Thanks very much. At 57 min on the question of whether it is always a good idea to suppress muscle protein breakdown in pre-op patients, I recall a talk by J. Mitchell (about 2 years ago) in which he mentions that in animal models ( and some evidence in humans too, I think) that some level of fasting for 24 to 48 hours before surgery greatly improved outcomes. Some evidence along these lines has been collected for cancer patients fairing better when being fasted a little before radiation or chemo (Ref. work of V. Longo). No mention of age stratification though. Overall, exercise does appear to improve outcomes in cancer patients.
Thanks very much. At 57 min on the question of whether it is always a good idea to suppress muscle protein breakdown in pre-op patients, I recall a talk by J. Mitchell (about 2 years ago) in which he mentions that in animal models ( and some evidence in humans too, I think) that some level of fasting for 24 to 48 hours before surgery greatly improved outcomes. Some evidence along these lines has been collected for cancer patients fairing better when being fasted a little before radiation or chemo (Ref. work of V. Longo). No mention of age stratification though. Overall, exercise does appear to improve outcomes in cancer patients.