We Just “Cured” Type 1 Diabetes!

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  • Опубликовано: 22 дек 2024

Комментарии • 10 тыс.

  • @shadowldrago
    @shadowldrago 2 месяца назад +54083

    This is one HELL of a Step 1 if it works consistently.

    • @aazhie
      @aazhie 2 месяца назад +933

      Absolutely.I hope she continues to do well!!

    • @shadowldrago
      @shadowldrago 2 месяца назад +369

      @@aazhie On that, we are of one mind.

    • @Gamerphoenix135
      @Gamerphoenix135 2 месяца назад +438

      The way we should move forward is by making this cheaper and more reliable

    • @shadowldrago
      @shadowldrago 2 месяца назад +120

      @@Gamerphoenix135 This is also true.

    • @Polonium212
      @Polonium212 2 месяца назад +15

      Lol… this is not a step 1. Treatments for type 1 already exist

  • @Antenox
    @Antenox 2 месяца назад +41426

    inb4 insulin manufacturers lobby Congress for increased regulation on non-pharmaceutical treatments

    • @wpsp2010
      @wpsp2010 2 месяца назад +7244

      Either that or the scientists who worked on this all get on a flight that just so happens to crash, while their lab 'accidently' catches fire

    • @coachtaewherbalife8817
      @coachtaewherbalife8817 2 месяца назад +2676

      ​@@wpsp2010Don't fly Boeing.

    • @patrickthebutcher
      @patrickthebutcher 2 месяца назад

      Because alternative medicine doesn't kill enough people every year....

    • @ravenonthecross
      @ravenonthecross 2 месяца назад +1369

      Just make it public info.

    • @Timmycoo
      @Timmycoo 2 месяца назад +1365

      Can't I just live in my own little fantasy world where people are good natured.. lol :(

  • @kelsidettlaff84
    @kelsidettlaff84 2 месяца назад +4414

    My dad just passed away from type 1 diabetes this summer. He was only 49. Cannot overstate how important this is. Thank you to the researchers out there potentially saving lives

    • @Itz_Zagha
      @Itz_Zagha 2 месяца назад +80

      I'm sorry for your loss 🙏

    • @Sunny-Smiles1234
      @Sunny-Smiles1234 2 месяца назад +54

      I’m sorry for your loss. My husband has type 1… may I ask when was your dad diagnosed? How man years did he live with it?

    • @icutoffmyleftwing7190
      @icutoffmyleftwing7190 2 месяца назад +22

      ​@@Sunny-Smiles1234😢😢😢 may God bless you. You and your husband are in my prayers.

    • @Spade948
      @Spade948 2 месяца назад +10

      Sorry for your loss

    • @absinthealice
      @absinthealice 2 месяца назад

      I'm very sorry for your loss. Sincere condolences. 🫂❤️‍🩹

  • @Xillios
    @Xillios Месяц назад +729

    Once the news dies down after 1-2 years, either the researchers or the subject will mysteriously dissappear or self-delete themselves. They basically just told the entire industry they have 5 years to "take care of the problem."
    R.I.P. in advance.

    • @lisah.7640
      @lisah.7640 20 дней назад +32

      yeah because diabetes type 2 isn't going to be number one of mondern illnesses and insulin isn't already rare and not always in stock. not to forget that most countries don't have prices like the US does. I need to buy the insulin for my cat from my own money (no incurance no money from government or something) and I pay 40 Euro for what my human friend needs for half a year (as a human she doesn't have to pay for the insulin)...

    • @JustAGooseman
      @JustAGooseman 20 дней назад

      @@lisah.7640 Insulin ISNT rare. Its made from yeast and bacteria's that are extremely common, and there are methods to make literal hundreds of gallons of the stuff in a week. But why would the pharma companies do that if they can just sell it to you for hundreds of dollars a litre lol.

    • @PRO_.G4M3R666
      @PRO_.G4M3R666 15 дней назад

      @@lisah.7640Yea my human friend sometimes goes Ape shit & I gotta ‘rehumanize’ her. Government said something about pet fees ain’t applicable for human friends but ion know😂.(im jokin btw)

    • @mikewebb7807
      @mikewebb7807 14 дней назад

      ​@lisah.7640 I think I speak for all Americans that is rather have to pay 40 euro for 6 months of medication than a single payment in the US

    • @gameplayer3050
      @gameplayer3050 13 дней назад

      I mean, theoretically, that might be true.
      However, there isa reason why it is only viable for Type I.
      Type I is a genetic disorder and only 10 % of all diabetes patients are Type I. The overhwelming majority are Type II. And Type 2 works completely differently. Meaning that this form of therapy would not work at all.
      + this is probably not something that will work for everyone. The only question is if the pharma industry is willing to take a potential hit of a few millions tops. But I would not be surprised.

  • @djwolfane
    @djwolfane 2 месяца назад +2494

    Being able to essentially "reset" a cells differentiated state will go far beyond just type 1 diabeties and it this pans out sets researchers up for rapid cellular therapy for MANY of our current chronic diseases

    • @mythreepants
      @mythreepants 2 месяца назад

      A lot of near term promise for exocrine/endocrine or bleeding disorders. If the body doesn't make the thing, tell cell to make the thing and stick them in (assuming an autoimmune reaction doesn't redevelop in cases like Type ai diabetes). I'm actually working on a project reprogramming stem cells into alveolar lung cells (for drug/genetic testing purposes mostly). If we were to use them clinically for lung diseases, we'd have to find a way to make the new cells replace the damaged/fibrotic regions. A lot more difficult

    • @Accelle-kx8yh
      @Accelle-kx8yh 2 месяца назад +73

      I just also think that we opened up something that we could use to heal all kinds of illnesses …re-programming is one of the keys.

    • @piterpraker3399
      @piterpraker3399 2 месяца назад +47

      This is old tech. I initially started into stem cell research with this in mind - then I realized that they just really liked using fetal cells, so I got out. Cost effectiveness is the bottom line.
      Rest assured, the masses are likely a decade away from seeing this. It will be reserved for the elite.

    • @happygolucky9004
      @happygolucky9004 2 месяца назад

      ​@@piterpraker3399I completely agree. These are well known methods. Not to mention type 1 diabetes is an autoimmune disease. So the patients immune system will keep killing of the transplanted cells. This is hardly new or a cure.

    • @brigidtheirish
      @brigidtheirish 2 месяца назад +32

      @@piterpraker3399 Yeah. The whole "we have to use fetal stem cells" line always sounded like an excuse to me. Adults have stem cells, too. From what I've heard, they're also a lot more stable than fetal stem cells.

  • @kevincobb6331
    @kevincobb6331 2 месяца назад +23072

    Great! Until pharmaceutical companies lobby to kill competition for this treatment and jack the price up to $500K per dose

    • @lrom5445
      @lrom5445 2 месяца назад +794

      Type 1 is only like 6% of the diabetic population. True, they are forced to spend a bunch, but the real money for those companies is in the GPL-1 meds that non-diabetics are scrambling to take for weight loss.
      They might try to bury it, but insurance companies will also have reason to lobby to get it approved since they end up paying for those meds usually.

    • @garrnk
      @garrnk 2 месяца назад +379

      Only 500k? That's cheaper then 80 years of insulin pumps glucose readers insulin needles alcohol wipes and other supplies Like emergency supplies

    • @diegopereira9452
      @diegopereira9452 2 месяца назад +224

      Wow, imagine free and universal health care

    • @crazycutz8072
      @crazycutz8072 2 месяца назад

      Must be amerucan companies .. in Europe the insulin meds are cheap as pasta

    • @thejasminedragonmerchant6843
      @thejasminedragonmerchant6843 2 месяца назад +47

      Please don't jinx it, this could be so wonderful if it works ☹️

  • @Drewdiabetes
    @Drewdiabetes 2 месяца назад +5125

    Thank you for reporting on this, Kyle!
    Signed, a very tired type 1 diabetic

    • @lourias
      @lourias 2 месяца назад +63

      My friend died in July 2024 from over 40 years of Type 1 diabetes complications.
      I am a surgically induced diabetic, wishing islet cell transplantation was way past experimental trials when most of my pancreas was removed. So much of it was removed that it is now the size of a golf ball.

    • @brandonwirtz2308
      @brandonwirtz2308 2 месяца назад +41

      A step for type one is a step for all diabetes. My brother died from type one several years ago, and I died from type 2 about 6 years ago. (Heart attack, died, came back. 45 min CPR, 3 weeks coma.)

    • @JoaoOstroski420
      @JoaoOstroski420 2 месяца назад +21

      same here brother, hopefully some day we can get rid of this god damn condition, if the capitalists who are profiting off of our suffering allow it, of course.
      i just wanna eat some ice cream after lunch and take a nap not having to worry about this shit >:/

    • @ExtantPerson
      @ExtantPerson 2 месяца назад +13

      Also signed, another very tired T1

    • @snaifhassnan6348
      @snaifhassnan6348 2 месяца назад +2

      717

  • @erykross
    @erykross Месяц назад +10

    Honestly so damn cool to hear! My brother in law has had it his whole life. Would be amazing to see him be free of it.

  • @ripperdjak6224
    @ripperdjak6224 2 месяца назад +12022

    Now remember kids, none of the researchers have self deleting thoughts.

    • @Modioman69
      @Modioman69 2 месяца назад +1433

      Right, next day in the news : “The researchers all sadly passed away at the same time, they all coincidentally slipped and fell down the same flight of stairs at the same time.. completely accidental and un related to their research.. details at 11 stay tuned.”

    • @TigerFucker
      @TigerFucker 2 месяца назад

      are you their therapist or how do you know?

    • @monadiloka
      @monadiloka 2 месяца назад +834

      @@Modioman69 And they accidentally destroyed/hid their research materials while dying.

    • @fucking_smooth
      @fucking_smooth 2 месяца назад

      I know; the government needs to stop suiciding smart people, who realistically, are the people who’ll ferry us into the future.

    • @christopherlee9026
      @christopherlee9026 2 месяца назад +339

      I mean what's far more likely to happen here is that this gets bought out and then we never hear about it again, stuff like that happens all the time, companies buying their competitors out and then shut them down.

  • @maxwelltheluxray861
    @maxwelltheluxray861 2 месяца назад +5949

    Big pharma around the corner making it's price at 5k each treatment with shitty insurance covering it

    • @hanzzel6086
      @hanzzel6086 2 месяца назад +128

      First: this is Chinese study. Second: (assuming you are in the U.S) Then get rid of your shitty nonfunctional "healthcare" system and take a page from Europe (not Canada, our healthcare system *is* better than yours, but *the* laughing stock of Universal Healthcare). Just surgeries alone would be between 40-90% cheaper, never mind stuff like Insulin (iirc, it's currently $20 CA, that's closer to $15 US). You could cut the money expenditure in healthcare in *half* , and still have more free money to put where it's needed!

    • @kaps_k8742
      @kaps_k8742 2 месяца назад +224

      ​@@hanzzel6086 ooh yeah good one there, that guy should just remove the healthcare system in his country, im sure thats helpful!!!

    • @jasonbfhfj8132
      @jasonbfhfj8132 2 месяца назад +61

      @@hanzzel6086yeah because the UK’s “free” healthcare isn’t crumbling. Mark Cuban proved private healthcare works when he made his own pharmaceutical company and didn’t take insurance. He sells affordable pharmaceutical. Wow imagine that. A world where government isn’t necessary.

    • @railfandepotproductions
      @railfandepotproductions 2 месяца назад

      ​@@jasonbfhfj8132tell that anyone in Europe I dare you

    • @chkensammich
      @chkensammich 2 месяца назад

      ​@@hanzzel6086 Nahhhh the US is cooked bro it's going to be a sh*thole forever
      It's going to continue to be the worst county in the Americas to live in (after Venezuela) til the end of time

  • @dovebair
    @dovebair 2 месяца назад +1370

    Not only is this an amazing medical discovery, that will open major doors for millions of people ; but this will be a gigantic step forward in the survivability of disasters. The logistics around keeping insulin active are a nightmare in a chaos scenario.

    • @PieBoy4242
      @PieBoy4242 2 месяца назад +28

      You should see the calls for Epi pens from the people evacuated after the hurricane. They all went straight into Southern Yellow Jacket territory.

    • @GogiRegion
      @GogiRegion 2 месяца назад +22

      If this goes well, it would be really cool to see organizations that go into areas with upcoming disasters to help give this treatment so people are more prepared.

    • @badidea6034
      @badidea6034 2 месяца назад +21

      There was at least one reported case of a young Palestinian man with diabetes type 1 dying due to lack of access to insulin. It broke my heart as my brother has diabetes type 1, I can't imagine how scary and painful his last moments must've been💔

    • @bruhyou4305
      @bruhyou4305 2 месяца назад +9

      every year there's a new article claiming that they cure diabetes, this isn't new, nothing ever changes

    • @TwoPartyIllusion
      @TwoPartyIllusion 2 месяца назад

      ​@@bruhyou4305And nothing ever will, too much $ to be made!☠️

  • @Corinneleightaylor
    @Corinneleightaylor 11 дней назад +12

    Tysm for addressing type 1. I feel everything is always about type 2. ❤

  • @jameji_phd
    @jameji_phd 2 месяца назад +1228

    Even if she does only produce enough for 5 or so years, imagine just having to get a treatment like that every 5 years, instead of having to worry about how much insulin you have *all the time*.
    Even if it doesn't end up a permanent "cure", this is GROUNDBREAKING.

    • @k.elysium6819
      @k.elysium6819 2 месяца назад +51

      I imagine the procedure will be extremely expensive in the US. Probably more than taking insulin. At least at first.

    • @adamc4951
      @adamc4951 2 месяца назад +27

      It's not, the patient had to be on immunosuppressants, which have worse side effects than the type 1 diabetes. Making beta cells from stem cells is the easy part.

    • @TheAdAarora
      @TheAdAarora 2 месяца назад +13

      On the other hand you're now running into a potential issue where you'll end up with an insulin-deficiency because you didnt get your ( hopefully mandatory at that point ) check-up to catch when those cells stop producing enough insulin

    • @_ch1pset
      @_ch1pset 2 месяца назад +13

      there's this concept called a "functional cure" which usually pertains to controlling a viral infection after treatment, but I imagine that it might apply here, where there is still some underlying risk of relapse, but otherwise, it is controlled without continued treatment.

    • @adamc4951
      @adamc4951 2 месяца назад +2

      @@_ch1pset Yes functional cure is used in T1D to refer to a future more advanced version of the current hybrid-closed loop systems where an algorithm automatically adjusts insulin infusion rates based on readings from a continuous glucose monitor. Currently they require a lot of user input still, but with faster insulins the gap is closing.

  • @eerole
    @eerole 2 месяца назад +783

    The longer you live with T1D the less excited you get over news like this. I’m immediately asking if they’ve got a way to suppress the autoimmune response that could attack the cells, etc. But maybe this time is the charm.

    • @d.sm.4146
      @d.sm.4146 2 месяца назад +104

      This ^... Honestly whatever Kyle is talking about sounds like it's only addressing the symptoms that is called diabetes, not the disease itself, the auto-immune deficiency.

    • @alastorlapid2365
      @alastorlapid2365 2 месяца назад +29

      That was exactly what I was thinking. I guess immunosuppressants could possibly work, but I'm not sure.

    • @willklemp6900
      @willklemp6900 2 месяца назад +54

      Why would her body reject her own cells? Im sorry, I'm just genuinely curious, and don't understand

    • @blairmacdonald9632
      @blairmacdonald9632 2 месяца назад +48

      You got it, she got this treatment because she's already taking immunosuppressants for a liver transplant.

    • @wells13
      @wells13 2 месяца назад +21

      how many t1 diabetics would want to charge from using insulin (and many people have pumps now) to having to take immunosuppressant drugs

  • @nathanforrest3483
    @nathanforrest3483 2 месяца назад +960

    Type 1 diabetic here. This is awesome but I can't wait another 15 yrs.

    • @raynjpg
      @raynjpg 2 месяца назад +75

      type one here too, still waiting for "artificial pancreases"

    • @nathanforrest3483
      @nathanforrest3483 2 месяца назад +13

      @@raynjpg yeah. I'm sure the technology is out there.

    • @csatt13
      @csatt13 2 месяца назад +12

      Hello, brothers. I would be shocked if this kind of thing was widely available before I'm an old(er) man, but we can hope.

    • @Hashslingingslasherrrrrr
      @Hashslingingslasherrrrrr 2 месяца назад +1

      @@nathanforrest3483the elites have all the cures to everything

    • @TheBluePhoenix008
      @TheBluePhoenix008 2 месяца назад

      ​@@raynjpg be the change you wanna be, become a doctor lol

  • @ewhays
    @ewhays Месяц назад +2

    I worked in a lab as a student, isolating the beta cells of murine and ratine pancreata about 10 years ago. It was fascinating and finicky work. Good job science!

  • @bkingski1125
    @bkingski1125 2 месяца назад +3438

    Why isnt this all over the news? This girl should be on every talk show. These scientists should be on magazine covers!

    • @Zankyo137
      @Zankyo137 2 месяца назад +702

      a few reasons:
      -It has worked on one subject so far
      -there is no know timeframe for the treatment: will it last? or will she revert back to hacving T1D? (this is the reason for the 5 years)
      -the treatment need to be reproducable multiple time in multiple enviroment

    • @rotamrofsnart
      @rotamrofsnart 2 месяца назад +23

      It's in-vitro

    • @slipperycatfish9817
      @slipperycatfish9817 2 месяца назад

      Because 1 patient cured isn't a cure, esp when it's temporary. It's at best a treatment. It also won't be helpful for 95% of diabetes patients because they don't have type 1

    • @MihzvolWuriar
      @MihzvolWuriar 2 месяца назад +175

      @@Zankyo137 All those arguments goes out the window when the science is favorable to the news agenda, even if this isn't against their agenda, it's not positive enough to show up there.
      Yes this should be in the news, in the same exact way it is here, a tale of a promising future for everyone.
      Remember, nowadays news treat science the same way the USSR treated it, if it's positive to their world view, share, if it's neutral or negative, it never happened.

    • @Zankyo137
      @Zankyo137 2 месяца назад +70

      @@MihzvolWuriar i'm not american, elsewere science is treated better than that in the news.
      so you argument is not valid

  • @thedepression950
    @thedepression950 2 месяца назад +604

    PLEASE spread awareness that this technique is not being used yet. Please tell people who need this to not go to hospital for this. It is really starting become a problem for the nurses and the doctors across the world. People are demanding that they want the same thing even if it is experimental. Doctors are needed to be trained to do this properly. There is a reason why this is experimental.
    The full story (as far as I know):
    The woman had kidney transplant and was using immunosuppressants. And the doctors went "since she's already using immunosuppressants why don't we transplant a pancreas her too" since she's type 1 diabetic and her pancreas is not working properly. But even while she's using immunosuppressants her body rejected it so they had to remove it. Now without a pancreas, they resorted to this. I dont know where they got the cells exactly but they made the root cells and injected into her abdomen. After a while, they saw a lump of flesh acting as a pancreas producing the insulin she needed.
    Edit: the lump of flesh part is my speculation because it was not mentioned how she was producing insulin in the article.

    • @LumTheAlien
      @LumTheAlien 2 месяца назад +27

      Do you know the name of the paper of this research I would love to read it.

    • @Agagnier
      @Agagnier 2 месяца назад +6

      Thank you.

    • @mason6883
      @mason6883 2 месяца назад +17

      They should be demanding it. The pace of development is far to slow. Why should we wait 5 year for a single case study before starting a wider trial?

    • @Headloser
      @Headloser 2 месяца назад

      I though the replanted cells were put into her liver and they started produce Insulin

    • @thedepression950
      @thedepression950 2 месяца назад +1

      @@mason6883 because if there is a problem with the root cells they plant, many people will die regardless of their genetic variety. 1 and 1000 people is not so different right now. The only difference is how many lifes are at stake if something goes wrong.

  • @Wrendition
    @Wrendition 20 дней назад +2

    A once every 5 year treatment is still incredible. This is amazing!

  • @biff64gc
    @biff64gc 2 месяца назад +4927

    One MASSIVE detail you didn't mention is the patient that was "cured" was on immunosuppressant drugs from a previous liver transplant. The main issue with type 1 is the immune system kills the cells that produce insulin.
    It's cool that they were able to program cells in this way, but until they can prove an active immune system won't just kill the new ones we should remain skeptical.

    • @Whitewing89
      @Whitewing89 2 месяца назад +183

      Is that what causes it? An autoimmune response? All i remember hearing when i was diagnosed was that they didn't know the cause.

    • @decayingsun5798
      @decayingsun5798 2 месяца назад +413

      That's probably why they want her to continue under observation for five years. That'll probably be enough time to get off the immunosuppressants (depending on the reason she was on them in the first place) and have any lingering stuff from that cycle out. And then, of course, keep producing insulin afterwards.
      If immunosuppressants are required for the treatment to work I think that'll just be another step in the process, and not so big a deal.

    • @peterdefrankrijker
      @peterdefrankrijker 2 месяца назад

      @@Whitewing89They don’t know what _triggers_ the autoimmune reaction, but after that, they know _exactly_ what happens.
      If they could discover the trigger, they would also be able to block it. Perhaps even make a DMT1 vaccine. But alas.

    • @LondonHomerWambeam
      @LondonHomerWambeam 2 месяца назад +207

      @@Whitewing89you are thinking of type 2. The cause of type 1 is well understood, though what triggers the autoimmune reaction is not.

    • @LondonHomerWambeam
      @LondonHomerWambeam 2 месяца назад +57

      @@decayingsun5798why would she be able to go off immunosuppressants after five years? The body would still attack any insulin producing cells, the immunosuppressants aren’t needed because they are transplants but because it’s an autoimmune disease.

  • @RI-Kirishikai
    @RI-Kirishikai 2 месяца назад +247

    I lost my little cousin to diabetes. Im sure she wouldve been proud to hear all this progress coming in. I miss her every day man this makes me really fucking happy

    • @ManiyaVinas
      @ManiyaVinas 2 месяца назад +1

      From which country are you

    • @RI-Kirishikai
      @RI-Kirishikai 2 месяца назад +6

      @@ManiyaVinas usa

    • @blazesalamancer8767
      @blazesalamancer8767 2 месяца назад +4

      ​​@@ManiyaVinasThe healthcare system is so incredibly fucked here, in fact every single system in the US is broken beyond repair

    • @dedompler
      @dedompler 2 месяца назад

      ​@@blazesalamancer8767
      the systems were never designed to work, only to operate at thinly veiled minimum viability in order to placate the population into believing we have "systems" that actually do anything besides funnel billions of dollars to a few hundred people.

  • @submerged7640
    @submerged7640 2 месяца назад +2056

    Wait till big pharma hears about this

    • @glenngriffon8032
      @glenngriffon8032 2 месяца назад

      Yeah the American insulin cartel is gonna be working to stomp this down

    • @watcherofwatchers
      @watcherofwatchers 2 месяца назад +29

      Who do you think is paying for this research?

    • @trevor_kelley
      @trevor_kelley 2 месяца назад +133

      ​@@watcherofwatchers Our taxes probably.

    • @Lily8Numbers
      @Lily8Numbers 2 месяца назад +43

      ​@@trevor_kelleyif it's at an university, students maybe

    • @watcherofwatchers
      @watcherofwatchers 2 месяца назад +78

      @@trevor_kelley Actually, no. The Chinese government, as this is the result of a Chinese university study.
      Had this been a US-based study, it likely would have been funded by "big pharma," because that's who funds most treatment research like this.
      The pharmaceutical industry gets bad press, sometimes deserved and sometimes not, but they are responsible for drugs and treatments that save lives every day.
      There would be substantially less treatment options without the profit motive.

  • @AmazingEmotion
    @AmazingEmotion 21 день назад +1

    Keep moving forward... Thank you for doing the work...
    I am listening...
    Again thank you

  • @thesentry3497
    @thesentry3497 2 месяца назад +851

    Man, R.I.P to the researchers and condolences to their families.

    • @alphatonic1481
      @alphatonic1481 2 месяца назад +17

      And everyone in this comment section.

    • @purplestatic4917
      @purplestatic4917 2 месяца назад

      the researchers are from china and are sponsored by their government, which means i doubt the cia is gonna snipe them

    • @mspaperlapap7706
      @mspaperlapap7706 2 месяца назад +8

      What??

    • @forgotten893
      @forgotten893 2 месяца назад

      @@mspaperlapap7706 Big Pharma is going to either A) off the researchers, or B) lobby against this, causing the researchers to off themselves.

    • @arkdoesstuff7362
      @arkdoesstuff7362 2 месяца назад +29

      There are prolly 5 hitmen at their location claiming they commited suicide by sniper at the back of the head. 😢

  • @St3hI
    @St3hI 2 месяца назад +412

    My Grandfather was type one diabetic, he died just last year. I wish he could have been around to see this.

    • @Blu3s7reak
      @Blu3s7reak 2 месяца назад +8

      How old was he?

    • @rogeliomolinero2498
      @rogeliomolinero2498 2 месяца назад +5

      You know same thing wit my father, only thing was he had type 2, wish he could have seen this aswell

    • @zeronenine-randomguy
      @zeronenine-randomguy 2 месяца назад

      Don't you get type 1 through genetics? Watch out

    • @happygolucky9004
      @happygolucky9004 2 месяца назад +1

      Why? This method isn't new and it isn't a cure or even a good therapy. Type 1 is an autoimmune disease and all the grafted cells are killed off by the host immune system.

    • @DangerSquiggles
      @DangerSquiggles 2 месяца назад

      @@rogeliomolinero2498 This treatment would not help a person with type 2 diabetes - they make enough insulin, the other cells int he body are just resistant to the effects of it.

  • @lrom5445
    @lrom5445 2 месяца назад +420

    From what I've read, this was a big step for the more prevalent type 2 as well. The other person, a 59 year old male, that was essentially cured in a similar study was type 2. There is a question of whether the body rejects these long term, and it's a chinese study, so it's yet unknown if we'll see progress in the US on this.

    • @GogiRegion
      @GogiRegion 2 месяца назад +17

      I wonder if in the future we’ll be able check for pancreas cell transfer compatibility the same way we do for transplant surgery compatibility.

    • @AaronAlso
      @AaronAlso 2 месяца назад +19

      Type 2 has been curable for decades.

    • @theballindinosaur
      @theballindinosaur 2 месяца назад +24

      Type 2 is virtually curable, but they don't like that term because it implies an easy mostly mediated cure through medicated recovery. But most of the time it's reversible, just requires changes to lifestyle. People suffer through due to the inability to make those necessary changes, whether that be diet or inactivity. Honestly, like genuinely, it's a shame that's how most people see diabetes. It's self induced diabetes that could've been avoided most of the time for type 2, type 1 is purely genetic. It's not because you ate too much cake and your pancreas went oh no, that's alot of sugar. Problem is the average person doesn't know anywhere near enough about the human body to understand even the most basic disorders and diseases. The amount of people who don't understand the difference is astonishing, they just think "if you control your diet you'll get better", or the obligatory "you should stop eating so much sugar" or "aren't you a diabetic" when they see you eating something mildly sweet while your bloodsugar isn't even reading anymore it's so low. People are fucking stupid, surprisingly stupid and incredibly ignorant of these things, and now they only associate diabetes with morbidly obese people because people are eating absolute shit day in day out. One is an autoimmune disease, the other, or second is eating far more than your functioning pancreas can keep up with. Two is reversible, with work of course, one is forever, depending on where this research goes. I'd rather have the opportunity to not be a diabetic then really most other things in life, countless type 1 diabetics agree with that sentiment and some are even envious that all it takes the type 2 are diet control and exercise. Thinking, if only it were that easy. Most of us do that already just to survive and afford insulin. Alot more costly when your having to take a metric f-ton to overcome insulin resistance from overuse. We need to make new terms to differentiate. Sure, we're both sugar bloods, but mine wasn't by choice.

    • @JoeProKill
      @JoeProKill 2 месяца назад

      @@theballindinosaurshould be noted that type 2 is not curable, only reversible to a degree. You can mitigate the damages and potentially no longer require insulin through lifestyle changes but it will always be there and any change in lifestyle could easily make it reappear

    • @Swagbastian
      @Swagbastian 2 месяца назад +1

      ​@@theballindinosaurTRUE THO

  • @nikki.londonuk6881
    @nikki.londonuk6881 21 день назад +1

    My 17yr old son got diagnosed with Type 1 diabetes at 6 yrs old and is both on the Dexcom G6 and omnipod,so I’ll definitely be keeping my eye on this🤗

  • @christianokami2220
    @christianokami2220 2 месяца назад +292

    I pray to God this is pushed further. My sister is type-1, and has survived some absolutely scary hospital stays.

    • @MonkeyJedi99
      @MonkeyJedi99 2 месяца назад +6

      I had a friend who lost most of his eyesight, then developed skin nodules, then lost a leg and eventually his life to type1 diabetes.
      When he was first diagnosed at pre-school age, the first doctor to talk to him when he woke out of his (first) diabetic coma told him, "You shouldn't be alive!"
      -
      He made that doctor a liar for almost four decades.

    • @maxwellanderson8412
      @maxwellanderson8412 2 месяца назад

      Have had T1 for several years, never had anything close to this happen. This only happens if you literally never take your insulin. Darwin Awards for T1Ds who end up dying because of it.

    • @badidea6034
      @badidea6034 2 месяца назад +2

      My brother has had a lot painful injuries due to hypos, including a broken nose, broken teeth, a dislocated shoulder and more. It's hard to regulate your own blood sugar every single day, it can go right for months but it only takes one mistake for a bad outcome to happen. Thank God he hasn't been in a fatal accident or has any health complications. He lives very healthy and goes to the gym every day. I pray your sister stays safe and happy❤️

    • @FB94121
      @FB94121 2 месяца назад +5

      ​@@MonkeyJedi99mate your friend isn't taking care of himself. I've had type 1 for over 30 years and no issues at all. You just can't be lazy about taking insulin

    • @MonkeyJedi99
      @MonkeyJedi99 2 месяца назад

      @@FB94121 You might have missed the past-tense in my tale.
      As for him not caring for himself, he had periods where insurance kept refusing him coverage, some bouts of severe depression when he let his self-care drop, and such.

  • @kernium
    @kernium 2 месяца назад +994

    As someone whose grandmother died of Diabetes, I can't help but shed a tear at this info.
    Diabetes, like Cancer, was always considered like one of those "uncureable" diseases and I'm glad the World got proven wrong.
    I really hope this method works, both for this woman, and for the World.

    • @jacobjoaquinignacio
      @jacobjoaquinignacio 2 месяца назад

      Yes. Nothing is truly “uncurable.” It’s just that these people in control of pharmaceutical companies know that they will lose money if a cure is found.

    • @kaynor1260
      @kaynor1260 2 месяца назад +12

      Hopefully methods like this can be used to treat things like hypothyroidism, it's nothing life threatening like diabetes or cancer but it's still not great

    • @CoIdHeat
      @CoIdHeat 2 месяца назад

      Considering how easy and effective it is nowadays to treat Diabetes or AIDS, both being diseases that where a death sentence only 30 years ago, its crazy how fast medicine has evolved. Don’t get me even started about the groundbreaking use of Penicillin since the 40s or the fact that ICUs only exist since the 70s and people who nowadays lie on an ICU and might be saved were usually doomed to die before the 70s.

    • @rampagepotato4307
      @rampagepotato4307 2 месяца назад

      The hardest diseases to cure are those that our bodies consider as normal. Cancer? That's just your own cells going a little bit freaky. Diabetes? Cells that's perfectly normal except they actually lacked an arm and a leg if you look closely. It's like our brains can't do shit to a body it literally controls so it decided to do use external force instead 😂

    • @THTB_lol
      @THTB_lol 2 месяца назад

      @@kaynor1260 would it work for pseudopseudohypoparathyrodism as well

  • @kwith
    @kwith 2 месяца назад +153

    As a type 2 diabetic this makes me happy! Glad those with type 1 have this bright light going for them. Hopefully this works out and can be a huge benefit to millions!

    • @TheBluePhoenix008
      @TheBluePhoenix008 2 месяца назад +2

      To my knowledge, both have the same issue, little to no insulin production. Why can't type 2 be treated with this

    • @kwith
      @kwith 2 месяца назад +9

      @TheBluePhoenix008 they are a little bit different. Type 1 your body basically stops making it and type 2 your pancreas makes less which causes your body to be less efficient in using insulin.
      I could see it maybe working for type 2 but I would think type 1 is the "worse" of the two. I use that word loosely because they are both not good. So if they are getting treated that's awesome.

    • @TheSeranath
      @TheSeranath 2 месяца назад +7

      ​@@kwith my understanding of type 2 was that your body still produces it, but has started to develop immunity to your own insulin, so you need more and more of it?

    • @kwith
      @kwith 2 месяца назад +1

      @TheSeranath yea your pancreas doesn't produce as much and that reduced amount causes your body to become resistant to it and not use it as efficiently.

    • @louisd1827
      @louisd1827 2 месяца назад

      Yall tripping on edge cases of Type-2.
      Leading cause of type-2 diabetes is too much sugar consumption for decades, making the pancreas produce more and more insulin regularly, thereby making all your cells USE more and more insulin, AND slowly adapting your entire body to higher and higher levels of regular blood sugar.
      The very first and important bad thing is this higher sugar level. It ruins your blood vessels, the capillaries first. This increases your risk for all kinds of cardiovascular diseases. In later progress, it also kills the nerves in your extremities cuz they don't get enough blood flow, thereby reducing your ability to feel all sensations in your feet and hands for example and slowly ruining your eye-sight.
      Now some of you talked about reduced insulin efficiency and yes this is the Type-2 Endgame. At some point, if the patient doesn't change their life drastically, it can't be treated with pills anymore and you will need Insulin top-ups.
      The drastic change in life-style and avoidance of sugar in food and drink is the ultimate prevention for type-2 diabetes. Type-1 is unfortunate, type2 is in 90% of cases, just your own fault for eating like shit for years and years.😢

  • @jumperk5627
    @jumperk5627 28 дней назад

    Hey Kyle, you have no idea just how much this means to me.
    I've been a type 1 diabetic for about a decade, and just hearing that we're one step closer to this cure is just absolutely amazing.
    I hope that she will be able to produce insulin within those five years.

  • @cutterlmao
    @cutterlmao 2 месяца назад +234

    Hey Kyle, type one diabetic here. This is truly insane, thank you for covering this so that it’s more widely known. I’m struggling with diabetes, and to hear that there might be an end in sight? It’s amazing. Thank you big man

    • @ekarus4360
      @ekarus4360 2 месяца назад +4

      As we longe dont know why the body attacks it self its unlikely to cure typ 1 sadly

    • @lllllliiillllll
      @lllllliiillllll 2 месяца назад +1

      @@ekarus4360it’s most likely due to the antigens or lack thereof. It’s an autoimmune disease and all of them act in the same way relatively.

  • @xivilaikikira3768
    @xivilaikikira3768 2 месяца назад +478

    Will be following this story. My nephew is type 1 and will love to see this research bear fruit
    Thank you for covering this

    • @aaronmicalowe
      @aaronmicalowe Месяц назад +4

      If this works, type 1 will become more survivable than type 2.

    • @aceman0000099
      @aceman0000099 Месяц назад

      I won't be surprised if the big pharma cartel ends her before we get the 5 year results. They need money

    • @ttgoodywin9212
      @ttgoodywin9212 25 дней назад

      @@aaronmicalowediabetes is plenty “survivable” it just takes management

    • @Filmguy4319
      @Filmguy4319 23 дня назад

      My mother as well

    • @nikki.londonuk6881
      @nikki.londonuk6881 21 день назад

      My 17 yr old is too

  • @Gerdew
    @Gerdew 2 месяца назад +134

    As a T1D this is huge!
    I just really hope the news gets shared more

    • @idiotlyuseful
      @idiotlyuseful 18 дней назад +3

      If you're an american? $600,000

  • @philisophyminuteman
    @philisophyminuteman 2 месяца назад +47

    Been type 1 for 20 years. This stuff never makes it out of whatever phase that makes it disappear.

    • @astraeanova4280
      @astraeanova4280 2 месяца назад

      Totally agree and I've had type1 for 53 years so I've heard of many supposed cures that come to nothing.

    • @Portents-Magic-imagination
      @Portents-Magic-imagination 16 часов назад +1

      True because there’s money in medicines. They don’t want a cure .

    • @Darryl-ci5pv
      @Darryl-ci5pv Час назад

      I have been suffering from type 1 diabetes for over 40 years. I can't wait another 5 years or more..

  • @esperanzazagal7241
    @esperanzazagal7241 Месяц назад +2

    Engineering cells back to a pluripotent stage could be a medical miracle for many conditions. This is a breakthrough.

  • @bookmaster621
    @bookmaster621 2 месяца назад +712

    So sorry to hear about the deletion of everyone working on the project

    • @angelmatiastorres
      @angelmatiastorres 2 месяца назад +8

      😂

    • @benmidnightflame
      @benmidnightflame 2 месяца назад +25

      Gets worse for big pharma. Chinese scientist also used the same process to cure type 2 about half a year ago, also still under testing. The authors originally thought type 1 diabetes possibly wouldn't be cured using this, because the immune system might reject the implanted cells, but were thankfully wrong.

    • @angelogeraldes5776
      @angelogeraldes5776 2 месяца назад +8

      Just a coincidence. Nothing to see here.

    • @thecougarprince
      @thecougarprince 2 месяца назад

      ​@@benmidnightflameit's not gonna get worse for big pharma,it's gonna get worse for them researchers, they dead

    • @libertyforamericanow
      @libertyforamericanow 2 месяца назад

      It's pretty f sad that big pharma doesn't want cures. They want money!

  • @usnairframer
    @usnairframer 2 месяца назад +168

    Thats amazing. I wish my uncle was still around to get the treatment, but im glad it can (hopefully) help others in the future.

    • @clairemann2
      @clairemann2 2 месяца назад +2

      I’m so sorry for your loss love ❤

  • @EmperorZanan
    @EmperorZanan 2 месяца назад +78

    This needs more attention. Thank you for reporting on it.
    Curing Diabetes will help so many people around the world.

    • @V3x0r
      @V3x0r 2 месяца назад

      It's fairly impressive they've already been making the insulin shots out of a modified e-coli virus.

    • @scarsdale7186
      @scarsdale7186 2 месяца назад +1

      I have type 2, I'd love to see something like this for the older set, I'm 64, been T2 for more than ten years. After chemo, it got MUCH harder to keep my glucose levels where they need to be. I guess the cell damage made it worse?

  • @JupiKitten
    @JupiKitten 13 дней назад

    One of my oldest friends just died from type 1 not long ago. He was one of the sweetest humans on this planet and deserved a much longer life then 35 years. I wish they had discovered this sooner.

  • @travishunter8573
    @travishunter8573 2 месяца назад +68

    Hello type 1 diabetic and engineer working on automating the manufacturing of personalized stem cell therapies here, I can't wait for this to be available!

    • @bruhyou4305
      @bruhyou4305 2 месяца назад +3

      when? I've seen articles claiming that they found a cure for like the last 10 years of my life. I don't know man but I just don't believe it anymore

    • @Cheaplinx
      @Cheaplinx 2 месяца назад +2

      the introduction was longer than the statement 😭

    • @travishunter8573
      @travishunter8573 2 месяца назад +1

      @@bruhyou4305 well seems like they are doing human trials so that's a good sign

    • @travishunter8573
      @travishunter8573 2 месяца назад +2

      @@Cheaplinx cause it's relevant

    • @bruhyou4305
      @bruhyou4305 2 месяца назад

      @@travishunter8573 yeah I guess, I just think we shouldn't get our hope up to much

  • @jasonwaltman3566
    @jasonwaltman3566 2 месяца назад +34

    Wife wife passed away 12 years ago from complications of her type 1.
    So many game changing advances have come about in the decade since she passed. It's bittersweet.

    • @LockerLovesYellow
      @LockerLovesYellow 2 месяца назад +1

      My late condolences man, some things don't get easier ❤️

    • @xeno2562
      @xeno2562 2 месяца назад +1

      I’m sorry man, hopefully nobody will have to die like that ever again.

    • @0kelvinzer0
      @0kelvinzer0 2 месяца назад

      Sorry for your loss. Was it uncontrolled? I did not know there could be complications wow

  • @maivaiva1412
    @maivaiva1412 2 месяца назад +210

    It's insane how a hundred years ago diabetes was basically a death sentence, and now we're this close to curing it for good. Science, babyyyy

    • @Baptized_in_Fire.
      @Baptized_in_Fire. 2 месяца назад

      No. It's a death sentence for people that eat exogenous glucose. That wasn't very available a hundred years ago, definitely moreso unavailable 200yrs ago

    • @Baptized_in_Fire.
      @Baptized_in_Fire. 2 месяца назад +1

      How did the genetics survive for so long of it were a death sentence?!? Lol

    • @JohnnyNumber11
      @JohnnyNumber11 2 месяца назад +26

      @@Baptized_in_Fire. How did Cancer survive, if it is a death sentence?

    • @Baptized_in_Fire.
      @Baptized_in_Fire. 2 месяца назад +3

      @@JohnnyNumber11 that is an illogical question that shows your lack of understanding of cancer.

    • @Baptized_in_Fire.
      @Baptized_in_Fire. 2 месяца назад

      @@JohnnyNumber11 the answer is that people still put toxic substances in their bodies, and there's way more toxins now than ever before in the world. Thank big ag, big "food", and big pharma, among others.

  • @Pj_garrett
    @Pj_garrett 4 дня назад

    This is truly amazing! I Pray that it's a step in the right direction for it's lasting cure.

  • @geologyjoerocks
    @geologyjoerocks 2 месяца назад +38

    I’m T1 and any progress towards a cure/treatment is great news!

    • @Veldrusara
      @Veldrusara 2 месяца назад +2

      I hope you can get help soon!!

  • @YakuzaMaster1
    @YakuzaMaster1 Месяц назад +40

    My brother died from diabetic-related complications in his mid-30s, so it's good to hear that we are moving much closer to remove another disability from harming more people.

  • @mrferris4379
    @mrferris4379 2 месяца назад +60

    We NEED to fund and support this research.

    • @itsgonnabeanaurfromme
      @itsgonnabeanaurfromme 2 месяца назад +2

      Go ahead then

    • @TexturaI
      @TexturaI 2 месяца назад +1

      Probably already is

    • @Reddeth6332
      @Reddeth6332 2 месяца назад

      Pharma will and then continue to force people into buying insulin.

    • @yveltheyveltal5166
      @yveltheyveltal5166 2 месяца назад

      the US will very likely try to halt this from even going much further, this was a discovery from China.

    • @StanlyCuppe
      @StanlyCuppe 2 месяца назад +1

      How do you think they made it this far? Shitloads of money.

  • @SamanthaEatsCookies
    @SamanthaEatsCookies 5 дней назад

    Everyone should thank this woman for allowing to be studied like this. What a huge step in science. She must be something excited and hopeful for her own future as well. Just amazing work.

  • @Toby0895
    @Toby0895 2 месяца назад +111

    Omg... Im START crying immediately...
    I was waiting for this and dreaming for this for the last 25 years... Thanks...

    • @antediluvianatheist5262
      @antediluvianatheist5262 2 месяца назад

      Are you in China?
      No?
      then you will never see it.
      big Pharma make too much money keeping you alive.

    • @EndoftheBeginning17
      @EndoftheBeginning17 2 месяца назад +5

      This is a very preliminary thing. If you're type 1 this is hope but a better thing would be to fix the immune system be adjusting the immune cells that remember this kind of stuff so it no longer creates an auto-immune condition first. If the auto immune conditions could be fixed that alone would be a God send, soooo many conditions are just auto-immune conditions.
      Fix that issue first and then fix the Diabetes and other conditions after

    • @Fractal_32
      @Fractal_32 2 месяца назад +1

      Let’s hope this is very viable, safe and cheap to reproduce.

    • @jasjfl
      @jasjfl 2 месяца назад +4

      This is a case study of one patient. We are still a long way from a cure. Kyle really shouldn't communicate in this way, it borders on misinformation.

    • @swagdaddy5387
      @swagdaddy5387 2 месяца назад +1

      Unfortunately, it probably won’t hit open market for anything under half a million dollars because insulin makes a lot of money

  • @SamuelKnaphus
    @SamuelKnaphus 2 месяца назад +34

    My mother has been type 1 since she was 11. Due to this any time any of us children were sick or wet the bed as young children she would check our blood sugar just to make sure it wasn’t pre-diabetes. Due to this she caught pre-diabetes in its earliest stage with my brother who was 8 at the time. She took him to the pediatrician, insisted it was pre-diabetes, and it was verified by some tests. The pediatrician wrote a prescription for some long acting insulin and that was that. Since my mother caught it so early and monitored it so vigilantly, over the course of the next 3 months his pancreas made a full recovery. He has never had complications with his pancreas since. This was in 2010 as well which makes it all the more impressive. He is 22 now :)

    • @RSClassicAngel
      @RSClassicAngel 2 месяца назад +2

      That's awesome!! Your mom is an amazing woman 😊

    • @SamuelKnaphus
      @SamuelKnaphus 2 месяца назад +1

      @@RSClassicAngel I agree!

  • @rogoth01themasterwizard11
    @rogoth01themasterwizard11 2 месяца назад +19

    millions of people around the world let out a yell of excitement, and a handful of people around the world let out a scream of absolute horror and despair.

  • @Silvercrypto-xk4zy
    @Silvercrypto-xk4zy Месяц назад

    That’s fantastic! Praying it continues to be successful

  • @RainbowDash1995
    @RainbowDash1995 2 месяца назад +175

    This is awesome!! My oldest son, not even 9 yet just got diagnosed with type one diabetes so to know that he may not have to live with this for the rest of his life is Huge!

    • @jankubicek9109
      @jankubicek9109 2 месяца назад

      Maybe I am wrong, i don't like to be breaker of a bad news but i got diagnosed like 25 years ago and I had to listen to all these bollock talks about possible cure from a start too. Believe it or not. It is pretty annoying and it won't help him long term I guarantee it. Its better to not hope and make it part of your life and deal with it like now its part of him. It can actually lead him to good "manners" in terms like food, sport activities, focus on
      his health, etc. You see diabetes is a huge business and curing it...would lower their annual profits.
      He is at least lucky he has much better options for controlling it.

    • @Baptized_in_Fire.
      @Baptized_in_Fire. 2 месяца назад +2

      Don't feed him carbohydrates. Feed him beef and he'll have a better go of it

    • @RainbowDash1995
      @RainbowDash1995 2 месяца назад +8

      @@Baptized_in_Fire. oh yeah, meats and cheese in general are like a godsend! Thankfully he likes that stuff, he's also level 3 autistic (you know, non verbal, flaps, makes unique noises) so it's a struggle finding a lot of food he will eat, but the boy loves his meats

    • @Baptized_in_Fire.
      @Baptized_in_Fire. 2 месяца назад +7

      @@RainbowDash1995 I also have autism. I don't agree with the different classifications (including levels), but that's neither here nor there, I suppose. They were created by midwits that weren't autistic, based upon neurotypical ideas of fitting in. My IQ falls in the genius range, a few standard deviations above the norm for the population at large. I can force myself to speak to fools that can't think in public, but it's painful. I can also force myself to mask so hard that no one knows I'm stimming. It's hell, be glad your son refuses to see the alleged benefits of that nonsense, to fit in with those not of clear minds. Properly guided, he can potentially do great things that others can't. Meat is a great fuel source for this. Ik our sensory issues differ between people, but I found that only eating beef greatly reduced mealtime stress, and made things easier and more enjoyable in novel ways. Plus I only get hungry about twice a day, which makes lots of other things easier too. Oh, and no more constipation, which is common in autism. I wish you both the best.
      Edit: careful with going overboard on cheese, it is a drug. Pick your poisons, but do so in moderation like others do with sugar. (Casomorphones, in cheese).

    • @Alexwhywest
      @Alexwhywest 2 месяца назад +4

      @@RainbowDash1995im also autistic and in school to become an autism specialist, and those classifications are outdated and based in ableism. Early research on autism comes from nazi Germany, if you dig into it enough. you can be, as you say, “level 1” and flap your hands, make noises. Strange way to describe it. Please look into ASD and avoid ABA, your child will thank you in the long run.

  • @Nicrom3
    @Nicrom3 2 месяца назад +21

    What great news. I was briefly confused with all the comments, but then I remembered that in the USA you were really ripped off with the insulin price.

    • @astraeanova4280
      @astraeanova4280 2 месяца назад +5

      My partner was offered a job in Nashville a few years ago but we stayed in the UK when we discovered they won't give Med insurance to type1 diabetics in that state.

  • @Marcus_Postma
    @Marcus_Postma 2 месяца назад +16

    I lost my best friend a couple of years ago. She had type one since 6 years old, and passed away at 29. I'm glad to see that progress is being made in this field.

    • @Malaphor2501
      @Malaphor2501 2 месяца назад +3

      I am so sorry. That is way too young and an absolute tragedy.

  • @Amidst_the_Grey
    @Amidst_the_Grey 2 дня назад

    I think of all of the type 1 students that I've had over the years and feel a lot of hope. This is research that I'll be following.

  • @miirico5398
    @miirico5398 2 месяца назад +469

    A week later: "Scientists who were researching cure for Diabetes all found dead from heart attacks!"

    • @lorewhore4195
      @lorewhore4195 2 месяца назад

      Kira if he worked for a USian pharmaceutical company kek

    • @John-qv5ux
      @John-qv5ux 2 месяца назад +47

      Not all of them. Some of them flew on Boeing 737 Maxes that suffered 'unfortunate accidents' in which they were the only victim

    • @eman67rp
      @eman67rp 2 месяца назад +9

      Or buy the rights and sit on it.

    • @sourdrop
      @sourdrop 2 месяца назад +16

      "They suddenly died from 'bullet-in-brain' disease."

    • @johndoe7270
      @johndoe7270 2 месяца назад +1

      You're damn right!

  • @Hull-m8
    @Hull-m8 2 месяца назад +35

    999 missed calls from Insulin manufacturers
    2 bullets dodged

  • @SonyaOutThere
    @SonyaOutThere Месяц назад +7

    My 31-month old daughter just got diagnosed with T1D and that these developments are underway really warms my heart. I’m sure, in her lifetime, a way will be found.

    • @Literally_a_Moth
      @Literally_a_Moth 11 дней назад

      If it’s not profitable then no. Only under special circumstances will this (might) be available.

    • @SonyaOutThere
      @SonyaOutThere 11 дней назад

      @ what do you mean “not profitable?”

  • @debbralehrman5957
    @debbralehrman5957 12 дней назад

    I hope it works. I have a young friend who was diagnosed in your teens. This would be great news for her and others.🙏🙏🙏💕

  • @TSPxEclipse
    @TSPxEclipse 2 месяца назад +1084

    So sad to hear that the research facility was mysteriously burned down, the woman dead by suicide from 3 separate gunshot wounds to the back of the head, and that the people who discovered the medicine were imprisoned for life following a routine traffic stop.

    • @Rosa_Neco
      @Rosa_Neco 2 месяца назад +12

      where did you HEAR that? i wanna read the source.

    • @Voidicpeculiarity
      @Voidicpeculiarity 2 месяца назад

      ​@@Rosa_Neco it's a joke about the government killing off people who do research that would stop major profits- insulin, in this case

    • @randoavis2
      @randoavis2 2 месяца назад +143

      @@Rosa_Neco its a joke

    • @liammorris1018
      @liammorris1018 2 месяца назад +105

      @@randoavis2 shows how f*cked the world is when people believe it lol.

    • @PaulFilmer
      @PaulFilmer 2 месяца назад +11

      ​@@liammorris1018 people believe someone is a crackpot and believes it happened when it didnt

  • @xarispapoutsakis8150
    @xarispapoutsakis8150 2 месяца назад +373

    Wouldnt count on it. The pharmaceutical industry isnt known for letting money slip right off their arms. I bet this whole breakthrough will be buried and forgotten in the future.....

    • @sirirond1990
      @sirirond1990 2 месяца назад +7

      On the USA

    • @worldz_of_visions
      @worldz_of_visions 2 месяца назад

      Exactly. Beat me to it. Was going to say: Rockefeller "medicine" will never allow it. If T1D is cured, their profits go away. This should be obvious.

    • @EchoAbenstern
      @EchoAbenstern 2 месяца назад

      I mean yea they get away with charging hundreds of dollars a month for a medicine that honestly is not that difficult to produce. Pretty much anyone who has either some skill with science or just sheer determination could make their own. The equipment isnt cheap (relative to the average person, dirt cheap to pharma) but yea it’s actually so fucked up

    • @Rose-yx6jq
      @Rose-yx6jq 2 месяца назад +4

      Not if we get this out there as much as we possibly can because we should not let this get buried.

    • @NoESanity
      @NoESanity 2 месяца назад +2

      @@sirirond1990 who do you think makes all the medicine for the rest of the world? 85% of medical advancement and drug creation happens in the US.

  • @ryanquick07
    @ryanquick07 2 месяца назад +20

    20 years ago when I was in seventh grade I did a project on stem cells being used to cure or treat diseases like this. Amazing to see it finally coming to fruition.

  • @leighkaiser7298
    @leighkaiser7298 4 дня назад

    A friend of mine did this a year or so ago (don’t remember the exact time). She is producing insulin. She has not needed insulin for over a year, and has an excellent A1C. It is so exciting!!

  • @liamwaselko4128
    @liamwaselko4128 2 месяца назад +406

    Wait until the researchers mysteriously “disappear”.

    • @CokSoku
      @CokSoku 29 дней назад +12

      Do you know how most medical research works? Once the discovery is made, the info is basically out there immediately. No quelling progress.

    • @democracy_enjoyer
      @democracy_enjoyer 29 дней назад +3

      those cia jokes are old and borong asf, can they end for once?!

    • @CokSoku
      @CokSoku 29 дней назад +8

      @@democracy_enjoyer The implication is the pharmaceutical industry, not government. Corporations run this country, after al

    • @Artok444
      @Artok444 28 дней назад +3

      You kinda paranoid?

    • @CedricBassman
      @CedricBassman 22 дня назад

      @@CokSoku
      Yeah and as you already said the Information is out there, so it's still a dumb "joke"

  • @bactrosaurus
    @bactrosaurus 2 месяца назад +115

    If the price for Insulin wasn't artificially inflated and third world countries would be allowed to produce their own, it wouldn't be much of a problem. But still impressive

    • @kahlzun
      @kahlzun 2 месяца назад +12

      It's only artificially inflated in some places. It's like $7 for a vial in aus.

    • @bactrosaurus
      @bactrosaurus 2 месяца назад +5

      @@kahlzun yeah mainly US.

    • @TheEveryoneGames
      @TheEveryoneGames 2 месяца назад +9

      Insulin is free in most of the world. Thats a US exclusive problem

    • @GeneralKenobiSIYE
      @GeneralKenobiSIYE 2 месяца назад

      What should it cost? I would get a bottle of the stuff for $20 (not covered by insurance as it was for a pet) when I was giving my cat insulin for the last two years of his life.

    • @cpK054L
      @cpK054L 2 месяца назад

      ​@@TheEveryoneGamesis free because the US subsidized it

  • @megan00b8
    @megan00b8 2 месяца назад +261

    I've seen this one before, here's the issue: this doesn't cure the root cause and it only works for her because she's already on strong immunosuppressants. If these cells could survive without compromising your immune system for at least a year I'd call it a huge win, but the truth is that getting brand new insulin producing cells into a person was never the issue, it is keeping them alive. When I was diagnosed I was told it's okay, they're on the brink of the solution to this issue, just three more years and we'll have a cure! Well that was eleven years ago and we are still "just three years away" from a cure so yeah, hate to be the bearer of bad news, but it is what it is.

    • @TeddyLucia1006
      @TeddyLucia1006 2 месяца назад +12

      There are ways to manipulate cells to allow them to evade the immune system. Some cancer cells do it, for example. Seems like there's at least some effort in that direction, so maybe it'll really happen in your lifetime. 🤞

    • @jotave49
      @jotave49 2 месяца назад +8

      Exactly my thoughts on the matter.
      There won't be a cure for type 1 diabetes until we can cure most auto inmune diseases

    • @miguelg1716
      @miguelg1716 2 месяца назад +5

      Same but for me was in 94. Doctor said 2-3 years and insulin pumps will be readily available as a transition to a full cure in the next decade... That did age well...

    • @Kelly_Ben
      @Kelly_Ben 2 месяца назад +1

      ​@@miguelg1716my mother desperately needs an insulin pump. Her diabetes is incredibly hard to control, as it's a mix of type 1 and type 2. But she's retired, and can't afford the $6k. 'Merica

    • @nerofarreach2417
      @nerofarreach2417 2 месяца назад +3

      Well, the difference is that these are her own cells, they should just be ignored by the immune system because of that

  • @blakenipper10
    @blakenipper10 Месяц назад

    Type 1 here, diagnosed at 17 in 2019. I can only hope this research doesn't magically "disappear"

  • @nightxiv9329
    @nightxiv9329 2 месяца назад +13

    I can only imagine how expensive it’ll magically be to retrieve a cell sample and modify it.

    • @jennifergarrett1449
      @jennifergarrett1449 2 месяца назад +6

      stem cell therapy is never cheap, but big pharma largely has no control over it. The patient in question is on anti rejection drugs after a liver transplant, which is why she didnt reject the cells

  • @waldonobody
    @waldonobody 2 месяца назад +17

    As someone with T1D, this excellent news

    • @hanzzel6086
      @hanzzel6086 2 месяца назад

      Still going to be at least 7 years before it makes it to hospitals in the U.S/West. But still amazing news.

    • @TeemoQuinton
      @TeemoQuinton 2 месяца назад

      ​@@hanzzel6086nah. It'd be fast tracked through FDA like Covid stuff was. FDA Fast track is literally built for this.

  • @Darkest_matter
    @Darkest_matter 2 месяца назад +216

    we'd have had flying cars by now if researchers didn't have so many unfortunate "accidents"

    • @agustinfranco0
      @agustinfranco0 2 месяца назад +9

      nah, the reason we dont have flying cars is to PREVENT accidents.

    • @rabbaniazzahra1784
      @rabbaniazzahra1784 2 месяца назад +1

      @@agustinfranco0 just have AI to drive the cars

    • @agustinfranco0
      @agustinfranco0 2 месяца назад +8

      @@rabbaniazzahra1784 we are not even there for normal cars,

    • @FogsterBell
      @FogsterBell 2 месяца назад +15

      We already have flying cars. They are called planes and helicopters.

    • @rakkatytam
      @rakkatytam 2 месяца назад +5

      Flying cars are a very bad idea, cars in general are archaic and backwards

  • @ZombieSazza
    @ZombieSazza Месяц назад +4

    Shout out to John James Rickard Macleod for co discovering insulin, couldn’t have done it without him
    During his life he really didn’t get the credit he deserved and was only acknowledged properly after his death (typical), so I’m always happy to find any chance to mention John James Rickard Macleod and his co discovering of insulin
    He’s buried 5 minutes from my house and my city recently opened a memorial garden in his honour (Aberdeen, Scotland)

    • @RNMom424
      @RNMom424 День назад

      Thanks for the information! I like knowing things like this! And yes, I think he deserves a Memorial Garden, at the very least!! I hope someone keeps it up! Would you please, if the ubiquitous "they" don't? Thank you again! Have a Verý Merry Christmas, & a Blessed New Year!!!
      Thank you Mr. McCloud for all your work & the finished product! RIP!

  • @dovebair
    @dovebair 2 месяца назад +17

    OMG I said the exact same WHAAAAT when you said the title. We basically jinxed! You're pretty damn clever in knowing your audience ❤️

  • @BunkerSquirrel
    @BunkerSquirrel 2 месяца назад +25

    Insulin companies: and I took that personally

    • @angelmatiastorres
      @angelmatiastorres 2 месяца назад +1

      I mean it's just for one type of Diabetes not all of them

    • @thatpandaz6094
      @thatpandaz6094 2 месяца назад

      @@angelmatiastorres That's still a HUGE loss.
      Any loss to profit for that matter is a huge loss and they will fight against it.

    • @aaronburdon221
      @aaronburdon221 2 месяца назад

      @@thatpandaz6094 Yea, that's like 30% of their profit margin.

  • @ophanim9170
    @ophanim9170 2 месяца назад +67

    The biggest challenge from diabetes for me has been mentally. It made me extremely depressed to the point I didn’t care if I lived or died. I just wanted to feel normal again. Type 1 runs in my family. I’m not as depressed as I use to be but I still haven’t found that normal feeling. I hope there is a cure

    • @kshitijbachhav5332
      @kshitijbachhav5332 2 месяца назад +5

      There will be a cure. Stay strong brother.

    • @bruhyou4305
      @bruhyou4305 2 месяца назад +6

      same dude, I just want to fking relax without needing to think about this. there's so many things that I can't do I feel like there's a leash around my neck all the time

    • @screechandmoan
      @screechandmoan 2 месяца назад +1

      I feel the exact same way, my friend. This is a big step in the right direction for us though, and we've persisted this long! Might aswell stick around for the cure. 😉

    • @karhonglooi7485
      @karhonglooi7485 2 месяца назад

      Well well well, sad life you have there, but the pharmaceutics industry ain't letting this cure slide so they can reap their sweet insulin profits. A sad world it is

    • @WolfJinx7
      @WolfJinx7 2 месяца назад

      ​@@karhonglooi7485real jerk move you saw people admitting they're hurting and just had to spit on the little flame of hope they have nice move

  • @baptixm
    @baptixm 7 дней назад

    My boy was diagnosed at the age 5 with Type I. It’s been 6 years, this treatment can’t come soon enough, I’ll pray.

  • @Im-Not-a-Dog
    @Im-Not-a-Dog 2 месяца назад +5

    As a Type 1, this is huge and I cant wait to hear what comes of this.

  • @almightyk11
    @almightyk11 Месяц назад +5

    While people are here talking about how the companies will react, I would like to inform people in the USA that Walmart sells Insulin for $25

  • @alexdawson5293
    @alexdawson5293 2 месяца назад +13

    I'm amused it was fixed with the equivalent of turning them off and turning them back on again

    • @DangerSquiggles
      @DangerSquiggles 2 месяца назад +2

      And a lifelong regimen of immunosuppressive medication

  • @Tyredest
    @Tyredest 19 дней назад +2

    This is why I LOVE studying genetics! You might just change the word

  • @Chillout_dude
    @Chillout_dude 2 месяца назад +14

    Remember none of these researchers have suicidal thoughts

  • @CONSTANTINE-8888
    @CONSTANTINE-8888 2 месяца назад +53

    Corporations Wouldn't like this. A cured patient is a lost customer

    • @williameldridge9382
      @williameldridge9382 Месяц назад

      This common rhetoric is old and tired, there is zero proof corporations want people to remain sick and in fact, withholding cures actually hurts their bottom line. There are essentially an infinite number of diseases humans can succumb two and there will always be new ones that nature creates every single day. Withholding cures would be universally stupid on the part of corporations.

  • @Abcdefghijklmnopqrstuvwxyz1024
    @Abcdefghijklmnopqrstuvwxyz1024 2 месяца назад +8

    Proof stem cell research is one of the most important types of research

    • @deauthorsadeptus6920
      @deauthorsadeptus6920 2 месяца назад +2

      Not really. Its promising, but with its own drawbacks and issues, that remain unsolved (so far). Think of it as fusion reactors, insane potential, but you wouldn't see results even in decade, or two, or three...

  • @melissapelletier2138
    @melissapelletier2138 День назад

    It's amazing all the advancements. The medical field has made in such a short amount of time. . It gives me so much hope for the future generations.

  • @sknnyd2676
    @sknnyd2676 2 месяца назад +5

    As the father of an 11 year old who was diagnosed at 8 this is wild

  • @BatMite19
    @BatMite19 2 месяца назад +5

    I've been type 1 for 57 years. Throughout my life there have been these BIG BREAKTHROUGH moments, with "a cure in sight!" But then disappear. There is a lot of furor to get research money. but so far, the external insulin pump is the only thing that has come through for us.

    • @lillipi3594
      @lillipi3594 2 месяца назад +1

      Type1 for 35 years here. I really understand your way of seeing it. None of the BREAKTHROUGHS have been worth the hype so far 😉

    • @JM-dc5rn
      @JM-dc5rn 2 месяца назад

      I have had a chronic autoimmune illness for 12 years and the amount of times a doctor has told me that they are close to at least a medicine to suppress it for normal life and then i never hear about the medicine ever again has just made me give up. I never believe them anymore.

    • @BatMite19
      @BatMite19 2 месяца назад +1

      @@JM-dc5rn Don't give up! Someday one of these cures will work. But a fair amount of skepticism and patience is necessary.

  • @SolLunaris
    @SolLunaris 2 месяца назад +24

    Itll cost at least 100000 to do the treatment. The pharmaceutical companies are not going to let this happen unless they can still get their bottom dollar. Diabetes is a life long check for them and has been for a while now.

    • @MTGHedgefund
      @MTGHedgefund 2 месяца назад +1

      Why would they not charge a fortune for it? This will cost them billions to develop and maintain and it is a very complex procedure

    • @hoytabaker6414
      @hoytabaker6414 15 дней назад

      The infusions I receive for an autoimmune disorder costs over $130,000/yr and it is not a cure. I enrolled in a gene therapy clinical trial. I may never see the results of it, but my son may.

  • @angsern8455
    @angsern8455 4 дня назад

    That's great! We need to make sure these researchers are safe

  • @JustAnotherYTer
    @JustAnotherYTer 2 месяца назад +5

    Type 1 diabetic here, very enthused to see some progress here since even my pump hasn’t had many major changes in 8 years.

    • @elizabethprosher
      @elizabethprosher 2 месяца назад

      They discontinued my previous pump that I’ve had for 7 years. It was like saying goodbye to an old friend.

  • @canoiv
    @canoiv 2 месяца назад +7

    don't forget kids, if it's not profitable, it won't happen

    • @baronbrummbar8691
      @baronbrummbar8691 2 месяца назад

      you can make money out of almost everything
      ........
      this whole argument "a cure of cancer will never be released as it is more profitable to heal" is bs
      .......
      if a company discovers it
      they can demand insane premiums as they will control 100% of the market with it and make butloads of money

  • @jesusangulosolano8375
    @jesusangulosolano8375 2 месяца назад +25

    The problem with this treatment is that it may not suit some to most type 1 diabetes patients as there is an autoimmune destruction of these cells in the first place (probably why a 5 year follow up is required), maybe with immunodepressants it could work, but then there is the problem of immunosuppresion itself

    • @skolkor
      @skolkor 2 месяца назад +4

      That's a really good point.

    • @stephenmadl5609
      @stephenmadl5609 2 месяца назад +5

      Not to mention the tendency of these types of treatments to turn cancerous.

    • @bobgarrish
      @bobgarrish 2 месяца назад +4

      I was also curious about that angle. I have damage to my islet cells from chemotherapy, so the same symptoms, but I'm not type 1 and my body wouldn't attack the cells.
      Unfortunately, because few people like me exist, most research on transplants and cloning these cells involves/assumes use of immunosuppressants, which are a big NO for me.
      Transplanted islet cells have been in use in procedures in Canada for over 20 years, so the cloning must be the first. Given the 20 years I just mentioned, I wouldn't get your hopes up for mass market - last I checked, you still had to get into a research study to get the procedure as a Canadian.

    • @travishunter8573
      @travishunter8573 2 месяца назад

      ​@@stephenmadl5609these treatments do not turn cancerous, they do not have their normal cell growth regulators turned off like cancer

    • @finch4328
      @finch4328 2 месяца назад +6

      The woman this was done on was already on immunosuppressants so yes, good chance they’d be needed if this method is replicated on other patients and as you mentioned, those cone with their own host of problems.

  • @samusrules93
    @samusrules93 28 дней назад +2

    T1 here. Been a lot of 'cures' over the years. Don't get me wrong, I appreciate any attention brought to the disease, and I think you had a good take on this news in general. But I remain skeptical, because any time a 'cure' involves just getting the body to produce insulin again (which has been achieved in several ways now), the autoimmune response invariably kills off all those cells again.
    What would be interesting is if one of these treatments could last even a month, let alone 5 years. A shot every month beats an insulin pump, or 5+ shots per day, and needing to constantly get insulin. So I'll keep on hoping and believing in progress!

  • @werelemur1138
    @werelemur1138 2 месяца назад +5

    My sister's endocrinologist predicted this about 35 years ago.

    • @Superjake789
      @Superjake789 Месяц назад +1

      I was the one who predicted your sister’s endocrinologist would say that 70 years ago

    • @sladey21
      @sladey21 Месяц назад

      I predicted flatscreen tvs 20 years ago

  • @shanematthews1985
    @shanematthews1985 2 месяца назад +18

    I felt a great disturbance in the Market, as if millions of Insulin Manufacturers suddenly cried out in terror and were suddenly silenced. I fear something great has happened.

    • @SeqK
      @SeqK 2 месяца назад +1

      I too can feel the force and it's strong with this one

    • @gregbuster4187
      @gregbuster4187 2 месяца назад +3

      The Pharmaceutical Empire will strike back.

    • @deauthorsadeptus6920
      @deauthorsadeptus6920 2 месяца назад

      Only in US. Cause insulin isn't actually very expensive even in canada. And same companies are actually doing (and are interested) with similar researches, you innovate or die with the industry. And if you were the one to kill it by making every other treatment obsolete...

  • @EshanAbbas
    @EshanAbbas 2 месяца назад +18

    That’s a big, VERY BIG IF. There’s so many factors that could come into play later on. And yes, big pharma.

  • @breadfanornofan1148
    @breadfanornofan1148 18 дней назад

    My mom is almost 70 now and has been a Type 1 Diabetic for 66 of those years. I'm 100% showing her this and I'm going to see if her doctor can find out information on this. 66 years of diabetic shock, hospital scares and kidney failure that comes with the dietary restrictions among other things.

  • @Aniware
    @Aniware 2 месяца назад +155

    this shi gonna be practically impossible to afford💀💀💀

    • @randomtrashhandle
      @randomtrashhandle 2 месяца назад +48

      Not if you live outside the US lol

    • @rickdelpino472
      @rickdelpino472 2 месяца назад +20

      At the beginning would be...but it will be cheap in the future.

    • @Cwg.
      @Cwg. 2 месяца назад

      @@rickdelpino472 If its expensive its only going to be because someone wanted to make alot of money. Either by being bought out for millions by someone to then jack it up. Or just a change of heart by the makers to do good

    • @travishunter8573
      @travishunter8573 2 месяца назад +6

      The only thing is for insurance this may be cheaper than paying for all of the medical supplies for the rest of your life.

    • @GogiRegion
      @GogiRegion 2 месяца назад +14

      To be fair, people said that about basically every major medical advancement, even ones that seem simple and affordable now like penicillin or x-ray machines.

  • @Jake-rv8td
    @Jake-rv8td 2 месяца назад +5

    Too bad I live in the United States. That procedure is going to cost $575,000 and our health insurance won't cover it.

  • @knifelover73
    @knifelover73 2 месяца назад +55

    Gonna be terrible when all these researching simultaneously have unrelated fatal car accidents after the pharmacy companies find out about this.

    • @spindash64
      @spindash64 2 месяца назад

      Nah, the short term profit payoff is just too good for them to pass up

  • @carpediemarts705
    @carpediemarts705 25 дней назад +2

    A decade ago someone was badly burned and his medschool friend used a sprayer to spray skin cells onto the badly burned face and neck. The man healed perfectly with an absence of melanyn ; no scars. We still don't have FDA approval of something that was so effective. Why?

    • @asktheetruscans9857
      @asktheetruscans9857 24 дня назад

      Because someone with money has to spend all the money it takes to get it approved (in the hopes of making more money than they spent).

    • @carpediemarts705
      @carpediemarts705 24 дня назад

      @asktheetruscans9857 yeah thanks for the pessimist bs answer.

    • @simonnachreiner8380
      @simonnachreiner8380 15 дней назад

      Because a sample size of one isn't a study and taken out to a patient pool of thousands who knows what complications might arise.