Microfluidics Adventures #3: Microfluidic chips

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  • Опубликовано: 31 июл 2024
  • The Lutetium Project is back with part three of our Microfluidics Adventures! We're gonna show you microfluidic chips as you've never seen them before. Let’s mix some microdroplets!
    ↓ More infos and links in the description ↓
    ---------------------------------------­----------------------------
    LINKS:
    French version: • Aventures microfluidiq...
    Subscribe to the channel : / thelutetiumproject
    Follow us on Twitter : / theluproject
    Visit our website: www.lutetium.paris/en

    ---------------------------------------­----------------------------
    RELATED BOOK:
    Patrick Tabeling, Introduction to microfluidics, Oxford University Press (2005) books.google.fr/books/about/I...

    ---------------------------------------­----------------------------
    RELATED ARTICLES :
    Lucas Frenz, Abdeslam El Harrak, Matthias Pauly, Sylvie Bégin-Colin, Andrew Griffiths, Jean-Christophe Baret
    Droplet-Based Microreactors for the Synthesis of Magnetic Iron Oxide Nanoparticles
    Angewandte Chemie International Edition 47: 6817-6820 (2008)
    onlinelibrary.wiley.com/doi/10...
    Jeremy Agresti, Eugene Antipov, Adam Abate, Keunho Ahn, Amy Rowat, Jean-Christophe Baret, Manuel Marquez, Alexander Klibanov, Andrew Griffiths and David Weitz
    Ultrahigh-throughput screening in drop-based microfluidics for directed evolution
    PNAS (2010), doi: 10.1073/pnas.0910781107
    www.pnas.org/content/107/9/400...
    All of the research footage used in this video can be found on the RUclips channel of the Biochemistry Lab at ESPCI : / @lbcespci4094
    ---------------------------------------­----------------------------
    ACKNOWLEDGEMENTS:
    Philippe Nghe, Biochemistry Lab www.lbc.espci.fr/
    Paul Boniface, Espace des sciences Pierre-Gilles de Gennes www.espgg.org/
    Fabrice Monti, Microfactory SAS, www.microfactory.eu/
    MécaWet team, PMMH lab, www.pmmh.espci.fr/~jbico/
    EC2M team, Gulliver lab, www.ec2m.espci.fr/
    Perrine Franquet, Institut Pierre-Gilles de Gennes pour la microfluidique www.institut-pgg.fr/
    ---------------------------------------­----------------------------
    STRUCTURE OF THE VIDEO:
    00:00 Using the chip
    01:30 Output: microdroplets!
    02:28 Why make microdroplets?
    03:24 Laminar and turbulent flows
    05:03 Mixing at the microscale
    05:36 Conclusion
    ---------------------------------------­----------------------------
    CREDITS:
    Host:
    Marie Boulez
    Directing, animation:
    Hoon Kwon
    Scenario:
    Guillaume Durey, Mathias Kasiulis, Arnaud Reitz
    Editing:
    Léa Bello, Hoon Kwon
    Studio, visual identity:
    Juliette Nier
    Theme music, background music:
    Pierre David
    Production:
    Guillaume Durey, Mathias Kasiulis

    ---------------------------------------­----------------------------
    The Lutetium Project is a PSL students’ initiative conducted as part of IDEX ANR-10-IDEX-0001-02 PSL and funded by:
    PSL Research University - www.univ-psl.fr
    ESPCI Paris - www.espci.fr
    Espace des sciences Pierre-Gilles de Gennes - www.espgg.org
    ESPCI Alumni - espci.alumni.paris
    le Fonds ESPCI Paris - www.espci.fr/fr/nous-soutenir...

Комментарии • 104

  • @FakhrurrazieJaffar
    @FakhrurrazieJaffar 5 лет назад +62

    I love how you explain the phenomenon with adequate visual aid.

  • @ameyakale2739
    @ameyakale2739 4 года назад +2

    This series was incredibly explained. Simple and elegant. Loved it.

  • @krrimy
    @krrimy 3 года назад +1

    My husband who has been in the field for over 20 years can not explain with this level of patience. 😂!! I’m so glad I found you!

  • @sebastianbarbera5060
    @sebastianbarbera5060 4 года назад +3

    More Videos! More Videos! More Videos! You guys have produced the most visually stunning science content I've seen yet on RUclips!

  • @AG-pm3tc
    @AG-pm3tc 5 лет назад +13

    top notch content guy's, don't know how i missed such youtube gold

  • @imranq9241
    @imranq9241 4 года назад

    I have always been fascinated with fluidics and this explanation was so clear and helpful. Thank you!!

  • @h.dsheela1357
    @h.dsheela1357 4 года назад

    I am literally overwhelmed by the content and explanation.Please keep up this good work!!Sending love from India!!

  • @benamadi3107
    @benamadi3107 4 года назад

    Thank you for explaining the concept so simply!

  • @the_lost_spaniard
    @the_lost_spaniard 6 лет назад +11

    Great video guys!

  • @BillEngwall
    @BillEngwall 4 года назад

    The only channel that has in depth intro to microfluidics

  • @WangleLine
    @WangleLine 5 лет назад +7

    This is soooo well made - I'm in love with this series :D

  • @francestorreysirdevan4774
    @francestorreysirdevan4774 3 года назад

    Really, really, REALLY great job. Really impressed by your work. Really helpful! Thank you guys!!!

  • @somnathsingh1023
    @somnathsingh1023 4 года назад

    Thank you so much for making us understand a complex topic like this in a very easy way :D

  • @alanoodalharthi9855
    @alanoodalharthi9855 3 года назад

    I loved this series, it has helped me so much! I found the visuals were really useful, the explanations were clear and concise, lastly, this is a topic the presentation style was easy to follow and caught my attention! Well done! and thank you ;)

  • @TranscenDaMental
    @TranscenDaMental 2 года назад

    Amazing!!!! I’ve been formulating some unbelievable ideas from researching technology such as this. Thank You all for doing so well in your fields of science!

  • @thejoojoo9999
    @thejoojoo9999 Год назад

    Great video ! Very clear and concise, and beautiful visuals and animations.

  • @maciasbeatriz
    @maciasbeatriz 5 лет назад +1

    That was fantastic. You so clear!

  • @saeidmollaei2163
    @saeidmollaei2163 6 лет назад

    Interesting and informative as always. Thank you so much.

  • @DamonGarfield
    @DamonGarfield 5 лет назад +1

    Very cool visuals! Keep the good content coming.

  • @tanzeelurrahman5648
    @tanzeelurrahman5648 5 лет назад +1

    Indeed an amazing video, lot of visual science.

  • @sanampudasaini3379
    @sanampudasaini3379 5 лет назад +2

    Excellent video. Very informative.

  • @vans4lyf2013
    @vans4lyf2013 5 лет назад +14

    Thanks for this incredible series. Are there any books that you would recommend in order to learn this all from absolute basics and beginners level?

  • @kerryai
    @kerryai 4 года назад

    This is very informative video. Keep uploading more.

  • @evgeniisharaborin8071
    @evgeniisharaborin8071 3 года назад

    You have awesome explanation, Thank you!

  • @pierre-alexandrelaurent3999
    @pierre-alexandrelaurent3999 5 лет назад

    Very good work !

  • @alimobedi1399
    @alimobedi1399 3 года назад

    that was so educational! nice explanation! thank you!

  • @hqs9585
    @hqs9585 2 года назад

    Thanks for this introduction

  • @iftekharuddin
    @iftekharuddin 5 лет назад +1

    Thanks for the great video.

  • @nitishupadhyay3972
    @nitishupadhyay3972 3 года назад

    Outstanding

  • @teneoaristocrata3270
    @teneoaristocrata3270 3 года назад

    Very impressive. Thank you very much.

  • @Mostafa-cv8jc
    @Mostafa-cv8jc 3 года назад

    very welll made and underrated video

  • @sayragorgani3639
    @sayragorgani3639 5 лет назад

    Awesome video!

  • @naziasultana5665
    @naziasultana5665 2 года назад +1

    Amazing explanation!❤❤

  • @sivaneshm8306
    @sivaneshm8306 5 лет назад +1

    Was awesome.. 😍😍 i luv dis subject

  • @rock3tcatU233
    @rock3tcatU233 4 года назад +1

    Wow, you basically took a 300 page book on microfluidic basics and made it understandable.

  • @edwardyue5884
    @edwardyue5884 5 лет назад

    Great video! Nice Job

  • @saram263
    @saram263 2 года назад

    Awesome demo and presentation

  • @brandonlewis2599
    @brandonlewis2599 5 лет назад

    very cool, thanks for this!

  • @J9Burgess
    @J9Burgess 2 года назад

    very well explained, thank you!

  • @ayomikunsamuelesan245
    @ayomikunsamuelesan245 5 лет назад

    Very enlightening video

  • @rubaethhossain4893
    @rubaethhossain4893 3 месяца назад

    Very nice, I think microfluidics is the future. Imagine a bio-chip that reads off your current health status, that would be very cool.

  • @sueanoimm
    @sueanoimm 6 лет назад

    I love your video!

  • @markkraman886
    @markkraman886 5 лет назад +1

    awesome video

  • @krysellebarretto1668
    @krysellebarretto1668 3 года назад

    nice video, may i know from where or which article did you get the info of three water inlets

  • @malabarescallejeros4920
    @malabarescallejeros4920 5 лет назад +1

    How do you filter the liquid before injecting them to the microfluidic system?

  • @beingentrepreneur9458
    @beingentrepreneur9458 5 лет назад +1

    Can you please elaborate on the topic of chemical reactions at microscale ?

  • @AbdurRahman-nq5nb
    @AbdurRahman-nq5nb 5 лет назад

    V informative and outstanding video....

  • @yanaungmoe6294
    @yanaungmoe6294 5 лет назад

    May I know the camera you use?

  • @MsSixtine16
    @MsSixtine16 3 года назад

    Amazing thank you

  • @theNeuo13
    @theNeuo13 4 года назад

    Thank you for the video. It was very informative. But could you please talk about the use of IDT in microfluidics.

  • @pradeepselvan
    @pradeepselvan 4 года назад

    wow nicely explained

  • @mohsina9958
    @mohsina9958 6 лет назад

    thanks!

  • @iron4us
    @iron4us 2 года назад

    I NEED ONE OF THOSE!!!

  • @alazsworld
    @alazsworld 6 лет назад

    nice video and content

  • @pjeehoon
    @pjeehoon 3 года назад

    Great contents. I actually want to implement your explanation. What would be the typical volume of a droplet? Can it move slowly enough to take a picture? If not slow enough, how can i make a smaller and slower droplet by adjusting what factors?

  • @DDDelgado
    @DDDelgado 5 лет назад +1

    2:53 wow that's great for my research

  • @mexuscentral
    @mexuscentral 2 года назад

    How they make graphene transparent to mix with the fluids?

  • @ProjectPhysX
    @ProjectPhysX 5 лет назад

    2:43 this is so cool!

  • @PrinceFlumph
    @PrinceFlumph 3 года назад

    Wait. That small vial is full of individual drops?

  • @tolibelom
    @tolibelom 2 года назад

    beautiful

  • @zgjimmustafa6572
    @zgjimmustafa6572 2 года назад

    Can you recommend a Programm for the Design of This chip?

  • @tanjiro3285
    @tanjiro3285 3 года назад

    I was submerged into the content ❤️

  • @MrDieselakias
    @MrDieselakias 2 года назад

    if we increase the flow rate in a microfluidic channel, wont we get a turbulent flow at some point?

  • @darshikaverma9170
    @darshikaverma9170 4 года назад

    awesome

  • @zohaibakramlali6261
    @zohaibakramlali6261 3 года назад

    Sir any suggestions r any review paper for materials selection of for spherical droplets microfluidics robot it will be great kindness for me

  • @nano7586
    @nano7586 Год назад

    Microfluidics is so interesting. But I'm worried about the accuracies and precisions when mixing liquids. What's the progress here?

  • @icebluscorpion
    @icebluscorpion 5 лет назад

    You will get turbulent flow in high viscose or very small areas if you cross tangentially in opposite directions of the streams doto of inner friction of the both fluids like rubbing two surfaces against another

    • @icebluscorpion
      @icebluscorpion 5 лет назад

      You can also get turbulent flow/mixing with oscillating fluids... That's basic knowledge I suppose, but it doesn't get mentioned a single time in this video

    • @fillentropy6519
      @fillentropy6519 5 лет назад

      context... your supreme intelligence is not needed in this video.

  • @rigoluna1491
    @rigoluna1491 4 года назад

    This was a great channel, a shame there hasnt been a video in 2 years. Hopefully you guys post again

    • @TheLutetiumProject
      @TheLutetiumProject  4 года назад +2

      Thanks! Please stick around, in a couple months we'll release tons of new stuff!

    • @jtt6874
      @jtt6874 4 года назад

      The Lutetium Project I’ll be waiting for it

  • @vectoronic
    @vectoronic 5 лет назад +3

    find this very interesting.
    untaped potential

  • @robloxinaalisa8440
    @robloxinaalisa8440 5 лет назад

    More videos please

  • @sivaneshm8306
    @sivaneshm8306 5 лет назад

    Loved it dear

  • @raezad
    @raezad 3 года назад

    3:19 ah yes, the Jim Crow Laws Chip

  • @johnbrooks527
    @johnbrooks527 5 лет назад

    More plz

  • @chang.stanley
    @chang.stanley 5 лет назад

    I thought if you added soap the mixture would emulsify? :o

    • @timjackson3954
      @timjackson3954 5 лет назад +1

      It did. An emulsion consist of tiny droplets of one component dispersed in the other. They were just rather large drops compared to the sort of emulsion we are used to dealing with. Just stick it in a blender to make them smaller.

  • @JC-kb8vb
    @JC-kb8vb 6 лет назад

    What is the Litetium Project?

  • @benj1008
    @benj1008 4 года назад

    Great video! Very interesting presentation too.
    A small suggestion: try to tone down the gesturing with your hands when speaking -- it's distracting and looks like you are conducting an orchestra. ;)

  • @JP-br4rk
    @JP-br4rk 5 лет назад

    One thing, laminar versus turbulent flow is also dependent on the velocities of the liquid in question. I observed this with a 1/36” ID tubing where I varied the flow rate of two different inlets of colored water. In high velocities, the flow was laminar and there were two distinguishable colors. However, when I decreased the flow rate to a tenth of its original value, the flow was turbulent and there were no distinguishable colors visible, only purple. If you want a bit more of a background, I believe some of the properties distinguishing laminar versus turbulent flow are described by the Reynolds number and the Damkohler number

    • @harryshaw5360
      @harryshaw5360 5 лет назад +1

      John Putziger inertia is proportional to velocity though

    • @tkrase87
      @tkrase87 5 лет назад

      That doesn't make sense.. turbulent flow is characterized by high Reynolds number which is proportional to velocity. Maybe your experiment had less control than you thought.. if the flows had different velocities, mixing is likely to occur.

    • @yehiaismail2451
      @yehiaismail2451 5 лет назад

      Are You All concentrating on the Small or big droplets
      You know, the jigilly ones maybe that is why most of the viewers age guys; sex sells. Does anyone doughts that the host of This show is making slightly out of the ordinary hand motion To jiggle and wiggle the mellonious droplets. Maybe we need a body langage expert to confirm that

    • @mayurmahale3049
      @mayurmahale3049 5 лет назад +1

      I believe that's diffusion.

  • @AbdurRahman-nq5nb
    @AbdurRahman-nq5nb 5 лет назад

    Will need ur help in this technology...

  • @sebastianstewart6894
    @sebastianstewart6894 4 года назад

    Basically vacoule science.

  • @jasongooden917
    @jasongooden917 4 года назад

    With this technology they could make an artificial kidney

  • @drakedorosh9332
    @drakedorosh9332 3 года назад

    2:27 minutes should have been in the first video introduction. You get into all this detail about making your chip before anyone knows why we would bother. You mention in the earlier episodes that microfluidics is used in inkjet printers too bad you didn't have any footage but you did have footage of these microscopic petri dishes. That would generate real interest and galvanize attention. Personally I came to find out about valves and logic gates but that isn't here had you started with the microlab in the intro we would know where you were going. Here it is what I was looking for: ruclips.net/video/m5WodTppevo/видео.html but now I will watch your videos too.

  • @alokjaiswal3478
    @alokjaiswal3478 5 лет назад

    Very informative and concept clearing.
    SUGGESTION :- the length of video is small and lacks explanations at some points.
    Accent is slight problematic for foreign viewers.

  • @Decco6306
    @Decco6306 4 года назад

    This technology is just going to make my inkjet printer cartages more expensive
    Run while you can, Get a laser printer, its not worth it.

  • @nebuchadnezzar47
    @nebuchadnezzar47 3 года назад

    this channel died quicker than a child in africa

  • @rushoffman965
    @rushoffman965 5 лет назад

    Stop making random jump cuts

  • @householdemail1305
    @householdemail1305 4 месяца назад

    It will become fluid exchange circuits.

  • @nanotech_republika
    @nanotech_republika 5 лет назад

    Awesome video!