Excitation-Contraction Coupling... in steps 1. Wave of action potential spreads away from motor end plate in all directions. 2. Once the wave reaches the transverse tubules (T-Tubules) it continues down them into the sarcoplasm of the muscle fiber. 3. Next, action potential stimulates the opening of voltage gated ion channels in the T-Tubules which are linked to calcium channels in the terminal cistern. 4. Calcium channels open and diffuse out into the cytosol 5. Calcium ions will bind to the troponin of the sarcomeres thin filaments (actin) 6. That binding allows the shape to change and move into a grove on the actin, which exposes active sites where myosin heads can now bind too.
I thought that channels in T tubules that are linked to channels in SR are Ca2+ voltage gated (DHP receptors) as well. Or are they actually Na+ voltage gated? I'm so lost
![COLOMBIA vs. CHILE [4-0] | RESUMEN | ELIMINATORIAS SUDAMERICANAS | FECHA 10](http://i.ytimg.com/vi/TDjN4W3yy1k/mqdefault.jpg)
how can a 1 minute video be so beautifully clear and concise. i shed a tear
Excitation-Contraction Coupling... in steps
1. Wave of action potential spreads away from motor end plate in all directions.
2. Once the wave reaches the transverse tubules (T-Tubules) it continues down them into the sarcoplasm of the muscle fiber.
3. Next, action potential stimulates the opening of voltage gated ion channels in the T-Tubules which are linked to calcium channels in the terminal cistern.
4. Calcium channels open and diffuse out into the cytosol
5. Calcium ions will bind to the troponin of the sarcomeres thin filaments (actin)
6. That binding allows the shape to change and move into a grove on the actin, which exposes active sites where myosin heads can now bind too.
Thank you so much
شكرا❤❤❤❤❤
So basically... this is like the "first step" to the sliding filament model/process?
Literally made so much more sense than my textbook; thank you!
taught me more in less than 2 min than my professor did in an hour!!!
Frrr
Frrr
FOR REAL except 3 hours for me
صح ❤❤
I thought that channels in T tubules that are linked to channels in SR are Ca2+ voltage gated (DHP receptors) as well. Or are they actually Na+ voltage gated? I'm so lost
Concise, great visuals, thank you so much.
You're very welcome!
wow, this was so clear and concise! great video!
Amazing! Thanks a whole lot.
I really needed this! Thank u so much
Really good video. Thank you, StudentHelp4AP!
Glad it was helpful!
اول عربي هنا ادرس طب بشري في مصر جامعة القاهرة قصر العيني ❤❤
Good demonstration
Good content 👍
جميل المحتوى❤❤
thanks homie
amazing video lecture and presentation..but you are too fast in explaining the process
This is the reboot: ruclips.net/video/hBQEitajf_U/видео.html
Still confused 🤷🏽♂️
Great clip!
Superb vedio.thank you
Everyone is explaining skeletal muscles ....I wanted a 3D video about smooth muscles ,but no one do so😢
Great Clip!!!
Very useful
Nice video
Thnx it was helpful ❤️
Fantastic
thankyou very muchhh
I don't really know why I have to know this.
scientific literacy
THANJKKKK YOOOUUU
Hi kapv guys
🔥
taught me more in less than 2 min than my professor did in an hour!!!