Thank you for uploading the season 2 compilation of Don't Rush Breast cases. The cases you discussed are unique and you explained is very well how to approach such cases. Following in twitter for season 3 cases.
thanks a lot. I have just came across your channel and found it really useful. I hope you make more videos covering diagnostic approaches, DDs, problems and their solutions.
Your presentations are great and very helpful! One topic about which I'd like to see a presentation is the grading of DCIS. Intermediate versus low grade is where I struggle the most. Thanks!
Here is another topic, 2+ vs 3+ IHC for her2. there seems to be very little out there as images to give visual guidance. translating the guidelines to what we see on the slide is quite imprecise. I very much agree with your comment that we need to evaluate the controls when looking at another lab's her2 stain. It seems like every 3+ given as an example is so dark it is almost black. The one example I have found from a journal article which shows examples of 2+ and 3+ shows a weak 2+ and an extremely dark 3+ so that is not much help. The struggle, of course, is between 2+ and 3+ because that makes the difference in whether they give herceptin. Thanks again!
Yes that is a difficult thing to do, and one of the more practical questions I've received. I'll try to compile a lot of Her2 cases with corresponding SISH to see what I can put together!
what do you think of nuclear staining for her2 IHC? do you believe it is a strong indication the tumor is actually from a site other than breast? I have noticed this 3 times that I can recall. Thanks!
Im not a pathology student but rather just diagnosed with spindle cell carcinoma and i can't find anything on this type. Im awaiting more testing from mayo clinic in Minnesota because unfortunately my local lab didn't have the equipment to do further testing. Im pleading with anyone who can educate me about this. I truly appreciate your insight and I have a positive approach to this but I need educated as i don't see my surgeon until June 23rd.
miss kitty spindle cell carcinoma and solitary fibrosis are two completely different diagnoses. I’d highly recommend you talk to your surgeon/oncologist and inquire about the pathology report.
Hi how to report a pure invasive lobular carcinoma in a core biopsy? Is it appropriate to call it invasive mammary carcinoma with lobular features or can one call it invasive lobular carcinoma directly? Thanks..
If you have pure infiltrating lobular carcinoma in a core biopsy then I call it infiltrating lobular carcinoma. The only time I mention lobular features is if I clearly have an area of ductal differentiation elsewhere.
Thank you Alex,, i started reporting breast cores and this 25:10 always confused me! I have much more clarity now! Looking forward to more sessions.
I am looking for the season 3. Your presentation is outstanding.
Thank you for uploading the season 2 compilation of Don't Rush Breast cases. The cases you discussed are unique and you explained is very well how to approach such cases. Following in twitter for season 3 cases.
thanks a lot. I have just came across your channel and found it really useful. I hope you make more videos covering diagnostic approaches, DDs, problems and their solutions.
beautiful cases and discussion...thank u so much...u make breast path look so easy !
Your presentations are great and very helpful! One topic about which I'd like to see a presentation is the grading of DCIS. Intermediate versus low grade is where I struggle the most. Thanks!
km cginlp that’s a great idea. I’ll try to dig up some examples
Thank you very informative and helpful
can you upload a lecture about papillary lesions of breast? approach in various types of biopsies..
Definitely! Working on an in-situ lecture now, but will put that on the list
good cases
Very nice
Here is another topic, 2+ vs 3+ IHC for her2. there seems to be very little out there as images to give visual guidance. translating the guidelines to what we see on the slide is quite imprecise. I very much agree with your comment that we need to evaluate the controls when looking at another lab's her2 stain. It seems like every 3+ given as an example is so dark it is almost black. The one example I have found from a journal article which shows examples of 2+ and 3+ shows a weak 2+ and an extremely dark 3+ so that is not much help. The struggle, of course, is between 2+ and 3+ because that makes the difference in whether they give herceptin. Thanks again!
Yes that is a difficult thing to do, and one of the more practical questions I've received. I'll try to compile a lot of Her2 cases with corresponding SISH to see what I can put together!
Thank you very nice
what do you think of nuclear staining for her2 IHC? do you believe it is a strong indication the tumor is actually from a site other than breast? I have noticed this 3 times that I can recall. Thanks!
Im not a pathology student but rather just diagnosed with spindle cell carcinoma and i can't find anything on this type. Im awaiting more testing from mayo clinic in Minnesota because unfortunately my local lab didn't have the equipment to do further testing. Im pleading with anyone who can educate me about this. I truly appreciate your insight and I have a positive approach to this but I need educated as i don't see my surgeon until June 23rd.
I should say of the breast
Final pathology report says solitary fibrosis tumor of breast which is uncommon is all i can find
miss kitty spindle cell carcinoma and solitary fibrosis are two completely different diagnoses. I’d highly recommend you talk to your surgeon/oncologist and inquire about the pathology report.
@@adamronMD i have the pathologist report and its solitary fibrosis tumor in my left breast and yes its malignant.
Hi how to report a pure invasive lobular carcinoma in a core biopsy? Is it appropriate to call it invasive mammary carcinoma with lobular features or can one call it invasive lobular carcinoma directly? Thanks..
If you have pure infiltrating lobular carcinoma in a core biopsy then I call it infiltrating lobular carcinoma. The only time I mention lobular features is if I clearly have an area of ductal differentiation elsewhere.