Life and Longevity: Crash Course History of Science #44

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  • Опубликовано: 29 ноя 2024

Комментарии • 176

  • @Taiwannabe
    @Taiwannabe 5 лет назад +15

    Is there any way you could do a series on the evolution of language? It's fascinating for me to read about and it seems like a topic that you guys would do a great job with!

  • @predatoryanimal6397
    @predatoryanimal6397 5 лет назад +6

    Got A+ in molecular biology last semester, I’m glad they didn’t ask crisper history questions.

  • @Souchirouu
    @Souchirouu 5 лет назад +50

    My brain definitely could use some CRISPR'ing up.

  • @djan2307
    @djan2307 5 лет назад +24

    5:42 Emmanuelle Charpentier is french, not swiss.

  • @tommyrosendahl7238
    @tommyrosendahl7238 5 лет назад +12

    Would you consider doing an episode on the future of basic academic research vs. applied research at the universities?

  • @harsharya3739
    @harsharya3739 5 лет назад +36

    Early in the game of longetivity. Ironic

  • @ShadowParalyzer
    @ShadowParalyzer 5 лет назад +5

    One movement I've been keeping my eye on is rejuvenation biotechnology. I recommend watching some of Aubrey de Grey's talk on his take of combating aging as he defines aging as the accumulation of damage over the course of one's life. He classified this damages into 7 broad collections, and he is using a divide and conquer approach to tackle them. Things seem to be going well enough that he foresees "Robust Mouse Rejuvenation" 3-5 years away - which has the importance of convincing more experts about the feasbility of countering aging using a rejuvenative approach.

  • @Biomeducated
    @Biomeducated 5 лет назад +1

    It was 7 am when I woke up here in Belgium. Searched for Biomedicine on YT. Landed on Crash Course. Watched #34 (Biomedicine), #40 (Biotechnology), #41 (Bodies & Dollars) and this one #44 (Life and Longevity). What an excellent Sunday morning to start off with! Now time for a run to process all the info :D

  • @francoislacombe9071
    @francoislacombe9071 5 лет назад +46

    "What happens when life itself becomes a technology?" The Protomolecule.

    • @__Andrew
      @__Andrew 5 лет назад +1

      Fingers crossed for July....

  • @alesolano5507
    @alesolano5507 5 лет назад +8

    Charpentier and Doudna will receive the Nobel prize sooner or later for sure, but I hope Francis Mojica gets a piece of the cake. The impact of a scientitic Nobel prize in Spain would be huge. Maybe irrational, but after Cajal won the prize back in 1906, lots of young students pursued a career on Medicine/Neuroscience research successfully and some folks still mention him as a motivation today. National pride can be positive if you know individually how use it, always knowing that it's not the most rational thing.

    • @BenTajer89
      @BenTajer89 5 лет назад

      Cajal's beautiful illustrations I think are a big part of it.

    • @Biomeducated
      @Biomeducated 5 лет назад

      Could be a repeat of 1962, where Rosalind Franklin didn't get a piece of the cake...

    • @hubermanlab
      @hubermanlab 5 лет назад +2

      @@Biomeducated Who gets the Nobel is rarely surprising, but who doesn't get it often is.

  • @notinuse2298
    @notinuse2298 5 лет назад +14

    I can tell this is going to be a interesting episode.

    • @vksepe
      @vksepe 5 лет назад +1

      I WANNA LIVE FOREVER

  • @lncerante
    @lncerante 5 лет назад +3

    11:09 THANK YOU, that worries and enrages me so much

  • @jameswallace9906
    @jameswallace9906 5 лет назад +1

    Hank is one of my favorite people

  • @iinavpov
    @iinavpov 5 лет назад +33

    I'm a bit sad that this segment makes it seem like gene therapy is an American thing, whereas the only actual treatments that are available and work are the result of French and Italian efforts. Because it's so very hard and having secure employment allowed scientists notably at the San Rafaele in Milan to actually make it work.

  • @debrachambers1304
    @debrachambers1304 Год назад +1

    11:47 "IS A" seems like an odd choice of what to highlight. The highlights do often feel oddly chosen to me, but this is especially strange.

  • @ohtheblah
    @ohtheblah 5 лет назад +28

    CRISPR... the app you swipe right on sexy apples

  • @Bobols91
    @Bobols91 5 лет назад +5

    They talk also about it in
    r/longevity

  • @ElGringoCastellano
    @ElGringoCastellano 5 лет назад +5

    I love CRISPR-CAS9

  • @AbbeyRoadkill1
    @AbbeyRoadkill1 5 лет назад +10

    Best episode yet. Big ups, Crash Course! 🙌

  • @jmhorticulture5230
    @jmhorticulture5230 5 лет назад +3

    His drip is pure water

  • @lloydy272
    @lloydy272 5 лет назад +4

    Strange definition of Omics, Hank. Omics is a term to not describe the study of small things as you implied, but to study the state of all these small things at once. Genetics studies genes, genomics studies all the genes and all the DNA in a cell/organism. Molecular genetics studies how transcripts are made but transcriptomics studies all the transcripts at once.
    Citation: I work in a genomics lab and have in-depth experience performing both molecular genetic and transcriptomic studies.

    • @betin731
      @betin731 5 лет назад

      I though that they were robots

  • @Eamonnhickson
    @Eamonnhickson 4 года назад

    Thank you for the fantastic video

  • @rmya
    @rmya 5 лет назад +5

    hey guys! i'm going to college next september and i want to study biotechnology! but unfortunately, my extended family think it's a risky field of study and that there isn't job security with it. (they want me to study medicine)
    how do i convince them that biotech is a field that is worth studying? any tips or things i could say to them?

    • @XlxscionxlX
      @XlxscionxlX 5 лет назад +3

      make a power point presentation? but seriously what a cool thing to study, good luck with that!

    • @rmya
      @rmya 5 лет назад +2

      @@XlxscionxlX that's actually a good idea! thank you so much! but sometimes i do think that they might be right and if i study medicine first and THEN got into biotech, it might be a better investment for the future.

    • @marley_lune9750
      @marley_lune9750 5 лет назад +1

      Maybe tell them about what the field is about, maybe they don't really know. You could explain that in the 21st century, biotech is a quickly developing field which will probably be prosperous for a long time. Maybe you can look for the average salary of workers in biotech companies (i bet they are really good salaries), or tell them about some new technology the field has invented.
      PS: I hope it all works out! Biotech is an awesome field to study :)

    • @Biomeducated
      @Biomeducated 5 лет назад

      Just say they're crazy... Biotech is the future! New start-up companies are popping up like crazy around the university hubs where I live (Belgium)!

    • @safiyeserdengecti7487
      @safiyeserdengecti7487 5 лет назад +2

      Biotech is a hugely growing field (just took an Biotech exam today:)), and if you work on nanoparticles or drug delivery systems, there is a lot of money involved in research of novel treatments as well :D you can research yourself more and inform your parents about these.

  • @adrianfaith7259
    @adrianfaith7259 5 лет назад +1

    Hey Crash Course, Im looking Forward of making Crash Course Linguistics. Its super dope, and Others like me who wants an aid before going to college, be prepared and kinda view what Linguistics is and its Coverage.
    Thanks for making me knowledgeable.

    • @Tfin
      @Tfin 5 лет назад

      Yes, please help this person learn language.

  • @donavanblue9247
    @donavanblue9247 5 лет назад +1

    as with all humans throughout history & what we do/with to one another this is all great news, nothing at all scary or dark here at all.

  • @cah8291
    @cah8291 5 лет назад +2

    Thank you! Do you know of a magazine or website that updates on health sciences and the omics?

  • @camiloiribarren1450
    @camiloiribarren1450 5 лет назад +9

    Now it’s all about genetic engineering, GMOs and designer babies! Awesome! More genetics!!

  • @sarahleonard7309
    @sarahleonard7309 5 лет назад +17

    Ah, if only basic research could get funded these days...

  • @renauddessalles3876
    @renauddessalles3876 5 лет назад +4

    I think that Emanuelle Charpentier Is French not Swiss

  • @shurnelmarumo8881
    @shurnelmarumo8881 5 лет назад +1

    This is awesome💖

  • @emr2425introibo
    @emr2425introibo 5 лет назад +16

    Omics sounds like a race out of sci-fi novel.

    • @Tfin
      @Tfin 5 лет назад +1

      Ol·mec/ˈälˌmek,ˈōl-/noun
      noun: Olmec; plural noun: Olmec; plural noun: Olmecs1. a member of a prehistoric people inhabiting the coast of Veracruz and western Tabasco on the Gulf of Mexico ( c. 1200-400 BC), who established what was probably the first Meso-American civilization.
      But to call a group of sciences "the omics" when it doesn't include all the "-omics," like say "econ-" and "gastron-" is just pointless. You can only use the term in a group of people who already know which things you're talking about.

  • @geoffreywinn4031
    @geoffreywinn4031 5 лет назад +1

    Educational!

  • @jangapardhu5300
    @jangapardhu5300 4 года назад +1

    What's with companies' obsession with patents.??

  • @lindavilmaole5003
    @lindavilmaole5003 5 лет назад +1

    I found the following lines very important: "Regardless of how immediately revolutionary or still-science-fictional the various life-control technologies we covered in this episode are, they have one thing in common: Rich people will get them way before poor people. And old technologies won't go away due to new ones. Science, in the sense of set of methods for understanding the natural world. doesn't tell us which technologies we should deploy, when or when. This is the real of ethics." Ethics should be observed by the disciples of science or by the followers of science.

    • @skylight6820
      @skylight6820 5 лет назад

      The existence of an individual human being or animal so it is a life.
      Today, doctors and nurses use handheld devices to record patients' real-time data and instantly update their medical history. This makes more accurate and more efficient diagnoses and treatments. Centralization of critical patient data and lab results has really improved the quality of healthcare. as well as Medicine had always relied on technology such as scalpels, probes and materia medica. However, by the start of the 20th century new instruments were available to study, diagnose and treat the body. Today, hospitals worldwide use complex, computerised machines to image the body or assist its function.

    • @reysiejaycuares5289
      @reysiejaycuares5289 5 лет назад

      CRISPR is not free or one hundred percent perfect. But this is the most efficient way to edit genes right now, and it can revolutionize medicine and agriculture. Who "invented" CRISPR? Our little buddies, bacteria! And archaea, the strange uncle of bacteria. Many germs use CRISPR to maintain a list of viruses that can kill them by putting bad DNA between repeat palindromes. This is similar to the police catalog of previous arrests: when a virus enters a microbe cell, if recognized, CRISPR-associated protein cuts the virus. And the system is a good editor: she reads for specific DNA sequences and only cuts them. ThoughtBubble, show us more: Spanish microbiologist Francisco Mojica first published this system in 1993. But then he saw a group of repeating segments of DNA with a strange different DNA between them. He did not know what this meant, and that was not the main news. But Mojica did not give up. In 2003, after a long decade of clever bio-information work, Mojica realized that CRISPR should be an adaptive immune system, a way to protect germs from viruses. But CRISPR alone did not help people. In fact, when Mojica presented his discovery to the scientific journal Nature, they rejected It! CRISPR was supposed to be turned into a tool. There were many steps and scientists. Firstly, scientists had to go beyond the search for palindromic repeats in different microbes. to understand how the whole system works: what cutting protein said, where to cut? How can I reprogram the system? Swiss microbiologist Emmanuel Charpentier and German microbiologist Jörg Vogel found that a special piece of nucleic acid, called the RNA guide, tells Cas9 Protein to cut DNA in the right place. Other scientists have developed how to transfer the whole system, which has evolved in microbes, into the cells of mice and humans, a whole system of genes tracing RNA and proteins. In 2011, Charpentier met American structural biologist Jennifer Dudna, and they decided to collaborate in the study of synthetic CRISPR systems outside of microbes. Meanwhile, in Cambridge, Massachusetts, Sino-American molecular biologist Feng Zhang and synthetic biologist George Church have worked on introducing CRISPR systems into mammalian cells. For example, Zhang created murine models of human diseases using CRISPR. In less than ten years, CRISPR has evolved from a cold immune system for germs to a hot new tool in biology. Thanks, ThoughtBubble. After turning CRISPR from a microbiological trick into an instrument of future biology, Dudna and Charpentier filed patents through their universities to work with their companies ... as did Zhang and Church for their companies. These biologists are academics, but they are also entrepreneurs. So why is CRISPR such a big deal? Instead of partial steps, each of which can lead to failure, CRISPR allows you to be fully programmed right away. This is not super simple, but simpler than before. Suggested applications include precision medicine, as well as a new green revolution: imagine that the main crops have been edited to put their own nitrogen in the ground. Or exhale less water, requiring less watering. Or for more efficient photosynthesis. Or make more nutrients that people want.

    • @iftisambalindong7381
      @iftisambalindong7381 5 лет назад

      I found this very interesting episode because it show how scientist are still trying to invent new technologies or medicine that can make the life of human or animals longer. Scientist are discovering medicine to treat the disease that can cause harm to our body. But this episode shows the what ifs of the scientist that might come true, like what if they could make a drug that can directly heal or help the specific part of our brain or body. Right now physicians are using new technologies that can help the patient to make their life even longer. And some are still trying to discover or invent a technology that can make our life longer, I'm excited to witness that machine or technology that they could invent.

    • @naipahmamao3988
      @naipahmamao3988 5 лет назад

      Invest on a promise. Science now is really a big business :( . I am happy for the freedom given to Scientists today that were taken away from the majority of the great scientists before. However, the price for this freedom is expensive. Scientists now must make something that is not only useful but also profitable or even more profitable than being useful. Honestly, will the way we perceived science create a social division again? It is nice how we formulate ways on how we can cure diseases but its off-target effects and how this will be given to people unequally, that is so not nice. We are not science-oriented, we are business-oriented. So let us clarify it; we are not after the honor science could give us, we are after the riches it could buy us.

    • @nashimaguinaresmail3765
      @nashimaguinaresmail3765 5 лет назад

      The study of longevity genes is a developing science. It is estimated that about 25 percent of the variation in human life span is determined by genetics, but which genes, and how they contribute to longevity, are not well understood. A few of the common variations (called polymorphisms) associated with long life spans are found in the APOE, FOXO3, and CETP genes, but they are not found in all individuals with exceptional longevity. It is likely that variants in multiple genes, some of which are unidentified, act together to contribute to a long life.
      One study, published in the journal Circulation last year, even argued that adhering to just five healthy habits could extend your lifespan by roughly a decade. Here’s what they are, and what research to date says about living your longest life:
      1.Eating a healthy diet
      2.Exercising regularly
      3.Maintaining a healthy body weight
      4.Drinking only in moderation
      5.Not smoking

  • @515leopard
    @515leopard 5 лет назад +2

    Congress: No, you can’t patent DNA, or anything *invented by evolution*
    Evolution: copystrike

  • @anandananda2277
    @anandananda2277 5 лет назад +20

    Remember, genes are NOT blueprints. This means you can't, for example, insert "the genes for an elephant's trunk" into a giraffe and get a giraffe with a trunk. There are no genes for trunks. What you CAN do with genes is chemistry, since DNA codes for chemicals. For instance, we can in theory splice the native plants' talent for nitrogen fixation into a terran plant.
    ~Academician Prokhor Zakharov, "Nonlinear Genetics"

    • @someshyv
      @someshyv 5 лет назад

      Is it a book or a talk? Cant find it anywhere

    • @someshyv
      @someshyv 5 лет назад

      It's a game. Got it.

  • @rparl
    @rparl 5 лет назад +1

    Seven foot two // Eyes of blue // Coochie coochie coochie coo. // Does anybody own my guy?

  • @Waltham1892
    @Waltham1892 5 лет назад +3

    Lets cut to the chase.
    How long until I get to grow hawk-wings?

    • @denniscat9395
      @denniscat9395 5 лет назад

      LOLZ nice

    • @jacobwoodbury6073
      @jacobwoodbury6073 5 лет назад

      That requires so many genes it's probably not feasible in our lifetime. The more complex a trait (a wing!) the more edits you need - and each of those individual edits carries a risk 😫

    • @Waltham1892
      @Waltham1892 5 лет назад

      @@jacobwoodbury6073 Blah, Blah, Blah. WHERE ARE MY WINGS!

    • @RoScFan
      @RoScFan 5 лет назад +1

      @@Waltham1892 If you want to fly youll need a lot more than wings. There s nothing on this planet that weighs 80 kg and flies on its own. Pterodactyls were very heavy compared to humans but light for their size. Wings wont get you anywhere. Your entire body would have to be changed. The wings would have to be pterodactyl sized, accompanied by muscles like those of the Hulk and your respiratory and circulatory systems changed to feed such wings. You d be better off with a jet pack. Me, I want a limitless style drug and to stay 25 for 500 years.

    • @Waltham1892
      @Waltham1892 5 лет назад

      @@RoScFan never tell me the odds!

  • @Arshva
    @Arshva 5 лет назад +3

    I'm just worried we'll science ourselves into an evolutionary cul de sac somehow.

    • @ferencgazdag1406
      @ferencgazdag1406 5 лет назад

      We, as any other form of life, humans don't want evolution to happen, therefore an evolitionary cul-de-sac is a good idea.

  • @Chupabrah
    @Chupabrah 5 лет назад +1

    I'm still confused about what the "crispr patent" the two parties are fighting over is for.

  • @XlxscionxlX
    @XlxscionxlX 5 лет назад

    1:36 Hey! Myriad genetics, patent this *grabbing my groin*

  • @AverytheCubanAmerican
    @AverytheCubanAmerican 5 лет назад +32

    And guess who lives a long life just by living off grass and horses? Wait for it....the Mongols

    • @wf4860
      @wf4860 5 лет назад

      Did they have long lives?

    • @patsavin974
      @patsavin974 5 лет назад

      William Fellows not really

  • @Navesblue
    @Navesblue 5 лет назад +4

    Aaaahhh technology. Turning people into products more and more as time passes on. Happy dreaming everyone! ;D

  • @thomasturner6980
    @thomasturner6980 5 лет назад +8

    I wish I lived during times of the Old Testement cuz they lived for 900 years back then

    • @TomPatricks
      @TomPatricks 5 лет назад

      Thomas Turner yeah, but no toilets or sandwiches

  • @PennyAfNorberg
    @PennyAfNorberg 5 лет назад +1

    If the wheel keeepts accerating, future cure ought to come down in cost quite fast, well not in the usa but...

  • @federickho8169
    @federickho8169 5 лет назад

    Can anybody tells me what course to study in undergraduate and postgraduate to be involved in CRISPR research ?

  • @banjaxed8334
    @banjaxed8334 5 лет назад

    11:08 comrade Hank

  • @paintswithlead7517
    @paintswithlead7517 5 лет назад +1

    could you the source materiel.

  • @juanantoniopallarueloelvir6466
    @juanantoniopallarueloelvir6466 5 лет назад +1

    Why do I feel like I am watching a science fiction show?

  • @allangustavobs
    @allangustavobs 5 лет назад

    Do a video about Sir. Willian Osler

  • @algomi9280
    @algomi9280 5 лет назад

    That moment when humanity cures aging o .o

  • @LeafLeafy
    @LeafLeafy 5 лет назад +1

    What is going on with the word highlighting at 11:45?

  • @joeivanaquino7184
    @joeivanaquino7184 5 лет назад +1

    Please Crash Course Archeology and Crash Course Theology

    • @hafizajiaziz8773
      @hafizajiaziz8773 5 лет назад +1

      By "Theology", did you mean "Religious Study" ?
      Because those are 2 different things

    • @ohtheblah
      @ohtheblah 5 лет назад

      Crash course theology - ancient people with schizophrenia tell people shellfish and bacon are bad and Greek gods fart lightning from the clouds and mt Olympus

    • @joeivanaquino7184
      @joeivanaquino7184 5 лет назад +1

      Theology doesn't relate to Greek Mythology. It usually related Judeo-Christian Philosophy

    • @hafizajiaziz8773
      @hafizajiaziz8773 5 лет назад

      @@joeivanaquino7184 So, you did mean "Theology", and not "Religious Study"

  • @les_crow
    @les_crow 5 лет назад

    Your previous video is private?

  • @emr2425introibo
    @emr2425introibo 5 лет назад +2

    Smart pills🖒

  • @fikriyeolmez4265
    @fikriyeolmez4265 5 лет назад +13

    those OMICS cannot work if you do not have got the econOMICS!
    therefore, money matters.

  • @ohtheblah
    @ohtheblah 5 лет назад +4

    All your base pairs are belong to us

  • @victormaze4851
    @victormaze4851 5 лет назад

    The intro reminded me of the incredibles song🤣

  • @danielbickford3458
    @danielbickford3458 5 лет назад

    At about the 11 minute mark , I can almost guarantee the moment the technology to download things directly into your brain becomes public someone will use it to download smut

  • @aroubg186
    @aroubg186 5 лет назад

    Can we have a medical crash course

  • @drtechtek2165
    @drtechtek2165 5 лет назад

    well, FMRI allows to "see" the oxygen in different parts of the brain.

  • @jerrybender6633
    @jerrybender6633 5 лет назад

    Not real big on eggplant background-- Have u considered pictures or light colors water colors beige tans n blues?

  • @ok-water5365
    @ok-water5365 5 лет назад +1

    Why are you so smart

  • @youngarch1811
    @youngarch1811 5 лет назад

    Where is John Grinn

    • @glennmatthews758
      @glennmatthews758 5 лет назад +1

      Green*

    • @glennmatthews758
      @glennmatthews758 5 лет назад

      Or Greene, but I know it's not Grinn

    • @ohtheblah
      @ohtheblah 5 лет назад

      @@glennmatthews758 but you don't know yt let's you edit your comments...?

  • @spawn2592
    @spawn2592 5 лет назад

    Rich people problem

  • @Metacognition88
    @Metacognition88 5 лет назад

    Isn't Emmanuele French?

  • @shagituz
    @shagituz 5 лет назад +1

    Again attacks eugenics....

  • @avi12
    @avi12 5 лет назад

    BCI example: Neuralink by Elon Musk

  • @benyamin6085
    @benyamin6085 5 лет назад +1

    God bless @crashcourse

  • @melodyjade6854
    @melodyjade6854 5 лет назад

    I'm so early this time none of the comments have likes...........

  • @sisyphusvasilias3943
    @sisyphusvasilias3943 5 лет назад

    If rule35 is a truism.. there is Hank Gay Hentai.

  • @yg853
    @yg853 5 лет назад +1

    Didn't know how where yo ask but can you make a video talking about what socialism,capitalism,communism are and what their likes/dislikes are?

  • @Metacognition88
    @Metacognition88 5 лет назад

    I will take 1 immortal pill please.

  • @froufrou4172
    @froufrou4172 5 лет назад +5

    The richer people get, the dumber they become.

  • @Black_Corey
    @Black_Corey 4 года назад

    Being against "designer babies" is idiotic. It's the same as being antivax.

  • @erojasc4304
    @erojasc4304 5 лет назад +4

    Omg I have the Biggest crush on this due whyyyyyy 🤓🤪💋 lol ok back to anatomy zzz lol

  • @sisyphusvasilias3943
    @sisyphusvasilias3943 5 лет назад

    Can we pls just outlaw patenting generative DNA.

  • @susanmaddison5947
    @susanmaddison5947 5 лет назад +1

    It might help you to think more seriously about social and political problems, but meanwhile it would surely help your videos to stop mixing so many unexamined conventional wisdom about them in with your expositions of science. The latter parts of your expositions have the merit of being sound and solid. It is a pity that you compromise them with poorly thought through political prejudices.

    • @alaskaoalaska
      @alaskaoalaska 5 лет назад +1

      Well said. This goes for a lot crash course videos.

  • @sahinyasar9119
    @sahinyasar9119 5 лет назад +2

    maybe we should try gene edit on human where a small island nation to understand how to use crispr
    You know if we wont try we never gonna understand and maybe we can create new species

    • @magnuspeacock5857
      @magnuspeacock5857 5 лет назад

      I that need an molecular green body and in old my gene too!

    • @sahinyasar9119
      @sahinyasar9119 5 лет назад

      @@magnuspeacock5857 exacly we need a nation as big as island for who are biohacker and who want use crispr on their next gen make stick together for not make their gene escape to countinent
      Than start research for create advance civilization by crispr and other tech

    • @ohtheblah
      @ohtheblah 5 лет назад +1

      @@sahinyasar9119 all your base pairs are belong to us

    • @sahinyasar9119
      @sahinyasar9119 5 лет назад

      @@ohtheblah Well. I think im okay with that because everything for humankind of future

  • @indianstudywithme8255
    @indianstudywithme8255 5 лет назад

    Genetic engineering 😂

  • @ferencgazdag1406
    @ferencgazdag1406 5 лет назад

    If i could make a designer baby, i would make it's gonads have my genome, and have it's body have some perfect genome, for maximizing survival and reproduction.

  • @StephenGillie
    @StephenGillie 5 лет назад

    Life is indistinguishable from sufficiently advanced technology - adapted from Arthur C Clarke.

  • @nmarsh8260
    @nmarsh8260 5 лет назад

    First to like and comment # early squad

  • @Dreamwave1996
    @Dreamwave1996 5 лет назад

    It's an interesting take you have at 11:35
    When new TV's or new phones come out, that's also exclusively for wealthier before the poorer. Everything is a resource, and wealthier get first bite at it. That's nothing new ever in history of humanity. It's a bit odd you're painting that as such a negative thing.

  • @titojayboy601
    @titojayboy601 5 лет назад

    This s creepy n unnatural...