Partially correct... *Yes p>c if there is renal insufficiency *Yes c>p if the infection is primarily in the kidneys (c is concentrated in the kidneys), for all other systemic infections p>c (he didn't clearly mention the second part) *P is traditionally mixed in dextrose but it isn't mandatory. Recent stability data suggests that p is stable in various diluents including NS, D5, 0.5NS/D5, 0.25NS/D5 No mention of some of the negatives of c, like it's given as a prodrug and therefore long time taken to reach effective concentration, requirement of high loading dose, loading dose being very toxic etc.
Sir kindly clarify When to give Poly B and When to give Colistin?? For example if Acinitobacter is there in BSI Blood , then Poly B or Colistin? And if there is VAP and BSI both , then which one to prefer : Poly B or Colistin?? Kindly clarify with explanation
Partially correct...
*Yes p>c if there is renal insufficiency
*Yes c>p if the infection is primarily in the kidneys (c is concentrated in the kidneys), for all other systemic infections p>c (he didn't clearly mention the second part)
*P is traditionally mixed in dextrose but it isn't mandatory.
Recent stability data suggests that p is stable in various diluents including NS, D5, 0.5NS/D5, 0.25NS/D5
No mention of some of the negatives of c, like it's given as a prodrug and therefore long time taken to reach effective concentration, requirement of high loading dose, loading dose being very toxic etc.
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Very nice
Sir kindly clarify When to give Poly B and When to give Colistin??
For example if Acinitobacter is there in BSI Blood , then Poly B or Colistin?
And if there is VAP and BSI both , then which one to prefer : Poly B or Colistin??
Kindly clarify with explanation
please tell how to give these two medicines
over 1-2 hours.
Sir in acute kidney injury patient with creatinine clearance less than 15 ml / hr is possible to give any of. This agent?
Sir how to calculate colistin dose?
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