the mechanical response starts with a roughly 5-10 ms delay, and finishes around 100 ms after the AP. Therefore, the sarcolemma is already repolarized even before the contraction phase of a twitch starts! Summation, incomplete and complete tetanus happens when APs on the sarcolemma are generated in a rapid succession. Under these circumstances, calcium ions are not entirely taken back to the SR before the next "package" of calcium ions are added to the sarcoplasm. So the calcium concentration is already higher than the resting level, and with the newly released calcium, it will reach an even higher peak concentration. Depending on how quick the release events happen and for how long time, it can lead to summation (the muscle does not reach maximal tension), incomplete tetanus (maximal tension is reached at the peak of contractions, but relaxation is still visible), or complete tetanus (no relaxation between the peaks).
Thank u so much for ur effort sir u r amazing and the best teacher I have ever known .I am presently in my first year mbbs ur videos help me a lot sir.keep rocking sir...... 👍
The only time i minimise the video to hit like is when the video is too too too good.....and this waz the one.....superb.....ur voice is too addictive though......😍😍😍😍
This lecture appears to be confounding a fiber stimulus (with two neurons) with a graphical representation of orderly recruitment toward unfused tetanus which involves all muscle fiber types ending with summation of S,FR,FF fiber types. Solution: The two neuron example should have been on entire muscle with each neuron stimulating a different fiber type. In other words, two separate alpha motor neurons cannot stimulate the same extrafusal muscle fiber, instead the orderly recruitment of different muscle fibers accounts for additional force.
Nice video but you may wish to review example of two distinct neurons stimulating same fiber - phyisologically any muscle fiber type can only be stimulated by one and only one motor unit that is dedicated to the target muscle from the homogenous motor neuron pool whereas one axon within the MU would deliver the action potential to its associated muscle fiber
Wait are you said neuron number two fires in muscle fiber? OR did you mean another axon terminal branch releasing ach to increase tension? Confused because you said there is only one muscle neuron for one muscle fiber.
My question about tension. What influences tension? Is it weight lifted? Or can tension be high under high perceived effort with light weight. does cross bridging = contraction force? what about fatigue and exhaustion. Doesn't more exhaustion = more cross bridging even though there is less force produced? Which would mean tension is still high?
Tnx a lot buddy , i have been seeing ur videos since a few days & ur explanation is excellent , I'd like to suggest u that u make videos which are breakdown of usmle First Aid , & explain them system wise , then u will get a large no. Of subscribers
Thank you very very much for this video bro. I always love learning from u. I have a question, is one skeletal myofiber cell only innervated by 1 neuron. Then how does twitch summation work?
I have two questions about this: 1. If the relaxation phase takes generally longer than the contraction does, then how would one improve and shorten it for example in Wing Chun to make consecutive quick punches? 2. Can a deliberate attempt be made to achieve some level of tetanus high enough to consume enough glucose to substantially lower it and even out a spike after a meal for a insulin resistant diabetic? In my case, I have problems getting sufficient oxygen delivery from an abnormally constricted vascular system, so I have a higher ratio of white to red fiber muscles. My biggest concern now is that due to insulin use, while I am gaining muscle quickly for my age (65) I gained two inches on my arms in four months, I am also gaining fat.My waist going from 34 to 36 in the same four months. I am very upset at this fat gaining and aerobic exercise does not seem to help. I was hoping if I could burn off a lot of glucose, I wouldn't need as much insulin. Aside from breakfast, I eat four onces of carbs and four ounces of protein with plenty of fats for lunch and dinner. I spike by anywhere from 80-160 mg/dl after a meal and take 16-20 units of fast acting unsulin. Any advice is welcomeand thanks for the video.
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to me too
"Your cow"
@@sinister2423 means the world if you're an indian hindu 😂
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😂 lol it’s the cow for me
This is my first comment ever on social media but I had to comment on how great of a teacher you are. We need more teachers like you, who care about the education of others. Your videos have truly helped me in desperate times during my A&P class! THANK YOU!!!
Don't mind me.
0:22 muscle fiber types(other videos)
0:38 [Video main topic] Graded muscle responses (2 main types of stimuli)
1:03 Resting membrane potential/Threshold potential(muscle cell)
1:08 Graded Response depends on Frequency and Strength of [Neural Stimuli]-primary(Somatic) stimulus for skeletal muscle fibers
2:05 Muscle Twitch relates to Motor Unit
2:23 Twitch=Rapid muscle contraction(response) from one neural stimulus
3:10 Motor Unit= motor neuron + muscles fibers (sup by motor neuron)
3:47 Recap
4:38 Structure of skeletal muscle
5:15 3 phases of muscle twitch
1)Latent
2)Contraction
3)Relaxation
10:21-contraction(cool)
11:05 Max Voltage-end of contraction(peak?) activates gates, opens channels for potassium ions to leave cell
11:57 (Relaxation) Tension decreases- reverse slide?
12:46 Recap muscle twitch
17:32 Easy on that sodium ion influx, they say the sarcoplasmic reticulum calcium release really stings when it gets in your 👀.
Later mania.
What up depression.
thank you so so much
saved me so much time, thank you! way to put your neurosis to good use... I should probably do the same haha
I just wanted to tell you, you are awesome! So glad I found this channel!!!
I have met only few people in my long journey with science who can explain like you sir 👍🏽👍🏽 keep going
Ninja Nerd is straight up the only reason I got through my first-year of vet school. You're changing lives for the better guys!
Genius. A born teacher; an educator par excellence.
Such a genius I have ever seen
The most needed person for medical students
You are my favorite RUclips instructor. No one explains things so simply as you do.
Really I can imagine how nice ur teachers taught u
Really u r so blessed
And thanks for helping many students
Stay blessed
omg thank you so much!!! i can't believe some one caring this much to inform people .appreciate
I can never thank you enough for your videos please never stop making videos you are one of the most amazing teacher on youtube
This guy is so much dedicated to teach us and he is far away from the glamour world in which people focus on dressing well themselves he is in torn t shirt but teaching like an incomparable person🙌🙌 thank you sir 😇😇
Never met anyone this smart. Not even my lecturers can contend. No cap...thank you very much
Damn... this is gold I found, gold I say!!
+vallc16 lol!!! I'm glad you enjoyed it!!
holy shit, talk about being able to simplify this and get the science across!!!!!! this is worth more than gold
I can’t thank you enough for the push you have given me through these tutorials. I get time to recap everything before my exams.
Good luck on the exams! -TG
Thanks for your kindness and services!! ✨✨
Thanks for your kindness and services!! ✨✨
Thanks for your kindness and services!! ✨✨
Thanks for your kindness and services!! ✨✨
I'm so in love with this channel now fr this was my first time on the channel and learnt a lot thanks blud
i will never tire of saying that you are the best teacher and this is the most amazing channel ever!!!!!!!!
Really , Sir this is amazing lecture I 'ever found thankyou Sir for wonderful explanation . Love From India May god bless you ..
Resting membrane potential -90mv 3:48
Threshold -55
Peak potential +30mv 10:50
Load & resistance 18:38
Hi, one correction I would like to note is that the example given in the video is spatial summation since multiple neurons were used for stimulation. Temporal summation would be used in the case of one frequently firing neuron. Other than that, thank you so much for this video, these are amazing resources!
Indeed, finally someone who comments about it.
Yes! I hope that Ninja Nerds will correct this in their next video. Each muscle fiber is innervated by ONE motor neuron, and only one. Therefor, summation depends on temporal summation, not spatial.
No man, it is Temporo-Spatial or the mixed one.
You're explaining right from your heart, thank you so much
WOW! I haven't met anyone who can explain science the way you explained and you are explaining from your heart and very easy to understand. Thank you!
Ninja Nerd you are gem❤, watching from India,Your way of teaching is just awesome and every single word you explained is now fixed in my mind.
Thank you so much sir.
For sure you are a good teacher, I really appreciate you, and the way you are teaching, thank you much . May God bless you
Hi, i´m glad you take your time to make these videos, I really apreciate your effort . You're my inspiration. Thanks,keep doing videos please !
this man has a natural God given talent
you are a life savior. keep up the good work
Thank you sm for your videos! ❤️ I don’t normally comment but seriously thankful for you making this a little easier to learn!
As some other comments pointed out, there is a mistake in the explanation of summation and tetanus. The skeletal muscle AP is only a few ms long, whereas the mechanical response starts with a roughly 5-10 ms delay, and finishes around 100 ms after the AP. Therefore, the sarcolemma is already repolarized even before the contraction phase of a twitch starts!
Summation, incomplete and complete tetanus happens when APs on the sarcolemma are generated in a rapid succession. Under these circumstances, calcium ions are not entirely taken back to the SR before the next "package" of calcium ions are added to the sarcoplasm. So the calcium concentration is already higher than the resting level, and with the newly released calcium, it will reach an even higher peak concentration. Depending on how quick the release events happen and for how long time, it can lead to summation (the muscle does not reach maximal tension), incomplete tetanus (maximal tension is reached at the peak of contractions, but relaxation is still visible), or complete tetanus (no relaxation between the peaks).
Guys believe me u need no Textbooks when u have Ninja Notes ,,,Cover almost all Guyton and Hall Love u Sir
Thanks so much,,,so so informative and understandable 🙏🤍
THIS IS AMAZING THANKYOU SO MUCH FOR THE EFFORT ❤️
You
Are
A
Wonderful
Teacher.
Thank
You
LEGEND ❤️❤️
You are SAVING my life. 🙏🏼
Thank u so much for ur effort sir u r amazing and the best teacher I have ever known .I am presently in my first year mbbs ur videos help me a lot sir.keep rocking sir...... 👍
THIS SAVED MY LIFE
You are one of those spoon feeding Teachers!! Thank you much, Science got easier because of you.
Amazing teaching man! It really makes it easier to understand and grasp the concepts. Love it
thank you, your video help me to understand this topic, i will take the exam soon
Thank u, thank u, thank u so much sir. Love from India. Don't know which country you belong to but you explained very nicely.
You make medicine easy. Thank you so much!
i am so appreciated from your teaching!
OMG! It's way beyond amazing!
Just EXCELLENT!
Thanks for this obvious illustration
Actually ... U're my hero sir following u from Algeria 🇩🇿
U are the best. Well explained. Thanks for this.
+Ugonwa monet Okoro You are so nice! Thank you!
This was much more understandable than my prof and books combined. 👌🏻 thank you so much!
Phenomenal lecture 👌 👏 🙌 Thank you so much ❤
Thank you. I should have watch your video. I wasted my whole day try to understand this stuffs.
You are so awesome! Thank you for making this amazing videos. Better than my professors.
you really saved my life thanks
learned more in 30 min than in 2 months
OMG thank you for this! You are a lifesaver!!!
+Aubrey Banguis awesome!!! I'm so happy that we were able to help you thank you for the positive feedback!
man is carrying me through A&P
Eloquent and excellent
Great explaination! God bless you
Thank you love from india 🙏🇮🇳🌹
Chandni Singh me too
This helps so much--Thank you!
Thank you so much sir I really wish you achieve everything you ever wished for thank you sir once again
This is so helpful omg
You are awesome!
You are the masterpiece!!
Magically wonderful
The only time i minimise the video to hit like is when the video is too too too good.....and this waz the one.....superb.....ur voice is too addictive though......😍😍😍😍
awesome as always, thank you
No words sir 🙏🏼🙏🏼❤️🇮🇳🇮🇳
Your videos are amazing !!!!!!
Very well explained sir, thank you. deserves a big like :)
This lecture appears to be confounding a fiber stimulus (with two neurons) with a graphical representation of orderly recruitment toward unfused tetanus which
involves all muscle fiber types ending with summation of S,FR,FF fiber types. Solution: The two neuron example should have been on entire muscle with each neuron stimulating a different fiber type. In other words, two separate alpha motor neurons cannot stimulate the same extrafusal muscle fiber, instead the orderly recruitment of different muscle fibers accounts for additional force.
Yeahhh, had the same doubt....thnx for commenting
Great lesson, thanks!
+Samantha Rossi So happy we were able to help!!!
Nice video but you may wish to review example of two distinct neurons stimulating same fiber - phyisologically any muscle fiber type can only be stimulated by one and only one motor unit that is dedicated to the target muscle from the homogenous motor neuron pool whereas one axon within the MU would deliver the action potential to its associated muscle fiber
Great. Thanks for the informative presentation.
your videos blow my mind, thank you!!!!!!!!!!x100000000
Amazing 🌸✨
Wait are you said neuron number two fires in muscle fiber? OR did you mean another axon terminal branch releasing ach to increase tension? Confused because you said there is only one muscle neuron for one muscle fiber.
Great knowledgeable video, thanks a ton!!!
Thank you doc 💓
Absolutely PERFECT explanation!!! Flawless presentation! Thank you so much for making this video!
where have you been all my life? THANK YOU SO MUCH
Amazing! Thank you!
great detailed explanation
Very helpful, thank you sir
Amazing thank you
Dis guy is the bestest
My question about tension. What influences tension?
Is it weight lifted? Or can tension be high under high perceived effort with light weight.
does cross bridging = contraction force?
what about fatigue and exhaustion. Doesn't more exhaustion = more cross bridging even though there is less force produced? Which would mean tension is still high?
THE GREATEST
Wow, thank you so much!
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Zach I love you
Tnx a lot buddy , i have been seeing ur videos since a few days & ur explanation is excellent , I'd like to suggest u that u make videos which are breakdown of usmle First Aid , & explain them system wise , then u will get a large no. Of subscribers
Your the best. Couldn't ask for more!!!
Thanks i pray for you.
Thank you very very much for this video bro. I always love learning from u. I have a question, is one skeletal myofiber cell only innervated by 1 neuron. Then how does twitch summation work?
That was actually my question.
Muscles are Innervated nerves, which are a bundle of axons
thank you so much from Kurdistan
you videos helps me alot ,making studies easier...thank you
I have two questions about this:
1. If the relaxation phase takes generally longer than the contraction does, then how would one improve and shorten it for example in Wing Chun to make consecutive quick punches?
2. Can a deliberate attempt be made to achieve some level of tetanus high enough to consume enough glucose to substantially lower it and even out a spike after a meal for a insulin resistant diabetic?
In my case, I have problems getting sufficient oxygen delivery from an abnormally constricted vascular system, so I have a higher ratio of white to red fiber muscles. My biggest concern now is that due to insulin use, while I am gaining muscle quickly for my age (65) I gained two inches on my arms in four months, I am also gaining fat.My waist going from 34 to 36 in the same four months. I am very upset at this fat gaining and aerobic exercise does not seem to help. I was hoping if I could burn off a lot of glucose, I wouldn't need as much insulin. Aside from breakfast, I eat four onces of carbs and four ounces of protein with plenty of fats for lunch and dinner. I spike by anywhere from 80-160 mg/dl after a meal and take 16-20 units of fast acting unsulin.
Any advice is welcomeand thanks for the video.
thanks so muchhhh for this video! really helped me for uni to understnand smooth and incomplete tetanus :)))
So helpful